About Disarm Therapeutics
Disarm Therapeutics is a Cambridge-headquartered biotechnology firm developing therapeutics targeting axonal injury pathways in neurodegenerative diseases. Its lead programs address multiple sclerosis, amyotrophic lateral sclerosis, glaucoma, and peripheral neuropathies via SARM1 inhibitors, with candidates advancing through preclinical and clinical stages for central, peripheral, and ocular nervous system disorders.
Founded
2016
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Licensing
Valuation
$1.4B (acquired Oct 2020)
Sectors
Disarm Therapeutics Acquisition
Disarm Therapeutics was acquired by Eli Lilly for $1.4B on 15 October 2020.
Before the acquisition Disarm Therapeutics had raised $30M across 1 funding round.
| Acquirer | Date | Type | Price |
|---|---|---|---|
| 15 Oct 2020 | Strategic M&A | $1.4B |
Disarm Therapeutics Funding History
Disarm Therapeutics has raised a total of $30M across 1 funding round.
Disarm Therapeutics funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Sep 2017 | Series A | Atlas Venture (lead); Lightstone Ventures; AbbVie | $30M | Disarm Therapeutics, a Cambridge, Massachusetts-based biotechnology company, completed a $30 million Series A financing round on September 19, 2017, led by Atlas Venture with co-investors Lightstone Ventures and AbbVie Ventures. The company was co-founded, seeded, and incubated in 2016 by Atlas Venture together with Dr. Jeffrey Milbrandt and Dr. Aaron DiAntonio of Washington University in St. Louis, with Jason Rhodes serving as co-founder, chairman, and acting CEO. Disarm operates on a semi-virtual organizational model with fewer than 10 internal staff and more than 20 external staff members. The company had licensed exclusive rights to key SARM1 discoveries from Washington University and was developing a product engine for the discovery of new SARM1 inhibitors targeting axonal degeneration. At the time of the Series A round, Disarm was preclinical, with no drugs in human testing. The company had begun active research and development in 2016 and had developed translational strategies to assess target engagement and quantify changes in axonal structure and function to support early clinical proof-of-concept generation. Disarm's initial therapeutic focus included multiple sclerosis, amyotrophic lateral sclerosis (ALS), glaucoma, and peripheral neuropathies, with the company working with leading contract research organizations having neuro-specific expertise. The startup was subsequently acquired by Eli Lilly in a deal valued at $135 million upfront plus potential milestone payments of up to $1.2 billion, representing Lilly's bet on axonal protection as a novel approach to treating neurodegenerative diseases. |
Who has invested in Disarm Therapeutics?
3 investors have backed Disarm Therapeutics across its funding rounds, including Atlas Venture, AbbVie and Lightstone Ventures.
Lead investors include Atlas Venture.
Disarm Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 1 | Participant | Sep 2017 | ||
This data is available for Pro users. Sign up to see all 3 Disarm Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialDisarm Therapeutics Competitors
Disarm Therapeutics competitors include listed companies like LB Pharmaceuticals, Sinopep, Cullinan Therapeutics and Zhejiang Jolly, and private ones like Grupo Cimed and Alzheon.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | - | ($29M) | $1.4B | - | ||
| Publicly listed | $290M | $109M | $1.4B | - | ||
| Publicly listed | - | ($242M) | $1.4B | 115.6x | ||
| Publicly listed | $453M | $126M | $1.4B | 2.7x | ||
| Private | - | - | $1.4B | - | ||
| Private | - | - | $1.3B | - |
Disarm Therapeutics Public Comps
Disarm Therapeutics is no longer listed, but its public comps include LB Pharmaceuticals, Sinopep, Cullinan Therapeutics, Zhejiang Jolly, SOTHEMA, Immatics, Omeros, ORIC Pharmaceuticals, HBM Holdings and Phibro Animal Health.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($29M) | - | - | (36.0x) | - | |||
| $290M | $109M | 5.7x | - | 15.0x | - | |||
| - | ($242M) | - | 115.6x | (4.3x) | (5.0x) | |||
| $453M | $126M | 3.1x | 2.7x | 11.2x | 10.4x | |||
| $340M | $75M | 4.3x | 4.2x | 19.6x | - | |||
| $56M | ($233M) | 16.4x | 19.2x | (3.9x) | (3.6x) | |||
| - | ($7M) | - | 15.0x | (196.0x) | - | |||
| - | ($128M) | - | - | (8.4x) | (6.4x) | |||
This data is available for Pro users. Sign up to see all Disarm Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Disarm Therapeutics
| When was Disarm Therapeutics founded? | Disarm Therapeutics was founded in 2016. |
| Where is Disarm Therapeutics headquartered? | Disarm Therapeutics is headquartered in United States. |
| Is Disarm Therapeutics publicly listed? | No, Disarm Therapeutics was acquired by Eli Lilly in October 2020. |
| Who acquired Disarm Therapeutics? | Disarm Therapeutics was acquired by Eli Lilly in October 2020. |
| How much was Disarm Therapeutics acquired for? | Disarm Therapeutics was acquired for $1.4B in October 2020. |
| How much funding has Disarm Therapeutics raised? | Disarm Therapeutics has raised $30M across 1 funding round. |
| What was Disarm Therapeutics' last funding round? | Disarm Therapeutics' last funding round was a $30M Series A in September 2017, led by Atlas Venture. |
| Who are Disarm Therapeutics' investors? | Disarm Therapeutics' investors include Lightstone Ventures, AbbVie and Atlas Venture. |
| Which companies are comparable to Disarm Therapeutics? | Companies comparable to Disarm Therapeutics include LB Pharmaceuticals, Sinopep, Cullinan Therapeutics, Zhejiang Jolly, Grupo Cimed and Alzheon. |
See companies similar to Disarm Therapeutics
Start Your
Free Trial Today
Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.




