Mission Bio Funding, Investors & Competitors

Mission Bio has raised $110M across 3 funding rounds, most recently a $70M Series C in August 2020.

Last Mission Bio funding round

$70M

Series C · Aug 2020

Cumulative funding Mission Bio raised

$110M

across 3 funding rounds

Key investors in Mission Bio

  • Mayfield Fund
  • Cota Capital
  • Sand Hill Angels
  • Novo Holdings
  • StartX (Stanford-StartX Fund)
  • Tech Coast Angels
  • Keiretsu Forum
  • Labcorp

Mission Bio Overview

About Mission Bio

Mission Bio is a South San Francisco-headquartered genomics company founded in 2014 offering the Tapestri platform for single-cell DNA sequencing in cancer research. The system analyzes SNVs, CNVs, and protein markers from individual cells, enabling studies of tumor heterogeneity in leukemia and solid tumors. Adopted by labs at MD Anderson Cancer Center and Dana-Farber, it processes up to 10,000 cells per sample with 99% accuracy.


Founded

2012

HQ

United StatesSan Francisco, CA

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Mission Bio Funding History

Mission Bio has raised a total of $110M across 3 funding rounds.

Mission Bio's first fundraising round was a $10M Series A in October 2017. The most recent completed round was a $70M Series C in August 2020.

Mission Bio funding rounds

Mission Bio funding rounds
DateStageInvestorsRaisedDeal Summary
Aug 2020Series CNovo Holdings (lead); Seabed VC; Soleus Capital; Agilent Ventures; Cota Capital; Mayfield Fund$70MMission Bio, Inc., based in South San Francisco, California, is a pioneer in high-throughput single-cell DNA and multi-omics analysis, offering the Tapestri Platform that simultaneously detects DNA and protein changes to provide insights into mutations driving disease, particularly in cancer research. The platform supports biomarker discovery, monitoring therapy resistance and response, and accelerating clinical trials for novel cancer treatments, cell, and gene therapies. On August 13, 2020, Mission Bio announced a $70 million Series C funding round led by Novo Growth, the growth equity arm of Novo Holdings, with participation from new investor Soleus Capital and existing investors Mayfield, Cota Capital, and Agilent Ventures. This brought the company's total funding to more than $120 million across multiple rounds. Robert Ghenchev, Senior Partner and Head of Novo Growth, joined the board as part of the investment. The funds are designated to scale the Tapestri Platform, expand its application in clinical trials for cancer therapies, and enhance characterization for cell and gene therapy development, aiming to improve precision therapy outcomes. CEO and Co-founder Charlie Silver highlighted the platform's role in eliminating cancer by accessing multiple cellular profile layers.
Dec 2018Series BAgilent; Sand Hill Angels; Labcorp; Cota Capital; Mayfield Fund$30M-
Oct 2017Series AMayfield Fund (lead); Life Science Angels; Keiretsu Forum; Sand Hill Angels; Cota Capital; StartX (Stanford-StartX Fund); Tech Coast Angels$10MMission Bio is a single-cell genomics company founded in 2012 as a spin-out of research conducted at UCSF. The company developed the Tapestri platform, a precision genomics solution capable of analyzing DNA and protein changes at the single-cell level with throughput up to 10,000 cells, addressing industry needs in clinical trial optimization and precision medicine applications. In October 2017, Mission Bio completed a $10 million Series A financing round led by Mayfield Fund, with participation from other investors including Sand Hill Angels and Tech Coast Angels. The round supported the commercial launch of the Tapestri platform, which subsequently gained adoption across leading cancer research centers including UCSF, Stanford, and Memorial Sloan Kettering Cancer Center, as well as major biopharma companies including LabCorp and Agios. The company continued its growth trajectory, raising a $30 million Series B in December 2018 and a $70 million Series C in August 2020, bringing total funding to over $120 million by that date.

Who has invested in Mission Bio?

13 investors have backed Mission Bio across its funding rounds, including Mayfield Fund, Cota Capital, Sand Hill Angels, Novo Holdings, StartX (Stanford-StartX Fund) and Tech Coast Angels.

Lead investors include Novo Holdings and Mayfield Fund.


Mission Bio Investors

Investors in Mission Bio by funding rounds participated
InvestorHQRoundsRoleFirst check
Cota CapitalUnited StatesSan Francisco, CA3ParticipantOct 2017
Mayfield FundUnited StatesUnited States3LeadOct 2017
Sand Hill AngelsUnited StatesSan Francisco, CA2ParticipantOct 2017
Life Science AngelsUnited StatesSan Francisco, CA1ParticipantOct 2017
Novo HoldingsDenmarkCopenhagen1LeadAug 2020
Seabed VCUnited StatesSan Jose, CA1ParticipantAug 2020
Soleus CapitalUnited StatesGreenwich, CT1ParticipantAug 2020
Keiretsu ForumUnited StatesSan Francisco, CA1ParticipantOct 2017
Agilent VenturesUnited StatesSan Francisco, CA1ParticipantAug 2020
AgilentUnited StatesUnited States1ParticipantDec 2018
LabcorpUnited StatesUnited States1ParticipantDec 2018

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Mission Bio Competitors

Mission Bio competitors include listed companies like Illumina, 10x Genomics, BillionToOne and Personalis, and private ones like BGI Group and Sangon Biotech.

Public and private companies comparable to Mission Bio
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
IlluminaUnited StatesUnited StatesPublicly listed$4.3B$1.4B$36B8.3x
10x GenomicsUnited StatesUnited StatesPublicly listed$643M($16M)$10B15.2x
BillionToOneUnited StatesUnited StatesPublicly listed$305M$12M$5B11.1x
PersonalisUnited StatesUnited StatesPublicly listed$70M($78M)$1.8B20.3x
BGI GroupChinaShenzhenPrivate--$1.6B-
Sangon BiotechChinaShanghaiPrivate$102M-$1.4B13.7x

Mission Bio Public Comps

Mission Bio is still privately-owned, but its public comps include Roche, Merck KGaA, Natera, Illumina, Guardant Health, Sartorius, Bio-Techne, Twist Bioscience, 10x Genomics and Demant.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Roche$77B$26B4.9x4.9x14.5x12.2x
Merck KGaA$24B$5.3B3.1x3.1x14.2x10.7x
Natera$2.3B($266M)22.7x19.1x(196.6x)(264.1x)
Illumina$4.3B$1.4B8.6x8.3x26.5x29.3x
Guardant Health$982M($408M)25.2x19.8x(60.6x)(127.0x)
Sartorius$4.1B$1.1B5.7x5.5x22.1x18.5x
Bio-Techne$1.2B$343M9.4x9.3x33.1x26.3x
Twist Bioscience$377M($63M)29.2x24.2x(173.3x)(340.6x)

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Common questions about Mission Bio

When was Mission Bio founded?Mission Bio was founded in 2012.
Where is Mission Bio headquartered?Mission Bio is headquartered in San Francisco, CA, United States.
Is Mission Bio publicly listed?No, Mission Bio is a private, VC-backed company.
How much funding has Mission Bio raised?Mission Bio has raised $110M across 3 funding rounds.
What was Mission Bio's last funding round?Mission Bio's last funding round was a $70M Series C in August 2020, led by Novo Holdings.
Who are Mission Bio's investors?Mission Bio's investors include Cota Capital, Mayfield Fund, Sand Hill Angels, Life Science Angels, Novo Holdings, Seabed VC, Soleus Capital, Keiretsu Forum, Agilent Ventures, Agilent and 3 others.
Which companies are comparable to Mission Bio?Companies comparable to Mission Bio include Illumina, 10x Genomics, BillionToOne, Personalis, BGI Group and Sangon Biotech.

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