Geneoscopy Valuation, Funding & Investors

Geneoscopy is valued at $630M as of November 2021.

Last Geneoscopy valuation

$630M

Series B · Nov 2021

Last Geneoscopy funding round

$105M

Series C · Jan 2025

Cumulative funding Geneoscopy raised

$218M

across 4 funding rounds

Key investors in Geneoscopy

  • Cultivation Capital
  • Morningside
  • Labcorp
  • Lightchain
  • NT Investments
  • Missouri Technology Corporation

Geneoscopy Overview

About Geneoscopy

Geneoscopy is a St. Louis-based diagnostics company that offers non-invasive stool RNA tests for colorectal cancer screening using computational biology. Its ColoSense assay detects gene expression changes in human RNA extracted from stool, achieving 92 percent sensitivity for CRC and 90 percent for advanced adenomas in pivotal trials. Geneoscopy expands its platform to other gastrointestinal diseases including IBD and pancreatic cancer screening.


Founded

2015

HQ

United StatesSaint Louis, MO

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Valuation

$630M (Nov 2021)

Geneoscopy Valuation

Geneoscopy is currently valued at $630M, based on its Series B in November 2021.

The $105M round was led by Lightchain and NT Investments, with participation from BioGenerator, Innovatus Capital Partners, Labcorp, Cultivation Capital and Morningside.

Geneoscopy valuation by funding round

Geneoscopy valuation by funding round
DateStageValuation
Nov 2021Series B$630M

Geneoscopy Funding History

Geneoscopy has raised a total of $218M across 4 funding rounds.

Geneoscopy's first fundraising round was a $1M seed round in April 2018. The most recent completed round was a $105M Series C in January 2025.

Geneoscopy funding rounds

Geneoscopy funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Jan 2025Series CBio-Rad Laboratories (lead); SINC Fund; Lightchain Capital; Tri Locum Partners; Mercy; Labcorp; Granger Management LLC; NT Investments; Varia Ventures; Petrichor Healthcare Capital Management; Morningside$105M-Geneoscopy, Inc., a St. Louis-based life sciences company founded in 2015, develops non-invasive diagnostic tests for gastrointestinal health, focusing on colorectal cancer screening and inflammatory bowel disease. The company recently received FDA approval for ColoSense, an at-home stool-based test for colorectal cancer detection in individuals 45 and older, utilizing RNA biomarkers analyzed via Bio-Rad's QXDx ddPCR platform for high sensitivity in detecting cancer and advanced adenomas. Geneoscopy has raised over $100 million in prior financing and employs about 54 people, primarily at its Maryland Heights headquarters. On January 8, 2025, Geneoscopy closed a $105 million Series C funding round led by Bio-Rad Laboratories (NYSE: BIO, BIO.B), with participation from Petrichor Healthcare Capital Management, Labcorp (NYSE: LH), Morningside Ventures, Lightchain Capital, NT Investments, Granger Management LLC, Mercy Health, Tri Locum Partners, SINC Fund, Varia Ventures, and others. The investment supports the commercial launch of ColoSense in partnership with Labcorp for broad U.S. healthcare provider access and continued development of its pipeline for inflammatory bowel disease diagnostics and other GI conditions, including treatment selection and therapy monitoring in collaboration with universities and biopharma firms. Bio-Rad, a $2.7 billion revenue company in 2023 with 7,700 employees, emphasized the synergy with its Droplet Digital PCR technology for oncology applications. Geneoscopy's CEO Andrew Barnell highlighted the funding as validation of its RNA stool analysis platform's potential to meet unmet needs in GI health. The company presented updates on commercialization plans at the 43rd Annual J.P. Morgan Healthcare Conference on January 16, 2025.
Nov 2021Series BLightchain (lead); NT Investments (lead); BioGenerator; Innovatus Capital Partners; Labcorp; Cultivation Capital; Morningside$105M$630MGeneoscopy is a US-based clinical-stage biotech company founded in 2015, developing non-invasive colorectal cancer screening technology that analyzes RNA from patient stool samples to detect pre-cancerous lesions. The company received breakthrough device designation from the FDA in January 2020 and was advancing a pivotal 10,000-patient clinical trial for its multifactor RNA test at the time of the round. It previously raised a $6.9M Series A in October 2019 co-led by Cultivation Capital and NT Investments with Lightchain Capital participation, and $1M in 2018 from Missouri Technology Corp and Billiken Angel Network. On approximately November 16, 2021, Geneoscopy closed a Series B round of $105M in equity and debt, co-led by Lightchain Capital and NT Investments, with participation from BioGenerator, Cultivation Capital, Innovatus Capital Partners, Labcorp, and Morningside Ventures. Proceeds funded commercialization of the screening platform, expansion of the product pipeline, and ongoing clinical work toward launch. LXL Capital (Lightchain) estimated the company's valuation at $630M to $945M for this round. The financing positioned Geneoscopy among St. Louis-area cancer diagnostic startups raising over $100M in 2021, amid momentum from its trial and plans to address broader gastrointestinal health needs. Later funding included a debt round on the same date and a $105M Series C in January 2025 with additional investors like Bio-Rad Laboratories and Mercy Health.
Oct 2019Series ACultivation Capital (lead); Lightchain; Rodger Riney$7M-Geneoscopy raised $6.9 million in a Series A funding round on October 2, 2019, co-led by Cultivation Capital and NT Investments with participation from Lightchain Capital. The St. Louis-based company develops noninvasive diagnostic tests for gastrointestinal health, focusing on colorectal cancer screening using RNA analysis from stool samples. This round followed a $1 million investment from Missouri Technology Corp and Billiken Angel Network in 2018. Proceeds supported advancement of Geneoscopy's screening platform. The company later received FDA breakthrough device designation in January 2020 and progressed toward commercialization of tests like ColoSense for colorectal cancer screening in adults 45 and older.
Apr 2018SeedMissouri Technology Corporation; Billiken Angels Network$1M--

Who has invested in Geneoscopy?

18 investors have backed Geneoscopy across its funding rounds, including Cultivation Capital, Morningside, Labcorp, Lightchain, NT Investments and Missouri Technology Corporation.

Lead investors include Bio-Rad Laboratories, Lightchain, NT Investments and Cultivation Capital.


Geneoscopy Investors

Investors in Geneoscopy by funding rounds participated
InvestorHQRoundsRoleFirst check
Lightchain--2LeadOct 2019
LabcorpUnited StatesUnited States2ParticipantNov 2021
NT InvestmentsUnited StatesChicago, IL2LeadNov 2021
Cultivation CapitalUnited StatesSt Louis, MO2LeadOct 2019
MorningsideUnited StatesBoston, MA2ParticipantNov 2021
BioGeneratorUnited StatesSt Louis, MO1ParticipantNov 2021
SINC Fund--1ParticipantJan 2025
Lightchain CapitalUnited StatesSt Louis, MO1ParticipantJan 2025
Innovatus Capital PartnersUnited StatesNew York City, NY1ParticipantNov 2021
Tri Locum PartnersUnited StatesNew York City, NY1ParticipantJan 2025
Rodger Riney--1ParticipantOct 2019
MercyUnited StatesSaint Louis, MO1ParticipantJan 2025
Missouri Technology CorporationUnited StatesJefferson City, MO1ParticipantApr 2018

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Geneoscopy Competitors

Geneoscopy competitors include listed companies like Castle Biosciences and Atrys Health, and private ones like MedGenome, Everly Health, uBiome and Genome Medical.

Public and private companies comparable to Geneoscopy
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
MedGenomeIndiaBangalorePrivate--$950M-
Castle BiosciencesUnited StatesUnited StatesPublicly listed$344M($429K)$1.1B2.5x
Everly HealthUnited StatesUnited StatesPrivate--$1.3B-
uBiomeUnited StatesSan Francisco, CAPrivate--$298M-
Atrys HealthSpainSpainPublicly listed$162M($12M)$245M2.1x
Genome MedicalUnited StatesSan Francisco, CAPrivate--$230M-

Geneoscopy Public Comps

Geneoscopy is still privately-owned, but its public comps include Scribe Therapeutics, Fulgent Genetics, Genfit, SOPHiA Genetics, Sphere, Pacific Biosciences, Prenetics Global, Myriad Genetics, Eckert & Ziegler and Novogene.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Scribe Therapeutics$51M($21M)14.2x-(34.0x)-
Fulgent Genetics$323M($77M)1.1x1.1x(4.5x)(6.2x)
Genfit$75M($98M)9.9x7.9x(7.7x)52.1x
SOPHiA Genetics$77M($65M)8.8x7.5x(10.4x)(18.8x)
Sphere$70M$6M14.3x6.9x156.3x103.0x
Pacific Biosciences$160M($153M)5.6x5.6x(5.9x)(6.9x)
Prenetics Global$92M($33M)3.2x1.6x(9.0x)(8.3x)
Myriad Genetics$825M($332M)0.6x0.6x(1.5x)(16.8x)

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Common questions about Geneoscopy

When was Geneoscopy founded?Geneoscopy was founded in 2015.
Where is Geneoscopy headquartered?Geneoscopy is headquartered in Saint Louis, MO, United States.
Is Geneoscopy publicly listed?No, Geneoscopy is a private, VC-backed company.
What is Geneoscopy's valuation?Geneoscopy was last valued at $630M in its Series B in November 2021.
How much funding has Geneoscopy raised?Geneoscopy has raised $218M across 4 funding rounds.
What was Geneoscopy's last funding round?Geneoscopy's last funding round was a $105M Series C in January 2025, led by Bio-Rad Laboratories.
Who are Geneoscopy's investors?Geneoscopy's investors include Lightchain, Labcorp, NT Investments, Cultivation Capital, Morningside, BioGenerator, SINC Fund, Lightchain Capital, Innovatus Capital Partners, Tri Locum Partners and 8 others.
Which companies are comparable to Geneoscopy?Companies comparable to Geneoscopy include MedGenome, Castle Biosciences, Everly Health, uBiome, Atrys Health and Genome Medical.

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