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- Vertero
Vertero Funding, Investors & Competitors
Vertero has raised $112M across 5 funding rounds, most recently a $20M Series D in October 2025.
Last Vertero funding round
$20M
Series D · Oct 2025
Cumulative funding Vertero raised
$112M
across 5 funding rounds
Key investors in Vertero
Seventure Partners
Domain Associates
Longwood Fund
OneVentures
Taiho Ventures
Heritage Medical Center
UTokyo Innovation Platform
Kairos Ventures
About Vertero
Vertero is a biotechnology company advancing therapies for peripheral nervous system disorders including Parkinson's disease. The pipeline features small molecule candidates designed to delay symptom onset and slow disease progression through novel mechanisms targeting neurodegeneration. Vertero operates preclinical programs from research facilities in the United States.
Founded
2016
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Licensing
Sectors
Vertero Funding History
Vertero has raised a total of $112M across 5 funding rounds.
Vertero's first fundraising round was a $20M Series A in November 2016. The most recent completed round was a $20M Series D in October 2025.
Vertero funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Oct 2025 | Series D | OneVentures; Seventure Partners | $20M | Vertero is a biotechnology company developing novel oral small molecule therapeutics targeting peripheral drivers of neurodegenerative diseases, with a focus on Parkinson's disease. Its lead candidate, VT-5006, is a first-in-class, gut-selective small molecule designed to delay onset, slow progression, and preserve quality of life, showing strong safety and efficacy in preclinical studies. The company plans to initiate a Phase 1 clinical study in Q4 2025 and has an additional asset in early development targeting bile acid dysregulation for undisclosed indications. In 2025, Vertero raised $20 million in a Series D funding round led by new and existing investors including OneVentures, Seventure Partners, and private family investment offices. The proceeds will advance the VT-5006 program through Phase 1b clinical trials and into Phase 2 preparation, support ongoing drug discovery and pipeline expansion, and grow operational and R&D capacity. This funding facilitates a strategic shift toward breaking barriers in neurodegenerative diseases, leveraging expertise in brain-peripheral nervous system interplay. Previously, Vertero (formerly associated with Axial Therapeutics) completed a Series C round of $37.25 million on October 12, 2021, with investors including Health for Life Capital, Heritage Medical Center, Longwood Fund, and Seventure Partners. Recent investor activity includes a Series C - II in February 2025 with OneVentures, Seventure Partners, and Time BioVentures, indicating ongoing support in the neurodegenerative space. |
| Oct 2021 | Series C | OneVentures (lead); UTokyo Innovation Platform (lead); Autism Impact Fund; Taiho Ventures; Longwood Fund; Corundum Systems Biology; Domain Associates; Seventure Partners | $37M | Vertero Therapeutics is a biotherapeutics company founded in 2016 and based in Woburn, Massachusetts, that develops a novel class of therapeutics designed to treat neurological disorders by harnessing the gut-brain axis to target central nervous system diseases. The company has raised a total of $130.72M across 10 funding rounds according to one source, though another indicates $111.2M raised. As of March 2026, Vertero maintains a current valuation of $48M. The company's most recent documented funding round was a Series D or Series C-II (sources vary) for approximately $19-20M on February 11, 2025. |
| Jun 2019 | Series B | Taiho Ventures (lead) | $10M | - |
| Feb 2019 | Series B | Longwood Fund; Domain Associates; Seventure Partners; Heritage Medical Center | $25M | - |
| Nov 2016 | Series A | Domain Associates (lead); Longwood Fund (lead); Kairos Ventures; Heritage Medical Center | $20M | - |
Who has invested in Vertero?
10 investors have backed Vertero across its funding rounds, including Seventure Partners, Domain Associates, Longwood Fund, OneVentures, Taiho Ventures and Heritage Medical Center.
Lead investors include OneVentures, UTokyo Innovation Platform, Taiho Ventures, Domain Associates and Longwood Fund.
Vertero Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Nov 2016 | ||
| 3 | Lead | Nov 2016 | ||
| 3 | Participant | Feb 2019 | ||
| 2 | Lead | Jun 2019 | ||
| 2 | Lead | Oct 2021 | ||
| 2 | Participant | Nov 2016 | ||
| 1 | Participant | Nov 2016 | ||
| 1 | Participant | Oct 2021 | ||
This data is available for Pro users. Sign up to see all 10 Vertero investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialVertero Competitors
Vertero competitors include listed companies like Eli Lilly, Johnson & Johnson, AbbVie and Roche, and private ones like Biosplice Therapeutics and Intas Pharmaceuticals.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $65B | $28B | $1.2T | 14.3x | ||
| Publicly listed | $94B | $40B | $665B | 6.9x | ||
| Publicly listed | $61B | $17B | $515B | 8.8x | ||
| Publicly listed | $78B | $26B | $382B | 5.3x | ||
| Private | - | - | $12B | - | ||
| Private | $2B | - | $8.5B | - |
Vertero Public Comps
Vertero is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Roche, Merck, Novartis, AstraZeneca, Amgen, Gilead Sciences and Novo Nordisk.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $65B | $28B | 19.2x | 14.3x | 45.1x | 30.2x | |||
| $94B | $40B | 7.4x | 6.9x | 17.3x | 18.8x | |||
| $61B | $17B | 9.6x | 8.8x | 33.7x | 18.6x | |||
| $78B | $26B | 5.3x | 5.3x | 15.7x | 13.3x | |||
| $65B | $28B | 6.2x | 6.1x | 14.5x | 22.9x | |||
| $57B | $22B | 6.1x | 6.1x | 15.9x | 14.8x | |||
| $59B | $19B | 5.4x | 5.1x | 16.5x | 14.2x | |||
| $37B | $17B | 7.9x | 7.4x | 17.3x | 16.5x | |||
This data is available for Pro users. Sign up to see all Vertero competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Vertero
| When was Vertero founded? | Vertero was founded in 2016. |
| Where is Vertero headquartered? | Vertero is headquartered in Boston, MA, United States. |
| Is Vertero publicly listed? | No, Vertero is a private, VC-backed company. |
| How much funding has Vertero raised? | Vertero has raised $112M across 5 funding rounds. |
| What was Vertero's last funding round? | Vertero's last funding round was a $20M Series D in October 2025. |
| Who are Vertero's investors? | Vertero's investors include Longwood Fund, Domain Associates, Seventure Partners, Taiho Ventures, OneVentures, Heritage Medical Center, Kairos Ventures, Autism Impact Fund, Corundum Systems Biology and UTokyo Innovation Platform. |
| Which companies are comparable to Vertero? | Companies comparable to Vertero include Eli Lilly, Johnson & Johnson, AbbVie, Roche, Biosplice Therapeutics and Intas Pharmaceuticals. |
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