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- Vedanta Biosciences
Vedanta Biosciences Valuation, Funding & Investors
Vedanta Biosciences is valued at $287M as of July 2021.
Last Vedanta Biosciences valuation
$287M
Series D · Jul 2021
Last Vedanta Biosciences funding round
$40M
Undisclosed stage · Aug 2026
Cumulative funding Vedanta Biosciences raised
$370M
across 8 funding rounds
Key investors in Vedanta Biosciences
Rock Springs Capital
PureTech Health
Partners Investment
Bristol-Myers Squibb
Bill & Melinda Gates Foundation
JSR
About Vedanta Biosciences
Vedanta Biosciences is a Cambridge, Massachusetts-based biotechnology company engineering microbiome immunotherapies for autoimmune, inflammatory, and infectious diseases. It develops consortia of live bacteria selected via proprietary assays from human donor samples, manufactured in cGMP facilities for oral administration. Vedanta's lead candidate VE202 advances in Phase 2 for graft-versus-host disease, with prior programs partnered to Janssen for Crohn's disease. Founded in 2010 as Seres spin-out, it maintains a library of over 1,000 bacterial strains and datasets from interventional studies.
Founded
2010
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Valuation
$287M (Jul 2021)
Vedanta Biosciences Valuation
Vedanta Biosciences is currently valued at $287M, based on its Series D in July 2021.
The $68M round was led by Magnetar Capital, with participation from Shumway Capital, Skyviews Life Science, Verition Fund Management, Rock Springs Capital, JSR and 3 other investors.
Vedanta Biosciences valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Jul 2021 | Series D | $287M |
Vedanta Biosciences Funding History
Vedanta Biosciences has raised a total of $370M across 8 funding rounds.
Vedanta Biosciences' first fundraising round was a $50M undisclosed-stage round in June 2016. The most recent completed round was a $40M undisclosed-stage round in August 2026.
Vedanta Biosciences funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Aug 2026 | Undisclosed stage | AMR Action Fund (lead); BNP Paribas Asset Management (lead) | $40M | - | Vedanta Biosciences secured $60 million in new financing on August 6, 2026, consisting of a $40 million equity financing led by existing investors AMR Action Fund and BNP Paribas Asset Management Alts, plus an additional $20 million from BARDA under an existing contract. The capital is being used to support the pivotal Phase 3 RESTORATiVE303 study of VE303 for prevention of recurrent C. difficile infection, with topline efficacy data expected in 1H 2027. The financing extends Vedanta’s runway for late-stage development of its microbiome-based oral therapies and comes alongside board and leadership additions. The company is a late clinical-stage biopharmaceutical firm based in Cambridge, Massachusetts, focused on defined bacterial consortia therapies for gastrointestinal diseases and has advanced VE303 as its lead candidate. The announcement emphasizes continued support from existing investors and BARDA to carry the program through its next clinical milestone. |
| Apr 2023 | Series E | AMR Action Fund (lead); AXA Investment Managers (lead) | $107M | - | Vedanta Biosciences is a clinical-stage biopharmaceutical company developing oral therapies based on defined bacterial consortia to restore gut microbiome balance for conditions like recurrent Clostridioides difficile infection (CDI), ulcerative colitis, and malnutrition. Its lead candidate, VE303, targets prevention of recurrent CDI, classified as an urgent threat by the CDC, with approximately 500,000 U.S. cases yearly causing tens of thousands of deaths. Positive Phase 2 results for VE303 reported in October 2021 triggered a $23.8 million BARDA contract option, part of up to $81.9 million federal funding for Phase 3 support. In April 2023, Vedanta raised $106.5 million in financing co-led by new investors AMR Action Fund and AXA IM Alts ($25 million from AXA), with participation from existing investors including Bill & Melinda Gates Foundation, Skyviews Life Science, Reimagined Ventures, Fiscus Ventures, PEAK6, Atlantic Neptune, PureTech Health, Revelation Partners, QUAD Investment Management, Seventure Partners, Hambro Perks, and Pfizer, plus new investors K2 HealthVentures and Korea Investment entities. Funds will support a pivotal Phase 3 trial of VE303 starting by Q3 2023, Phase 2 study of VE202 for ulcerative colitis starting Q2 2023, and other development. New board members include Curt LaBelle from AXA IM Alts, Martin Heidecker, and Neil Tiwari. The financing advances Vedanta's patent-protected platform for identifying, manufacturing, and formulating key bacteria into stable oral capsules, addressing infectious diseases and malnutrition aligned with UN Sustainable Development Goal 5. |
| Jul 2021 | Series D | Magnetar Capital (lead); Shumway Capital; Skyviews Life Science; Verition Fund Management; Rock Springs Capital; JSR; SymBiosis LLC; Health for Life Capital fund; PureTech Health | $68M | $287M | Vedanta Biosciences is a clinical-stage microbiome therapeutics company developing oral therapies based on defined bacterial consortia to treat diseases like recurrent Clostridioides difficile infection (CDI) and ulcerative colitis. In July 2021, it completed a $68 million Series D financing led by affiliates of Magnetar Capital, with participation from Verition Fund Management, Fosun Health Capital (noted as Health for Life Capital in some sources), PureTech Health, Rock Springs Capital, Skyviews Life Science, JSR Corporation, SymBiosis LLC, Shumway Capital, and a $25 million investment from Pfizer under its Breakthrough Growth Initiative. The proceeds were allocated to advance its pipeline, including a Phase 3 trial of VE303 for high-risk recurrent CDI patients and a Phase 2 trial of VE202 for mild to moderate ulcerative colitis. The company had previously received up to $76.9 million in federal funding from the Department of Health and Human Services in 2020 and a $25 million Pfizer investment announced in January 2021. Later, in 2023, Vedanta raised a $106.5 million financing co-led by AXA IM Alts and The AMR Action Fund to support a Phase 3 study of VE303 and Phase 2 of VE202, with investors including Bill & Melinda Gates Foundation, Skyviews Life Science, and PureTech Health. Positive Phase 2 data for VE303 was published in JAMA, triggering a $23.8 million BARDA contract option toward a potential $81.9 million total. The company positioned itself as a leader in defined consortia therapeutics with advanced GMP manufacturing. |
| Jan 2021 | Undisclosed stage | Pfizer Breakthrough Growth Initiative (lead) | $25M | - | Vedanta Biosciences is a clinical-stage biotherapeutics company founded by PureTech Health and headquartered in Cambridge, Massachusetts. The company develops a new category of therapies for immune-mediated diseases based on rationally defined consortia of human microbiome-derived bacteria, with a focus on inflammatory bowel disease and recurrent clostridioides difficile infection. Vedanta received a $25 million investment from Pfizer as part of the Pfizer Breakthrough Growth Initiative, announced in January 2021, to support development of its lead candidates VE303 (for recurrent CDI) and VE202 (for mild to moderate ulcerative colitis). In July 2021, Vedanta completed a $68 million Series D financing round led by affiliates of Magnetar Capital, which included the Pfizer investment as a participant. The Series D also featured participation from Verition Fund Management, Fosun Health Capital, PureTech Health, Rock Springs Capital, Skyviews Life Science, JSR Corporation, SymBiosis LLC, Shumway Capital, and Health for Life Capital. Proceeds from the Series D were designated to advance the pipeline including progressing VE303 into Phase 3 clinical trials and initiating Phase 2 trials of VE202, with topline data from the VE303 Phase 2 trial anticipated in Q3 2021. Michael Vincent, Senior Vice President and Chief Scientific Officer of Pfizer's Inflammation & Immunology Research Unit, joined Vedanta's Scientific Advisory Board as part of the partnership. |
| Sep 2019 | Series C | Shinhan Private Equity; Bill & Melinda Gates Foundation; Bristol-Myers Squibb; SV Investment; Rockspring Capital; Fontus Capital; Partners Investment; QUAD Investment Management; Shinhan Capital | $17M | - | Vedanta Biosciences raised $16.6 million in a Series C-2 round on September 23, 2019, from investors including FC Capital Partners, Partners Investment, QUAD Investment Management, Shinhan Capital-Yeollim Partners, Shinhan Investment-Private Equity, SV Investment, and Symbiosis. This round brought the total capital raised in the Series C to $62.1 million. The company pioneers therapies modulating the human microbiome and host immune system interactions, rationally designing drug candidates from consortia of human commensal bacteria for autoimmune, inflammatory, and infectious diseases. Prior to this, Vedanta had completed earlier funding rounds, with total funding exceeding $112 million by the Series C. The company operates from Cambridge, Massachusetts, advancing a pipeline using its proprietary technology platform for discovery, development, and manufacturing of live commensal microbe-based drugs. |
| May 2019 | Series C | Shumway Capital; JSR; Partners Investment; Symbiosis Group | $19M | - | Vedanta Biosciences is a clinical-stage biotechnology company headquartered in Cambridge, Massachusetts, focused on developing microbiome-derived therapies using rationally defined consortia of human bacteria to treat immune-mediated diseases, including food allergies, cancers, drug-resistant infections, and recurrent Clostridioides difficile infection. Founded in 2010 and backed by PureTech Health, the company advances oral consortia therapeutics as a novel modality beyond fecal microbiota transplants. On May 13, 2019, Vedanta Biosciences announced an $18.5 million extension to its Series C financing, bringing the total round to $45.5 million. New investors JSR Corporation, Shumway Capital, SymBiosis LLC, and Partners Investment Co., Ltd. joined existing backers including the Bill & Melinda Gates Foundation, Bristol-Myers Squibb, Rock Springs Capital, Invesco Asset Management, Health for Life (Seventure Partners), and PureTech Health. Proceeds funded advancement of Vedanta's clinical pipeline, including a Phase 1/2 study of VE416 for food allergy, a Phase 1b/2 study combining VE800 with OPDIVO (nivolumab) for advanced or metastatic cancers, and the ongoing Phase 2 study of VE303 for recurrent C. difficile infection. CEO Bernat Olle highlighted the platform's potential for broad medical needs where current treatments are inadequate. Subsequent rounds included a $106.5 million financing in 2023 for Phase 3 of VE303 and Phase 2 of VE202 for ulcerative colitis, with investors like AXA IM Alts and AMR Action Fund. |
| Dec 2018 | Series C | Invesco Mutual Fund; Bill & Melinda Gates Foundation; Seventure Partners; Bristol-Myers Squibb; Rock Springs Capital; PureTech Health | $45M | - | Vedanta Biosciences, a clinical-stage company developing therapies for immune-mediated diseases based on rationally-defined consortia of human microbiome-derived bacteria, raised $27 million in a Series C financing announced December 24, 2018, with participation from the Bill & Melinda Gates Foundation, Bristol-Myers Squibb, Rock Springs Capital, Invesco Asset Management, Seventure Partners, and PureTech Health. Some sources describe it as a $45.4 million Series C round on December 24, 2018, potentially including prior tranches. The proceeds support advancement of its pipeline, including Phase 1/2 study of VE416 in food allergy, Phase 1b/2 study of VE800 combined with Bristol-Myers Squibb’s Opdivo in advanced cancers, and Phase 2 study of VE303 in recurrent Clostridium difficile infection. Vedanta also had a partnership with Janssen for VE202 in inflammatory bowel disease, triggering a $12 million milestone payment shortly before the round. The company differentiates its approach by using defined bacterial consortia with drug-like properties to induce robust immune responses, contrasting with fecal transplants. Founded in 2010 and co-founded by PureTech Health, Vedanta focuses on microbiome-immune system interactions for diseases like food allergy, cancer, C. difficile infection, and IBD. At the time, Vedanta was advancing multiple clinical programs and leveraging partnerships with major players like Janssen and BMS. The microbiome therapeutics market was growing, with competitors like Kaleido Biosciences and uBiome also raising significant Series C rounds in 2018. |
| Jun 2016 | Undisclosed stage | Rock Springs Capital (lead); Invesco; PureTech Health | $50M | - | Vedanta Biosciences is a clinical-stage microbiome company based in Cambridge, MA, founded in 2010, that develops orally delivered defined bacterial consortia therapies designed to treat inflammatory and infectious diseases. The company's platform is built on libraries of bacteria derived from the human microbiome. On June 6, 2016, Vedanta Biosciences closed a Series B financing round of $50 million led by Rock Springs Capital, with participation from new investors Invesco Asset Management and other backers. This round was part of the company's capital raising history that included earlier Series A funding and would later be followed by subsequent Series C, D, and E rounds. The company had accumulated over $112 million in total funding by its Series C round in 2019, which featured pharmaceutical firms Bristol-Myers Squibb and JSR Corporation as investors. By July 2021, the company completed a $68 million Series D round led by Magnetar Capital that included a significant $25 million investment from Pfizer, demonstrating strong support from major pharmaceutical companies for its microbiome therapy pipeline. |
Who has invested in Vedanta Biosciences?
26 investors have backed Vedanta Biosciences across its funding rounds, including Rock Springs Capital, PureTech Health, Partners Investment, Bristol-Myers Squibb, Bill & Melinda Gates Foundation and JSR.
Lead investors include AMR Action Fund, BNP Paribas Asset Management, AXA Investment Managers, Magnetar Capital, Pfizer Breakthrough Growth Initiative and 1 other investor.
Vedanta Biosciences Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Jun 2016 | ||
| 3 | Participant | Jun 2016 | ||
| 2 | Participant | May 2019 | ||
| 2 | Participant | Dec 2018 | ||
| 2 | Participant | Dec 2018 | ||
| 2 | Participant | May 2019 | ||
| 2 | Participant | May 2019 | ||
| 2 | Lead | Apr 2023 | ||
| -- | 1 | Lead | Jan 2021 | |
| 1 | Participant | Sep 2019 | ||
| 1 | Participant | Jul 2021 | ||
| 1 | Participant | Jul 2021 | ||
| 1 | Participant | Jun 2016 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
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Start Free TrialVedanta Biosciences Competitors
Vedanta Biosciences competitors include listed companies like Fulcrum Therapeutics and Amarin Corp, and private ones like City Therapeutics, GC Therapeutics, Inceptive and HebeCell.
| Company | HQ | Status | Revenue | EBITDA | Valuation |
|---|---|---|---|---|---|
| Private | - | - | $281M | ||
| Private | - | - | $280M | ||
| Private | - | - | $300M | ||
| Private | - | - | $268M | ||
| Publicly listed | - | ($73M) | $287M | ||
| Publicly listed | $214M | ($44M) | $286M |
Vedanta Biosciences Public Comps
Vedanta Biosciences is still privately-owned, but its public comps include Fulcrum Therapeutics, Amarin Corp, PegBio, Immuneering, Abclon, Antibiotice, Racura Oncology, Upstream Bio, Celon Pharma and Shanghai Hile Bio-Tech.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($73M) | - | - | - | - | |||
| $214M | ($44M) | - | - | - | - | |||
| - | ($31M) | - | - | (7.4x) | - | |||
| - | ($59M) | - | - | (2.5x) | - | |||
| $3M | ($12M) | 76.7x | - | (21.5x) | - | |||
| $141M | $26M | 2.5x | - | 13.9x | - | |||
| $2M | ($8M) | 127.7x | 127.7x | (31.7x) | (74.9x) | |||
| $3M | ($160M) | 11.3x | 11.7x | (0.2x) | (0.2x) | |||
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Common questions about Vedanta Biosciences
| When was Vedanta Biosciences founded? | Vedanta Biosciences was founded in 2010. |
| Where is Vedanta Biosciences headquartered? | Vedanta Biosciences is headquartered in United States. |
| Is Vedanta Biosciences publicly listed? | No, Vedanta Biosciences is a private, VC-backed company. |
| What is Vedanta Biosciences' valuation? | Vedanta Biosciences was last valued at $287M in its Series D in July 2021. |
| How much funding has Vedanta Biosciences raised? | Vedanta Biosciences has raised $370M across 8 funding rounds. |
| What was Vedanta Biosciences' last funding round? | Vedanta Biosciences' last funding round was a $40M undisclosed-stage round in August 2026, led by AMR Action Fund and BNP Paribas Asset Management. |
| Who are Vedanta Biosciences' investors? | Vedanta Biosciences' investors include Rock Springs Capital, PureTech Health, Shumway Capital, Bill & Melinda Gates Foundation, Bristol-Myers Squibb, JSR, Partners Investment, AMR Action Fund, Pfizer Breakthrough Growth Initiative, Shinhan Private Equity and 16 others. |
| Which companies are comparable to Vedanta Biosciences? | Companies comparable to Vedanta Biosciences include City Therapeutics, GC Therapeutics, Inceptive, HebeCell, Fulcrum Therapeutics and Amarin Corp. |
See companies similar to Vedanta Biosciences
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