Crinetics Pharmaceuticals Acquisition, Valuation & Financials

Haisco Pharmaceutical Group Co Ltd is a pharmaceutical company based in China. It is mainly engaged in the research, development, manufacture, and sale of drugs for liver disease. Its product portfolio includes parenteral nutrition drugs, antibiotics, anesthetic agents, digestive system drugs and tumour adjuvant drug series. The company's products are being used in first rank hospitals in China.

Vaxcyte Inc is a clinical-stage vaccine company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. It uses the XpressCF cell-free protein synthesis platform to develop potentially superior and novel conjugate and protein vaccine candidates for adult and pediatric indications. The company's product pipeline includes: VAX-31, VAX-24, and VAX-XL PCV vaccine candidates; VAX-A1, a Novel Group A Strep Vaccine; and VAX-GI, a Novel Shigella Vaccine, among others, in their different stages of development.

Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Akeso Inc is an investment holding company. The Company's subsidiaries were involved in research and development, production, and commercialization of biopharmaceutical products. The company currently has a pipeline of over 30 drugs for the treatment of diseases like cancers, autoimmune diseases, inflammation, and metabolic diseases, 17 of which have entered the clinical stage, including two first-in-class bi-specific antibody drugs (PD-1/CTLA-4 and PD-1/VEGF). The majority of the company's revenue is earned in Mainland China, and also has its presence in USA and Other regions.

Alteogen is a South Korean biotechnology company headquartered in Daejeon and listed on the KOSDAQ market, founded in 2008. It researches and develops next-generation biobetters and biosimilars and licenses proprietary platform technologies, including the Hybrozyme subcutaneous formulation platform based on ALT-B4 (berahyaluronidase alfa), the NexP long-acting fusion technology and the NexMab antibody-drug conjugate technology. Its main customers are global pharmaceutical companies, and it has signed licensing agreements with ten drugmakers including MSD, AstraZeneca, Sanofi and Novartis. Revenue comes mainly from upfront payments, milestone payments and royalties, including royalties on sales of subcutaneous Keytruda that uses ALT-B4, with additional income from supplying the material to MSD through an outside contract manufacturer. In October 2026 the company agreed to issue KRW 200 billion of preferred shares to a vehicle of the National Growth Fund and Skylake Equity Partners to build a production plant in Daejeon and acquire new products.

Lupin Ltd is a specialty and generic drug manufacturing company. The company produces, develops, and markets branded and generic formulations, biotechnology products, and active pharmaceutical ingredients (APIs) globally. It has a presence in the Cardiovascular, Diabetology, Asthma, Pediatrics, Central Nervous System, GastroIntestinal, and other drug therapy segments. The operations of the company are limited to the segments, namely pharmaceuticals which derives key revenue, and others. It also maintains a pipeline in high-barrier markets such as Inhalation, Biosimilars, and Complex Injectables. The vast majority of the company's sales are generated in the United States, followed by India, and other countries.

Sichuan Kelun Pharmaceutical Co Ltd is a China-based pharmaceutical company focused on the manufacturing of infusion products, antibiotics, and various medical devices. The company operates its businesses through three segments. The Twinings segment focuses on producing pharmaceutical intermediates. The Botai segment is dedicated to the research, development, manufacturing, and commercialization of medicines. The Other Business segment covers activities such as the development and production of large-volume injections, along with the research, manufacturing, and sales of additional pharmaceutical products and related businesses.

Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, and premature mortality. The company's medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor agonist designed to target key underlying causes of MASH.

BioMarin is a global biotechnology company focused on developing and commercializing therapies for rare genetic diseases. BioMarin specializes in enzyme replacement therapies, gene therapies, and other advanced treatments designed to address complex genetic disorders. The company has eight approved therapies for conditions including achondroplasia, phenylketonuria, hemophilia, and mucopolysaccharidosis. BioMarin has an expanding, yet relatively early-stage, pipeline of treatments in development across skeletal conditions and enzyme therapies.

TG Therapeutics Inc is a fully integrated, commercial-stage biotechnology company focused on acquiring, developing, and commercializing novel treatments for B-cell diseases. In addition to a research pipeline, TG Therapeutics has received approval from the U.S. Food and Drug Administration (FDA) for BRIUMVI (ublituximab-xiiy) to treat adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, as well as approval from several regulatory agencies outside of the U.S. for BRIUMVI to treat adult patients with RMS who have active disease defined by clinical or imaging features.

ImmunityBio Inc is a biotechnology company focused on developing and commercializing next-generation immunotherapies designed to activate the patient's immune system and provide durable protection against cancer and infectious diseases. Its approach harnesses both the adaptive and innate immune systems with the Cancer BioShield platform. The platform is built around the proprietary IL-15 superagonist ANKTIVA (nogapendekin alfa inbakicept) and is supported by a portfolio that includes adenovirus-vectored vaccines, NK-cell therapies, and additional immunomodulators. The company operates in the United States and Europe, with the majority of its revenue coming from the United States.

Aurobindo Pharma Ltd is a specialty and generic drug manufacturing company. It is principally engaged in the manufacturing and marketing of active pharmaceutical ingredients, generic pharmaceuticals, and related services. Its formulations target key therapeutic areas, including Central Nervous System (CNS), Antibiotics, Anti-diabetics, Cardiovascular, Anti-retroviral, Gastroenterology, Oncology, and Dermatology. The operating and reportable segments of the company are; India, the United States of America, Europe, and the Rest of the World. The company generates a majority of its revenue from its business in the United States of America.

Mankind Pharma Ltd is engaged in developing, manufacturing, and marketing a diverse range of pharmaceutical formulations across various acute and chronic therapeutic areas, as well as several consumer healthcare products. It operates at the intersection of Indian pharmaceutical formulations and consumer healthcare sectors providing products at affordable prices and has an established track record of building and scaling brands in-house. The company's brands include Manforce, Prega News, Gas-O-Fast, AcneStar and HealthOK. Geographically, the company derives a majority of its revenue from the sale of pharmaceutical products in India and the rest from its customers located outside India.

Krystal Biotech Inc is an integrated, commercial-stage biotechnology company focused on the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs. The company uses its patented HSV-1-based gene therapy platform to create vectors that deliver therapeutic transgenes to target cells. It possesses exclusive rights to develop, manufacture, and commercialize VYJUVEK internationally. The company operates as one operating segment focused on pharmaceutical products and manufactures, markets, and sells VYJUVEK in the United States and markets and sells VYJUVEK in the European Union, and Japan.

Intas Pharmaceuticals is an Indian multinational pharmaceutical company headquartered in Ahmedabad, Gujarat, that develops, manufactures and markets generic and branded formulations, active ingredients and biosimilars. It was founded by Hasmukh Chudgar in 1977 and incorporated in 1985, and it is controlled by the Chudgar family, with Temasek and ChrysCapital as minority investors and the Abu Dhabi Investment Authority joining in 2022. It operates 22 manufacturing plants, 17 of them in India, and employs more than 25,000 people. Its Accord Healthcare subsidiary, which bought the Actavis UK and Ireland generics business in FY2017, gives it a large European business: in FY2022 Europe contributed about 39% of consolidated turnover, India 33% and the United States about 16%. ICRA reported consolidated operating income of Rs 18,416 crore for FY2022 and Rs 20,086 crore for FY2023, and ranked Intas seventh in the Indian pharmaceutical market in FY2022. Revenue comes from product sales, with specialty medicines such as oncology and biosimilars an increasing focus.

Biosplice Therapeutics is a clinical-stage biotechnology firm headquartered in San Diego, California. The company develops small-molecule modulators of splicing factors to treat degenerative diseases, fibrosis, and cancers, with lead candidates in phase II trials for osteoarthritis and dry age-related macular degeneration.

Biocon Biologics is an Indian biosimilars company headquartered in Bengaluru and a subsidiary of the listed group Biocon Limited. It develops, manufactures and sells biosimilar medicines in diabetes, oncology and immunology, including insulin, trastuzumab and pegfilgrastim products, in the United States, Europe, Japan, Canada, Australia and emerging markets. The business grew out of Biocon's insulin work that began in the early 2000s and was set up as a separate unit before outside investors including True North, Tata Capital Growth Fund, Goldman Sachs, ADQ and Serum Institute Life Sciences bought minority stakes between 2020 and 2023. In 2022 it acquired the global biosimilars business of its former partner Viatris, which gave it its own commercial network in developed markets. Revenue crossed USD 1 billion in the year to March 2024. In December 2025 Biocon Limited announced a plan to absorb the company and buy out the remaining minority holders through a share swap.

LEO Pharma is a Ballerup-headquartered pharmaceutical company focused on medical dermatology. It develops therapies for psoriasis, atopic dermatitis, actinic keratosis, and other skin ailments. Key products include calcipotriol/betamethasone dipropionate combinations, IL-17 inhibitors, and topical treatments. Research occurs at facilities in Denmark, the United States, the United Kingdom, and Ireland. The firm distributes in over 100 countries through direct subsidiaries and licensing agreements. Founded in 1908.