Arkuda Therapeutics Valuation, Funding & Investors

Arkuda Therapeutics is valued at $134M as of February 2022.

Last Arkuda Therapeutics valuation

$134M

Series B · Feb 2022

Last Arkuda Therapeutics funding round

$64M

Series B · Feb 2022

Cumulative funding Arkuda Therapeutics raised

$108M

across 2 funding rounds

Key investors in Arkuda Therapeutics

  • Atlas Venture
  • Pfizer Venture Investments
  • Mission BioCapital
  • Tekla Capital Management
  • Cormorant Asset Management
  • Eli Lilly

Arkuda Therapeutics Overview

About Arkuda Therapeutics

Arkuda Therapeutics is a Boston-based biotechnology firm developing therapies for frontotemporal dementia caused by GRN mutations. Its lead candidates restore progranulin levels to address lysosomal dysfunction, advancing through Phase 1 trials with oral small molecules. Founded in 2020, Arkuda collaborates with academic centers on neurodegenerative biomarkers, positioning as a specialist in genetic FTD subtypes.


Founded

2018

HQ

United StatesUnited States

Status

Privately held

Customer focus

B2B

Revenue model

Licensing

Valuation

$134M (Feb 2022)

Arkuda Therapeutics Valuation

Arkuda Therapeutics is currently valued at $134M, based on its Series B in February 2022.

The $64M round was led by Cormorant Asset Management and Pivotal bioVenture Partners, with participation from Pfizer Venture Investments, Atlas Venture, Tekla Capital Management, Eli Lilly, Mission BioCapital and 1 other investor.

Arkuda Therapeutics valuation by funding round

Arkuda Therapeutics valuation by funding round
DateStageValuation
Feb 2022Series B$134M

Arkuda Therapeutics Funding History

Arkuda Therapeutics has raised a total of $108M across 2 funding rounds.

Arkuda Therapeutics' first fundraising round was a $44M Series A in November 2019. The most recent completed round was a $64M Series B in February 2022.

Arkuda Therapeutics funding rounds

Arkuda Therapeutics funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Feb 2022Series BCormorant Asset Management (lead); Pivotal bioVenture Partners (lead); Pfizer Venture Investments; Atlas Venture; Tekla Capital Management; Eli Lilly; Mission BioCapital; Surveyor Capital$64M$134MArkuda Therapeutics is a biotechnology company developing medicines to alter the trajectory of neurodegenerative diseases, with a focus on lysosomal biology and its lead progranulin enhancer program advancing into IND-enabling studies. On February 10, 2022, the company raised $64 million in an oversubscribed Series B financing round, co-led by Cormorant Asset Management and Pivotal bioVenture Partners, with participation from Surveyor Capital (a Citadel company), Eli Lilly and Company, and existing investors Atlas Venture, Pfizer Venture Investments, Tekla Capital Management, and Mission BioCapital. This brought total funding to $108 million across three rounds, including a prior Series A and seed. The proceeds from the Series B are designated to support progression of the lead program into IND-enabling studies and to advance the pipeline targeting lysosomal biology for neurodegenerative diseases. Arkuda operates in the competitive neurodegenerative disease space, leveraging innovative approaches to lysosomal function. The investor syndicate includes prominent venture capital, asset management, and corporate venture arms from pharma giants like Pfizer and Eli Lilly, signaling strong backing for its preclinical pipeline.
Nov 2019Series AAtlas Venture (lead); Pfizer Venture Investments (lead); Tekla Capital Management; Mission BioCapital$44M-Arkuda Therapeutics is a biotechnology company focused on developing small-molecule therapies targeting progranulin and lysosomal biology to treat neurodegenerative diseases, particularly GRN-related frontotemporal dementia (FTD-GRN), a genetically defined subtype caused by mutations in the GRN gene leading to progranulin deficiency and lysosomal dysfunction. The company was founded in 2018 by Atlas Venture, Gerhard Koenig, and Duane Burnett, and officially launched in November 2019 with a $44 million Series A financing co-led by Atlas Venture and Pfizer Ventures, with participation from funds managed by Tekla Capital Management and BioInnovation Capital. The company, based in Cambridge, Massachusetts, was seeded and incubated by Atlas Venture prior to launch. Arkuda's lead approach aims to boost progranulin levels in the central nervous system to improve lysosomal function and neuronal health, validated in preclinical models. This round, announced on November 7, 2019, supports advancing preclinical programs toward clinical trials, with plans to initiate a Phase 1b proof-of-mechanism study in humans by 2021. Investors highlighted the team's expertise in CNS disorders and neurodegeneration. In a later development, Arkuda raised a $64 million Series B in February 2022 from Atlas Venture, Cormorant Asset Management, Eli Lilly and Company, Mission BioCapital, Pfizer Ventures, Pivotal bioVenture Partners, Surveyor Capital, and Tekla Capital Management to further its pipeline. Arkuda continues exploring progranulin modulation for additional indications like Alzheimer's and Parkinson's.

Who has invested in Arkuda Therapeutics?

8 investors have backed Arkuda Therapeutics across its funding rounds, including Atlas Venture, Pfizer Venture Investments, Mission BioCapital, Tekla Capital Management, Cormorant Asset Management and Eli Lilly.

Lead investors include Cormorant Asset Management, Pivotal bioVenture Partners, Atlas Venture and Pfizer Venture Investments.


Arkuda Therapeutics Investors

Investors in Arkuda Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Pfizer Venture InvestmentsUnited StatesNew York City, NY2LeadNov 2019
Atlas VentureUnited StatesUnited States2LeadNov 2019
Tekla Capital ManagementUnited StatesBoston, MA2ParticipantNov 2019
Mission BioCapitalUnited StatesUnited States2ParticipantNov 2019
Eli LillyUnited StatesIndianapolis, IN1ParticipantFeb 2022
Pivotal bioVenture PartnersUnited StatesSan Francisco, CA1LeadFeb 2022

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Arkuda Therapeutics Competitors

Arkuda Therapeutics competitors include listed companies like Cellectis, Z Squared, Orthocell and Unicycive, and private ones like Teewinot Life Sciences and Spur Therapeutics.

Public and private companies comparable to Arkuda Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
CellectisFranceFrancePublicly listed$73M($49M)$134M0.8x
Z SquaredUnited StatesUnited StatesPublicly listed-($0K)$135M-
OrthocellAustraliaAustraliaPublicly listed$8M($11M)$135M11.0x
UnicyciveUnited StatesUnited StatesPublicly listed-($27M)$133M74.1x
Teewinot Life SciencesUnited StatesTampa, FLPrivate--$138M-
Spur TherapeuticsUnited KingdomStevenagePrivate--$139M-

Arkuda Therapeutics Public Comps

Arkuda Therapeutics is still privately-owned, but its public comps include Cellectis, Z Squared, Orthocell, Unicycive, TuHURA Biosciences, ADC Therapeutics, Hyloris Pharmaceuticals, Heidelberg Pharma, Biosyent and LENZ Therapeutics.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Cellectis$73M($49M)0.7x0.8x(1.0x)(0.8x)
Z Squared-($0K)--(1985476.0x)-
Orthocell$8M($11M)12.8x11.0x(9.7x)(11.5x)
Unicycive-($27M)-74.1x(2.7x)-
TuHURA Biosciences-($29M)--(4.8x)-
ADC Therapeutics$81M($97M)0.4x0.4x(0.3x)(0.3x)
Hyloris Pharmaceuticals$8M($7M)14.8x9.3x(17.8x)(9.5x)
Heidelberg Pharma$2M($45M)64.8x13.6x(2.4x)-

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Common questions about Arkuda Therapeutics

When was Arkuda Therapeutics founded?Arkuda Therapeutics was founded in 2018.
Where is Arkuda Therapeutics headquartered?Arkuda Therapeutics is headquartered in United States.
Is Arkuda Therapeutics publicly listed?No, Arkuda Therapeutics is a private, VC-backed company.
What is Arkuda Therapeutics' valuation?Arkuda Therapeutics was last valued at $134M in its Series B in February 2022.
How much funding has Arkuda Therapeutics raised?Arkuda Therapeutics has raised $108M across 2 funding rounds.
What was Arkuda Therapeutics' last funding round?Arkuda Therapeutics' last funding round was a $64M Series B in February 2022, led by Cormorant Asset Management and Pivotal bioVenture Partners.
Who are Arkuda Therapeutics' investors?Arkuda Therapeutics' investors include Pfizer Venture Investments, Atlas Venture, Tekla Capital Management, Mission BioCapital, Eli Lilly, Pivotal bioVenture Partners, Cormorant Asset Management and Surveyor Capital.
Which companies are comparable to Arkuda Therapeutics?Companies comparable to Arkuda Therapeutics include Cellectis, Z Squared, Orthocell, Unicycive, Teewinot Life Sciences and Spur Therapeutics.

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