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- Strand Therapeutics
Strand Therapeutics Valuation, Funding & Investors
Strand Therapeutics is valued at $550M as of August 2025.
Last Strand Therapeutics valuation
$550M
Series B · Aug 2025
Last Strand Therapeutics funding round
$153M
Series B · Aug 2025
Cumulative funding Strand Therapeutics raised
$256M
across 4 funding rounds
Key investors in Strand Therapeutics
Playground Global
ANRI
Alexandria Venture Investments
Kinnevik
Redmile Group
Creative Destruction Lab (CDL)
About Strand Therapeutics
Strand Therapeutics is a Cambridge-headquartered biotechnology firm founded in 2017 that engineers programmable mRNA medicines using synthetic biology principles. The platform deploys logic circuits within cells to detect tumor-specific signals and produce cancer-fighting proteins on demand, such as cytokines for immunotherapy. Their lead candidates target solid tumors including glioblastoma and head-and-neck cancers through intravenous administration. Strand Therapeutics collaborates with academic institutions like MIT and has progressed multiple programs into preclinical testing for oncology applications.
Founded
2017
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Licensing
Valuation
$550M (Aug 2025)
Strand Therapeutics Valuation
Strand Therapeutics is currently valued at $550M, based on its Series B in August 2025.
The $153M round was led by Kinnevik.
Strand Therapeutics valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Aug 2025 | Series B | $550M |
Strand Therapeutics Funding History
Strand Therapeutics has raised a total of $256M across 4 funding rounds.
Strand Therapeutics' first fundraising round was a $6M seed round in June 2019. The most recent completed round was a $153M Series B in August 2025.
Strand Therapeutics funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Aug 2025 | Series B | Kinnevik (lead) | $153M | $550M | Strand Therapeutics is a clinical-stage biotechnology company developing programmable mRNA therapies that integrate synthetic biology with genetic logic circuits for precise control in targeted cells, focusing on cancer and serious diseases. Its lead program, STX-001, is a self-replicating mRNA therapy delivering interleukin-12 (IL-12) into the tumor microenvironment, showing multiple RECIST responses including complete responses in Phase 1 trials for advanced solid tumors as of June 2025, with ongoing studies as monotherapy or with Keytruda. The pipeline includes STX-003, a systemically administered mRNA therapy with tumor-targeted IL-12 delivery, advancing toward Phase 1 in 2026. In August 2025, Strand raised $153 million in a Series B round led by Kinnevik with a $35 million investment, joined by new investors including Regeneron Ventures, ICONIQ, Amgen Ventures, Alderline Group, JIC-VGI, LG Technology Ventures, and Gradiant Corporation, plus existing backers like FPV Ventures, Playground Global, Eli Lilly, ANRI, and Potentum. This brings total funding to over $250 million, following a $97 million Series A in 2022. Ala Alenazi, Ph.D., from Kinnevik joined the board. The proceeds will support clinical advancement of STX-001, expansion of STX-003 into trials, and broader platform development for safer, more effective mRNA therapeutics. Early STX-001 data demonstrated systemic immune activation, anti-tumor responses across tumor types, and a favorable safety profile, validating the programmable RNA approach amid growing interest despite mRNA policy challenges. Strand, founded in 2017 by CEO Jake Becraft and Tasuku Kitada as an MIT spinout, positions programmable mRNA as the next frontier, with Kinnevik's Christian Scherrer highlighting outstanding clinical data and potential to reshape cancer treatment. |
| Nov 2022 | Series A | FPV Ventures (lead); Potentum partners; Eli Lilly & Company Foundation; Playground Global | $45M | - | Strand Therapeutics is a programmable mRNA company developing curative therapies for cancer and other diseases, founded in 2019 and headquartered in Boston, Massachusetts. The company's platform aims to create long-acting mRNA therapies that stimulate immune responses against tumors, positioning mRNA as a therapeutic modality beyond vaccines. In November 2022, Strand announced a Series A1 round adding $45 million in funding, bringing the total Series A to $97 million. The Series A1 was led by new investor FPV Ventures, founded by Wesley Chan (Google Analytics, Google Voice) and Pegah Ebrahimi (former COO/CIO at Morgan Stanley and COO of Cisco Collaboration). At this pre-clinical stage, Strand had not yet disclosed revenue, EBITDA, or other financial metrics. The company subsequently raised $153 million in a Series B round (2025) led by Kinnevik with participation from Regeneron Ventures, ICONIQ Capital, Amgen Ventures, and others, bringing total capital raised to over $250 million. By the 2025 ASCO meeting, lead asset STX-001 had demonstrated multiple RECIST responses in Phase 1 clinical data. |
| Jun 2021 | Series A | ANRI; Redmile Group; BeiGene; Camford Capital; Playground Global | $52M | - | Strand Therapeutics, an MIT spinout founded in 2017 by leaders in mRNA-based synthetic biology, raised $52 million in an oversubscribed Series A round on June 23, 2021, led by Redmile Group, BeiGene, and Camford Capital, with participation from existing investors Playground Global and ANRI. This brought the company's total funding to $66 million, following a $6 million seed round in 2019 led by Playground Global. The proceeds were earmarked to expand its programmable mRNA platform and advance its lead drug candidate into Phase 1 clinical trials expected in early 2022, focusing on cancer immunotherapy and other diseases through self-replicating mRNAs with logic circuits for precise control of therapeutic activity in targeted tissues. Strand's platform develops next-generation mRNA therapeutics that sense cell-type specific signatures to enable controlled delivery of treatments, aiming for high efficacy and low toxicity in addressing solid tumors and life-threatening conditions poorly served by traditional therapies. The technology combines self-replication genes with synthetic biology logic, originating from MIT's Synthetic Biology Center research supported by DARPA, similar to early Moderna funding. A January 2021 BeiGene partnership included a $5 million investment rolled into this Series A. |
| Jun 2019 | Seed | Playground Global (lead); ANRI; Alexandria Venture Investments; Creative Destruction Lab (CDL) | $6M | - | Strand Therapeutics, a biotechnology company developing gene therapies powered by synthetic biology, completed a $6 million seed financing round on June 4, 2019. The round was led by Playground Global with participation from Alexandria Venture Investments, ANRI, and private investors. Funds supported advancement of its programmable mRNA therapeutics platform for next-generation mRNA-based cancer immunotherapies. |
Who has invested in Strand Therapeutics?
11 investors have backed Strand Therapeutics across its funding rounds, including Playground Global, ANRI, Alexandria Venture Investments, Kinnevik, Redmile Group and Creative Destruction Lab (CDL).
Lead investors include Kinnevik, FPV Ventures and Playground Global.
Strand Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Jun 2019 | ||
| 2 | Participant | Jun 2019 | ||
| 1 | Participant | Nov 2022 | ||
| 1 | Participant | Jun 2021 | ||
| 1 | Participant | Jun 2019 | ||
| 1 | Lead | Nov 2022 | ||
| 1 | Participant | Nov 2022 | ||
| 1 | Participant | Jun 2021 | ||
| 1 | Participant | Jun 2019 | ||
This data is available for Pro users. Sign up to see all 11 Strand Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialStrand Therapeutics Competitors
Strand Therapeutics competitors include listed companies like Ocumension and Kamada, and private ones like Shoreline Biosciences, SmartCella, Ring Therapeutics and Ollin Biosciences.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $120M | ($3M) | $548M | - | ||
| Private | - | - | $528M | - | ||
| Private | - | - | $575M | - | ||
| Private | - | - | $591M | - | ||
| Publicly listed | $180M | $37M | $501M | 2.3x | ||
| Private | - | - | $500M | - |
Strand Therapeutics Public Comps
Strand Therapeutics is still privately-owned, but its public comps include Ocumension, Capricor Therapeutics, Eupraxia Pharmaceuticals, BrainsWay, Arvinas, Regenxbio, Clarity Pharmaceuticals, SD Biosensor, Delcath Systems and Cerus.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $120M | ($3M) | 4.1x | - | (178.3x) | - | |||
| - | ($100M) | - | 6.1x | (4.0x) | (2.6x) | |||
| - | ($40M) | - | - | (11.3x) | (9.3x) | |||
| $52M | $7M | 9.3x | 7.6x | 71.7x | 41.7x | |||
| $263M | ($114M) | - | - | - | - | |||
| $170M | ($133M) | 3.0x | 3.0x | (3.8x) | (3.2x) | |||
| $6M | ($75M) | 74.8x | 67.8x | (5.7x) | (5.5x) | |||
| $517M | ($509M) | 0.8x | - | (0.8x) | - | |||
This data is available for Pro users. Sign up to see all Strand Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Strand Therapeutics
| When was Strand Therapeutics founded? | Strand Therapeutics was founded in 2017. |
| Where is Strand Therapeutics headquartered? | Strand Therapeutics is headquartered in United States. |
| Is Strand Therapeutics publicly listed? | No, Strand Therapeutics is a private, VC-backed company. |
| What is Strand Therapeutics' valuation? | Strand Therapeutics was last valued at $550M in its Series B in August 2025. |
| How much funding has Strand Therapeutics raised? | Strand Therapeutics has raised $256M across 4 funding rounds. |
| What was Strand Therapeutics' last funding round? | Strand Therapeutics' last funding round was a $153M Series B in August 2025, led by Kinnevik. |
| Who are Strand Therapeutics' investors? | Strand Therapeutics' investors include Playground Global, ANRI, Potentum partners, Redmile Group, Alexandria Venture Investments, FPV Ventures, Eli Lilly & Company Foundation, BeiGene, Creative Destruction Lab (CDL), Camford Capital and 1 other. |
| Which companies are comparable to Strand Therapeutics? | Companies comparable to Strand Therapeutics include Ocumension, Shoreline Biosciences, SmartCella, Ring Therapeutics, Kamada and Ollin Biosciences. |
See companies similar to Strand Therapeutics
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