About Vicebio
ViceBio is a Sydney-headquartered clinical-stage biopharmaceutical company engineering vaccines with Molecular Clamp technology for respiratory pathogens like RSV and parainfluenza. Its multipathogen candidates deliver broad-spectrum protection in stable, needle-free formats suitable for global distribution. Supported by CEPI funding, ViceBio advances Phase 1 trials targeting infants and elderly populations in Australia and Europe.
Founded
2019
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Licensing
Valuation
$1.6B (acquired Jul 2025)
Sectors
Vicebio Acquisition
Vicebio was acquired by Sanofi for $1.6B on 22 July 2025.
Before the acquisition Vicebio had raised $100M across 1 funding round.
Vicebio Ltd, a London-headquartered biopharmaceutical company, develops novel vaccines against life-threatening respiratory viral infections using its proprietary ‘Molecular Clamp’ technology, which stabilizes viral proteins in their native shape to enhance immune recognition, enable fully liquid combination vaccines stable at 2–8°C refrigeration, and simplify manufacturing in prefilled syringes. Sanofi, a global pharmaceutical leader with established respiratory vaccines like the approved RSV antibody Beyfortus (generating $1.77 billion in prior-year sales), acquired Vicebio to expand its respiratory vaccines pipeline with Vicebio’s lead asset VXB-241, an early-stage bivalent vaccine candidate targeting respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) that recently completed a Phase 1b study in over 150 healthy volunteers. This non-mRNA protein-based combination vaccine complements Sanofi’s portfolio, offering additional physician and patient choices amid growing demand for respiratory protections. Sanofi announced the definitive agreement on July 22, 2025, to purchase all of Vicebio’s share capital for an upfront payment of $1.15 billion plus up to $450 million in development and regulatory milestone payments, totaling a potential $1.6 billion. The deal closed on December 4, 2025, after satisfying customary conditions including regulatory approvals, with no material impact on Sanofi’s 2025 financial guidance. Strategic rationale centers on leveraging Vicebio’s Molecular Clamp platform—originating from University of Queensland collaborations and backed by investors like Medicxi—for accelerated development of next-generation multivalent vaccines against respiratory pathogens and beyond, aligning with Sanofi’s recent respiratory investments such as the May 2024 Novavax COVID-19 vaccine licensing deal worth up to $1.4 billion and ongoing large-cap biopharma M&A trends in the sector.
| Acquirer | Date | Type | Price |
|---|---|---|---|
| 22 Jul 2025 | Strategic M&A | $1.6B |
Vicebio Funding History
Vicebio has raised a total of $100M across 1 funding round.
Vicebio funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Sep 2024 | Series B | TCG Crossover (lead); Avoro Ventures; UniQuest; venBio Partners; Goldman Sachs Asset Management; Medicxi | $100M | Vicebio is a biopharmaceutical company developing novel vaccines against life-threatening respiratory viral infections using its proprietary Molecular Clamp technology. The company announced a $100 million Series B financing on September 23, 2024, led by TCG Crossover (TCGX), with investments from Goldman Sachs Alternatives, Avoro Ventures, venBio Partners, and participation from UniQuest and founding investor Medicxi. This funding enables acceleration of clinical development for lead asset VXB-241, a bivalent vaccine targeting RSV and hMPV in elderly and immunocompromised patients, and expansion of the multivalent pipeline including VXB-251, a trivalent vaccine adding Parainfluenza Virus 3 (PIV3). Vicebio had initiated an exploratory Phase 1 clinical trial for VXB-241, with interim data showing a favorable safety and tolerability profile in adults aged 60 and above. The Series B round underscores investor confidence in Vicebio's platform, which aims to deliver next-generation multivalent vaccines addressing significant medical burdens in respiratory diseases. Subsequently, on July 22, 2025, Vicebio entered an agreement to be acquired by Sanofi for up to $1.6 billion, including a $1.15 billion upfront payment and up to $450 million in milestones, providing Sanofi access to the Molecular Clamp technology and the respiratory vaccine pipeline. |
Who has invested in Vicebio?
6 investors have backed Vicebio across its funding rounds, including Goldman Sachs Asset Management, venBio Partners, Medicxi, TCG Crossover, UniQuest and Avoro Ventures.
Lead investors include TCG Crossover.
Vicebio Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 1 | Lead | Sep 2024 | ||
| 1 | Participant | Sep 2024 | ||
| 1 | Participant | Sep 2024 | ||
| 1 | Participant | Sep 2024 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialVicebio Competitors
Vicebio competitors include listed companies like Idorsia, Concord Biotech, InventisBio and Absci, and private ones like Pathos and Brise Pharma.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Private | $13M | $3M | $1.6B | 123.1x | ||
| Publicly listed | $268M | ($55M) | $1.6B | 11.7x | ||
| Publicly listed | $109M | $43M | $1.6B | 12.7x | ||
| Publicly listed | $6M | ($49M) | $1.6B | 92.6x | ||
| Publicly listed | $3M | ($103M) | $1.6B | 388.4x | ||
| Private | - | - | $1.6B | - |
Vicebio Public Comps
Vicebio is no longer listed, but its public comps include Idorsia, Concord Biotech, InventisBio, Absci, Latigo Biotherapeutics, AnaptysBio, Syndax, Hualan Biological Vaccine, Eton Pharmaceuticals and Forte Biosciences.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $268M | ($55M) | 11.6x | 11.7x | (56.1x) | (51.1x) | |||
| $109M | $43M | 14.2x | 12.7x | 35.7x | 35.6x | |||
| $6M | ($49M) | 254.6x | 92.6x | (29.1x) | (32.7x) | |||
| $3M | ($103M) | 496.8x | 388.4x | (13.5x) | (11.9x) | |||
| - | ($112M) | - | - | (16.6x) | - | |||
| $235M | $56M | 5.8x | 10.1x | 24.2x | 34.4x | |||
| $172M | ($274M) | 9.4x | 5.9x | (5.9x) | (8.6x) | |||
| $179M | $49M | 7.3x | 6.6x | 26.8x | 28.6x | |||
This data is available for Pro users. Sign up to see all Vicebio competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Vicebio
| When was Vicebio founded? | Vicebio was founded in 2019. |
| Where is Vicebio headquartered? | Vicebio is headquartered in London, United Kingdom. |
| Is Vicebio publicly listed? | No, Vicebio was acquired by Sanofi in July 2025. |
| Who acquired Vicebio? | Vicebio was acquired by Sanofi in July 2025. |
| How much was Vicebio acquired for? | Vicebio was acquired for $1.6B in July 2025. |
| How much funding has Vicebio raised? | Vicebio has raised $100M across 1 funding round. |
| What was Vicebio's last funding round? | Vicebio's last funding round was a $100M Series B in September 2024, led by TCG Crossover. |
| Who are Vicebio's investors? | Vicebio's investors include TCG Crossover, Avoro Ventures, UniQuest, venBio Partners, Goldman Sachs Asset Management and Medicxi. |
| Which companies are comparable to Vicebio? | Companies comparable to Vicebio include Pathos, Idorsia, Concord Biotech, InventisBio, Absci and Brise Pharma. |
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