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- Vivace Therapeutics
Vivace Therapeutics Valuation, Funding & Investors
Vivace Therapeutics is valued at $90M as of March 2025.
Last Vivace Therapeutics valuation
$90M
Series D · Mar 2025
Last Vivace Therapeutics funding round
$35M
Series D · Mar 2025
Cumulative funding Vivace Therapeutics raised
$105M
across 4 funding rounds
Key investors in Vivace Therapeutics
Canaan Partners
RA Capital Management
Cenova
WuXi Healthcare Ventures
Sequoia Capital
Boxer Capital
About Vivace Therapeutics
Vivace Therapeutics is a San Francisco Bay Area-based oncology company discovering small-molecule drugs targeting novel cancer pathways. The venture-backed firm advances a portfolio of inhibitors for solid tumors resistant to standard therapies, employing structure-based design and AI-driven screening. Vivace Therapeutics maintains labs in South San Francisco, focusing on precision medicines for breast, lung, and pancreatic cancers through partnerships with contract research organizations.
Founded
2014
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Valuation
$90M (Mar 2025)
Sectors
Vivace Therapeutics Valuation
Vivace Therapeutics is currently valued at $90M, based on its Series D in March 2025.
The $35M round was led by RA Capital Management, with participation from Canaan Partners and Cenova.
Vivace Therapeutics valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Mar 2025 | Series D | $90M |
Vivace Therapeutics Funding History
Vivace Therapeutics has raised a total of $105M across 4 funding rounds.
Vivace Therapeutics' first fundraising round was a $15M Series A in January 2015. The most recent completed round was a $35M Series D in March 2025.
Vivace Therapeutics funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Mar 2025 | Series D | RA Capital Management (lead); Canaan Partners; Cenova | $35M | $90M | Vivace Therapeutics is a small molecule discovery and development company focused on first-in-class cancer therapies targeting the Hippo pathway. The company raised $35 million in a Series D financing round on March 12, 2025, led by existing investor RA Capital Management, with participation from Canaan Partners and Cenova Ventures (also referred to as Cenova Capital). This round brings total funding to $105 million across four rounds, following prior Series A, B, and C financings. Cooley advised Vivace on the transaction, having supported the company since its formation including earlier rounds and a spinout. The company had previously closed a $30 million Series C in December 2020 led by Boxer Capital with RA Capital and Canaan Partners participating, planning to advance a clinical candidate targeting YAP-dependent tumors into first-in-human studies in early 2021. Vivace's investors include Canaan Partners (participating in all four rounds), Cenova Ventures, RA Capital Management, WuXi Healthcare Ventures, HongShan, and Boxer Capital. The Series D supports ongoing development of Hippo pathway inhibitors, a novel target in precision oncology for tumorigenesis and drug resistance, with management boasting experience in transformative cancer medicines. |
| Dec 2020 | Series C | Boxer Capital (lead); Canaan Partners; RA Capital Management | $30M | - | Vivace Therapeutics, a biotech company focused on oncology, announced a $30 million Series C financing on December 11, 2020, led by Boxer Capital with participation from new investor RA Capital Management and existing investor Canaan Partners. The funds will support advancing its lead Hippo-YAP pathway inhibitor into human studies in early 2021, targeting tumors dependent on activated YAP, with Dr. Norman Zhou of Boxer Capital joining the board. The company emerged from stealth in 2017 with $40 million in Series A and B funding to pursue Hippo pathway inhibitors and bispecific antibodies called BINspecific antibodies, discovered in the lab of scientific co-founder Bin Liu, Ph.D. Vivace spun out its bispecifics work in 2018 to concentrate resources on drugging the Hippo signaling pathway, previously considered undruggable, by targeting proteins in the TEAD family rather than YAP directly. The Hippo pathway plays a role in various tumor mechanisms, and most of the Series C proceeds will fund clinical trials while also supporting expansion into other indications. CEO Sofie Qiao and CSO Len Post highlighted the pathway's importance in tumorigenesis and drug resistance due to mutations and activated YAP. Prior investors include WuXi Healthcare Ventures, Cenova Capital, and Sequoia Capital China. |
| Jun 2017 | Series B | Cenova (lead); Sequoia Capital (lead); Canaan Partners; WuXi Healthcare Ventures; Mission Bay Capital; Mission BioCapital | $25M | - | - |
| Jan 2015 | Series A | Canaan Partners (lead); WuXi Healthcare Ventures (lead) | $15M | - | Vivace Therapeutics, a cancer-focused drug discovery and development company headquartered in San Mateo, CA, emerged from stealth in 2017. The company develops inhibitors of the Hippo-YAP signaling pathway and BINspecific antibodies targeting pathways like WNT for oncology applications. Scientific co-founders include Kun-liang Guan from UC San Diego and Bin Liu from UCSF. Canaan Partners and WuXi Healthcare Ventures co-led Vivace's $15 million Series A financing, completed in 2015. Mission Bay Capital also participated in the Series A. The company later raised a $25 million Series B led by Cenova Capital with participation from Sequoia Capital China and existing investors, bringing total disclosed financing to $40 million at emergence. Vivace leverages U.S.-China expertise, with WuXi serving as an R&D engine in China guided by U.S. management. Sofie Qiao, Ph.D., serves as president and CEO, with Tim Shannon, M.D., from Canaan Partners as a board member. |
Who has invested in Vivace Therapeutics?
8 investors have backed Vivace Therapeutics across its funding rounds, including Canaan Partners, RA Capital Management, Cenova, WuXi Healthcare Ventures, Sequoia Capital and Boxer Capital.
Lead investors include RA Capital Management, Boxer Capital, Cenova, Sequoia Capital, Canaan Partners and 1 other investor.
Vivace Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 4 | Lead | Jan 2015 | ||
| 2 | Lead | Jun 2017 | ||
| 2 | Lead | Jan 2015 | ||
| 2 | Lead | Dec 2020 | ||
| 1 | Lead | Dec 2020 | ||
| 1 | Lead | Jun 2017 | ||
This data is available for Pro users. Sign up to see all 8 Vivace Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialVivace Therapeutics Competitors
Vivace Therapeutics competitors include listed companies like ImmuCell, IBT, Rallybio and Ensol Biosciences, and private ones like BioApp and Antiva Biosciences.
| Company | HQ | Status | Revenue | EBITDA | Valuation |
|---|---|---|---|---|---|
| Publicly listed | $28M | $2M | $90M | ||
| Publicly listed | - | ($7M) | $91M | ||
| Private | - | - | $89M | ||
| Publicly listed | $858K | ($11M) | $91M | ||
| Publicly listed | $18K | ($3M) | $89M | ||
| Private | - | - | $92M |
Vivace Therapeutics Public Comps
Vivace Therapeutics is still privately-owned, but its public comps include ImmuCell, IBT, Rallybio, Ensol Biosciences, Island Pharmaceuticals, Vistin Pharma, Fractyl Health, AlzeCure Pharma, Abionyx Pharma and MAIA Biotechnology.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $28M | $2M | 3.4x | - | 47.0x | - | |||
| - | ($7M) | - | - | (11.4x) | (6.8x) | |||
| $858K | ($11M) | - | - | - | - | |||
| $18K | ($3M) | 4131.4x | - | (25.0x) | - | |||
| $201K | ($7M) | 394.4x | 253.6x | (11.1x) | (12.1x) | |||
| $48M | $13M | 1.8x | - | 7.0x | - | |||
| - | ($141M) | - | - | (0.8x) | (1.4x) | |||
| - | ($5M) | - | 7.3x | (19.6x) | 17.7x | |||
This data is available for Pro users. Sign up to see all Vivace Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Vivace Therapeutics
| When was Vivace Therapeutics founded? | Vivace Therapeutics was founded in 2014. |
| Where is Vivace Therapeutics headquartered? | Vivace Therapeutics is headquartered in San Francisco, CA, United States. |
| Is Vivace Therapeutics publicly listed? | No, Vivace Therapeutics is a private, VC-backed company. |
| What is Vivace Therapeutics' valuation? | Vivace Therapeutics was last valued at $90M in its Series D in March 2025. |
| How much funding has Vivace Therapeutics raised? | Vivace Therapeutics has raised $105M across 4 funding rounds. |
| What was Vivace Therapeutics' last funding round? | Vivace Therapeutics' last funding round was a $35M Series D in March 2025, led by RA Capital Management. |
| Who are Vivace Therapeutics' investors? | Vivace Therapeutics' investors include Canaan Partners, Cenova, WuXi Healthcare Ventures, RA Capital Management, Boxer Capital, Sequoia Capital, Mission Bay Capital and Mission BioCapital. |
| Which companies are comparable to Vivace Therapeutics? | Companies comparable to Vivace Therapeutics include ImmuCell, IBT, BioApp, Rallybio, Ensol Biosciences and Antiva Biosciences. |
See companies similar to Vivace Therapeutics
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