Transcend Therapeutics Acquisition, Valuation, Funding & Investors

Transcend Therapeutics was acquired by Otsuka Holdings for $700M in March 2026.

Transcend Therapeutics acquisition price

$700M

Acquired by Otsuka Holdings · Mar 2026

Cumulative funding Transcend Therapeutics raised

$40M

across 1 funding round

Key investors in Transcend Therapeutics

  • Global Founders Capital
  • Alpha Wave Global
  • Emerald Development Managers
  • Delphi VC
  • Integrated

Transcend Therapeutics Overview

About Transcend Therapeutics

Transcend Therapeutics is a biopharmaceutical developer targeting diseases from oxidative stress and tissue damage, established in 1992 in Waltham, Massachusetts. The company advances small molecule therapeutics to mitigate reactive oxygen species in conditions like cardiovascular disease and neurodegeneration. Its pipeline includes antioxidants delivered via proprietary formulations for improved bioavailability. Transcend collaborates with academic institutions on preclinical studies and holds patents for enzyme modulators. Operations focus on Phase I/II trials for neurology indications with funding from venture partners.


Founded

1992

HQ

United StatesBoston, MA

Status

Acquired

Customer focus

B2B

Revenue model

Licensing

Valuation

$700M (acquired Mar 2026)

Transcend Therapeutics Acquisition

Transcend Therapeutics was acquired by Otsuka Holdings for $700M on 26 March 2026.

Before the acquisition Transcend Therapeutics had raised $40M across 1 funding round.

Transcend Therapeutics acquisition details
AcquirerDateTypePrice
26 Mar 2026Strategic M&A$700M

Transcend Therapeutics Funding History

Transcend Therapeutics has raised a total of $40M across 1 funding round.

Transcend Therapeutics funding rounds

Transcend Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
Feb 2023Series AAlpha Wave Global (lead); Integrated (lead); Delphi VC; Global Founders Capital; Emerald Development Managers$40MTranscend Therapeutics is a biotechnology company developing next-generation psychoactive medicines for neuropsychiatric diseases, including post-traumatic stress disorder (PTSD). Its lead compound, TSND-201 (methylone, an MDMA analogue), has real-world data showing robust responses in PTSD patients and is planned for multiple clinical trials, including a phase II study. The company operates as a Public Benefit Corporation, pledging 10% of founding shares to nonprofits focused on scientific research and patient access. On February 23, 2023, Transcend closed a $40 million Series A funding round led by Alpha Wave Global and Integrated Investment Partners, with participation from Global Founders Capital, Emerald Development Managers, and others. This brought total funding to nearly $42 million. The proceeds will fund clinical trials and pipeline development for methylone-based therapies as rapid-acting, non-hallucinogenic treatments. The leadership team has experience across drug development, contributing to 13 FDA-approved drugs worth $7 billion in M&A and public value. Investors highlighted the team's expertise and the lead compound's potential to address the mental health crisis. Note that a separate company named Transcend (transcend.io), focused on data privacy compliance, raised $40M in a Series B in 2024 from different investors like StepStone Group, unrelated to this biotech firm.

Who has invested in Transcend Therapeutics?

5 investors have backed Transcend Therapeutics across its funding rounds, including Global Founders Capital, Alpha Wave Global, Emerald Development Managers, Delphi VC and Integrated.

Lead investors include Alpha Wave Global and Integrated.


Transcend Therapeutics Investors

Investors in Transcend Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
IntegratedUnited StatesNew York City, NY1LeadFeb 2023
Delphi VCUnited StatesNew York City, NY1ParticipantFeb 2023
Global Founders CapitalGermanyBerlin1ParticipantFeb 2023

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Transcend Therapeutics Competitors

Transcend Therapeutics competitors include listed companies like Ironwood Pharmaceuticals, Nuvectis Pharma, Zevra Therapeutics and CHO Pharma, and private ones like AdvanCell and Angiocrine Bioscience.

Public and private companies comparable to Transcend Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
AdvanCellAustraliaSydneyPrivate--$700M-
Ironwood PharmaceuticalsUnited StatesUnited StatesPublicly listed$296M$101M$699M2.4x
Nuvectis PharmaUnited StatesUnited StatesPublicly listed-($28M)$698M-
Zevra TherapeuticsUnited StatesUnited StatesPublicly listed$106M$92M$703M3.5x
Angiocrine BioscienceUnited StatesNew York City, NYPrivate--$697M-
CHO PharmaTaiwanTaiwanPublicly listed$45K($9M)$705M-

Transcend Therapeutics Public Comps

Transcend Therapeutics is no longer listed, but its public comps include Ironwood Pharmaceuticals, Nuvectis Pharma, Zevra Therapeutics, CHO Pharma, Sagimet Biosciences, SK Chemicals, Genfit, XOMA Royalty, Tempo Scan Pacific and Monopar Therapeutics.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Ironwood Pharmaceuticals$296M$101M3.4x2.4x10.1x3.6x
Nuvectis Pharma-($28M)--(24.5x)(23.3x)
Zevra Therapeutics$106M$92M4.5x3.5x5.3x9.5x
CHO Pharma$45K($9M)14338.3x-(68.6x)-
Sagimet Biosciences-($57M)--(8.0x)-
SK Chemicals$1.7B$168M1.0x0.9x10.5x10.0x
Genfit$75M($98M)9.9x7.9x(7.7x)52.1x
XOMA Royalty$52M$11M14.4x14.4x65.7x65.7x

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Common questions about Transcend Therapeutics

When was Transcend Therapeutics founded?Transcend Therapeutics was founded in 1992.
Where is Transcend Therapeutics headquartered?Transcend Therapeutics is headquartered in Boston, MA, United States.
Is Transcend Therapeutics publicly listed?No, Transcend Therapeutics was acquired by Otsuka Holdings in March 2026.
Who acquired Transcend Therapeutics?Transcend Therapeutics was acquired by Otsuka Holdings in March 2026.
How much was Transcend Therapeutics acquired for?Transcend Therapeutics was acquired for $700M in March 2026.
How much funding has Transcend Therapeutics raised?Transcend Therapeutics has raised $40M across 1 funding round.
What was Transcend Therapeutics' last funding round?Transcend Therapeutics' last funding round was a $40M Series A in February 2023, led by Alpha Wave Global and Integrated.
Who are Transcend Therapeutics' investors?Transcend Therapeutics' investors include Integrated, Delphi VC, Global Founders Capital, Alpha Wave Global and Emerald Development Managers.
Which companies are comparable to Transcend Therapeutics?Companies comparable to Transcend Therapeutics include AdvanCell, Ironwood Pharmaceuticals, Nuvectis Pharma, Zevra Therapeutics, Angiocrine Bioscience and CHO Pharma.

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