Dewpoint Therapeutics Valuation, Funding & Investors

Dewpoint Therapeutics is valued at $504M as of September 2025.

Last Dewpoint Therapeutics valuation

$504M

Series D · Sep 2025

Last Dewpoint Therapeutics funding round

$59M

Series D · Sep 2025

Cumulative funding Dewpoint Therapeutics raised

$346M

across 4 funding rounds

Key investors in Dewpoint Therapeutics

  • Polaris Partners
  • Samsara BioCapital
  • Leaps by Bayer
  • EcoR1 Capital
  • ARCH Venture Partners
  • Maverick Ventures

Dewpoint Therapeutics Overview

About Dewpoint Therapeutics

Dewpoint Therapeutics is a Boston, Massachusetts-headquartered biotechnology company founded in 2018 modulating biomolecular condensates for diseases like ALS and cancer. The Condensate Dialysis platform screens compounds disrupting pathological condensates using AI-driven imaging, with lead candidates targeting FUS protein aggregates entering Phase 1 trials in 2023.


Founded

2018

HQ

United StatesBoston, MA

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Valuation

$504M (Sep 2025)

Dewpoint Therapeutics Valuation

Dewpoint Therapeutics is currently valued at $504M, based on its Series D in September 2025.

Dewpoint Therapeutics valuation by funding round

Dewpoint Therapeutics valuation by funding round
DateStageValuation
Sep 2025Series D$504M

Dewpoint Therapeutics Funding History

Dewpoint Therapeutics has raised a total of $346M across 4 funding rounds.

Dewpoint Therapeutics' first fundraising round was a $60M Series A in January 2019. The most recent completed round was a $59M Series D in September 2025.

Dewpoint Therapeutics funding rounds

Dewpoint Therapeutics funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Sep 2025Series D-$59M$504MDewpoint Therapeutics is a biotechnology company pioneering condensate biology to develop first-in-class condensate modulators (c-mods) for difficult-to-treat diseases across oncology, neurodegenerative, cardiopulmonary, and metabolic areas. Its proprietary AI/ML-powered platform supports a broad drug discovery pipeline, with key programs like DPTX3186 targeting gastric cancer by disrupting oncogenic Wnt signaling via β-catenin condensates, and another targeting the undruggable MYC protein. The company maintains strategic collaborations with Bayer, Novo Nordisk, and Mitsubishi Tanabe Pharma to advance condensate-based medicines. Prior fundings include a $150 million Series C in February 2022 led by SoftBank Vision Fund 2, bringing total raised to approximately $346 million over five rounds. The round provides operational runway into early 2027, funding the initiation of clinical trials for DPTX3186 by year-end 2025, aiming for early proof-of-concept by end-2026, and accelerating MYC-targeted c-mod development. Dewpoint has faced challenges, including reported losses of alliances with Merck and Pfizer, and staff layoffs, but continues to progress clinically with orphan drug designation for DPTX3186 and partnerships like the up-to-$480 million ALS deal with Mitsubishi Tanabe.
Feb 2022Series CSoftBank Group (lead); General Catalyst; Polaris Partners; Leaps by Bayer; Maverick Ventures; 3E Bioventures; Mubadala; Samsara BioCapital; EcoR1 Capital; Mirae Asset Capital; NS Investment; ARCH Venture Partners$150M-Dewpoint Therapeutics, a biomolecular condensates company focused on drug discovery, completed a $150 million Series C financing on February 3, 2022, led by SoftBank Vision Fund 2, with new investors including General Catalyst, Mubadala Capital Ventures, 3E Bioventures Capital, Mirae Asset Capital, and NS Investment, alongside existing investors Leaps by Bayer, Polaris Partners, Samsara BioCapital, ARCH Venture Partners, EcoR1 Capital, and Maverick Ventures. The proceeds are designated to advance multiple pipeline programs through IND-enabling studies, invest in the company's fully integrated multi-component biology platform and AI-driven data science platform, and expand research infrastructure to support over 20 discovery and development programs across oncology, neuromuscular, cardiopulmonary, and virology indications. The financing underscores investor confidence in Dewpoint's leadership in biomolecular condensates, an emerging field for addressing diseases through condensate dysregulation, with CEO Ameet Nathwani highlighting the syndicate's support for breakthrough medicines and SoftBank's Vikas Parekh praising the team's experience and pharmaceutical partnerships. Dewpoint maintains collaborations such as a Pfizer deal valued at up to $239 million for myotonic dystrophy type 1 treatments, reflecting strategic alliances in rare genetic disorders.
Sep 2020Series BARCH Venture Partners (lead); Bellco Capital; Polaris Partners; Innovation Endeavors; Leaps by Bayer; Maverick Ventures; Samsara BioCapital; EcoR1 Capital$77M-Dewpoint Therapeutics, a biotechnology company pioneering drugs targeting biomolecular condensates—non-membrane-bound cellular structures driving disease through protein interactions—raised $77 million in an oversubscribed Series B financing on September 29, 2020. ARCH Venture Partners led the round, with participation from new investors Maverick Ventures and Bellco Capital, alongside existing backers Leaps by Bayer, EcoR1 Capital, Polaris Partners, Samsara BioCapital, and Innovation Endeavors. The funds supported platform development to identify compounds modulating condensates and expansion into oncology, neurodegeneration, metabolic disease, and immunology. Prior to the Series B, Dewpoint launched in January 2019 with a $60 million Series A led by Polaris Partners, joined by Samsara BioCapital, 6 Dimensions Capital, EcoR1 Capital, Alexandria Venture Investments, and Leaps by Bayer. By mid-2020, the company had secured major collaborations: an exclusive deal with Merck in July 2020 for HIV treatments using its condensate platform, and a November 2019 partnership with Bayer leveraging its small molecule library for cardiovascular and gynecological diseases. Subsequent financings included a $150 million Series C in February 2022 led by SoftBank Vision Fund 2, with General Catalyst, Mubadala Capital, 3E Bioventures Capital, Mirae Asset Capital, and NS Investment as new investors, plus prior backers; proceeds advanced pipeline programs in oncology, neuromuscular, cardiopulmonary, and virology to IND stage while enhancing AI-driven data platforms. Later rounds totaled over $287 million across four, per aggregated reports, with a Series D grant noted in 2025.
Jan 2019Series APolaris Partners (lead); Alexandria Venture Investments; Leaps by Bayer; Samsara BioCapital; EcoR1 Capital; 6 Dimensions Capital$60M-Dewpoint Therapeutics launched on January 30, 2019, with a $60 million Series A financing round led by founding investor Polaris Partners, joined by Samsara BioCapital, 6 Dimensions Capital, EcoR1 Capital, Alexandria Venture Investments, and Leaps by Bayer. The Cambridge, Massachusetts-based company focuses on drug discovery targeting biomolecular condensates, membraneless organelles that concentrate proteins and nucleic acids to drive cellular chemical reactions, an understudied area due to challenges with traditional methods like protein crystallography. This approach builds on research by founders Anthony Hyman from the Max Planck Institute of Molecular Cell Biology and Genetics and Richard Young from the Whitehead Institute. The financing supports Dewpoint's efforts to industrialize drugging condensates, with teams in Cambridge and Dresden, Germany, and a scientific advisory board including MIT professor Bob Langer. The company aims to address diseases involving condensate dysregulation, such as cancer, cardiovascular conditions, immunology, neurodegenerative disorders, virology, and women's health. Amir Nashat, managing partner at Polaris Partners, served as CEO at launch. Subsequent rounds include a $77 million Series B in September 2020 led by ARCH Venture Partners and a $150 million Series C in February 2022 led by SoftBank Vision Fund 2.

Who has invested in Dewpoint Therapeutics?

16 investors have backed Dewpoint Therapeutics across its funding rounds, including Polaris Partners, Samsara BioCapital, Leaps by Bayer, EcoR1 Capital, ARCH Venture Partners and Maverick Ventures.

Lead investors include SoftBank Group, ARCH Venture Partners and Polaris Partners.


Dewpoint Therapeutics Investors

Investors in Dewpoint Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Polaris PartnersUnited StatesBoston, MA3LeadJan 2019
Leaps by BayerGermanyLeverkusen3ParticipantJan 2019
Samsara BioCapitalUnited StatesSan Francisco, CA3ParticipantJan 2019
EcoR1 CapitalUnited StatesSan Francisco, CA3ParticipantJan 2019
Maverick VenturesUnited StatesUnited States2ParticipantSep 2020
ARCH Venture PartnersUnited StatesChicago, IL2LeadSep 2020
General CatalystUnited StatesSan Francisco, CA1ParticipantFeb 2022
Bellco CapitalUnited StatesLos Angeles, CA1ParticipantSep 2020
SoftBank GroupJapanTokyo1LeadFeb 2022
Alexandria Venture InvestmentsUnited StatesLos Angeles, CA1ParticipantJan 2019
Innovation EndeavorsUnited StatesSan Francisco, CA1ParticipantSep 2020
3E BioventuresChinaChina1ParticipantFeb 2022
MubadalaUAEAbu Dhabi1ParticipantFeb 2022

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Dewpoint Therapeutics Competitors

Dewpoint Therapeutics competitors include listed companies like Avacta Group, Eikon Therapeutics and OmniAb, and private ones like Immvira, Biocytogen and Angiocrine Bioscience.

Public and private companies comparable to Dewpoint Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
ImmviraChinaShenzhenPrivate--$500M-
Avacta GroupUnited KingdomUnited KingdomPublicly listed$152K($38M)$495M184.3x
Eikon TherapeuticsUnited StatesUnited StatesPublicly listed-($315M)$465M-
BiocytogenChinaBeijingPrivate--$425M-
OmniAbUnited StatesUnited StatesPublicly listed$19M($47M)$646M20.2x
Angiocrine BioscienceUnited StatesNew York City, NYPrivate--$697M-

Dewpoint Therapeutics Public Comps

Dewpoint Therapeutics is still privately-owned, but its public comps include Pharmicell, Ever Supreme Bio Technology, Vogenx, Kamada, Boiron, Onconic Therapeutics, Contineum Therapeutics, Autolus Therapeutics, Avacta Group and Assembly Biosciences.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Pharmicell$83M$27M5.7x6.2x17.6x18.6x
Ever Supreme Bio Technology$32M$16M14.9x14.6x29.1x-
Vogenx-($1M)--(349.7x)-
Kamada$180M$37M2.5x2.3x11.9x9.2x
Boiron$577M$83M0.8x-5.3x-
Onconic Therapeutics$39M$9M11.7x-48.5x-
Contineum Therapeutics-($68M)-74.7x(3.9x)(3.7x)
Autolus Therapeutics$75M($258M)5.2x3.1x(1.5x)(1.8x)

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Common questions about Dewpoint Therapeutics

When was Dewpoint Therapeutics founded?Dewpoint Therapeutics was founded in 2018.
Where is Dewpoint Therapeutics headquartered?Dewpoint Therapeutics is headquartered in Boston, MA, United States.
Is Dewpoint Therapeutics publicly listed?No, Dewpoint Therapeutics is a private, VC-backed company.
What is Dewpoint Therapeutics' valuation?Dewpoint Therapeutics was last valued at $504M in its Series D in September 2025.
How much funding has Dewpoint Therapeutics raised?Dewpoint Therapeutics has raised $346M across 4 funding rounds.
What was Dewpoint Therapeutics' last funding round?Dewpoint Therapeutics' last funding round was a $59M Series D in September 2025.
Who are Dewpoint Therapeutics' investors?Dewpoint Therapeutics' investors include Polaris Partners, Leaps by Bayer, Samsara BioCapital, EcoR1 Capital, Maverick Ventures, ARCH Venture Partners, General Catalyst, Bellco Capital, SoftBank Group, Alexandria Venture Investments and 6 others.
Which companies are comparable to Dewpoint Therapeutics?Companies comparable to Dewpoint Therapeutics include Immvira, Avacta Group, Eikon Therapeutics, Biocytogen, OmniAb and Angiocrine Bioscience.

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