Calyxo Valuation, Funding & Investors

Eko Health is an Emeryville-headquartered digital health firm developing FDA-cleared stethoscopes, telehealth software, and AI algorithms for cardiac and pulmonary disease detection. Its devices, like the CORE 500 and DUO ECG, integrate with electronic health records and are deployed in clinics, hospitals, and telemedicine across the United States and Europe, backed by partnerships with Mayo Clinic and Sutter Health.

Myriad Genetics Inc is a molecular diagnostics and precision medicine company committed to advancing health and well-being for all. The company develops and commercializes molecular tests that help patients and providers uncover genetic insights. Its tests assess the risk of developing disease or disease progression and guide treatment decisions across medical specialties, supporting earlier detection, more precise treatment, and lowering healthcare costs. Its tests include BRACAnalysis CDx, EndoPredict, FirstGene, Foresight, GeneSight, MyChoice CDx, MyRisk (cancer treatment), MyRisk (cancer risk), Prequel, Precise Tumor, Prolaris, and SneakPeek. The company operates in the US and Rest of World, with maximum revenue from the US.

LightForce Orthodontics makes a fully personalized, 3D-printed braces system that uses AI and digital workflows to design custom brackets for each patient's anatomy. Orthodontists use the platform for treatment planning, from intraoral scans through final prescriptions, aiming to shorten treatment timelines and reduce the number of patient visits compared with standard orthodontics. The company manufactures its brackets in the United States, including at a facility in Wilmington, Massachusetts.

TytoCare is a Tel Aviv-headquartered digital health company offering remote examination devices and telehealth platforms. TytoHome enables consumer self-exams of heart, lungs, skin, throat, ears, and temperature, while TytoPro supports clinicians and TytoClinic serves clinics. The system includes AI-guided tools, video consultations, and cloud analytics, used by over 1,000 healthcare organizations globally.

InSightec is a Haifa-based pioneer in magnetic resonance-guided focused ultrasound for non-invasive surgeries. The Exablate Neuro system treats essential tremor and Parkinsonian tremor, earning FDA approval in 2016 after initial uterine fibroid clearance in 2004. InSightec's technology also addresses bone metastases pain and adenomyosis, with installations in over 100 centers globally including Mayo Clinic and University of Toronto.

Shoulder Innovations Inc is a commercial-stage medical technology company exclusively focused on transforming the shoulder surgical care market. It currently offers advanced implant systems for shoulder arthroplasty. Its products include: InSet Total Shoulder Arthroplasty; InSet Reverse Shoulder Arthroplasty; ProVoyance Shoulder Planning Software; and InSet Tray System.

Reprieve Cardiovascular is a Minnetonka-headquartered medical device company developing fluid management systems for congestive heart failure. Its Reprieve technology enables precise ultrafiltration during dialysis to decongest acute decompensated patients. As a subsidiary of CardioRenal Systems, it advances clinical trials for cardiac care integration.

Nanjing Medlander Medical Technology Co Ltd is engaged in the research and development, production, sales, and service of related products in the field of pelvic floor and postpartum rehabilitation. Its products mainly include: biostimulation feedback instrument, color ultrasound diagnosis and evaluation system, magnetic stimulator, high-frequency evaluation electrocautery instrument, pelvic floor training instrument, portable postpartum recovery instrument, home pelvic floor rehabilitation therapy instrument, etc., which are widely used in obstetrics and gynecology, pelvic floor rehabilitation center, urology, anorectal department and other hospital departments.

Carlsmed Inc is a commercial-stage medical technology company pioneering AI-enabled personalized spine surgery solutions with a mission to improve outcomes and decrease the cost of healthcare for spine surgery and beyond. It is focused on becoming the standard of care for spine fusion surgery. The aprevo Technology Platform consists of AI-enabled software solutions, and interbody implants that it custom design for each patient's unique pathology and vertebral bone topography, and single-use surgical instruments. The Company designs, manufactures, and markets aprevo, a comprehensive technology platform for spine fusion surgery procedures.

Tasso is a Seattle-based medical device company pioneering at-home blood collection for diagnostics. Its HemoLink device enables capillary blood sampling with 200 microliters yield in under 3 minutes, compatible with lab analyzers for therapeutic drug monitoring and wellness testing. FDA-cleared since 2020, Tasso partners with Quest Diagnostics and Everlywell, shipping over 50,000 units to consumers and clinics. Founded in 2015, the firm raised $15 million in Series A funding and operates in the US with clinical trials in Europe for chronic disease management.

Genalyte is a San Diego-headquartered life sciences company commercializing the Maverick platform for multiplexed protein and nucleic acid detection using silicon photonics. The technology enables rapid, chip-based immunoassays measuring dozens of biomarkers from a single blood sample in minutes. Genalyte targets autoimmune, infectious disease, and cardiology diagnostics, with FDA-cleared tests for rheumatoid arthritis and lupus markers.