- Companies
- ReViral
ReViral Acquisition, Valuation, Funding & Investors
ReViral was acquired by Pfizer for $525M in April 2022, a 38.0x multiple on $14M of revenue.
ReViral revenue at acquisition
$14M
Last twelve months · Apr 2022
ReViral revenue multiple at acquisition
38.0x
EV/Revenue · Apr 2022
Cumulative funding ReViral raised
$121M
across 4 funding rounds
About ReViral
ReViral is a clinical-stage biopharmaceutical company focused on respiratory syncytial virus treatments. Sisunersin, its lead fusion inhibitor, enters phase 2 trials for infants and high-risk adults hospitalized with RSV. The small molecule drug blocks viral entry into cells, addressing an unmet need in antiviral therapy. Headquartered in Stevenage, United Kingdom, ReViral partners with Roche for global development and commercialization outside Asia.
Founded
2011
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Licensing
Revenue
$14M (Apr 2022)
Valuation
$525M (acquired Apr 2022)
Sectors
ReViral Acquisition
ReViral was acquired by Pfizer for $525M on 7 April 2022.
The acquisition price implies a 38.0x revenue multiple on $14M of revenue.
Before the acquisition ReViral had raised $121M across 4 funding rounds.
Pfizer acquired ReViral, a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing novel antiviral therapeutics targeting respiratory syncytial virus (RSV). ReViral's lead candidate, sisunatovir, is an oral inhibitor that blocks RSV fusion to host cells, with Fast Track designation from the FDA, positive Phase 2 data in adults, and ongoing Phase 2 in infants. The company also had an RSV N-protein replication inhibitor in Phase 1. The deal, announced in April 2022 and completed later that year, totals up to $525 million in upfront and development milestone payments for full acquisition. It bolsters Pfizer's anti-infective pipeline, complementing its RSV vaccine efforts, with potential annual revenue exceeding $1.5 billion if successful. Pfizer leverages its R&D, manufacturing, and commercial capabilities to advance these therapies addressing unmet RSV needs in adults and pediatrics. Executives highlighted strategic fit: Pfizer's commitment to infectious diseases via vaccines and therapeutics, validated by ReViral's antiviral expertise. Post-acquisition, Pfizer terminated development of sisunatovir and another asset due to strategic considerations.
| Acquirer | Date | Type | Price | EV/Revenue |
|---|---|---|---|---|
| 7 Apr 2022 | Strategic M&A | $525M | 38.0x |
ReViral Funding History
ReViral has raised a total of $121M across 4 funding rounds.
ReViral's first fundraising round was a $1M seed round in December 2014. The most recent completed round was a $44M Series C in August 2020.
ReViral funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Aug 2020 | Series C | CR-CP Life Science Fund (lead); Novo Holdings; New Leaf Venture Partners; Green Sands Equity; Andera Partners; OrbiMed; Perceptive Advisors; Brace Pharma | $44M | ReViral Ltd. is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing novel antiviral therapeutics targeting respiratory syncytial virus (RSV). The company's lead program is sisunatovir, a wholly-owned fusion protein inhibitor in Phase 2 clinical development, complemented by an N-protein replication inhibitor program advancing into Phase 1. In August 2020, ReViral closed a $44 million Series C financing round led by CR-CP Life Science Fund, with participation from Andera Partners, Brace Pharma Capital, Green Sands Equity, New Leaf Venture Partners, Novo Holdings, OrbiMed Advisors, and Perceptive Advisors. The funding was designated to support Phase 2 clinical development for sisunatovir and to advance the N-protein replication inhibitor program into Phase 1 trials. CR-CP Life Science Fund, a $300 million venture capital vehicle jointly sponsored by China Resources Group and Charoen Pokphand Group, brought strategic healthcare investor backing to the company, with CR-CP's CEO Jason Zhou joining ReViral's Board of Directors. |
| Aug 2018 | Series B | New Leaf Venture Partners (lead); Novo Ventures (lead); Andera Partners; OrbiMed; Perceptive Advisors; Brace Pharma | $55M | ReViral is a UK-based antiviral drug discovery company focused on developing treatments for Respiratory Syncytial Virus (RSV) infections, the leading cause of respiratory tract infections in infants and a significant pathogen causing 30 million infections and 200,000 deaths annually in children under five. The company raised $55 million in a Series B financing round in August 2018, jointly led by New Leaf Venture Partners and Novo Ventures, with participation from new investor Perceptive Advisors and existing investors Andera Partners, OrbiMed, and Brace Pharma Capital. This followed a $21 million Series A in 2015. The proceeds were allocated to advance ReViral's lead candidate RV521, a potent orally bioavailable RSV fusion inhibitor, into Phase IIa clinical trials in pediatric and adult patients, including an international multicentre pediatric trial and studies in adult stem cell transplant patients. Positive Phase IIa data from 66 patients showed significant reductions in viral load (p=0.006) and symptom scores (p=0.001) with RV521 compared to placebo. Funds also supported development of additional RSV replication inhibitors. ReViral's approach targets RSV by inhibiting viral fusion with host cells, positioning it against competitors like Gilead and Johnson & Johnson in a market valued at $820 million in 2016, projected to reach $2.12 billion by 2025. The round validated the company's science amid unmet needs, with new board members from lead investors. |
| Sep 2015 | Series A | Andera Partners (lead); OrbiMed (lead); Brace Pharma | $21M | ReViral is a London-based antiviral drug discovery and development company focused on diseases caused by Respiratory Syncytial Virus (RSV), advancing small molecule inhibitors like RV521 into clinical trials. On September 8, 2015, it completed a $21 million Series A financing jointly led by Edmond de Rothschild Investment Partners (now associated with Andera Partners) and OrbiMed, with new investment from Brace Pharma Capital and conversion of a Wellcome Trust Seeding Drug Discovery Award loan into equity. The funds supported clinical development, including IND-enabling studies and early-phase trials for its RSV fusion inhibitors. Board representatives from the lead investors and Wellcome Trust joined the board. This Series A marked ReViral's transition from seed-funded preclinical research to a clinical-stage biotech, positioning it as a leader in the RSV space amid unmet needs for treatments in high-risk populations like infants and the immunocompromised. Subsequent rounds included a $55 million Series B in 2018 led by New Leaf Venture Partners and Novo Ventures, with participation from Andera Partners, OrbiMed, Brace Pharma Capital, and Perceptive Advisors, to advance RV521 into Phase IIa trials and further N-protein inhibitors. A $44 million Series C followed, led by CR-CP Life Science Fund, supporting Phase 2 for sisunatovir and preclinical N-protein programs. ReViral progressed its pipeline with sisunatovir in global Phase 2 studies for pediatric and adult stem-cell transplant patients. In 2022, Pfizer agreed to acquire ReViral for up to $525 million including milestones, recognizing its RSV therapeutics amid growing market interest, with Andera Partners highlighting their role since the 2015 Series A. |
| Dec 2014 | Seed | - | $1M | - |
Who has invested in ReViral?
9 investors have backed ReViral across its funding rounds, including OrbiMed, Andera Partners, Brace Pharma, Perceptive Advisors, New Leaf Venture Partners and Novo Holdings.
Lead investors include CR-CP Life Science Fund, New Leaf Venture Partners, Novo Ventures, Andera Partners and OrbiMed.
ReViral Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Sep 2015 | ||
| 3 | Lead | Sep 2015 | ||
| 3 | Participant | Sep 2015 | ||
| 2 | Lead | Aug 2018 | ||
| 2 | Participant | Aug 2018 | ||
| 1 | Lead | Aug 2018 | ||
| 1 | Lead | Aug 2020 | ||
This data is available for Pro users. Sign up to see all 9 ReViral investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialReViral Competitors
ReViral competitors include listed companies like Indaptus Therapeutics, Chabiotech, Entera Bio and Ovid Therapeutics, and private ones like Shoreline Biosciences and Bambusa Therapeutics.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | - | ($21M) | $524M | - | ||
| Publicly listed | $923M | ($32M) | $527M | - | ||
| Publicly listed | $42K | ($11M) | $523M | 42813.7x | ||
| Publicly listed | $7M | ($17M) | $527M | 159.2x | ||
| Private | - | - | $528M | - | ||
| Private | - | - | $515M | - |
ReViral Public Comps
ReViral is no longer listed, but its public comps include Indaptus Therapeutics, Chabiotech, Entera Bio, Ovid Therapeutics, TaiMed Biologics, Beximco Pharmaceuticals, Tectonic Therapeutic, Assembly Biosciences, Novartis India and Autolus Therapeutics.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($21M) | - | - | (24.6x) | - | |||
| $923M | ($32M) | 1.4x | - | (41.0x) | - | |||
| $42K | ($11M) | 12199.0x | 42813.7x | (44.6x) | - | |||
| $7M | ($17M) | 58.3x | 159.2x | (24.7x) | - | |||
| $19M | ($1M) | 25.8x | - | (487.5x) | - | |||
| $399M | $97M | 1.4x | 1.3x | 5.7x | 5.3x | |||
| - | ($83M) | - | - | (3.8x) | - | |||
| $72M | ($12M) | 2.7x | 3.0x | (16.5x) | 9.1x | |||
This data is available for Pro users. Sign up to see all ReViral competitors and their valuation data. Start Free Trial | ||||||||
Common questions about ReViral
| When was ReViral founded? | ReViral was founded in 2011. |
| Where is ReViral headquartered? | ReViral is headquartered in Stevenage, United Kingdom. |
| Is ReViral publicly listed? | No, ReViral was acquired by Pfizer in April 2022. |
| Who acquired ReViral? | ReViral was acquired by Pfizer in April 2022. |
| How much was ReViral acquired for? | ReViral was acquired for $525M in April 2022, a 38.0x revenue multiple. |
| How much funding has ReViral raised? | ReViral has raised $121M across 4 funding rounds. |
| What was ReViral's last funding round? | ReViral's last funding round was a $44M Series C in August 2020, led by CR-CP Life Science Fund. |
| Who are ReViral's investors? | ReViral's investors include Andera Partners, OrbiMed, Brace Pharma, New Leaf Venture Partners, Perceptive Advisors, Novo Ventures, CR-CP Life Science Fund, Novo Holdings and Green Sands Equity. |
| Which companies are comparable to ReViral? | Companies comparable to ReViral include Indaptus Therapeutics, Chabiotech, Entera Bio, Ovid Therapeutics, Shoreline Biosciences and Bambusa Therapeutics. |
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