Valo Health Valuation, Funding & Investors

Valo Health is valued at $300M as of March 2021.

Last Valo Health valuation

$300M

Series B · Mar 2021

Last Valo Health funding round

$110M

Series B · Mar 2021

Cumulative funding Valo Health raised

$400M

across 3 funding rounds

Key investors in Valo Health

Valo Health Overview

About Valo Health

Valo Health is a Boston-headquartered biotech firm that integrates multimodal human data into its Opal Computational Platform for drug discovery. The platform analyzes real-world evidence, clinical, and molecular datasets to advance therapies in cardiovascular, metabolic, renal, oncology, and neurodegenerative areas. Valo maintains offices in Lexington and New York City alongside its Boston base. Launched in 2018 by Flagship Pioneering, it collaborates with AstraZeneca on heart failure programs and Bayer on cardiovascular targets. The company processes petabytes of data to nominate drug candidates and optimize trials.


Founded

2019

HQ

United StatesBoston, MA

Status

Privately held

Customer focus

B2B

Revenue model

Licensing

Valuation

$300M (Mar 2021)

Valo Health Valuation

Valo Health is currently valued at $300M, based on its Series B in March 2021.

The $110M round was led by Koch Disruptive Technologies.

Valo Health valuation by funding round

Valo Health valuation by funding round
DateStageValuation
Mar 2021Series B$300M

Valo Health Funding History

Valo Health has raised a total of $400M across 3 funding rounds.

Valo Health's first fundraising round was a $100M Series A in July 2019. The most recent completed round was a $110M Series B in March 2021.

Valo Health funding rounds

Valo Health funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Mar 2021Series BKoch Disruptive Technologies (lead)$110M$300MValo Health, a technology company founded in 2019, develops the Opal Computational Platform, which integrates machine learning and human-centric patient data to accelerate drug discovery and development, aiming to reduce time, cost, and failure rates across diseases like cancer, neurodegenerative, and cardiovascular conditions. The platform combines vast datasets and computational models to identify therapeutic opportunities faster than traditional methods. On March 9, 2021, Valo Health announced the final closing of its Series B funding round at $300 million, including a $110 million investment from Koch Disruptive Technologies, following a $190 million first close in January led by PSP Investments and participation from Flagship Pioneering, Invus Public Equities, HBM Healthcare Investments, Atinum Investment, and Mirae Asset Capital. This brought total funding to over $450 million, including a prior $100 million raise in 2019. The funds were earmarked to scale the Opal platform and build a therapeutic pipeline. Valo launched after acquiring Forma Therapeutics' hit discovery capabilities and Numerate's modeling platform, enabling rapid progression from ideas to testable molecules. CEO David Berry, also a Flagship Pioneering partner, emphasized reimagining drug development in half the time and cost. Later developments included a planned SPAC merger with Khosla Ventures Acquisition Co. announced in 2021, valuing the combined entity at approximately $2.8 billion pro forma with $750 million cash, though execution details post-date the queried round.
Jan 2021Series BPSP Investments (lead); Flagship Pioneering; HBM Healthcare Investments; Invus; Longevity Vision Fund; Mirae Asset Capital; Atinum Investment; E Squared Capital Management$190M-Valo Health, a technology company transforming drug discovery and development through its Opal Computational Platform, closed a $190 million Series B financing on January 11, 2021, led by PSP Investments. Existing investors including Flagship Pioneering participated, alongside new ones such as Invus Public Equities, HBM Healthcare Investments, Atinum Investment, and Mirae Asset Capital, bringing total capital raised to over $285 million. Proceeds fund therapeutic programs in cancer, cardiovascular disease, and neurodegenerative disease, Opal platform build-out, working capital, and general purposes. Valo emphasized rapid progress in under two years, integrating computational platform with massive data and expert teams to accelerate and reduce costs of life-changing drugs.
Jul 2019Series AFlagship Pioneering (lead); PSP Investments; Longevity Vision Fund$100M-Valo Health was founded in 2019 by Flagship Pioneering as a drug discovery technology company designed to transform how oncology, neurodegenerative, and cardiovascular disease drugs are created, developed, and approved. The company emerged from stealth in September 2020 with approximately $100 million in initial funding from Flagship Pioneering. Valo's flagship product is the Opal Computational Platform, a first-of-its-kind, end-to-end drug development platform that integrates machine learning, cloud computing, and data to accelerate drug discovery and development. During its early years, Valo executed a strategic acquisition strategy to build out its capabilities. In September 2019, the company acquired Numerate, which brought engineers and a platform containing over 30,000 models and over 70 trillion molecules that powered more than 25 drug programs. In March 2020, Valo acquired assets from FORMA Therapeutics, including a skilled research and development team, compound and research libraries, a global intellectual property portfolio, and two early discovery labs. Valo continued raising capital through multiple funding rounds. In January 2021, the company announced a Series B round totaling $300 million, with Koch Disruptive Technologies (the investment arm of Koch Industries) contributing $110 million to the round. By June 2021, Valo entered merger discussions with Khosla Ventures Acquisition Co, a special purpose acquisition company, with the combined entity expected to be valued at $2.8 billion. However, this deal was terminated by the end of 2021 due to market conditions. As of recent reports, Valo has raised approximately $595 million in total venture funding and remains privately held. Valo Health has established itself as a leader in AI-driven drug discovery through strategic partnerships and collaborations. In 2024, the company signed an expanded partnership with Novo Nordisk involving $190 million upfront and up to $4.6 billion in milestone payments, demonstrating significant market validation for its computational drug discovery platform. The company's Logica platform, powered by the Opal Computational Platform, has been adopted by leading pharmaceutical organizations including Charles River Laboratories and major pharma companies for accelerating the identification and optimization of drug candidates.

Who has invested in Valo Health?

9 investors have backed Valo Health across its funding rounds, including Flagship Pioneering, PSP Investments, Longevity Vision Fund, Atinum Investment, Invus and HBM Healthcare Investments.

Lead investors include Koch Disruptive Technologies, PSP Investments and Flagship Pioneering.


Valo Health Investors

Investors in Valo Health by funding rounds participated
InvestorHQRoundsRoleFirst check
Flagship PioneeringUnited StatesUnited States2LeadJul 2019
PSP InvestmentsCanadaOttawa2LeadJul 2019
Longevity Vision FundUnited StatesNew York City, NY2ParticipantJul 2019
HBM Healthcare InvestmentsSwitzerlandZug1ParticipantJan 2021
InvusUnited StatesNew York City, NY1ParticipantJan 2021
Koch Disruptive TechnologiesUnited StatesWichita, KS1LeadMar 2021
Mirae Asset CapitalSouth KoreaSeoul1ParticipantJan 2021

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Acquisitions by Valo Health

Valo Health has acquired 3 companies to date.

Last acquisition by Valo Health was on April 5th 2022. Valo Health acquired TARA Biosystems for undisclosed valuation.


Latest Acquisitions by Valo Health

TARA Biosystems
Courier Therapeutics
Numerate
Description
TARA Biosystems is a New York City-based biotechnology company developing engineered human cardiac tissues for drug discovery and safety testing. Its Cardiac Tissue Platform uses stem cell-derived cardiomyocytes matured to adult-like functionality, measuring contractile force and other physiological parameters. The models support cardiovascular drug development for pharmaceutical clients evaluating efficacy and toxicity.
Courier Therapeutics is a biotechnology company developing protein-based therapeutics for cancer immunotherapy. Cambridge, Massachusetts-headquartered, it engineers masking proteins that activate only in tumor microenvironments, reducing systemic toxicity compared to CAR-T and checkpoint inhibitors. The platform targets solid tumors and extends to autoimmune diseases. Founded in 2020, Courier Therapeutics raised seed funding to advance preclinical candidates.
Numerate is a San Bruno-headquartered computational drug discovery firm using cloud-based machine learning to screen 10 billion compounds for metabolic diseases. Founded in 2008, its Prediction Platform forecasts ADME properties and efficacy in models for type 2 diabetes and NASH, partnering with Roche to nominate preclinical candidates.
HQ CountryUnited StatesUnited StatesUnited States
HQ City
New York City, NY
Houston, TX
San Francisco, CA
Deal Date5 Apr 202227 Jul 20211 Nov 2019
Valuationundisclosed$510Mundisclosed
EV/Revenue
EV/EBITDA

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Valo Health Competitors

Valo Health competitors include listed companies like Abclon and Zentalis Pharma, and private ones like Hexagon Bio, Geneplus-Beijing Co. Ltd., CureGenetics and Vanqua Bio.

Public and private companies comparable to Valo Health
CompanyHQStatusRevenueEBITDAValuation
Hexagon BioUnited StatesSan Francisco, CAPrivate--$297M
Geneplus-Beijing Co. Ltd.ChinaGuangzhouPrivate--$295M
CureGeneticsChinaSuzhouPrivate--$311M
Vanqua BioUnited StatesChicago, ILPrivate--$333M
AbclonSouth KoreaSouth KoreaPublicly listed$3M($12M)$293M
Zentalis PharmaUnited StatesUnited StatesPublicly listed-($136M)$302M

Valo Health Public Comps

Valo Health is still privately-owned, but its public comps include Zentalis Pharma, Fate Therapeutics, InflaRx, Celon Pharma, Palisade Bio, Shanghai Hile Bio-Tech, AprilBio, Cuorips, Clinuvel Pharmaceuticals and Abclon.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Zentalis Pharma-($136M)--(1.2x)(0.9x)
Fate Therapeutics$7M($134M)33.9x38.1x(1.7x)(1.8x)
InflaRx$34K($54M)3656.9x77904.5x(2.3x)(2.7x)
Celon Pharma$48M$4M6.7x4.7x79.9x40.5x
Palisade Bio-($17M)-556.5x(10.2x)-
Shanghai Hile Bio-Tech$28M($26M)9.6x-(10.5x)-
AprilBio$2M($9M)157.0x40.4x(29.0x)(155.8x)
Cuorips$1M($6M)209.2x214.0x(46.5x)-

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Common questions about Valo Health

When was Valo Health founded?Valo Health was founded in 2019.
Where is Valo Health headquartered?Valo Health is headquartered in Boston, MA, United States.
Is Valo Health publicly listed?No, Valo Health is a private, VC-backed company.
What is Valo Health's valuation?Valo Health was last valued at $300M in its Series B in March 2021.
How much funding has Valo Health raised?Valo Health has raised $400M across 3 funding rounds.
What was Valo Health's last funding round?Valo Health's last funding round was a $110M Series B in March 2021, led by Koch Disruptive Technologies.
Who are Valo Health's investors?Valo Health's investors include Flagship Pioneering, PSP Investments, Longevity Vision Fund, HBM Healthcare Investments, Invus, Koch Disruptive Technologies, Mirae Asset Capital, Atinum Investment and E Squared Capital Management.
Which companies are comparable to Valo Health?Companies comparable to Valo Health include Hexagon Bio, Geneplus-Beijing Co. Ltd., CureGenetics, Vanqua Bio, Abclon and Zentalis Pharma.
How many companies has Valo Health acquired?Valo Health has acquired 3 companies, including TARA Biosystems, Courier Therapeutics and Numerate.
What was the largest acquisition by Valo Health?The $510M acquisition of Courier Therapeutics in July 2021 is the largest acquisition Valo Health has made to date.

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