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- VectivBio
VectivBio Acquisition, Valuation, Funding & Investors
VectivBio was acquired by Ironwood Pharmaceuticals for $1.2B in May 2023, a 43.9x multiple on $27M of revenue.
VectivBio revenue at acquisition
$27M
Last twelve months · May 2023
VectivBio revenue multiple at acquisition
43.9x
EV/Revenue · May 2023
Cumulative funding VectivBio raised
$145M
across 2 funding rounds
About VectivBio
VectivBio is a clinical-stage biotechnology company developing therapies for rare diseases including short bowel syndrome and primary ciliary dyskinesia. Its lead candidate, apraglutide, advances in Phase 3 trials for intestinal rehabilitation. Incorporated in 2019 and headquartered in Basel, Switzerland, VectivBio originated from Therachon programs acquired by Pfizer.
Founded
2019
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Product sales
Revenue
$27M (May 2023)
Valuation
$1.2B (acquired May 2023)
Sectors
VectivBio Acquisition
VectivBio was acquired by Ironwood Pharmaceuticals for $1.2B on 22 May 2023.
The acquisition price implies a 43.9x revenue multiple on $27M of revenue.
Before the acquisition VectivBio had raised $145M across 2 funding rounds.
| Acquirer | Date | Type | Price | EV/Revenue |
|---|---|---|---|---|
| 22 May 2023 | Strategic M&A | $1.2B | 43.9x |
VectivBio Funding History
VectivBio has raised a total of $145M across 2 funding rounds.
VectivBio's first fundraising round was a $35M Series A in January 2020. The most recent completed round was a $110M undisclosed-stage round in October 2020.
VectivBio funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Oct 2020 | Undisclosed stage | Inserm Transfert Initiative; Eventide; Cowen Healthcare Investments; Novo Holdings; Versant Ventures; Tekla Capital Management; Cormorant Capital; Bpifrance; OrbiMed; Surveyor Capital | $110M | VectivBio AG is a clinical-stage biotechnology company focused on developing transformational medicines for patients with serious rare diseases. In October 2020, it closed a $110 million crossover financing round with new investors Surveyor Capital (a Citadel company), Cormorant Capital, and Eventide Asset Management, alongside existing investors Versant Ventures, OrbiMed, Novo Holdings, BPI France, Tekla Healthcare Investors, Inserm Transfert Initiative, and Cowen Healthcare Investments. The proceeds are designated to support the Phase III program for its lead investigational product, apraglutide, aimed at treating short bowel syndrome (SBS), early commercialization activities, and pipeline expansion through business development. Apraglutide, a GLP-2 analog, has completed Phase II studies demonstrating potential for once-weekly dosing, positioning it as a possible best-in-class therapy for SBS across various anatomical disease subtypes. CEO Luca Santarelli highlighted the excitement over the strengthened investor syndicate, while Versant Ventures' Tom Woiwode emphasized support for the company's growth phase. |
| Jan 2020 | Series A | Inserm Transfert Initiative; Cowen Healthcare Investments; Novo Holdings; Versant Ventures; Tekla Capital Management; Bpifrance; OrbiMed | $35M | VectivBio launched in January 2020 with a $35 million financing round from investors including Bpifrance, Cowen Healthcare Investments, Inserm Transfert Initiative, Novo Holdings, OrbiMed, Tekla Capital Management, and Versant Ventures, focusing on developing best-in-disease medicines for patients with serious rare diseases. The company is a clinical-stage biopharmaceutical firm targeting rare conditions, with key programs like apraglutide for short bowel syndrome-intestinal failure (SBS-IF). The company reported net losses including $59.9 million for the year ended December 31, 2020. By 2022, VectivBio recognized $27.3 million in revenue from contracts with customers, primarily from a Japan licensing deal with Asahi Kasei Pharma involving apraglutide intellectual property rights and development activities. The company continued funding operations through subsequent raises, including $179.2 million in equity offerings in 2022 and access to up to EUR equivalent of $75 million in debt financing. Cash and cash equivalents stood at $221.4 million as of December 31, 2022, supporting ongoing Phase 3 trials like STARS for apraglutide. Net losses persisted, reaching $93.7 million in 2022. |
Who has invested in VectivBio?
10 investors have backed VectivBio across its funding rounds, including Bpifrance, OrbiMed, Novo Holdings, Versant Ventures, Cowen Healthcare Investments and Tekla Capital Management.
VectivBio Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 2 | Participant | Jan 2020 | ||
| 2 | Participant | Jan 2020 | ||
| 2 | Participant | Jan 2020 | ||
| 2 | Participant | Jan 2020 | ||
| 2 | Participant | Jan 2020 | ||
| 2 | Participant | Jan 2020 | ||
| 2 | Participant | Jan 2020 | ||
| 1 | Participant | Oct 2020 | ||
This data is available for Pro users. Sign up to see all 10 VectivBio investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
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Start Free TrialAcquisitions by VectivBio
VectivBio has acquired 1 company to date.
Last acquisition by VectivBio was on August 31st 2021. VectivBio acquired Comet Therapeutics for $2M.
Latest Acquisitions by VectivBio
| Description | Comet Therapeutics is a South San Francisco-headquartered clinical-stage biotechnology company developing small-molecule therapies for orphan neurological disorders. Its platform modulates Coenzyme A metabolism to treat conditions like PNPLA6-associated spastic paraplegia and neurodegeneration. The lead program targets lipid accumulation in neurons caused by metabolic dysregulation. Comet advances candidates through partnerships with academic researchers and contract manufacturers. |
| HQ Country | |
| HQ City | - |
| Deal Date | 31 Aug 2021 |
| Valuation | $2M |
| EV/Revenue | |
| EV/EBITDA | |
This data is available for Pro users. Sign up to see all VectivBio acquisitions and their M&A valuation multiples. Start Free Trial | |
VectivBio Competitors
VectivBio competitors include listed companies like TOWA Pharmaceutical, OPKO Health, Uniphar and Replimune Group, and private ones like Abcuro and FibroGen.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $1.8B | $244M | $1.2B | 1.3x | ||
| Private | - | - | $1.2B | - | ||
| Publicly listed | $607M | ($56M) | $1.2B | 2.3x | ||
| Publicly listed | $3.5B | $136M | $1.2B | 0.5x | ||
| Publicly listed | - | ($302M) | $1.2B | 59.4x | ||
| Private | $108M | - | $1.2B | 11.3x |
VectivBio Public Comps
VectivBio is no longer listed, but its public comps include TOWA Pharmaceutical, OPKO Health, Uniphar, Replimune Group, Everest Medicines, Alto Neuroscience, Akums Drugs and Pharma, Chongqing Genrix, Apnimed and Seaport Therapeutics.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $1.8B | $244M | 1.4x | 1.3x | 9.9x | 7.8x | |||
| $607M | ($56M) | 2.2x | 2.3x | (23.3x) | (11.2x) | |||
| $3.5B | $136M | 0.5x | 0.5x | 12.5x | 10.4x | |||
| - | ($302M) | - | 59.4x | (3.7x) | (3.9x) | |||
| $254M | ($72M) | 4.6x | 2.9x | (16.3x) | 22.3x | |||
| - | ($67M) | - | - | (14.9x) | (9.7x) | |||
| $443M | $54M | 2.4x | 2.2x | 19.9x | 16.6x | |||
| $34M | ($70M) | 32.6x | 33.1x | (16.0x) | - | |||
This data is available for Pro users. Sign up to see all VectivBio competitors and their valuation data. Start Free Trial | ||||||||
Common questions about VectivBio
| When was VectivBio founded? | VectivBio was founded in 2019. |
| Where is VectivBio headquartered? | VectivBio is headquartered in Basel, Switzerland. |
| Is VectivBio publicly listed? | No, VectivBio was acquired by Ironwood Pharmaceuticals in May 2023. |
| Who acquired VectivBio? | VectivBio was acquired by Ironwood Pharmaceuticals in May 2023. |
| How much was VectivBio acquired for? | VectivBio was acquired for $1.2B in May 2023, a 43.9x revenue multiple. |
| How much funding has VectivBio raised? | VectivBio has raised $145M across 2 funding rounds. |
| What was VectivBio's last funding round? | VectivBio's last funding round was a $110M undisclosed-stage round in October 2020. |
| Who are VectivBio's investors? | VectivBio's investors include Inserm Transfert Initiative, Cowen Healthcare Investments, Novo Holdings, Versant Ventures, Tekla Capital Management, Bpifrance, OrbiMed, Eventide, Cormorant Capital and Surveyor Capital. |
| Which companies are comparable to VectivBio? | Companies comparable to VectivBio include TOWA Pharmaceutical, Abcuro, OPKO Health, Uniphar, Replimune Group and FibroGen. |
| How many companies has VectivBio acquired? | VectivBio has acquired 1 company, including Comet Therapeutics. |
| What was the largest acquisition by VectivBio? | The $2M acquisition of Comet Therapeutics in August 2021 is the largest acquisition VectivBio has made to date. |
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