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- PrognomiQ
PrognomiQ Valuation, Funding & Investors
PrognomiQ is valued at $180M as of January 2026.
Last PrognomiQ valuation
$180M
Undisclosed stage · Jan 2026
Last PrognomiQ funding round
$12M
Undisclosed stage · Jan 2026
Cumulative funding PrognomiQ raised
$147M
across 4 funding rounds
Key investors in PrognomiQ
Invus
aMoon Fund
Bruker
Fidelity
T. Rowe Price
Wing Venture Capital
About PrognomiQ
PrognomiQ is a proteomics company generating multi-omics datasets for early disease detection. Headquartered in San Francisco, it maps proteomes alongside genomics and metabolomics to uncover biomarkers for cancer and neurodegenerative disorders. PrognomiQ's platform powered the largest human plasma proteome map published in 2023.
Founded
2020
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Services
Valuation
$180M (Jan 2026)
PrognomiQ Valuation
PrognomiQ is currently valued at $180M, based on its undisclosed-stage round in January 2026.
PrognomiQ valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Jan 2026 | Undisclosed stage | $180M |
PrognomiQ Funding History
PrognomiQ has raised a total of $147M across 4 funding rounds.
PrognomiQ's first fundraising round was a $55M undisclosed-stage round in September 2020. The most recent completed round was a $12M undisclosed-stage round in January 2026.
PrognomiQ funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Jan 2026 | Undisclosed stage | - | $12M | $180M | PrognomiQ is a healthcare company focused on harnessing multi-omics data to transform early detection, treatment selection, and monitoring of cancer and other complex diseases. The company develops early detection tests, including a multi-omics platform for lung cancer planned as a lab developed test (LDT) and later an In Vitro Diagnostics (IVD) test. PrognomiQ received a Clinical Laboratory Improvement Amendment (CLIA) license and is enrolling a prospective 15,000-subject study initiated in 2023 to support IVD registration. PrognomiQ raised $34 million in a Series D financing round led by Seer, Inc., with participation from a new large strategic investor in the diagnostics segment and existing investors including Catalio Capital Management, aMoon, Invus, and Bruker. One source reports this Series D at a $180 million valuation. The round brings total funding since the company's founding in September 2020 to more than $135 million, with proceeds advancing development of the lung cancer early detection test. Previously announced financings include a $46 million round to advance the multi-omics product pipeline. |
| Nov 2024 | Series D | Seer (lead); aMoon Fund; Invus; Catalio Capital Management; Bruker | $34M | - | PrognomiQ, a San Mateo, Calif.-based healthcare company spun out from Seer in September 2020, develops multi-omics platforms combining proteomics, genomics, and metabolomics for early detection, treatment selection, and monitoring of cancer and complex diseases, leveraging Seer's Proteograph Product Suite for deep unbiased proteomics data. The company focuses on a blood-based early detection test for lung cancer as an alternative to low-dose CT scans, targeting high-risk individuals, with plans to launch as a lab-developed test (LDT) following its recent Clinical Laboratory Improvement Amendment (CLIA) license and later as an in vitro diagnostic (IVD) test. On November 5, 2024, PrognomiQ closed a $34 million Series D financing round led by Seer, Inc., with participation from a new large strategic investor in diagnostics and existing investors aMoon Fund, Bruker, Catalio Capital Management, and Invus, bringing total funding since inception to over $135 million. Proceeds will advance development and commercialization of the lung cancer LDT, support enrollment in a prospective 15,000-subject study initiated in 2023 for IVD registration, and enhance the platform for other diseases. Concurrently, Isaac Ro joined the board as an independent director, bringing diagnostics expertise from roles at Catalio, Haystack Oncology, Sema4, Thrive Earlier Detection, and Goldman Sachs. PrognomiQ has demonstrated promising clinical data, including a study with over 2,500 participants showing 89% sensitivity and specificity for lung cancer detection, with 80% sensitivity for stage 1 disease. The company aims to address lung cancer, the leading cause of cancer deaths worldwide, by improving early detection to enhance survival rates amid limitations in current screening methods. |
| Mar 2022 | Undisclosed stage | Bruker (lead); Emerson Collective; Fidelity; aMoon Fund; Invus; T. Rowe Price; Catalio Capital Management; Maverick Ventures; Wing Venture Capital | $46M | - | PrognomiQ is a healthcare company founded in September 2020, focused on harnessing multi-omics data—including proteomic, genomic, and metabolomic data—to transform the early detection, treatment selection, and monitoring of cancer and other complex diseases. The company develops a multiomics platform and pipeline of products aimed at detecting cancer earlier and providing insights into disease mechanisms and host responses. On March 15, 2022, PrognomiQ raised $46 million in a financing round led by Bruker Corporation, with participation from new investor Catalio Capital Management and existing investors including aMoon Fund, Fidelity Management and Research Company LLC, T. Rowe Price Associates, Invus, Maverick Ventures, Emerson Collective, and Wing Venture Capital. This round nearly doubled the company's total funding to more than $101 million since inception. The proceeds are intended to accelerate development of the multi-omics platform and pipeline for early detection, treatment selection, and monitoring of multiple cancers. PrognomiQ plans to use funding to advance product development, with recent emphasis on an early detection test for lung cancer as a laboratory-developed test (LDT) and in vitro diagnostic (IVD), alongside expanding the platform to other diseases. |
| Sep 2020 | Undisclosed stage | aMoon Fund (lead); Seer; Emerson Collective; Fidelity; Invus; T. Rowe Price; Maverick Ventures; Bruker; Wing Venture Capital | $55M | - | PrognomiQ was spun out from Seer Inc. with a $55 million Series A financing led by aMoon, a Tel Aviv-based life sciences and healthcare venture capital firm. The round brought Prognomiq's total funding since its founding in 2020 to approximately $55 million (initial financing only disclosed; subsequent $46 million from Bruker followed). The company developed a multiomics platform designed to detect cancer and other complex diseases earlier in their development by extracting molecular insights from cell analysis. The parent company Seer Inc. was founded in 2017 by Harvard researcher Omid Farokhzad and MIT researcher Robert Langer, focusing on proteome analysis for early disease detection. The financing represented aMoon's entry into Prognomiq alongside Seer stockholders, establishing the spinout as an independent entity with a specialized focus on multiomics diagnostics. |
Who has invested in PrognomiQ?
10 investors have backed PrognomiQ across its funding rounds, including Invus, aMoon Fund, Bruker, Fidelity, T. Rowe Price and Wing Venture Capital.
Lead investors include Seer, Bruker and aMoon Fund.
PrognomiQ Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Sep 2020 | ||
| 3 | Participant | Sep 2020 | ||
| 3 | Lead | Sep 2020 | ||
| 2 | Lead | Sep 2020 | ||
| 2 | Participant | Sep 2020 | ||
| 2 | Participant | Sep 2020 | ||
| 2 | Participant | Sep 2020 | ||
| 2 | Participant | Mar 2022 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialPrognomiQ Competitors
PrognomiQ competitors include listed companies like CareDx, SOPHiA Genetics and GeneDx, and private ones like uBiome, Pepex Biomedical and Spark Neuro.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Private | - | - | $298M | - | ||
| Private | - | - | $100M | - | ||
| Private | - | - | $80M | - | ||
| Publicly listed | $380M | ($10M) | $2.8B | 5.3x | ||
| Publicly listed | $77M | ($65M) | $726M | 7.5x | ||
| Publicly listed | $428M | $7M | $3.1B | 6.8x |
PrognomiQ Public Comps
PrognomiQ is still privately-owned, but its public comps include Korro Bio, Ever Fortune.AI, Veraxa Biotech, ToolGen, OptimizeRx, Health Catalyst, Owlet, Airdoc, Cibus and Atrys Health.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $6M | ($112M) | 15.8x | 48.9x | (0.9x) | (1.1x) | |||
| $12M | $4M | 12.3x | - | 36.2x | - | |||
| $29K | ($79M) | 7313.2x | - | (2.6x) | - | |||
| $951K | ($26M) | 211.6x | - | (7.8x) | - | |||
| $109M | $16M | 1.3x | 1.4x | 8.5x | 5.9x | |||
| $311M | ($110M) | 0.6x | 0.8x | (1.8x) | 8.1x | |||
| $106M | ($36M) | 1.3x | 1.1x | (3.7x) | 15.1x | |||
| $26M | ($3M) | 1.5x | 1.5x | (11.9x) | - | |||
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Common questions about PrognomiQ
| When was PrognomiQ founded? | PrognomiQ was founded in 2020. |
| Where is PrognomiQ headquartered? | PrognomiQ is headquartered in San Francisco, CA, United States. |
| Is PrognomiQ publicly listed? | No, PrognomiQ is a private, VC-backed company. |
| What is PrognomiQ's valuation? | PrognomiQ was last valued at $180M in its undisclosed-stage round in January 2026. |
| How much funding has PrognomiQ raised? | PrognomiQ has raised $147M across 4 funding rounds. |
| What was PrognomiQ's last funding round? | PrognomiQ's last funding round was a $12M undisclosed-stage round in January 2026. |
| Who are PrognomiQ's investors? | PrognomiQ's investors include aMoon Fund, Invus, Bruker, Seer, Emerson Collective, Fidelity, T. Rowe Price, Catalio Capital Management, Maverick Ventures and Wing Venture Capital. |
| Which companies are comparable to PrognomiQ? | Companies comparable to PrognomiQ include uBiome, Pepex Biomedical, Spark Neuro, CareDx, SOPHiA Genetics and GeneDx. |
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