Reata Pharmaceuticals Acquisition, Valuation, Funding & Investors

Reata Pharmaceuticals was acquired by Biogen for $7.3B in July 2023.

Reata Pharmaceuticals acquisition price

$7.3B

Acquired by Biogen · Jul 2023

Cumulative funding Reata Pharmaceuticals raised

$175M

across 6 funding rounds

Key investors in Reata Pharmaceuticals

  • Novo Holdings
  • CPMG
  • STARTech Early Ventures

Reata Pharmaceuticals Overview

About Reata Pharmaceuticals

Reata Pharmaceuticals is a biopharmaceutical company based in Plano, Texas, that has been a wholly owned subsidiary of Biogen since September 2023. It was founded in 2002 in the Dallas area and developed oral small-molecule drugs that activate the antioxidant transcription factor Nrf2 and suppress the pro-inflammatory factor NF-kB. Its lead product, Skyclarys (omaveloxolone), was approved by the US Food and Drug Administration in February 2023 as the first treatment for Friedreich's ataxia, a rare inherited neurodegenerative disease, and has since been approved in the European Union and other markets. Its earlier candidate bardoxolone methyl was studied in chronic kidney disease and Alport syndrome under licensing partnerships with Kyowa Kirin in Asia and AbbVie. Before Skyclarys the company earned collaboration and licence revenue, which was $2.2 million in 2022, and it now earns revenue from product sales. Reata raised about $175 million privately from investors including CPMG and Novo A/S, listed on Nasdaq in 2016 and was acquired by Biogen for $172.50 per share, an enterprise value of about $7.3 billion.


Founded

2002

HQ

United StatesPlano

Status

Acquired

Customer focus

B2C

Revenue model

Product sales

Valuation

$7.3B (acquired Jul 2023)

Reata Pharmaceuticals Acquisition

Reata Pharmaceuticals was acquired by Biogen for $7.3B on 28 July 2023.

Before the acquisition Reata Pharmaceuticals had raised $175M across 6 funding rounds.

Biogen agreed on 28 July 2023 to acquire Reata Pharmaceuticals for $172.50 per share in cash, a transaction with an enterprise value of about $7.3 billion and an equity value of about $7.5 billion. The deal gave Biogen Skyclarys (omaveloxolone), which the US Food and Drug Administration had approved in February 2023 as the first and only treatment for Friedreich's ataxia, a rare inherited neurodegenerative disease; the drug was under regulatory review in Europe at signing. Biogen saw the product as a fit with its rare disease and neuromuscular franchise, which includes Spinraza, and expected the acquisition to be significantly accretive to earnings from 2025. The acquisition was completed on 26 September 2023 and Reata's shares were delisted from Nasdaq. Reata was founded in 2002 and is based in Plano, Texas, and it developed small-molecule drugs that activate the Nrf2 pathway, including bardoxolone methyl for chronic kidney disease. Before the launch of Skyclarys its revenue came from collaboration agreements with Kyowa Kirin and AbbVie and amounted to $2.2 million in 2022.

Reata Pharmaceuticals acquisition details
AcquirerDateTypePrice
28 Jul 2023Strategic M&A$7.3B

Sources: sec.gov, labiotech.eu, cravath.com, en.wikipedia.org

Reata Pharmaceuticals Funding History

Reata Pharmaceuticals has raised a total of $175M across 6 funding rounds.

Reata Pharmaceuticals' first fundraising round was a $5M Series A in September 2003. The most recent completed round was a $78M undisclosed-stage round in July 2010.

Reata Pharmaceuticals funding rounds

Reata Pharmaceuticals funding rounds
DateStageInvestorsRaisedDeal Summary
Jul 2010Undisclosed stageNovo Holdings (lead); CPMG (lead)$78MReata Pharmaceuticals completed a $78 million equity financing on 12 July 2010, co-led by CPMG, Inc. and Novo A/S, the investment arm of the Novo Nordisk Foundation. The company said the money gave it enough capital to fully fund the pivotal trial programme for bardoxolone methyl in patients with advanced chronic kidney disease and type 2 diabetes, while also moving other pipeline candidates into clinical development. It was Reata's sixth private round and took its total funding since inception to about $180 million, following $32 million raised in March 2009. Later in 2010 Reata signed a licensing agreement with Abbott for bardoxolone methyl outside the United States and Asia, adding to its existing Asian partnership with Kyowa Hakko Kirin. Reata was then based in Irving, Texas. Reata was founded in 2002 in the Dallas area and developed oral drugs that activate the antioxidant transcription factor Nrf2 and suppress the inflammatory factor NF-kB, led by bardoxolone methyl. The company later listed on Nasdaq in 2016, won FDA approval for Skyclarys (omaveloxolone) for Friedreich's ataxia in 2023 and was acquired by Biogen that year for about $7.3 billion.
Mar 2009Undisclosed stage-$32MReata Pharmaceuticals closed $32.0 million in the first tranche of a private financing, announced on 26 March 2009. The company did not name the investors in its announcement. It raised the money to capture the opportunity created by encouraging clinical data for bardoxolone methyl in chronic kidney disease, and used it to advance Phase 2b trials of the drug in patients with advanced chronic kidney disease and type 2 diabetes. Reata also expanded its team at the same time, hiring Eric Grossman as vice president of clinical development and medical affairs. The round was followed in July 2010 by a $78 million financing led by Novo A/S and CPMG to fund pivotal trials. Reata was founded in 2002 in the Dallas area and developed oral drugs that activate the antioxidant transcription factor Nrf2 and suppress the inflammatory factor NF-kB, led by bardoxolone methyl. The company later listed on Nasdaq in 2016, won FDA approval for Skyclarys (omaveloxolone) for Friedreich's ataxia in 2023 and was acquired by Biogen that year for about $7.3 billion.
Jul 2007Series ECPMG (lead); Novo Holdings (lead)$25MReata Pharmaceuticals closed a $25 million Series E financing on 6 July 2007, led by its existing investors CPMG, Inc. and Novo A/S. The Irving, Texas, company was developing novel oral drugs for cancer, inflammation and neurodegenerative diseases based on synthetic triterpenoids that act on the Nrf2 and NF-kB pathways. The capital funded clinical trials of its lead compound bardoxolone methyl, which was being tested in cancer patients before the company shifted its focus to chronic kidney disease. CPMG, formed from the Dallas firm Cardinal Investment Company, had led the company's $22.6 million round in 2006, and Novo, the investment arm of the Novo Nordisk Foundation, had first invested in that round. The round brought Reata's private funding to about $65 million since its founding. Reata was founded in 2002 in the Dallas area and developed oral drugs that activate the antioxidant transcription factor Nrf2 and suppress the inflammatory factor NF-kB, led by bardoxolone methyl. The company later listed on Nasdaq in 2016, won FDA approval for Skyclarys (omaveloxolone) for Friedreich's ataxia in 2023 and was acquired by Biogen that year for about $7.3 billion.
Aug 2006Series DCPMG (lead); Novo Holdings$23MReata Pharmaceuticals announced on 4 August 2006 that it had closed a $22.6 million private financing led by Cardinal Investment Company, the Dallas investment firm later known as CPMG. Novo A/S, the Copenhagen-based life science investment arm of the Novo Nordisk Foundation now known as Novo Holdings, joined as a new investor alongside previous shareholders. Chief executive Warren Huff said the round would allow the company to continue advancing its development programmes. At the time Reata was developing oral synthetic triterpenoid drugs for cancer, inflammation and neurodegenerative diseases, with bardoxolone methyl in early clinical trials. The round followed $5.2 million of start-up funding in 2003 and $12 million in 2004, and Cardinal and Novo went on to lead the company's later private rounds. Reata was founded in 2002 in the Dallas area and developed oral drugs that activate the antioxidant transcription factor Nrf2 and suppress the inflammatory factor NF-kB, led by bardoxolone methyl. The company later listed on Nasdaq in 2016, won FDA approval for Skyclarys (omaveloxolone) for Friedreich's ataxia in 2023 and was acquired by Biogen that year for about $7.3 billion.
Nov 2004Series B-$12MReata Pharmaceuticals raised $12 million in November 2004, its second private financing after $5.2 million of start-up funding in September 2003. The investors in this round were not publicly named in the sources available. The capital supported preclinical and early clinical development of the company's lead synthetic triterpenoid, bardoxolone methyl, which was then being studied as a cancer treatment. Reata was still a small company based in the Dallas area, and it went on to raise $22.6 million in August 2006 in a round led by Cardinal Investment Company with Novo A/S as a new investor. In total it raised about $175 million in six private rounds before its initial public offering. Reata was founded in 2002 in the Dallas area and developed oral drugs that activate the antioxidant transcription factor Nrf2 and suppress the inflammatory factor NF-kB, led by bardoxolone methyl. The company later listed on Nasdaq in 2016, won FDA approval for Skyclarys (omaveloxolone) for Friedreich's ataxia in 2023 and was acquired by Biogen that year for about $7.3 billion.
Sep 2003Series ASTARTech Early Ventures$5MReata Pharmaceuticals completed $5.2 million of start-up financing in September 2003, its first institutional funding. The round was led by Ojai Goliad with participation from STARTech Early Ventures, the Richardson, Texas, seed fund and incubator that backed technology companies in the Dallas area. The money allowed the company, then less than a year old, to license and begin developing synthetic triterpenoid compounds discovered at Dartmouth College and the MD Anderson Cancer Center. Reata went on to raise $12 million in November 2004, $22.6 million in August 2006, $25 million in July 2007, $32 million in March 2009 and $78 million in July 2010, for about $175 million in private funding before its initial public offering. Reata was founded in 2002 in the Dallas area and developed oral drugs that activate the antioxidant transcription factor Nrf2 and suppress the inflammatory factor NF-kB, led by bardoxolone methyl. The company later listed on Nasdaq in 2016, won FDA approval for Skyclarys (omaveloxolone) for Friedreich's ataxia in 2023 and was acquired by Biogen that year for about $7.3 billion.

Who has invested in Reata Pharmaceuticals?

3 investors have backed Reata Pharmaceuticals across its funding rounds, including Novo Holdings, CPMG and STARTech Early Ventures.

Lead investors include Novo Holdings and CPMG.


Reata Pharmaceuticals Investors

Investors in Reata Pharmaceuticals by funding rounds participated
InvestorHQRoundsRoleFirst check
Novo HoldingsDenmarkCopenhagen3LeadAug 2006

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Reata Pharmaceuticals Competitors

Reata Pharmaceuticals competitors include listed companies like Huadong Medicine, Bachem, Kiniksa Pharmaceuticals and Gedeon Richter, and private ones like Intas Pharmaceuticals and Biocon Biologics.

Public and private companies comparable to Reata Pharmaceuticals
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Huadong MedicineChinaChinaPublicly listed$6.5B$758M$7.3B1.1x
BachemSwitzerlandSwitzerlandPublicly listed$851M$250M$7.3B6.8x
Kiniksa PharmaceuticalsUnited StatesUnited StatesPublicly listed$678M$90M$7.4B6.8x
Gedeon RichterHungaryHungaryPublicly listed$2.9B$1B$7.2B2.2x
Intas PharmaceuticalsIndiaAhmedabadPrivate$2B-$8.5B-
Biocon BiologicsIndiaBangalorePrivate$1.1B$163M$5.5B5.1x

Reata Pharmaceuticals Public Comps

Reata Pharmaceuticals is no longer listed, but its public comps include Huadong Medicine, Bachem, Caris Life Sciences, Kiniksa Pharmaceuticals, Gedeon Richter, Cytokinetics, Grifols, Indivior Pharmaceuticals, Abivax and Amneal Pharmaceuticals.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Huadong Medicine$6.5B$758M1.1x1.1x9.3x9.0x
Bachem$851M$250M8.8x6.8x30.0x22.5x
Caris Life Sciences$812M($5M)8.5x6.9x(1354.5x)40.1x
Kiniksa Pharmaceuticals$678M$90M10.1x6.8x75.4x44.3x
Gedeon Richter$2.9B$1B2.2x2.2x6.1x5.7x
Cytokinetics$88M($719M)86.6x50.5x(10.6x)(11.1x)
Grifols$8.4B$1.8B2.4x2.3x11.0x9.4x
Indivior Pharmaceuticals$1.2B$282M6.2x6.2x27.4x15.3x

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Common questions about Reata Pharmaceuticals

When was Reata Pharmaceuticals founded?Reata Pharmaceuticals was founded in 2002.
Where is Reata Pharmaceuticals headquartered?Reata Pharmaceuticals is headquartered in Plano, United States.
Is Reata Pharmaceuticals publicly listed?No, Reata Pharmaceuticals was acquired by Biogen in July 2023.
Who acquired Reata Pharmaceuticals?Reata Pharmaceuticals was acquired by Biogen in July 2023.
How much was Reata Pharmaceuticals acquired for?Reata Pharmaceuticals was acquired for $7.3B in July 2023.
How much funding has Reata Pharmaceuticals raised?Reata Pharmaceuticals has raised $175M across 6 funding rounds.
What was Reata Pharmaceuticals' last funding round?Reata Pharmaceuticals' last funding round was a $78M undisclosed-stage round in July 2010, led by Novo Holdings and CPMG.
Who are Reata Pharmaceuticals' investors?Reata Pharmaceuticals' investors include Novo Holdings, CPMG and STARTech Early Ventures.
Which companies are comparable to Reata Pharmaceuticals?Companies comparable to Reata Pharmaceuticals include Huadong Medicine, Bachem, Kiniksa Pharmaceuticals, Gedeon Richter, Intas Pharmaceuticals and Biocon Biologics.

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