Alzheon Valuation, Funding & Investors

Alzheon is valued at $1.3B as of September 2026.

Last Alzheon valuation

$1.3B

Undisclosed stage · Sep 2026

Last Alzheon funding round

$79M

Undisclosed stage · Sep 2026

Cumulative funding Alzheon raised

$388M

across 9 funding rounds

Key investors in Alzheon

  • Ally Bridge Group
  • Scott H. Cohen
  • Alerce Medical Technology Partners

Alzheon Overview

About Alzheon

Alzheon is a clinical-stage biopharmaceutical company developing oral small-molecule therapeutics for Alzheimer's disease and related dementias. Its pipeline includes ALZ-801, a prodrug of tramiprosate in Phase 3 trials targeting amyloid oligomers, and ALZ-901 for combination therapy. Founded in 2011 and based in Framingham, Massachusetts, Alzheon has raised over $100 million and collaborates with institutions like Brigham and Women's Hospital.


Founded

2013

HQ

United StatesBoston, MA

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Valuation

$1.3B (Sep 2026)

Alzheon Valuation

Alzheon is currently valued at $1.3B, based on its undisclosed-stage round in September 2026.

Alzheon's valuation has grown 36x from $37M at its Series A in April 2015 to $1.3B in September 2026, across 3 priced rounds.

Alzheon valuation by funding round

Alzheon valuation by funding round
DateStageValuation
Sep 2026Undisclosed stage$1.3B
Apr 2022Series D$517M
Apr 2015Series A$37M

Alzheon Funding History

Alzheon has raised a total of $388M across 9 funding rounds.

Alzheon's first fundraising round was a $3M seed round in January 2015. The most recent completed round was a $79M undisclosed-stage round in September 2026.

Alzheon funding rounds

Alzheon funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Sep 2026Undisclosed stage-$79M$1.3BAlzheon completed a $78.8 million Series F financing in September 2026. The capital supports the company’s late-stage Alzheimer’s disease development program, including completion of its pivotal Phase III clinical work and regulatory preparation for its oral candidate ALZ-801. Alzheon is a clinical-stage biopharmaceutical company based in Framingham, Massachusetts, focused on neurodegenerative disorders, especially Alzheimer’s disease. Its lead program is ALZ-801, an oral therapy designed to address amyloid-related pathology.
Jun 2024Series EAlerce Medical Technology Partners (lead)$100M-Alzheon is a clinical-stage biopharmaceutical company based in Framingham, Massachusetts, developing a broad portfolio of product candidates and diagnostic assays for patients with Alzheimer's disease and other neurodegenerative disorders. The company's lead candidate is ALZ-801 (valiltramiprosate), an oral tablet designed as a disease-modifying therapy targeting early Alzheimer's disease, specifically patients with APOE4/4 genotype who carry the highest genetic risk. ALZ-801 inhibits the formation of soluble toxic amyloid aggregates, acting upstream from all late-stage amyloid-targeting treatments, with a favorable safety profile showing no increased risk of brain vasogenic edema in over 3,000 Alzheimer's disease patients tested. In June 2024, Alzheon closed a $100 million Series E financing round led by Alerce Medical Technology Partners, bringing total equity financing to $185 million (including the $50 million Series D raised in 2022). The proceeds support completion of the pivotal Phase III APOLLOE4 trial, which enrolled 325 subjects screened from over 6,000 patients, as well as manufacturing preparations and commercialization planning for ALZ-801 as a potentially first oral disease-modifying therapy for Alzheimer's. The APOLLOE4 trial was designed as a double-blind, randomized comparison of oral valiltramiprosate to placebo over 78 weeks, supported by a $51 million grant from the National Institute on Aging, with data readout expected in third quarter 2024 and NDA submission planned for later that year, targeting potential U.S. commercial launch in 2025.
Mar 2024Undisclosed stage-$126M-Alzheon, Inc. is a clinical-stage biopharmaceutical company developing oral therapies for Alzheimer's disease and other neurodegenerative disorders, with its lead candidate ALZ-801 (valiltramiprosate) targeting amyloid pathology in APOE4 gene carriers. The company announced a $100 million Series E financing round on June 12, 2024, led by Alerce Medical Technology Partners, following a $50 million Series D in 2022, bringing total recent fundraising to $150 million. Proceeds support completion of the pivotal APOLLOE4 Phase 3 trial, which enrolled 325 APOE4/4 homozygote patients from over 6,000 screened, manufacturing, regulatory filings including a planned NDA in 2024, and commercialization preparations for a potential U.S. launch in 2025. ALZ-801 has demonstrated a favorable safety profile with no increased risk of brain edema in over 3,000 patients and aims to be the first oral disease-modifying therapy for Alzheimer's by slowing disease progression. The APOLLOE4 trial, a 78-week study focused exclusively on high-risk APOE4 homozygotes (about one million in the U.S.), completed in 2024 with topline results expected in Q3, positioning Alzheon for regulatory meetings with the FDA. The company published four new scientific papers in 2024, totaling 13, reinforcing its precision medicine approach based on genetic and biomarker data. Investor confidence reflects progress amid a resurgence in Alzheimer's funding, contrasting past failures. New board member Muneer Satter from Alerce highlighted ALZ-801's potential for cost-effective, patient-friendly treatment. Funds extend runway into 2026, supporting platform expansion to optimized molecules for broader neurodegenerative indications.
Jan 2023Seed-$2M--
Apr 2022Series D-$50M$517MAlzheon is a clinical-stage biopharmaceutical company based in Framingham, Massachusetts, developing a portfolio of product candidates for Alzheimer's disease and other neurodegenerative disorders. The company's lead program is ALZ-801 (valiltramiprosate), an oral tablet designed as a disease-modifying therapy that inhibits the formation of soluble toxic amyloid aggregates, positioned to potentially become the first oral disease-modifying therapy for Alzheimer's disease. In April 2022, Alzheon closed a Series D financing round of $50 million at a post-money valuation of $516.92 million. The company subsequently raised an additional $100 million in Series E financing in June 2024, bringing total capital raised across these two rounds to $150 million. These funds were deployed to advance the APOLLOE4 Phase 3 clinical trial evaluating ALZ-801 in early Alzheimer's disease patients, complete manufacturing preparations, and support commercialization readiness. As a clinical-stage biopharmaceutical company, Alzheon had no disclosed revenue or EBITDA at the time of the Series D round in 2022.
Sep 2020Seed-$2M-Alzheon, Inc. is a clinical-stage biopharmaceutical company developing product candidates and diagnostic assays for Alzheimer’s disease and other neurodegenerative disorders. In January 2020, Alzheon closed a funding transaction raising $7.2 million from 13 investors, issuing 359,767 shares. The company later raised $50 million in an oversubscribed Series D round in April 2022 and $100 million in Series E financing in June 2024, led by Alerce Medical Technology Partners, to advance its lead candidate ALZ-801 (valiltramiprosate), an oral tablet for early Alzheimer’s disease in APOE4/4 homozygotes.
Jun 2017Series BAlly Bridge Group (lead)$16M--
Apr 2015Series AAlly Bridge Group (lead); Scott H. Cohen$10M$37MAlzheon, Inc. is a clinical-stage biopharmaceutical company focused on brain health, memory, and aging, developing ALZ-801, an oral small molecule prodrug of tramiprosate that inhibits amyloid formation and neurotoxicity for Alzheimer’s disease. The company closed a $10 million Series A financing round on April 8, 2015, led by Ally Bridge Group with participation from other new and existing investors including Scott H. Cohen. Proceeds funded advancement of ALZ-801 toward pivotal clinical studies, building on positive Phase 1 results from March 2015 and prior Phase 3 data on tramiprosate. Forge Global reports a post-money valuation of $37.33 million for this Series A round, with a price per share of $1.37 and 8,175,303 shares outstanding. The financing supported plans to initiate a pivotal study of ALZ-801 in Alzheimer’s patients. Ally Bridge Group, a global healthcare-focused investment platform managing over $700 million in assets, brought expertise in cross-geography partnerships.
Jan 2015Seed-$3M-Alzheon is a clinical-stage biopharmaceutical company focused on brain health, memory, and aging, with headquarters in Framingham, Massachusetts. The company's lead drug candidate is ALZ-801, an oral, small molecule, first-in-class inhibitor of amyloid formation and neurotoxicity that is a prodrug of tramiprosate. ALZ-801 builds on an established safety and efficacy profile from clinical trials involving more than 2,000 patients. Alzheon announced a $10 million Series A financing round on April 8, 2015, led by Ally Bridge Group and including new and existing investors. The proceeds were designated to advance ALZ-801 toward completion of clinical and regulatory studies for initiation of a potential pivotal clinical study in Alzheimer's disease. The financing was supported by positive Phase 1 results with ALZ-801 reported in March 2015, which demonstrated favorable pharmacological properties.

Who has invested in Alzheon?

3 investors have backed Alzheon across its funding rounds, including Ally Bridge Group, Scott H. Cohen and Alerce Medical Technology Partners.

Lead investors include Alerce Medical Technology Partners and Ally Bridge Group.


Alzheon Investors

Investors in Alzheon by funding rounds participated
InvestorHQRoundsRoleFirst check
Ally Bridge GroupHong KongHong Kong2LeadApr 2015

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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples

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Alzheon Competitors

Alzheon competitors include listed companies like HBM Holdings, ORIC Pharmaceuticals, Omeros and Immatics, and private ones like Brickell Biotech and Grupo Cimed.

Public and private companies comparable to Alzheon
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
HBM HoldingsChinaChinaPublicly listed$158M$86M$1.3B5.0x
ORIC PharmaceuticalsUnited StatesUnited StatesPublicly listed-($128M)$1.3B-
OmerosUnited StatesUnited StatesPublicly listed-($7M)$1.3B15.0x
ImmaticsUnited StatesUnited StatesPublicly listed$56M($233M)$1.3B19.2x
Brickell BiotechUnited StatesMiami, FLPrivate--$1.3B-
Grupo CimedBrazilSão PauloPrivate--$1.4B-

Alzheon Public Comps

Alzheon is still privately-owned, but its public comps include HBM Holdings, ORIC Pharmaceuticals, Omeros, Immatics, Sinopep, LB Pharmaceuticals, Maze Therapeutics, Vor Biopharma, Cullinan Therapeutics and Zhejiang Jolly.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
HBM Holdings$158M$86M6.7x5.0x12.4x11.2x
ORIC Pharmaceuticals-($128M)--(8.4x)(6.4x)
Omeros-($7M)-15.0x(196.0x)-
Immatics$56M($233M)16.4x19.2x(3.9x)(3.6x)
Sinopep$290M$109M5.7x-15.0x-
LB Pharmaceuticals-($29M)--(36.0x)-
Maze Therapeutics-($140M)-66.5x(6.8x)(5.6x)
Vor Biopharma-($699M)--(1.2x)(3.6x)

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Common questions about Alzheon

When was Alzheon founded?Alzheon was founded in 2013.
Where is Alzheon headquartered?Alzheon is headquartered in Boston, MA, United States.
Is Alzheon publicly listed?No, Alzheon is a private, VC-backed company.
What is Alzheon's valuation?Alzheon was last valued at $1.3B in its undisclosed-stage round in September 2026.
How much funding has Alzheon raised?Alzheon has raised $388M across 9 funding rounds.
What was Alzheon's last funding round?Alzheon's last funding round was a $79M undisclosed-stage round in September 2026.
Who are Alzheon's investors?Alzheon's investors include Ally Bridge Group, Alerce Medical Technology Partners and Scott H. Cohen.
Which companies are comparable to Alzheon?Companies comparable to Alzheon include HBM Holdings, ORIC Pharmaceuticals, Omeros, Immatics, Brickell Biotech and Grupo Cimed.

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