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Blueprint Medicines Valuation Multiples

Discover revenue and EBITDA valuation multiples for Blueprint Medicines and similar public comparables like Vivoryon Therapeutics, Pharming, and Galapagos.

Blueprint Medicines Overview

About Blueprint Medicines

Blueprint Medicines Corp is a biopharmaceutical company. It is developing medicines in the following focus areas; allergy, inflammation, oncology, and hematology. Its approved medicines, including Avyakit and Avyakyt, are given to patients living with systemic mastocytosis (SM) and PDGFRA Exon 18 mutant GIST in the U.S. and Europe. The company also has various other drug candidates in its pipeline such as BLU-808, BLU-222, BLU-956, and others that are being developed to treat mast cell diseases including SM and chronic urticaria, breast cancer, and other solid tumors. Geographically, it operates in the United States, which is its key revenue market, and Europe.


Founded

2008

HQ

United States of America
Employees

649

Financials

LTM Revenue $578M

LTM EBITDA -$136M

EV

$5.5B

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Blueprint Medicines Financials

Blueprint Medicines has a last 12-month revenue of $578M and a last 12-month EBITDA of -$136M.

In the most recent fiscal year, Blueprint Medicines achieved revenue of $509M and an EBITDA of $19.2M.

Blueprint Medicines expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Blueprint Medicines P&L

FY 2023 FY 2024 FY 2025 LTM NTM
Revenue $249M $509M XXX XXX XXX
Gross Profit $186M $241M XXX XXX XXX
Gross Margin 75% 47% XXX XXX XXX
EBITDA -$470M $19.2M XXX XXX XXX
EBITDA Margin -189% 4% XXX XXX XXX
Net Profit -$558M -$507M XXX XXX XXX
Net Margin -224% -100% XXX XXX XXX
Net Debt $19.4M $168M XXX XXX XXX

Financial data powered by Morningstar, Inc.

Blueprint Medicines Stock Performance

As of April 28, 2025, Blueprint Medicines's stock price is $88.

Blueprint Medicines has current market cap of $5.6B, and EV of $5.5B.

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Blueprint Medicines Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$5.5B $5.6B XXX XXX XXX XXX $-1.10

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Blueprint Medicines Valuation Multiples

As of April 28, 2025, Blueprint Medicines has market cap of $5.6B and EV of $5.5B.

Blueprint Medicines's trades at 9.4x LTM EV/Revenue multiple, and -40.2x LTM EBITDA.

Analysts estimate Blueprint Medicines's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

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Blueprint Medicines Financial Valuation Multiples

FY 2024 FY 2025E FY 2026E FY 2027E
EV $5.5B XXX XXX XXX
EV/Revenue 10.7x XXX XXX XXX
EV/EBITDA 283.6x XXX XXX XXX
P/E -83.5x XXX XXX XXX
P/E/Growth n/a XXX XXX XXX
EV/FCF -27.7x XXX XXX XXX

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Blueprint Medicines Valuation Multiples

Blueprint Medicines's NTM/LTM revenue growth is 38%

Blueprint Medicines's revenue per employee for the last fiscal year averaged $0.8M, while opex per employee averaged $1.1M for the same period.

Over next 12 months, Blueprint Medicines's ratio of sales and marketing spend to revenue is estimated to be  XXX , while its R&D spend to revenue to be  XXX .

Analysts estimate Blueprint Medicines's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

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Blueprint Medicines Operational Valuation Multiples

FY 2024 NTM FY 2025E FY 2026E FY 2027E
Revenue Growth 104% XXX XXX XXX XXX
EBITDA Margin 4% XXX XXX XXX XXX
EBITDA Growth -104% XXX XXX XXX XXX
Rule of 40 (SaaS-only) 41% XXX XXX XXX XXX
Revenue per Employee $0.8M XXX XXX XXX XXX
Opex per Employee $1.1M XXX XXX XXX XXX
S&M Expenses to Revenue 19% XXX XXX XXX XXX
G&A Expenses to Revenue 52% XXX XXX XXX XXX
R&D Expenses to Revenue 67% XXX XXX XXX XXX
Opex to Revenue 138% XXX XXX XXX XXX

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Blueprint Medicines Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Blueprint Medicines M&A and Investment Activity

Blueprint Medicines acquired  XXX companies to date.

Last acquisition by Blueprint Medicines was  XXXXXXXX, XXXXX XXXXX XXXXXX . Blueprint Medicines acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Blueprint Medicines

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Blueprint Medicines

When was Blueprint Medicines founded? Blueprint Medicines was founded in 2008.
Where is Blueprint Medicines headquartered? Blueprint Medicines is headquartered in United States of America.
How many employees does Blueprint Medicines have? As of today, Blueprint Medicines has 649 employees.
Who is the CEO of Blueprint Medicines? Blueprint Medicines's CEO is Ms. Kathryn Haviland.
Is Blueprint Medicines publicy listed? Yes, Blueprint Medicines is a public company listed on NAS.
What is the stock symbol of Blueprint Medicines? Blueprint Medicines trades under BPMC ticker.
When did Blueprint Medicines go public? Blueprint Medicines went public in 2015.
Who are competitors of Blueprint Medicines? Similar companies to Blueprint Medicines include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Blueprint Medicines? Blueprint Medicines's current market cap is $5.6B
What is the current revenue of Blueprint Medicines? Blueprint Medicines's last 12-month revenue is $578M.
What is the current EBITDA of Blueprint Medicines? Blueprint Medicines's last 12-month EBITDA is -$136M.
What is the current EV/Revenue multiple of Blueprint Medicines? Current revenue multiple of Blueprint Medicines is 9.4x.
What is the current EV/EBITDA multiple of Blueprint Medicines? Current EBITDA multiple of Blueprint Medicines is -40.2x.
What is the current revenue growth of Blueprint Medicines? Blueprint Medicines revenue growth between 2023 and 2024 was 104%.
Is Blueprint Medicines profitable? Yes, Blueprint Medicines is EBITDA-positive (as of the last 12 months).

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