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- bit.bio
bit.bio Funding, Investors & Competitors
bit.bio has raised $225M across 5 funding rounds, most recently a $50M Series C in January 2026.
Last bit.bio funding round
$50M
Series C · Jan 2026
Cumulative funding bit.bio raised
$225M
across 5 funding rounds
Key investors in bit.bio
Tencent
ARCH Venture Partners
Puhua Capital
Foresite Capital
BlueYard Capital
M&G Investments
Milad Alucozai
Metaplanet
About bit.bio
bit.bio is a Cambridge, UK-based biotechnology company spun out of the University of Cambridge in 2016. It develops human cell programming technology, built on its opti-ox platform and AI-enabled discovery methods, that converts induced pluripotent stem cells into specific, reproducible human cell types for use in drug discovery, safety testing, and toxicology. The company positions its manufactured cells as a scalable alternative to animal testing for pharmaceutical, biotech, and research organizations.
Founded
2016
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
bit.bio Funding History
bit.bio has raised a total of $225M across 5 funding rounds.
bit.bio's first fundraising round was a $500K seed round in November 2017. The most recent completed round was a $50M Series C in January 2026.
bit.bio funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Jan 2026 | Series C | M&G Investments (lead) | $50M | bit.bio, a Cambridge-based biotechnology company spun out from the University of Cambridge in 2016, develops human cell programming technology using its opti-ox platform and AI-enabled discovery to convert iPSCs into specific, reproducible cell types for drug discovery, safety testing, and toxicology, reducing reliance on animal testing. The company raised a $50 million Series C funding round on January 9, 2026, led by M&G Investments through its Crossover strategy, funding product development, global operations expansion, manufacturing capacity, and AI dataset generation. This round follows prior funding, with bit.bio having raised over $200 million previously from investors including ARCH Venture Partners, BlueYard Capital, Charles River Laboratories, Foresite Capital, Milky Way, National Resilience, and Tencent, and some sources noting total funding up to $622 million across six rounds, including a $20-30 million raise in late 2024 also led by M&G. In 2025, bit.bio underwent a strategic restructuring, abandoning internal cell therapy development—including a liver cell therapy program nearing clinical trials—and focusing on its platform and tools for research and manufacturing, which involved job cuts and leadership changes like founder Mark Kotter stepping down and Jonathan Milner joining the board. M&G's investment, made on behalf of its £130 billion With Profits Fund, supports bit.bio's scale-up as patient growth equity with a path to public markets, positioning it to enter the multi-billion toxicology market and enhance commercial readiness. CEO Przemek Obloj emphasized accelerating from in silico models to safety testing, while M&G's Cornel Chiriac highlighted bit.bio's reliable, scalable technology as a UK success story for international growth. |
| Dec 2024 | Undisclosed stage | M&G Investments (lead); Puhua Capital; BlueYard Capital; Tencent; Milky Way Ventures; ARCH Venture Partners | $30M | bit.bio, a Cambridge, UK-based biotechnology company spun out from the University of Cambridge in 2016, develops human cell programming technology using its opti-ox platform and AI-enabled discovery to produce defined, reproducible human cells from iPSCs for research, drug discovery, safety testing, and cell therapy applications. The company positions its products as scalable alternatives to animal testing, targeting markets in toxicology, drug development, and biomedical research tools. In December 2024, bit.bio closed a $30 million bridge financing round led by M&G Investments through its Crossover strategy, with participation from existing investors ARCH Venture Partners, BlueYard Capital, Milky Way Ventures, Puhua Capital, and Tencent. This funding aimed to accelerate bit.bio's transformation into a leading provider of human cells, expand board expertise with figures like Jonathan Milner as interim CEO and Mark Kotter as vice chairman, and support growth in research and drug discovery tools. The round underscored strong investor confidence amid a challenging biotech market, marking M&G's entry as the first UK institutional investor. The financing preceded a 2025 strategic reset, where bit.bio restructured by abandoning internal cell therapy development—including a liver cell therapy program nearing clinical trials—and focusing on its cell programming platform and tools business, which involved job cuts. Following the bridge round, bit.bio secured a $50 million Series C in early 2026, again led by M&G Investments, to scale operations globally, expand into toxicology, enhance manufacturing, and build AI datasets. Cumulative funding exceeded $200 million from investors including Charles River Laboratories, Foresite Capital, and National Resilience. The company aims to become a preferred partner for pharma, biotech, and research organizations, leveraging its technology for reliable, commercial-ready cell production. |
| Nov 2021 | Series B | Charles River; Puhua Capital; Milad Alucozai; Tencent; Foresite Capital; ArchVentures SA; Metaplanet; Good AI Capital; Resilience | $103M | - |
| Jun 2020 | Series A | Rick Klausner (lead); BlueYard Capital; Milad Alucozai; Foresite Capital; ARCH Venture Partners | $42M | bit.bio, a Cambridge-based synthetic biology company founded in 2016 as a University of Cambridge spinout, develops opti-ox technology to enable highly efficient and consistent reprogramming of human cells for research, drug discovery, and cell therapy applications. The company aims to produce every human cell type scalably, addressing bottlenecks in drug development and cell therapies where failure rates are high and less than 3% of new drugs reach clinical stages. On June 13, 2020, bit.bio closed a $41.5 million Series A funding round led by Rick Klausner (former National Cancer Institute director and founder of Lyell Immunopharma, Juno, and Grail), with participation from ARCH Venture Partners, BlueYard Capital, Foresite Capital, and Milad Alucozai, bringing total funding to $50 million. The capital supports development of underlying scientific principles, talent growth, and operations to realize ambitions in transitioning biology into engineering and improving precision medicine. At the time, bit.bio had a revenue-generating business through partnerships, including early access to its technology provided to Charles River Laboratories for their preclinical contract research clients in drug discovery. The company produces cell lines in less than a week with 100% purity, contrasting with mixed cell cultures from competitors, to accelerate drug discovery and enable safer cell therapies. Subsequent developments include a 2024 $30 million round led by M&G Investments with existing investors like ARCH Venture Partners and BlueYard Capital, alongside leadership changes such as Jonathan Milner as interim CEO. In 2025-2026, bit.bio raised additional $50 million Series C funding also led by M&G Investments after restructuring to focus on cell programming platform and tools, stepping back from internal cell therapies, and achieving record sales volumes. Total funding exceeds $200 million from investors including Foresite Capital, Charles River Laboratories, Milky Way, Puhua Capital, National Resilience, and Tencent. |
| Nov 2017 | Seed | Jonathan Milner (lead); Nikolaus Starzacher; Darrin Disley; Weslie Janeway | $500K | - |
Who has invested in bit.bio?
18 investors have backed bit.bio across its funding rounds, including Tencent, ARCH Venture Partners, Puhua Capital, Foresite Capital, BlueYard Capital and M&G Investments.
Lead investors include M&G Investments, Rick Klausner and Jonathan Milner.
bit.bio Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 2 | Participant | Nov 2021 | ||
| 2 | Participant | Jun 2020 | ||
| 2 | Participant | Jun 2020 | ||
| 2 | Participant | Nov 2021 | ||
| 2 | Lead | Dec 2024 | ||
| 2 | Participant | Jun 2020 | ||
| 2 | Participant | Jun 2020 | ||
| 1 | Participant | Nov 2021 | ||
| -- | 1 | Participant | Nov 2017 | |
| 1 | Lead | Nov 2017 | ||
| 1 | Participant | Nov 2017 | ||
| 1 | Lead | Jun 2020 | ||
| 1 | Participant | Dec 2024 | ||
This data is available for Pro users. Sign up to see all 18 bit.bio investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free Trialbit.bio Competitors
bit.bio competitors include listed companies like Merck KGaA and Illumina, and private ones like Astromech, Anew Labs, Sinovac Life Sciences and Intrepid Labs.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Private | - | - | $3.8B | - | ||
| Private | - | - | $1.5B | - | ||
| Publicly listed | $24B | $5.3B | $66B | 3.1x | ||
| Private | - | - | $3.3B | - | ||
| Publicly listed | $4.3B | $1.4B | $37B | 8.4x | ||
| Private | - | - | $6.8B | - |
bit.bio Public Comps
bit.bio is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Merck, Roche, Novartis, AstraZeneca, CrowdStrike, SAP and Amgen.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $65B | $28B | 16.5x | 13.1x | 38.7x | 27.0x | |||
| $94B | $40B | 7.2x | 6.8x | 17.0x | 18.3x | |||
| $61B | $17B | 8.7x | 8.1x | 30.6x | 17.6x | |||
| $65B | $28B | 6.3x | 6.2x | 14.7x | 21.0x | |||
| $77B | $26B | 5.0x | 4.9x | 14.6x | 12.4x | |||
| $57B | $22B | 5.5x | 5.5x | 14.2x | 13.3x | |||
| $59B | $19B | 4.8x | 4.5x | 14.6x | 12.7x | |||
| $4.8B | ($12M) | 51.4x | 44.5x | (19816.2x) | 151.0x | |||
This data is available for Pro users. Sign up to see all bit.bio competitors and their valuation data. Start Free Trial | ||||||||
Common questions about bit.bio
| When was bit.bio founded? | bit.bio was founded in 2016. |
| Where is bit.bio headquartered? | bit.bio is headquartered in Cambridge, United Kingdom. |
| Is bit.bio publicly listed? | No, bit.bio is a private, VC-backed company. |
| How much funding has bit.bio raised? | bit.bio has raised $225M across 5 funding rounds. |
| What was bit.bio's last funding round? | bit.bio's last funding round was a $50M Series C in January 2026, led by M&G Investments. |
| Who are bit.bio's investors? | bit.bio's investors include Puhua Capital, BlueYard Capital, Milad Alucozai, Tencent, M&G Investments, Foresite Capital, ARCH Venture Partners, Charles River, Nikolaus Starzacher, Jonathan Milner and 8 others. |
| Which companies are comparable to bit.bio? | Companies comparable to bit.bio include Astromech, Anew Labs, Merck KGaA, Sinovac Life Sciences, Illumina and Intrepid Labs. |
See companies similar to bit.bio
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