- Companies
- Singlera Genomics
Singlera Genomics Funding, Investors & Competitors
Singlera Genomics has raised $275M across 4 funding rounds, most recently a $45M Series B in June 2022.
Last Singlera Genomics funding round
$45M
Series B · Jun 2022
Cumulative funding Singlera Genomics raised
$275M
across 4 funding rounds
Key investors in Singlera Genomics
Green Pine Capital Partners
Lilly Asia Ventures
Prosperico Ventures
Linden Asset
CICC
DT Capital Partners
CD Capital
ShenZhen GTJA Investment Group
About Singlera Genomics
Singlera Genomics is a Hangzhou-based firm offering non-invasive tests for cancer detection and prenatal screening. Methylation sequencing platforms like cfMeDIP detect tumor DNA in blood for colorectal and liver cancers. Services extend to pre-implantation genetic diagnosis using IVF clinics in China and US.
Founded
2014
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Singlera Genomics Funding History
Singlera Genomics has raised a total of $275M across 4 funding rounds.
Singlera Genomics' first fundraising round was a $20M Series A in August 2016. The most recent completed round was a $45M Series B in June 2022.
Singlera Genomics funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Jun 2022 | Series B | Venture capitalist; FutureX Capital; Sansure Biotech; Junci Investment; Linden Asset; China Galaxy Securities; Best | $45M | - |
| Dec 2020 | Series B | CICC (lead); DT Capital Partners (lead); Furong Capital (lead); FTZ Fund; Proxima Ventures Ltd; Wuxi Capital; Prosperico Ventures; Huamei International; Linden Asset; FutureX Skyline Capital; Green Pine Capital Partners | $150M | Singlera Genomics, founded in 2014, develops non-invasive genetic testing and molecular diagnostic technologies focused on early cancer screening using a patented methylation detection platform for circulating tumor DNA (ctDNA). The company announced a $150 million Series B financing round on December 15, 2020, led by CICC Kai Tak Innovative Biomedicine Fund, with co-leads Detong Capital (DT Capital Partners) and Furong Investment (Furong Capital). Other participants included Huamei International, Linden Asset Group, Wuxi Capital, FutureX Skyline Capital, Shanghai Free Trade Zone Fund (FTZ Fund), and follow-on investments from Series A investors Green Pine Capital Partners, Prosperico Ventures, and Proxima Ventures Ltd. The proceeds are designated for expanding the early cancer screening product pipeline, advancing product registration and commercialization, and conducting large-scale prospective studies for pan-cancer early screening. In July 2020, Singlera collaborated with Fudan University to publish results on its PanSeer ctDNA methylation technology, validating early cancer detection in a large population cohort up to four years before conventional diagnosis. Singlera Genomics had previously raised a $60 million Series A-plus round in early 2018 co-led by Green Pine Capital and Prosperico Ventures, with participation from Lilly Asia Ventures, Jointown Pharmaceutical Group, and UCF Medical Investment, following an initial $20 million Series A in 2016 led by Lilly Asia Ventures. The company maintains dual headquarters in San Diego and Shanghai, with technologies including single-cell sequencing, bioinformatics, and DNA methylation for products like PanSeer and a second-generation NIPT assay developed with Yale University. Post-Series B, Singlera pursued international expansion, including strategic partnerships in 2022 with Breakthrough Genomics for the U.S. market and in 2023 with Clinomics USA for early cancer detection services, alongside ongoing clinical studies like GUIDE and ColonES. Cumulative funding reached approximately $278 million across eight rounds by a later Series C in July 2024. |
| Mar 2018 | Series A | Green Pine Capital Partners (lead); Prosperico Ventures (lead); ShenZhen GTJA Investment Group; Prox Ventures; Jointown Pharmaceutical; Lilly Asia Ventures; UCF Medical Investment | $60M | Singlera Genomics, founded in 2014 in San Diego with operations in California and Shanghai, develops non-invasive genetic testing technologies focused on early cancer screening using a patented DNA methylation detection platform for tumors including lung, colorectal, liver, stomach, esophageal, pancreatic, and thyroid cancers. The company raised approximately $60 million in a Series A+ financing round around March 27, 2018, led by Green Pine Capital Partners and Prosperico Ventures, with participation from Jointown Pharmaceutical Group, Lilly Asia Ventures, Prox Ventures, ShenZhen GTJA Investment Group, and UCF Medical Investment. This funding supported the advancement of their single-cell sequencing, DNA methylation, and bioinformatics technologies for molecular diagnostics and liquid biopsy applications. Later, Singlera Genomics secured a $150 million Series B round announced in 2020, led by new investors like Huamei International, with follow-on from Series A investors including Green Pine Capital, Prosperico Ventures, and Proxima Ventures, to expand early cancer screening R&D, product commercialization, and large-scale prospective studies. The company has continued fundraising, reaching over $278 million across 8 rounds by 2024, including a Series C in July 2024. Singlera positions itself in the competitive non-invasive diagnostics market, emphasizing early tumor detection and prevention through proprietary platforms. Green Pine Capital Partners, established in 2007 in Shenzhen, China, participated as a lead highlighting its focus on valuable investments in biotech. |
| Aug 2016 | Series A | Lilly Asia Ventures (lead); CD Capital; Shanghai Angel Capital Guiding Fund; Green Pine Capital Partners | $20M | Singlera Genomics is a non-invasive genetic testing company co-founded by Dr. Yuan Gao (on leave from Johns Hopkins University) and Dr. Kun Zhang (Associate Professor at UCSD) in June 2014, based in La Jolla, California. The company's proprietary technology focuses on non-invasive prenatal testing of chromosomal aneuploidy and simultaneous measurement of fetal DNA fraction in a single test, with potential to significantly lower testing costs, reduce false negative rates, and cut turnaround time to one to two days. In August 2016, Singlera announced a $20 million Series A financing round led by Lilly Asia Ventures, with participation from CD Capital, Green Pine Capital Partners, and Shanghai Angel Capital Guiding Fund. In January 2016, prior to the Series A close, the company signed a Clinical Trial Agreement with Yale University School of Medicine to evaluate the technology's effectiveness in prenatal testing, particularly for patients with obesity-related complications and low fetal fraction. The company later raised $150 million in a Series B round in 2020, demonstrating strong investor confidence in its technology and market opportunity in non-invasive genetic testing. |
Who has invested in Singlera Genomics?
24 investors have backed Singlera Genomics across its funding rounds, including Green Pine Capital Partners, Lilly Asia Ventures, Prosperico Ventures, Linden Asset, CICC and DT Capital Partners.
Lead investors include CICC, DT Capital Partners, Furong Capital, Green Pine Capital Partners, Prosperico Ventures and 1 other investor.
Singlera Genomics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Aug 2016 | ||
| 2 | Lead | Mar 2018 | ||
| 2 | Lead | Aug 2016 | ||
| 2 | Participant | Dec 2020 | ||
| 1 | Participant | Dec 2020 | ||
| 1 | Participant | Dec 2020 | ||
| 1 | Participant | Jun 2022 | ||
| 1 | Participant | Mar 2018 | ||
| 1 | Participant | Jun 2022 | ||
| 1 | Participant | Dec 2020 | ||
| 1 | Participant | Aug 2016 | ||
| 1 | Participant | Mar 2018 | ||
| 1 | Lead | Dec 2020 | ||
This data is available for Pro users. Sign up to see all 24 Singlera Genomics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialSinglera Genomics Competitors
Singlera Genomics competitors include listed companies like Illumina, 10x Genomics, BillionToOne and Personalis, and private ones like BGI Group and Sangon Biotech.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $4.3B | $1.4B | $36B | 8.3x | ||
| Publicly listed | $643M | ($16M) | $10B | 15.2x | ||
| Publicly listed | $305M | $12M | $5B | 11.1x | ||
| Publicly listed | $70M | ($78M) | $1.8B | 20.3x | ||
| Private | - | - | $1.6B | - | ||
| Private | $102M | - | $1.4B | 13.7x |
Singlera Genomics Public Comps
Singlera Genomics is still privately-owned, but its public comps include Roche, Merck KGaA, Natera, Illumina, Guardant Health, Sartorius, Bio-Techne, Twist Bioscience, 10x Genomics and Demant.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $77B | $26B | 4.9x | 4.9x | 14.5x | 12.2x | |||
| $24B | $5.3B | 3.1x | 3.1x | 14.2x | 10.7x | |||
| $2.3B | ($266M) | 22.7x | 19.1x | (196.6x) | (264.1x) | |||
| $4.3B | $1.4B | 8.6x | 8.3x | 26.5x | 29.3x | |||
| $982M | ($408M) | 25.2x | 19.8x | (60.6x) | (127.0x) | |||
| $4.1B | $1.1B | 5.7x | 5.5x | 22.1x | 18.5x | |||
| $1.2B | $343M | 9.4x | 9.3x | 33.1x | 26.3x | |||
| $377M | ($63M) | 29.2x | 24.2x | (173.3x) | (340.6x) | |||
This data is available for Pro users. Sign up to see all Singlera Genomics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Singlera Genomics
| When was Singlera Genomics founded? | Singlera Genomics was founded in 2014. |
| Where is Singlera Genomics headquartered? | Singlera Genomics is headquartered in San Diego, CA, United States. |
| Is Singlera Genomics publicly listed? | No, Singlera Genomics is a private, VC-backed company. |
| How much funding has Singlera Genomics raised? | Singlera Genomics has raised $275M across 4 funding rounds. |
| What was Singlera Genomics' last funding round? | Singlera Genomics' last funding round was a $45M Series B in June 2022. |
| Who are Singlera Genomics' investors? | Singlera Genomics' investors include Green Pine Capital Partners, Prosperico Ventures, Lilly Asia Ventures, Linden Asset, FTZ Fund, Proxima Ventures Ltd, Venture capitalist, ShenZhen GTJA Investment Group, FutureX Capital, Wuxi Capital and 14 others. |
| Which companies are comparable to Singlera Genomics? | Companies comparable to Singlera Genomics include Illumina, 10x Genomics, BillionToOne, Personalis, BGI Group and Sangon Biotech. |
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