AviadoBio Funding, Investors & Competitors

AviadoBio has raised $115M across 3 funding rounds, most recently a $20M strategic investment round in October 2024.

Last AviadoBio funding round

$20M

Strategic investment · Oct 2024

Cumulative funding AviadoBio raised

$115M

across 3 funding rounds

Key investors in AviadoBio

  • F-Prime
  • Johnson & Johnson Innovation
  • Advent Life Sciences
  • Dementia Discovery Fund
  • LifeArc
  • New Enterprise Associates
  • EQT
  • Astellas Pharma

AviadoBio Overview

About AviadoBio

AviadoBio advances gene therapies for neurodegenerative diseases like frontotemporal dementia and amyotrophic lateral sclerosis from its London base. The pipeline leverages research from King’s College London and the UK Dementia Research Institute, targeting genetic mutations with AAV vectors for delivery to the central nervous system.


Founded

2019

HQ

United KingdomLondon

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

AviadoBio Funding History

AviadoBio has raised a total of $115M across 3 funding rounds.

AviadoBio's first fundraising round was a $16M seed round in January 2020. The most recent completed round was a $20M strategic investment round in October 2024.

AviadoBio funding rounds

AviadoBio funding rounds
DateStageInvestorsRaisedDeal Summary
Oct 2024Strategic investmentAstellas Pharma (lead)$20MAviadoBio is a London-based gene therapy company founded in 2019 from the King's College London lab of Professor Chris Shaw. The company specializes in minimally invasive stereotactic neurosurgical delivery of gene therapies directly to the brain, with a primary focus on treating neurological diseases. AviadoBio's lead asset, AVB-101, is an investigational adeno-associated virus (AAV)-based gene therapy in Phase 1/2 development for patients with frontotemporal dementia with progranulin mutations (FTD-GRN). In October 2024, Astellas Pharma and AviadoBio announced an exclusive option and license agreement, not a traditional equity funding round. Under the agreement, Astellas made a $20 million equity investment alongside up to $30 million in upfront payments to secure an exclusive worldwide license option for AVB-101. AviadoBio is eligible to receive up to $2.18 billion in license fees, milestone payments, and royalties if Astellas exercises the option. The deal structure reflects a mature-stage strategic partnership rather than a venture capital funding event. AviadoBio's previous funding included an $80 million Series A round completed in late 2021, following an initial $16.5 million seed financing. Investors in the company include New Enterprise Associates (NEA), Monograph Capital, F-Prime Capital, Johnson & Johnson Innovation (JJDC), SV Health Investor's Dementia Discovery Fund, Advent Life Sciences, EQT Life Sciences, and LifeArc Ventures.
Dec 2021Series AMonograph Capital (lead); New Enterprise Associates (lead); EQT; LifeArc; Advent Life Sciences; F-Prime; Johnson & Johnson Innovation; Dementia Discovery Fund$79MAviadoBio is a London-based biotech startup developing gene therapies for neurodegenerative disorders, including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), based on research from King’s College London. The company emerged from stealth in December 2021 with an $80 million Series A round led by New Enterprise Associates and Monograph Capital, following a $16.5 million seed round, with participation from investors including Advent Life Sciences, Dementia Discovery Fund, F-Prime Capital, Johnson & Johnson Innovation – JJDC, LSP, and LifArc. The funding aims to advance its lead FTD gene therapy program into human testing and progress preclinical assets like an ALS candidate, addressing challenges in widespread gene delivery to the nervous system. AviadoBio was incubated by F-Prime Capital and Johnson & Johnson Innovation, and is led by CEO Lisa Deschamps, formerly of Novartis Gene Therapies. The company faces competition, such as Passage Bio's Phase 1/2 FTD gene therapy. Subsequent rounds include a Series B of $72 million and later financings bringing total funding to around $127-149 million as of 2024.
Jan 2020SeedLifeArc; Advent Life Sciences; F-Prime; Johnson & Johnson Innovation; Dementia Discovery Fund$16MAviadoBio is a gene therapy company developing transformative medicines for neurodegenerative disorders such as frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Its platform combines next-generation gene therapy design, neuroscience expertise, and a neuroanatomy-led drug delivery approach using precision micro dosing for extensive gene expression. AviadoBio completed an initial $16.5 million (£12 million) seed financing with investors including Advent Life Sciences, Dementia Discovery Fund, F-Prime Capital, Johnson & Johnson Innovation – JJDC, Inc., and LifeArc. This preceded a $80 million Series A round in December 2021 led by New Enterprise Associates and co-led by Monograph Capital, with participation from LSP and the seed investors. The seed funds supported early development, leading to the Series A which advanced the lead FTD program into the clinic and preclinical assets.

Who has invested in AviadoBio?

9 investors have backed AviadoBio across its funding rounds, including F-Prime, Johnson & Johnson Innovation, Advent Life Sciences, Dementia Discovery Fund, LifeArc and New Enterprise Associates.

Lead investors include Astellas Pharma, Monograph Capital and New Enterprise Associates.


AviadoBio Investors

Investors in AviadoBio by funding rounds participated
InvestorHQRoundsRoleFirst check
LifeArcUnited KingdomLondon2ParticipantJan 2020
Advent Life SciencesUnited KingdomLondon2ParticipantJan 2020
F-PrimeUnited StatesUnited States2ParticipantJan 2020
Johnson & Johnson InnovationUnited StatesUnited States2ParticipantJan 2020
Dementia Discovery FundUnited KingdomLondon2ParticipantJan 2020
EQTSwedenStockholm1ParticipantDec 2021
Monograph CapitalUnited KingdomLondon1LeadDec 2021

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AviadoBio Competitors

AviadoBio competitors include listed companies like Roche and Johnson & Johnson, and private ones like Heyuan Biotechnology, ArsenalBio, Formation Bio and Immunai.

Public and private companies comparable to AviadoBio
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
RocheSwitzerlandSwitzerlandPublicly listed$77B$26B$351B4.9x
Heyuan BiotechnologyChinaShanghaiPrivate--$3B-
ArsenalBioUnited StatesUnited StatesPrivate--$1.9B-
Formation BioUnited StatesNew York City, NYPrivate--$1B-
ImmunaiUnited StatesNew York City, NYPrivate--$1B-
Johnson & JohnsonUnited StatesUnited StatesPublicly listed$94B$40B$651B6.8x

AviadoBio Public Comps

AviadoBio is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Merck, Roche, Novartis, AstraZeneca, Amgen, Novo Nordisk and Gilead Sciences.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Eli Lilly$65B$28B16.5x13.1x38.7x27.0x
Johnson & Johnson$94B$40B7.2x6.8x17.0x18.3x
AbbVie$61B$17B8.7x8.1x30.6x17.6x
Merck$65B$28B6.3x6.2x14.7x21.0x
Roche$77B$26B5.0x4.9x14.6x12.4x
Novartis$57B$22B5.5x5.5x14.2x13.3x
AstraZeneca$59B$19B4.8x4.5x14.6x12.7x
Amgen$37B$17B6.8x6.5x14.8x14.4x

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Common questions about AviadoBio

When was AviadoBio founded?AviadoBio was founded in 2019.
Where is AviadoBio headquartered?AviadoBio is headquartered in London, United Kingdom.
Is AviadoBio publicly listed?No, AviadoBio is a private, VC-backed company.
How much funding has AviadoBio raised?AviadoBio has raised $115M across 3 funding rounds.
What was AviadoBio's last funding round?AviadoBio's last funding round was a $20M strategic investment round in October 2024, led by Astellas Pharma.
Who are AviadoBio's investors?AviadoBio's investors include LifeArc, Advent Life Sciences, F-Prime, Johnson & Johnson Innovation, Dementia Discovery Fund, EQT, Monograph Capital, New Enterprise Associates and Astellas Pharma.
Which companies are comparable to AviadoBio?Companies comparable to AviadoBio include Roche, Heyuan Biotechnology, ArsenalBio, Formation Bio, Immunai and Johnson & Johnson.

See companies similar to AviadoBio

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