![Adheris Health logo](data:image/svg+xml,<svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 20 20"><rect fill="%23e5e7eb" width="20" height="20" rx="4"/></svg>)
September 2026
Largest Digital Therapeutics Public Companies
Benchmark revenue and EBITDA valuation multiples for public comps like
Compass Pathways, Alignment Healthcare, Helus Pharma, Sphere and Nyxoah.
 | Compass Pathways PLC is a mental health care company dedicated to accelerating patient access to evidence-based innovation in mental health. The company is motivated by the need to find ways to help and empower people suffering with mental health challenges who are not helped by existing therapies and are pioneering the development of a new model of psilocybin therapy, in which psilocybin is administered in conjunction with psychological support. Its focus is on treatment-resistant depression, or TRD, a subset of major depressive disorder, or MDD, comprising patients who are inadequately served by the treatment paradigm. It has developed a proprietary, high-purity polymorphic crystalline formulation of psilocybin, COMP360. | $15 | +165% | $2.1B | $1.7B | - | (5.9x) | ||
 | Alignment Healthcare Inc is a next-generation, consumer-centric platform that is revolutionizing the healthcare experience for seniors through Medicare Advantage plans. These plans are marketed and sold direct-to-consumer, allowing seniors to select the manner in which customers receive healthcare coverage and services on an annual basis. The company combines a technology platform and clinical model for more effective health outcomes. | $8 | -52% | $1.7B | $1.4B | 0.3x | 30.0x | ||
 | Helus Pharma Inc is a clinical-stage pharmaceutical company developing proprietary novel serotonergic agonists (NSAs), which are synthetic molecules designed to activate serotonin pathways associated with neuroplasticity. These compounds are being investigated for potential use in the treatment of depression, anxiety, and other mental health conditions, areas where there is an unmet medical need. It aims to provide treatments designed for mental health disorders. The company is currently developing HLP003, a proprietary NSA, in Phase 3 clinical development for the adjunctive treatment of substantial depressive disorder. It operates in Canada, the United States, the United Kingdom, and Ireland. | $13 | -- | $917M | $748M | - | (4.9x) | ||
 | Sphere Corp Formerly Life Semantics Corp is engaged in the development and supply of innovative healthcare solutions such as providing a technology platform for digital transformation in the healthcare field and non-face-to-face medical and digital treatment devices. | $17 | +135% | $867M | $1B | 15.2x | 165.8x | ||
 | Nyxoah SA is a health-technology company focused on the development and commercialization of solutions and services to treat sleep-disordered breathing conditions. The company's solution platform is based on the Genio system, a CE-Mark validated, user-centered, bilateral neurostimulation therapy to treat moderate to severe Obstructive Sleep Apnea (OSA), the common sleep disordered breathing condition that is associated with increased mortality risk and comorbidities including cardiovascular diseases, depression and stroke. | $2 | -67% | $153M | $101M | 8.8x | (1.0x) | ||
| Oneview Healthcare PLC provides patient engagement and clinical workflow technology solutions to healthcare facilities. It serves hospitals and healthcare systems, academic medical centers, and pediatric hospitals. Oneview Healthcare’s Care Experience Platform (CXP) provides a unified set of digital tools in a single bedside solution and connects patients, families, and care teams with services, education, and information during hospital stays. | $0 | -32% | $100M | $99M | 7.2x | (8.2x) | ||
| Kooth PLC is a digital mental health provider to the NHS for children and young people by providing a broad range of therapeutic tools and interventions. The company's online platform provides Self-help tools and content, Community for Peer-to-Peer Support and Professional Counselling. It provides individuals with free access to mental health support, funded by healthcare systems, insurers, businesses or charities. The company's operations take place in the UK and the United States. | $3 | +32% | $91M | $62M | 0.7x | 4.7x | ||
| Saluda Medical Inc is a commercial-stage medical device company focused on developing treatments for chronic neurological conditions using its novel neuromodulation platform. The company’s first product, the Evoke System, is indicated as an aid in the management of chronic intractable pain of the trunk and/or limbs, including unilateral or bilateral pain associated with failed back surgery syndrome, intractable low back pain, and leg pain, and is designed to treat chronic neuropathic pain by providing spinal cord stimulation (SCS) therapy. | $0 | -- | $72M | - | - | - | ||
| DarioHealth Corp is a digital therapeutics (DTx) company delivering personalized evidence-based interventions that are driven by precision data analytics, software, and personalized coaching. Its cross-functional team operates at the intersection of life sciences, behavioral science, and software technology to deliver seamlessly integrated and engaging digital therapeutics interventions. Also platform and suite of solutions deliver personalized and dynamic interventions driven by data analytics and one-on-one coaching for diabetes, hypertension, weight management, musculoskeletal pain, and behavioral health. | $7 | -51% | $71M | $89M | 4.0x | (2.4x) | ||
 | Welby Inc offers patients and their families digital tools helping medical treatment and prevention of the progression of disease. The company co-develops and co-provides digital services with pharmaceuticals, medical device companies, governments, along with patients and healthcare professionals. | $2 | -9% | $16M | $17M | 4.2x | (5.3x) | ||
| Physitrack PLC is a digital healthcare provider, focused on physiotherapy and musculoskeletal care market. The company operates in two business lines namely Lifecare and Wellness. The Lifecare segment is the provision of Lifecare platforms tailored to physiotherapy being made up of the Physitrack PLC, Physiotools OY and Mobilus Digital Rehab AB Physiotools businesses. The Wellness segment relates to the provision of Wellness services including digital platforms to both corporates and individuals. Geographically, the company has its presence in United Kingdom, Europe, North America and Rest of World. | $1 | -56% | $15M | $19M | 1.2x | (8.4x) | ||
 | iXensor Co Ltd is a Taiwan based company involved in research and development, manufacturing and sales of medical equipment. Its PixoTest technology utilizes the lighting and image sensing module of the smartphone or mobile device to detect the color change reaction on the biochemical test strip. This enables the users to monitor their conditions of diabetes, cardiovascular diseases, women health problems, or infectious diseases. | $0 | -28% | $7M | $8M | 8.9x | (6.0x) | ||
 | Adheris Health Ltd is an E-healthcare software development company that provides pharmacy-driven patient engagement solutions that include personalised patient experiences to help simplify the patient medication journey. The group is leveraging THRIV, a cloud-based, AI-enabled platform. Its solutions empower the pharmacy of the future through improved pharmacy workflow and patient engagement solutions. | $0 | -- | $6M | - | - | - | ||
| TALI Digital Ltd engaged in research and development, for commercialization, of medical technology projects. It is a digital health company delivering diagnostic and therapeutic solutions to improve cognitive function and behavior. | $0 | -3% | $3M | $3M | 16.6x | (1.7x) | ||
| Tivic Health Systems Inc is a health technology company focused on developing and commercializing non-invasive bioelectronic medicine. The company's platform-based technology activates the body’s own healing mechanisms and can be programmed to treat various disease conditions. company's products provide a natural alternative to the standard synthetic chemical methods used by the pharmaceutical industry. ClearUP Sinus Relief, is a first commercial product of the company which is a patented handled device that uses ultra-low current electrical waves to relieve sinus pain and congestion symptoms that are prevalent in nasal allergies, sinus infections, chronic sinusitis, cold and flu and other disease conditions. | $2 | -- | $2M | $25M | - | (3.2x) | ||
| AMJ Global Technology is a USA-based company which is focusing on the intersection of technology and wholistic technology-based health treatments, with the intention to provide services to formulate a treatment model to meet the needs of professional athletes that suffer from PTSD and the early onset of dementia and Alzheimer’s. The Company is currently evaluating operations in the wholistic health industry. The Company has not generated any revenue. | $0 | -99% | $1M | $1M | ||||
| Delic Holdings Corp is a media, e-commerce, and event company that operates in the field of psychedelic wellness. The company spreads awareness regarding the growing space of psychedelic therapies used as possible treatments for PTSD, anxiety, depression, and other mental health conditions. The business has four distinct segments: The Delic (e-commerce website and blog), Reality Sandwich (online education platform), Meet Delic (bi-annual event), and Delic Radio (podcast), each of which is dedicated to public education and de-stigmatizing the psychedelic conversation for a mainstream audience. | $0 | -- | $9K | $9K | ||||
| Median | $2 | -30% | $71M | $62M | 5.7x | (3.2x) |
Financial data powered by FactSet and Morningstar. Valuation multiples as of current fiscal year. For more data, start your free trial here.
Recent Insights
Start Your
Free Trial Today
Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.