- Companies
- LifeMine Therapeutics
LifeMine Therapeutics Funding, Investors & Competitors
LifeMine Therapeutics has raised $483M across 4 funding rounds, most recently a $188M Series E in August 2026.
Last LifeMine Therapeutics funding round
$188M
Series E · Aug 2026
Cumulative funding LifeMine Therapeutics raised
$483M
across 4 funding rounds
Key investors in LifeMine Therapeutics
GV
ARCH Venture Partners
MRL Ventures Fund
Blue Pool Capital
Invus
Foresite Capital
GSK
WuXi Healthcare Ventures
About LifeMine Therapeutics
LifeMine Therapeutics is a Cambridge-headquartered biotechnology firm harnessing fungal genomics, AI, and synthetic biology for novel drug discovery. Its Avatar-Rx platform screens microbial genomes to identify genetically encoded molecules targeting specific diseases, advancing candidates through chemoinformatics and synthesis for oncology and other therapeutic areas.
Founded
2016
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
LifeMine Therapeutics Funding History
LifeMine Therapeutics has raised a total of $483M across 4 funding rounds.
LifeMine Therapeutics' first fundraising round was a $70M Series A in September 2017. The most recent completed round was a $188M Series E in August 2026.
LifeMine Therapeutics funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Aug 2026 | Series E | Milky Way Investments Group (lead); Gates Industrial; GSK; GV; Invus; LoLa Capital Partners; Bezos Expeditions; RA Capital Management; ARCH Venture Partners | $188M | LifeMine Therapeutics raised $188 million in a Series E financing announced on August 6, 2026, led by Milky Way Investments, with participation from Bezos Expeditions, Gates Frontier, RA Capital Management, and continuing support from GV, GSK, Invus, LoLa Capital Partners, and ARCH Venture Partners. The financing was disclosed as part of a broader $263 million capital raise that also included a previously unannounced $75 million Series D closed in Q4 2025; LifeMine issued convertible preferred stock in the transaction. The capital is intended to accelerate clinical development of LIFE-001, LifeMine’s lead program, a calcineurin activation inhibitor designed for organ transplantation, and to advance the company’s broader transplantation and immunology pipeline. The company plans to launch a Phase 2 kidney transplant study and a Phase 1b islet cell transplant study. LifeMine had previously raised a $175 million Series C in 2022, with ARCH Venture Partners among the continuing backers across multiple rounds. LifeMine Therapeutics is a biotechnology company focused on mining fungal biology and genomes to discover drug-like natural products and apply them to transplantation and immunology. It was founded by Greg Verdine and has drawn support from a recurring syndicate of life-sciences and strategic investors across prior financings. |
| Mar 2022 | Series C | Fidelity (lead); GSK; 3W Partners; GV; Blue Pool Capital; Invus; MRL Ventures Fund; ARCH Venture Partners | $175M | LifeMine Therapeutics, founded in 2017 by Gregory Verdine, Richard Klausner, and WeiQing Zhou, is a biopharmaceutical company based in Cambridge, Massachusetts, with a second site in Gloucester Harbor. The company reinvents drug discovery by mining genetically-encoded small molecules (GEMs) from the biosphere using its proprietary Avatar-Rx platform, which integrates high-throughput microbiology, data science, artificial intelligence, genome engineering, and automation to identify novel GEMs from the fungal biosphere targeting difficult-to-drug proteins, particularly in oncology and immune modulation. On March 23, 2022, LifeMine announced a $175 million Series C financing round led by Fidelity Management & Research Company, with participation from new investors Invus, 3W Partners Capital, and strategic partner GlaxoSmithKline (GSK). Existing investors including GV, Arch Venture Partners, Blue Pool Capital, and MRL Ventures Fund also joined. This brought total funding raised to more than $295 million from leading life science investors. Proceeds from the round are designated to scale the Avatar-Rx platform, advance lead programs targeting genetically validated cancer drivers, and support integration of chemoinformatic-assisted drug optimization, chemical synthesis, and biotransformation capabilities. The financing coincides with a multitarget R&D collaboration with GSK, positioning LifeMine to develop high-impact precision medicines for intractable medical challenges. LifeMine has discovered hundreds of potentially high-impact drug candidates across major disease areas through genomic screening, emphasizing speed, predictability, and scalability in small molecule discovery. CEO Gregory Verdine highlighted the round's role in advancing elusive targets in cancer. |
| Jan 2021 | Series B | Rick Klausner (lead); GV; Blue Pool Capital; Foresite Capital; WuXi Healthcare Ventures; MRL Ventures Fund; ARCH Venture Partners | $50M | LifeMine Therapeutics is a biopharmaceutical company reinventing drug discovery by mining fungal biodiversity and genetically-encoded small molecules from the biosphere to develop mechanistically and structurally novel therapeutics, with an initial focus on precision medicines in oncology and immune modulation. The company leverages a proprietary genomic drug discovery platform that integrates human genetics, genomics, bioinformatics, machine learning, and synthetic biology to identify high-impact drug candidates across major disease areas. Founded in 2017 by Gregory Verdine, Richard Klausner, and WeiQing Zhou, LifeMine is headquartered in Cambridge, MA, with a facility in Gloucester Harbor, MA, and had raised over $120 million from leading life science investors by early 2021. On January 7, 2021, LifeMine announced a $50 million Series B financing led by Rick Klausner and Milky Way Investments, with participation from GV (formerly Google Ventures), WuXi Healthcare Ventures, Foresite Capital, Arch Ventures, Blue Pool Capital, and MRL Ventures Fund. This round building on prior funding including a $55 million Series A in September 2017 led by WuXi Healthcare Ventures. The financing supported progress such as amassing one of the largest fully digitized, genomicized proprietary fungal strain collections and advancing a pipeline of novel drug candidates in oncology, T cell mediated immune disorders, and other areas with high unmet need. |
| Sep 2017 | Series A | GV (lead); WuXi Healthcare Ventures (lead); Boyu Capital; M Ventures; Blue Pool Capital; Alexandria Venture Investments; Foresite Capital; MRL Ventures Fund; ARCH Venture Partners | $70M | LifeMine Therapeutics, founded in 2017 by Gregory Verdine, Ph.D., Richard Klausner, M.D., and WeiQing Zhou, M.B.A., is a biopharmaceutical company focused on reinventing drug discovery by mining fungal biodiversity to develop mechanistically and structurally novel therapeutics, particularly in oncology and T cell mediated immune disorders. The company raised $55 million in its Series A round on September 19, 2017, led by WuXi Healthcare Ventures, with participation from investors including GV (formerly Google Ventures). This followed the company's inception and marked its initial major funding, contributing to a total of over $120 million raised by early 2021. Subsequent rounds included a $50 million Series B in January 2021 led by Rick Klausner and Milky Way Investments, with participation from GV, WuXi Healthcare Ventures, Foresite Capital, Arch Ventures, Blue Pool Capital, and MRL Ventures Fund. The Series B supported advancement of drug discovery programs, acquisition of biodiverse fungal strain collections from Merck and Pfizer, and expansion of its proprietary fungal strain library. By 2021, LifeMine had established sites in Cambridge and Gloucester Harbor, Massachusetts. Later developments included a $175 million Series C round and a $70 million upfront partnership with GlaxoSmithKline for three fungal-derived drug candidates, with GSK contributing to the Series C led by Fidelity Management & Research Company and involving Arch Venture Partners, MRL Ventures Fund, and new investors like 3W Partners Capital and Invus. Funds supported pipeline building, hiring key executives, and expansion to a Basel, Switzerland site for chemistry. |
Who has invested in LifeMine Therapeutics?
19 investors have backed LifeMine Therapeutics across its funding rounds, including GV, ARCH Venture Partners, MRL Ventures Fund, Blue Pool Capital, Invus and Foresite Capital.
Lead investors include Milky Way Investments Group, Fidelity, Rick Klausner, GV and WuXi Healthcare Ventures.
LifeMine Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 4 | Lead | Sep 2017 | ||
| 4 | Participant | Sep 2017 | ||
| 3 | Participant | Sep 2017 | ||
| 3 | Participant | Sep 2017 | ||
| 2 | Participant | Mar 2022 | ||
| 2 | Participant | Mar 2022 | ||
| 2 | Participant | Sep 2017 | ||
| 2 | Lead | Sep 2017 | ||
| 1 | Participant | Aug 2026 | ||
| 1 | Participant | Sep 2017 | ||
| 1 | Participant | Sep 2017 | ||
| 1 | Lead | Mar 2022 | ||
| 1 | Participant | Mar 2022 | ||
This data is available for Pro users. Sign up to see all 19 LifeMine Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialLifeMine Therapeutics Competitors
LifeMine Therapeutics competitors include listed companies like Roche, Johnson & Johnson and Merck KGaA, and private ones like Heyuan Biotechnology, ArsenalBio and Anew Labs.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $77B | $26B | $351B | 4.9x | ||
| Private | - | - | $3B | - | ||
| Private | - | - | $1.9B | - | ||
| Private | - | - | $1.5B | - | ||
| Publicly listed | $94B | $40B | $651B | 6.8x | ||
| Publicly listed | $24B | $5.3B | $66B | 3.1x |
LifeMine Therapeutics Public Comps
LifeMine Therapeutics is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Merck, Roche, Novartis, AstraZeneca, CrowdStrike, SAP and Amgen.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $65B | $28B | 16.5x | 13.1x | 38.7x | 27.0x | |||
| $94B | $40B | 7.2x | 6.8x | 17.0x | 18.3x | |||
| $61B | $17B | 8.7x | 8.1x | 30.6x | 17.6x | |||
| $65B | $28B | 6.3x | 6.2x | 14.7x | 21.0x | |||
| $77B | $26B | 5.0x | 4.9x | 14.6x | 12.4x | |||
| $57B | $22B | 5.5x | 5.5x | 14.2x | 13.3x | |||
| $59B | $19B | 4.8x | 4.5x | 14.6x | 12.7x | |||
| $4.8B | ($12M) | 51.4x | 44.5x | (19816.2x) | 151.0x | |||
This data is available for Pro users. Sign up to see all LifeMine Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about LifeMine Therapeutics
| When was LifeMine Therapeutics founded? | LifeMine Therapeutics was founded in 2016. |
| Where is LifeMine Therapeutics headquartered? | LifeMine Therapeutics is headquartered in United States. |
| Is LifeMine Therapeutics publicly listed? | No, LifeMine Therapeutics is a private, VC-backed company. |
| How much funding has LifeMine Therapeutics raised? | LifeMine Therapeutics has raised $483M across 4 funding rounds. |
| What was LifeMine Therapeutics' last funding round? | LifeMine Therapeutics' last funding round was a $188M Series E in August 2026, led by Milky Way Investments Group. |
| Who are LifeMine Therapeutics' investors? | LifeMine Therapeutics' investors include GV, ARCH Venture Partners, Blue Pool Capital, MRL Ventures Fund, GSK, Invus, Foresite Capital, WuXi Healthcare Ventures, Gates Industrial, Boyu Capital and 9 others. |
| Which companies are comparable to LifeMine Therapeutics? | Companies comparable to LifeMine Therapeutics include Roche, Heyuan Biotechnology, ArsenalBio, Anew Labs, Johnson & Johnson and Merck KGaA. |
See companies similar to LifeMine Therapeutics
Start Your
Free Trial Today
Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.




