LifeMine Therapeutics Funding, Investors & Competitors

LifeMine Therapeutics has raised $483M across 4 funding rounds, most recently a $188M Series E in August 2026.

Last LifeMine Therapeutics funding round

$188M

Series E · Aug 2026

Cumulative funding LifeMine Therapeutics raised

$483M

across 4 funding rounds

Key investors in LifeMine Therapeutics

  • GV
  • ARCH Venture Partners
  • MRL Ventures Fund
  • Blue Pool Capital
  • Invus
  • Foresite Capital
  • GSK
  • WuXi Healthcare Ventures

LifeMine Therapeutics Overview

About LifeMine Therapeutics

LifeMine Therapeutics is a Cambridge-headquartered biotechnology firm harnessing fungal genomics, AI, and synthetic biology for novel drug discovery. Its Avatar-Rx platform screens microbial genomes to identify genetically encoded molecules targeting specific diseases, advancing candidates through chemoinformatics and synthesis for oncology and other therapeutic areas.


Founded

2016

HQ

United StatesUnited States

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

LifeMine Therapeutics Funding History

LifeMine Therapeutics has raised a total of $483M across 4 funding rounds.

LifeMine Therapeutics' first fundraising round was a $70M Series A in September 2017. The most recent completed round was a $188M Series E in August 2026.

LifeMine Therapeutics funding rounds

LifeMine Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
Aug 2026Series EMilky Way Investments Group (lead); Gates Industrial; GSK; GV; Invus; LoLa Capital Partners; Bezos Expeditions; RA Capital Management; ARCH Venture Partners$188MLifeMine Therapeutics raised $188 million in a Series E financing announced on August 6, 2026, led by Milky Way Investments, with participation from Bezos Expeditions, Gates Frontier, RA Capital Management, and continuing support from GV, GSK, Invus, LoLa Capital Partners, and ARCH Venture Partners. The financing was disclosed as part of a broader $263 million capital raise that also included a previously unannounced $75 million Series D closed in Q4 2025; LifeMine issued convertible preferred stock in the transaction. The capital is intended to accelerate clinical development of LIFE-001, LifeMine’s lead program, a calcineurin activation inhibitor designed for organ transplantation, and to advance the company’s broader transplantation and immunology pipeline. The company plans to launch a Phase 2 kidney transplant study and a Phase 1b islet cell transplant study. LifeMine had previously raised a $175 million Series C in 2022, with ARCH Venture Partners among the continuing backers across multiple rounds. LifeMine Therapeutics is a biotechnology company focused on mining fungal biology and genomes to discover drug-like natural products and apply them to transplantation and immunology. It was founded by Greg Verdine and has drawn support from a recurring syndicate of life-sciences and strategic investors across prior financings.
Mar 2022Series CFidelity (lead); GSK; 3W Partners; GV; Blue Pool Capital; Invus; MRL Ventures Fund; ARCH Venture Partners$175MLifeMine Therapeutics, founded in 2017 by Gregory Verdine, Richard Klausner, and WeiQing Zhou, is a biopharmaceutical company based in Cambridge, Massachusetts, with a second site in Gloucester Harbor. The company reinvents drug discovery by mining genetically-encoded small molecules (GEMs) from the biosphere using its proprietary Avatar-Rx platform, which integrates high-throughput microbiology, data science, artificial intelligence, genome engineering, and automation to identify novel GEMs from the fungal biosphere targeting difficult-to-drug proteins, particularly in oncology and immune modulation. On March 23, 2022, LifeMine announced a $175 million Series C financing round led by Fidelity Management & Research Company, with participation from new investors Invus, 3W Partners Capital, and strategic partner GlaxoSmithKline (GSK). Existing investors including GV, Arch Venture Partners, Blue Pool Capital, and MRL Ventures Fund also joined. This brought total funding raised to more than $295 million from leading life science investors. Proceeds from the round are designated to scale the Avatar-Rx platform, advance lead programs targeting genetically validated cancer drivers, and support integration of chemoinformatic-assisted drug optimization, chemical synthesis, and biotransformation capabilities. The financing coincides with a multitarget R&D collaboration with GSK, positioning LifeMine to develop high-impact precision medicines for intractable medical challenges. LifeMine has discovered hundreds of potentially high-impact drug candidates across major disease areas through genomic screening, emphasizing speed, predictability, and scalability in small molecule discovery. CEO Gregory Verdine highlighted the round's role in advancing elusive targets in cancer.
Jan 2021Series BRick Klausner (lead); GV; Blue Pool Capital; Foresite Capital; WuXi Healthcare Ventures; MRL Ventures Fund; ARCH Venture Partners$50MLifeMine Therapeutics is a biopharmaceutical company reinventing drug discovery by mining fungal biodiversity and genetically-encoded small molecules from the biosphere to develop mechanistically and structurally novel therapeutics, with an initial focus on precision medicines in oncology and immune modulation. The company leverages a proprietary genomic drug discovery platform that integrates human genetics, genomics, bioinformatics, machine learning, and synthetic biology to identify high-impact drug candidates across major disease areas. Founded in 2017 by Gregory Verdine, Richard Klausner, and WeiQing Zhou, LifeMine is headquartered in Cambridge, MA, with a facility in Gloucester Harbor, MA, and had raised over $120 million from leading life science investors by early 2021. On January 7, 2021, LifeMine announced a $50 million Series B financing led by Rick Klausner and Milky Way Investments, with participation from GV (formerly Google Ventures), WuXi Healthcare Ventures, Foresite Capital, Arch Ventures, Blue Pool Capital, and MRL Ventures Fund. This round building on prior funding including a $55 million Series A in September 2017 led by WuXi Healthcare Ventures. The financing supported progress such as amassing one of the largest fully digitized, genomicized proprietary fungal strain collections and advancing a pipeline of novel drug candidates in oncology, T cell mediated immune disorders, and other areas with high unmet need.
Sep 2017Series AGV (lead); WuXi Healthcare Ventures (lead); Boyu Capital; M Ventures; Blue Pool Capital; Alexandria Venture Investments; Foresite Capital; MRL Ventures Fund; ARCH Venture Partners$70MLifeMine Therapeutics, founded in 2017 by Gregory Verdine, Ph.D., Richard Klausner, M.D., and WeiQing Zhou, M.B.A., is a biopharmaceutical company focused on reinventing drug discovery by mining fungal biodiversity to develop mechanistically and structurally novel therapeutics, particularly in oncology and T cell mediated immune disorders. The company raised $55 million in its Series A round on September 19, 2017, led by WuXi Healthcare Ventures, with participation from investors including GV (formerly Google Ventures). This followed the company's inception and marked its initial major funding, contributing to a total of over $120 million raised by early 2021. Subsequent rounds included a $50 million Series B in January 2021 led by Rick Klausner and Milky Way Investments, with participation from GV, WuXi Healthcare Ventures, Foresite Capital, Arch Ventures, Blue Pool Capital, and MRL Ventures Fund. The Series B supported advancement of drug discovery programs, acquisition of biodiverse fungal strain collections from Merck and Pfizer, and expansion of its proprietary fungal strain library. By 2021, LifeMine had established sites in Cambridge and Gloucester Harbor, Massachusetts. Later developments included a $175 million Series C round and a $70 million upfront partnership with GlaxoSmithKline for three fungal-derived drug candidates, with GSK contributing to the Series C led by Fidelity Management & Research Company and involving Arch Venture Partners, MRL Ventures Fund, and new investors like 3W Partners Capital and Invus. Funds supported pipeline building, hiring key executives, and expansion to a Basel, Switzerland site for chemistry.

Who has invested in LifeMine Therapeutics?

19 investors have backed LifeMine Therapeutics across its funding rounds, including GV, ARCH Venture Partners, MRL Ventures Fund, Blue Pool Capital, Invus and Foresite Capital.

Lead investors include Milky Way Investments Group, Fidelity, Rick Klausner, GV and WuXi Healthcare Ventures.


LifeMine Therapeutics Investors

Investors in LifeMine Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
GVUnited StatesSan Francisco, CA4LeadSep 2017
ARCH Venture PartnersUnited StatesChicago, IL4ParticipantSep 2017
Blue Pool CapitalHong KongHong Kong3ParticipantSep 2017
MRL Ventures FundUnited StatesUnited States3ParticipantSep 2017
GSKUnited KingdomLondon2ParticipantMar 2022
InvusUnited StatesNew York City, NY2ParticipantMar 2022
Foresite CapitalUnited StatesSan Francisco, CA2ParticipantSep 2017
WuXi Healthcare VenturesUnited StatesUnited States2LeadSep 2017
Gates IndustrialUnited StatesDenver, CO1ParticipantAug 2026
Boyu CapitalChinaBeijing1ParticipantSep 2017
M VenturesNetherlandsAmsterdam1ParticipantSep 2017
FidelityUnited StatesBoston, MA1LeadMar 2022
3W PartnersUnited StatesUnited States1ParticipantMar 2022

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LifeMine Therapeutics Competitors

LifeMine Therapeutics competitors include listed companies like Roche, Johnson & Johnson and Merck KGaA, and private ones like Heyuan Biotechnology, ArsenalBio and Anew Labs.

Public and private companies comparable to LifeMine Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
RocheSwitzerlandSwitzerlandPublicly listed$77B$26B$351B4.9x
Heyuan BiotechnologyChinaShanghaiPrivate--$3B-
ArsenalBioUnited StatesUnited StatesPrivate--$1.9B-
Anew LabsChinaShanghaiPrivate--$1.5B-
Johnson & JohnsonUnited StatesUnited StatesPublicly listed$94B$40B$651B6.8x
Merck KGaAGermanyGermanyPublicly listed$24B$5.3B$66B3.1x

LifeMine Therapeutics Public Comps

LifeMine Therapeutics is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Merck, Roche, Novartis, AstraZeneca, CrowdStrike, SAP and Amgen.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Eli Lilly$65B$28B16.5x13.1x38.7x27.0x
Johnson & Johnson$94B$40B7.2x6.8x17.0x18.3x
AbbVie$61B$17B8.7x8.1x30.6x17.6x
Merck$65B$28B6.3x6.2x14.7x21.0x
Roche$77B$26B5.0x4.9x14.6x12.4x
Novartis$57B$22B5.5x5.5x14.2x13.3x
AstraZeneca$59B$19B4.8x4.5x14.6x12.7x
CrowdStrike$4.8B($12M)51.4x44.5x(19816.2x)151.0x

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Common questions about LifeMine Therapeutics

When was LifeMine Therapeutics founded?LifeMine Therapeutics was founded in 2016.
Where is LifeMine Therapeutics headquartered?LifeMine Therapeutics is headquartered in United States.
Is LifeMine Therapeutics publicly listed?No, LifeMine Therapeutics is a private, VC-backed company.
How much funding has LifeMine Therapeutics raised?LifeMine Therapeutics has raised $483M across 4 funding rounds.
What was LifeMine Therapeutics' last funding round?LifeMine Therapeutics' last funding round was a $188M Series E in August 2026, led by Milky Way Investments Group.
Who are LifeMine Therapeutics' investors?LifeMine Therapeutics' investors include GV, ARCH Venture Partners, Blue Pool Capital, MRL Ventures Fund, GSK, Invus, Foresite Capital, WuXi Healthcare Ventures, Gates Industrial, Boyu Capital and 9 others.
Which companies are comparable to LifeMine Therapeutics?Companies comparable to LifeMine Therapeutics include Roche, Heyuan Biotechnology, ArsenalBio, Anew Labs, Johnson & Johnson and Merck KGaA.

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