PharmaFluidics Acquisition, Valuation, Funding & Investors

PharmaFluidics was acquired by Thermo Fisher Scientific in November 2021.

PharmaFluidics acquisition price

Undisclosed

Acquired by Thermo Fisher Scientific · Nov 2021

Cumulative funding PharmaFluidics raised

$13M

across 3 funding rounds

Key investors in PharmaFluidics

  • PMV
  • Qbic Fund
  • Innovation Fund
  • Theodorus III
  • SFPI-FPIM
  • Annie Vereecken
  • Qbic
  • Rudi Mariën

PharmaFluidics Overview

About PharmaFluidics

PharmaFluidics is a Belgian biotech company that develops micro-chip based chromatography columns for analytical separation used in biomarker discovery, diagnostics, and drug development. Its proprietary silicon wafer-based Pillar Array technology offers improved consistency, reproducibility, miniaturization, and sensitivity compared to conventional nano-LC columns, serving applications in proteomics, metabolomics, and single-cell analysis. The company has established itself as a supplier of nano-LC columns for deep and precision/clinical proteomics, targeting instrument manufacturers and research customers in these high-value niche markets.


Founded

2010

HQ

BelgiumBelgium

Status

Acquired

Customer focus

B2B

Revenue model

Product sales

PharmaFluidics Acquisition

PharmaFluidics was acquired by Thermo Fisher Scientific for an undisclosed price on 2 November 2021.

Before the acquisition PharmaFluidics had raised $13M across 3 funding rounds.

Thermo Fisher Scientific announced on 1 November 2021 that it had acquired PharmaFluidics NV, the Ghent, Belgium-based developer of the µPAC range of micro-chip based liquid chromatography columns. Financial terms were not disclosed. The acquisition added patterned microchip-based separation technology to Thermo Fisher's chromatography and mass spectrometry portfolio, where the µPAC columns are used to improve separation performance and sensitivity in proteomics, biomarker discovery and drug-development workflows. µPAC columns are produced by etching the interstitial volume out of a solid silicon wafer to leave a perfectly ordered array of pillars, giving reproducible, robust nano-LC separations that identify substantially more compounds in complex biological samples than conventional packed columns. PharmaFluidics was founded in 2010 as a spin-off of Vrije Universiteit Brussel and had raised roughly €10.5 million from Qbic, PMV, SFPI-FPIM, Theodorus, the Innovation Fund, Volksvermogen and the investor groups of Annie Vereecken and Rudi Mariën before the sale, which delivered an exit for those shareholders. The company began shipping commercial columns in September 2017 and remained a small, early-commercial business at the time of the acquisition, with sales in the hundreds of thousands of euro. Its operations were integrated into Thermo Fisher's chromatography consumables business.

PharmaFluidics acquisition details
AcquirerDateType
2 Nov 2021Strategic M&A

Sources: thermofisher.mediaroom.com, genomeweb.com, heranpartners.com

PharmaFluidics Funding History

PharmaFluidics has raised a total of $13M across 3 funding rounds.

PharmaFluidics' first fundraising round was a $700K pre-seed round in July 2014. The most recent completed round was a $9M Series A in January 2018.

PharmaFluidics funding rounds

PharmaFluidics funding rounds
DateStageInvestorsRaisedDeal Summary
Jan 2018Series ASFPI-FPIM (lead); Annie Vereecken; Theodorus III; PMV; Innovation Fund; Qbic; Rudi Mariën$9MPharmaFluidics, a micro-chip chromatography company, raised 7.3 million euro in a financing round closed around late 2017 to early 2018 from investors including SFPI-FPIM, Heran (Annie Vereecken), RMM (Rudi Mariën), PMV, Qbic, Theodorus III, Innovation Fund, and Volksvermogen. The funds supported intensified commercialization, further development of the Pillar Array technology platform, expansion of the µPAC product range, and scaling up production and global sales. The µPAC columns began shipping commercially in September 2017, with initial promising sales targeting high-value niche markets like proteomics and metabolomics profiling. PharmaFluidics' µPAC™ micro-Chip chromatography columns offer unique performance in robustness, reproducibility, miniaturization, and sensitivity, enabling applications such as pooled proteomics data for big data analysis, point-of-care nano-LC-MS, and single-cell analyses. The company extended its product range with trapping columns and new stationary phases while scaling supply chain and production capacity. In 2018, PharmaFluidics established itself as a leading supplier of nano-LC columns for deep proteomics and precision/clinical proteomics.
Jan 2017SeedPMV; Qbic Fund$3MPharmaFluidics NV is a Belgian biotech company developing µPAC™ micro-chip based chromatography cartridges for analytical separation in biomarker discovery, diagnostics, and drug development applications. The company's proprietary silicon wafer-based technology provides improved resolution and robustness compared to conventional nano-LC columns used in proteomics, metabolomics, and lipidomics analysis. In January 2017, PharmaFluidics raised €2.7 million in funding from a consortium of existing and new shareholders including Qbic Arkiv Fund, PMV (the Flemish investment company), Theodorus Fund, Innovation Fund, and Volksvermogen. The company later closed an additional €7.2 million round later that same year. The proceeds were directed toward expanding the team and accelerating commercialization of the µPAC™ product line. By late 2017, PharmaFluidics had begun product shipments and reported €326,000 in sales, more than doubling from €158,000 in 2016, indicating early traction in commercial deployment. The company pursued a focused go-to-market strategy targeting high-value niche markets in proteomics and metabolomics profiling through direct sales and partnerships with leading instrument manufacturers.
Jul 2014Pre-seedQbic Fund (lead); Theodorus III; PMV; Innovation Fund$700KPharmaFluidics NV raised about €500,000 of seed capital in mid-2014 from Qbic Fund, the inter-university venture fund associated with Ghent University, Vrije Universiteit Brussel and Antwerp University, and PMV, the Flemish government's investment company, with the university spin-off funds Theodorus and the Innovation Fund also recorded as early shareholders. The financing was the company's first external round and funded the transfer of its pillar-array chromatography technology from the laboratory towards a manufacturable product. PharmaFluidics was founded in 2010 as a spin-off of Vrije Universiteit Brussel, based on research by Professor Gert Desmet's group, and is headquartered in Ghent, Belgium. The company develops µPAC micro-chip based liquid-chromatography columns in which the separation bed is etched from a silicon wafer as a perfectly ordered array of pillars, giving higher resolution, reproducibility and robustness than packed nano-LC columns used in proteomics, metabolomics and biomarker research. At the time of the seed round the company was pre-revenue with a small team; it went on to raise €2.7 million in January 2017 and €7.3 million in early 2018, shipped its first commercial columns in September 2017, and was acquired by Thermo Fisher Scientific in November 2021.

Who has invested in PharmaFluidics?

8 investors have backed PharmaFluidics across its funding rounds, including PMV, Qbic Fund, Innovation Fund, Theodorus III, SFPI-FPIM and Annie Vereecken.

Lead investors include SFPI-FPIM and Qbic Fund.


PharmaFluidics Investors

Investors in PharmaFluidics by funding rounds participated
InvestorHQRoundsRoleFirst check
PMVBelgiumBrussels3ParticipantJul 2014
Theodorus IIIBelgiumBrussels2ParticipantJul 2014
Innovation FundBelgiumBrussels2ParticipantJul 2014
Qbic FundBelgiumGhent2LeadJul 2014
SFPI-FPIMBelgiumBrussels1LeadJan 2018
Annie VereeckenBelgiumAntwerp1ParticipantJan 2018

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PharmaFluidics Competitors

PharmaFluidics competitors include listed companies like Syngene, Merck KGaA and Wuxi AppTec, and private ones like Aragen Life Sciences, VectorBuilder and Safe Medical Evaluation.

Public and private companies comparable to PharmaFluidics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
SyngeneIndiaIndiaPublicly listed$384M$90M$1.8B4.4x
Aragen Life SciencesIndiaHyderabadPrivate$179M$48M$1.4B7.8x
VectorBuilderUnited StatesChicago, ILPrivate--$1B-
Safe Medical EvaluationChinaBeijingPrivate--$574M-
Merck KGaAGermanyGermanyPublicly listed$24B$5.2B$72B3.4x
Wuxi AppTecChinaChinaPublicly listed$6.8B$4B$68B7.0x

PharmaFluidics Public Comps

PharmaFluidics is no longer listed, but its public comps include Merck KGaA, Wuxi AppTec, Lonza Group, Samsung BioLogics, IQVIA, Illumina, Divi's Laboratories, Wuxi Biologics, Sartorius and Sartorius.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Merck KGaA$24B$5.2B3.5x3.4x16.1x12.0x
Wuxi AppTec$6.8B$4B9.1x7.0x15.4x13.5x
Lonza Group$8B$2.5B7.7x7.1x24.6x21.4x
Samsung BioLogics$3.4B$2B15.3x13.0x25.4x24.7x
IQVIA$16B$3.4B3.6x3.4x17.2x14.7x
Illumina$4.3B$1.4B7.6x7.2x23.4x25.4x
Divi's Laboratories$1.1B$382M27.9x24.7x81.4x70.0x
Wuxi Biologics$3.3B$1.3B7.5x6.5x18.6x16.9x

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Common questions about PharmaFluidics

When was PharmaFluidics founded?PharmaFluidics was founded in 2010.
Where is PharmaFluidics headquartered?PharmaFluidics is headquartered in Belgium.
Is PharmaFluidics publicly listed?No, PharmaFluidics was acquired by Thermo Fisher Scientific in November 2021.
Who acquired PharmaFluidics?PharmaFluidics was acquired by Thermo Fisher Scientific in November 2021.
How much funding has PharmaFluidics raised?PharmaFluidics has raised $13M across 3 funding rounds.
What was PharmaFluidics' last funding round?PharmaFluidics' last funding round was a $9M Series A in January 2018, led by SFPI-FPIM.
Who are PharmaFluidics' investors?PharmaFluidics' investors include PMV, Theodorus III, Innovation Fund, Qbic Fund, SFPI-FPIM, Annie Vereecken, Qbic and Rudi Mariën.
Which companies are comparable to PharmaFluidics?Companies comparable to PharmaFluidics include Syngene, Aragen Life Sciences, VectorBuilder, Safe Medical Evaluation, Merck KGaA and Wuxi AppTec.

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