Ambience Healthcare Revenue, Valuation, Funding & Investors

Ambience Healthcare is valued at $1.3B as of July 2025, a 32.9x multiple on its last reported $38M revenue.

Last Ambience Healthcare valuation

$1.3B

Series C · Jul 2025

Last Ambience Healthcare funding round

$243M

Series C · Jul 2025

Ambience Healthcare revenue

$38M

Series C · Jul 2025

Key investors in Ambience Healthcare

  • Andreessen Horowitz
  • Kleiner Perkins
  • Optum Ventures
  • OpenAI Startup Fund
  • 500 Global
  • Oak HC/FT

Ambience Healthcare Overview

About Ambience Healthcare

Ambience Healthcare is a San Francisco-headquartered developer of an AI-powered operating system for clinical documentation and workflows. Its AutoScribe captures patient conversations via ambient microphones, generating SOAP notes, billing codes, and orders in under 10 seconds with 95% accuracy. Integrated with Epic, Cerner, and Athenahealth EMRs, the platform serves 2,000 providers across 500 clinics, reducing documentation time by 75% and raising $70 million in Series B funding in 2023.


Founded

2020

HQ

United StatesSan Francisco, CA

Status

Privately held

Customer focus

B2B

Revenue model

Subscription

Revenue

$38M (Jul 2025)

Valuation

$1.3B (Jul 2025)

Ambience Healthcare Valuation

Ambience Healthcare is currently valued at $1.3B, based on its Series C in July 2025.

The $243M round was led by Andreessen Horowitz and Oak HC/FT, with participation from OpenAI Startup Fund, Smash Capital, Frist Cressey Ventures, Kleiner Perkins, Town Hall Ventures and 3 other investors.

Ambience Healthcare valuation by funding round

Ambience Healthcare valuation by funding round
DateStageValuationRevenue Multiple
Jul 2025Series C$1.3B32.9x

Ambience Healthcare Revenue

Ambience Healthcare's latest recorded revenue is $38M, as of its Series C in July 2025. At a $1.3B valuation, that implies a 32.9x revenue multiple.

Ambience Healthcare revenue by funding round

Ambience Healthcare revenue and valuation multiple by funding round
DateRevenue *ValuationRevenue MultipleStage
Jul 2025$38M$1.3B32.9xSeries C

* Revenue (or ARR) figures are the values recorded alongside each funding round. Typically run-rate revenue at the time of the deal, or a reported LTM (last 12 months) revenue.

Ambience Healthcare Funding History

Ambience Healthcare has raised a total of $319M across 3 funding rounds.

Ambience Healthcare's first fundraising round was a $6M seed round in September 2020. The most recent completed round was a $243M Series C in July 2025.

Ambience Healthcare funding rounds

Ambience Healthcare funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Jul 2025Series CAndreessen Horowitz (lead); Oak HC/FT (lead); OpenAI Startup Fund; Smash Capital; Frist Cressey Ventures; Kleiner Perkins; Town Hall Ventures; Georgian; Founders Circle Capital; Optum Ventures$243M$1.3BAmbience Healthcare is a San Francisco-based artificial intelligence platform founded in 2020 by Mike Ng and Nikhil Buduma that automates clinical documentation, medical coding, and clinical documentation integrity (CDI) for healthcare providers. The platform serves as an ambient AI scribe that reduces administrative burden on physicians and nurses by handling documentation and workflow optimization across outpatient clinics, emergency departments, and inpatient hospital settings. It integrates directly with major electronic health record systems including Epic, Oracle Cerner, and athenahealth. In July 2025, Ambience Healthcare announced a $243 million Series C funding round co-led by Oak HC/FT and Andreessen Horowitz, with participation from existing investors OpenAI Startup Fund, Kleiner Perkins, and Optum Ventures, as well as new investors Frist Cressey Ventures, Town Hall Ventures, Smash Capital, Georgian, and Founders Circle Capital. The funding round valued the company at $1.25 billion, achieving unicorn status. To date, Ambience has raised approximately $345 million across all rounds. The company is deployed at leading U.S. health systems including Cleveland Clinic, UCSF Health, Houston Methodist, and Memorial Hermann, supporting more than 100 ambulatory subspecialties, emergency departments, and inpatient specialties. Ambience achieved a 97.7 customer satisfaction score in recent KLAS evaluations and is the first ambient documentation solution with third-party validated, CFO-approved return on investment tied to improved coding accuracy and compliance. The Series C funding will support expansion to additional healthcare organizations, product development acceleration, and broader deployment across the continuum of care.
Feb 2024Series BKleiner Perkins (lead); OpenAI Startup Fund (lead); Andreessen Horowitz; Optum Ventures; 500 Global$70M-Ambience Healthcare, founded in 2020 by Mike Ng and Nikhil Buduma and headquartered in San Francisco, develops the most comprehensive AI operating system for healthcare organizations, focusing on ambient AI tools like AutoScribe for real-time medical scribing and AutoCDI for coding accuracy to reduce clinician burnout, improve efficiency, and enhance revenue cycle performance. The company announced a $70M Series B funding round on February 6, 2024, co-led by Kleiner Perkins and OpenAI Startup Fund, with participation from existing investors Andreessen Horowitz and Optum Ventures, bringing total funding to $100M. The funding aims to scale product roadmap, expand teams, advance AI models for healthcare, and support deployments with major organizations including UCSF, Memorial Hermann Health System, John Muir Health, The Oncology Institute, GI Alliance, Midi Health, and Eventus WholeHealth. Ambience integrates seamlessly with EMRs like Epic, Cerner, eClinicalWorks, Athenahealth, Elation, and AdvancedMD, driving growth through rapid clinician adoption and financial ROI for health systems. The platform targets ambulatory specialties like cardiology, oncology, pediatrics, and ENT, operating in a competitive nascent market of medical AI co-pilots that had raised over $415M by early 2024. A subsequent $243M Series C in July 2025 was co-led by Oak HC/FT and Andreessen Horowitz, with Kleiner Perkins, OpenAI Startup Fund, and Optum Ventures participating, expanding to documentation, coding, CDI across 100+ subspecialties, EDs, and inpatient care for clients like Cleveland Clinic and Houston Methodist.
Sep 2020Seed-$6M-By May 2025, Ambience had achieved $30M in ARR, up from $19M at the end of 2024.

Who has invested in Ambience Healthcare?

11 investors have backed Ambience Healthcare across its funding rounds, including Andreessen Horowitz, Kleiner Perkins, Optum Ventures, OpenAI Startup Fund, 500 Global and Oak HC/FT.

Lead investors include Andreessen Horowitz, Oak HC/FT, Kleiner Perkins and OpenAI Startup Fund.


Ambience Healthcare Investors

Investors in Ambience Healthcare by funding rounds participated
InvestorHQRoundsRoleFirst check
OpenAI Startup FundUnited StatesSan Francisco, CA2LeadFeb 2024
Kleiner PerkinsUnited StatesSan Francisco, CA2LeadFeb 2024
Andreessen HorowitzUnited StatesSan Francisco, CA2LeadFeb 2024
Optum VenturesUnited StatesBoston, MA2ParticipantFeb 2024
Smash CapitalUnited StatesLos Angeles, CA1ParticipantJul 2025
Frist Cressey VenturesUnited StatesNashville, TN1ParticipantJul 2025
Town Hall VenturesUnited StatesNew York City, NY1ParticipantJul 2025
GeorgianCanadaToronto1ParticipantJul 2025
Founders Circle CapitalUnited StatesSan Francisco, CA1ParticipantJul 2025

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Ambience Healthcare Competitors

Ambience Healthcare competitors include listed companies like U.S. Physical Therapy and EverCommerce, and private ones like Cadence Solutions, Viz, MasterControl and AgentSync.

Public and private companies comparable to Ambience Healthcare
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
U.S. Physical TherapyUnited StatesUnited StatesPublicly listed$781M$110M$1.2B2.3x
Cadence SolutionsUnited StatesNew York City, NYPrivate$35M-$1.2B-
VizUnited StatesUnited StatesPrivate$100M-$1.3B12.8x
MasterControlUnited StatesSalt Lake City, UTPrivate$100M-$1.3B13.0x
AgentSyncUnited StatesDenver, COPrivate$11M-$1.2B109.1x
EverCommerceUnited StatesUnited StatesPublicly listed$589M$128M$1.4B2.9x

Ambience Healthcare Public Comps

Ambience Healthcare is still privately-owned, but its public comps include U.S. Physical Therapy, EverCommerce, PHC Holdings, Vitec Software, iFLYHealth, Indegene, Omnicell, HealthStream, MedicalSystem Technology and Hangzhou Pinming Software.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
U.S. Physical Therapy$781M$110M2.5x2.3x17.5x18.9x
EverCommerce$589M$128M3.0x2.9x13.7x9.5x
PHC Holdings$2.3B$320M1.0x1.0x7.2x6.5x
Vitec Software$371M$151M3.7x3.5x9.1x9.0x
iFLYHealth$136M($7M)7.7x6.2x(150.8x)(144172.5x)
Indegene$366M$68M3.7x3.3x19.9x18.2x
Omnicell$1.2B$92M1.2x1.1x15.0x8.1x
HealthStream$304M$63M2.8x2.6x13.2x11.2x

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Common questions about Ambience Healthcare

When was Ambience Healthcare founded?Ambience Healthcare was founded in 2020.
Where is Ambience Healthcare headquartered?Ambience Healthcare is headquartered in San Francisco, CA, United States.
Is Ambience Healthcare publicly listed?No, Ambience Healthcare is a private, VC-backed company.
What is Ambience Healthcare's valuation?Ambience Healthcare was last valued at $1.3B in its Series C in July 2025.
How much funding has Ambience Healthcare raised?Ambience Healthcare has raised $319M across 3 funding rounds.
What was Ambience Healthcare's last funding round?Ambience Healthcare's last funding round was a $243M Series C in July 2025, led by Andreessen Horowitz and Oak HC/FT.
Who are Ambience Healthcare's investors?Ambience Healthcare's investors include OpenAI Startup Fund, Kleiner Perkins, Andreessen Horowitz, Optum Ventures, Smash Capital, Frist Cressey Ventures, Town Hall Ventures, Georgian, Founders Circle Capital, Oak HC/FT and 1 other.
What is Ambience Healthcare's revenue?Ambience Healthcare's latest recorded revenue is $38M (July 2025).
What is Ambience Healthcare's revenue multiple?Ambience Healthcare's latest valuation implies a 32.9x revenue multiple ($1.3B valuation on $38M of revenue).
Which companies are comparable to Ambience Healthcare?Companies comparable to Ambience Healthcare include U.S. Physical Therapy, Cadence Solutions, Viz, MasterControl, AgentSync and EverCommerce.

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