AdvanCell Valuation, Funding & Investors

AdvanCell is valued at $700M as of February 2025.

Last AdvanCell valuation

$700M

Series C · Feb 2025

Last AdvanCell funding round

$315M

Series D · Jul 2026

Cumulative funding AdvanCell raised

$439M

across 3 funding rounds

Key investors in AdvanCell

  • Morningside
  • SV Health Investors
  • Abingworth
  • Brandon Capital
  • SymBiosis
  • Fidelity

AdvanCell Overview

About AdvanCell

AdvanCell is a Melbourne-based clinical-stage radiopharmaceutical company developing targeted alpha therapies for cancer. Its lead candidate, AdVance-32, uses lead-212 isotopes conjugated to actinium-225 chelators to deliver cytotoxic radiation to prostate, ovarian, and neuroendocrine tumors. Phase 1 trials at Peter MacCallum Cancer Centre demonstrate tumor uptake with minimal off-target effects. AdvanCell manufactures isotopes at its lead-212 generator facility in Belgium.


Founded

2019

HQ

AustraliaSydney

Status

Privately held

Customer focus

B2C

Revenue model

Product sales

Valuation

$700M (Feb 2025)

AdvanCell Valuation

AdvanCell is currently valued at $700M, based on its Series C in February 2025.

The $112M round was led by Abingworth, Sanofi Ventures, SV Health Investors and SymBiosis, with participation from Tenmile, Brandon Capital and Morningside.

AdvanCell valuation by funding round

AdvanCell valuation by funding round
DateStageValuation
Feb 2025Series C$700M

AdvanCell Funding History

AdvanCell has raised a total of $439M across 3 funding rounds.

AdvanCell's first fundraising round was a $12M Series B in August 2022. The most recent completed round was a $315M Series D in July 2026.

AdvanCell funding rounds

AdvanCell funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Jul 2026Series DAlly Bridge Group (lead); Alpha Wave Global (lead); Eventide; Velosity Capital; SV Health Investors; Fidelity; SymBiosis; Piper Sandler; T. Rowe Price; Abingworth; Eli Lilly; Bain Capital Life Sciences; Brandon Capital$315M-AdvanCell Pty, a clinical-stage radiopharmaceutical company backed by Eli Lilly & Co., raised $315 million in a new funding round announced on July 15, 2026. The financing underscores strong investor confidence in AdvanCell's experimental targeted alpha therapy platform for cancer treatment, with Eli Lilly's continued support serving as a key strategic anchor. AdvanCell specializes in developing innovative cancer therapies using its proprietary Lead-212 (Pb-212) production technology and radionuclide development infrastructure, operating as a vertically integrated company with manufacturing and clinical development capabilities. The company previously secured a $112 million Series C round co-led by SV Health Investors, Sanofi Ventures, Abingworth, and SymBiosis, and entered an expanded strategic collaboration with Eli Lilly in February 2025 to accelerate the clinical advancement of an expanded portfolio of targeted alpha therapies. Eli Lilly's connection to AdvanCell originated from its $1.4 billion acquisition of Point Biopharma in 2023, which included AdvanCell as part of Point's pipeline. AdvanCell is scaling its U.S. operations, recently appointing Justyna Kelly (formerly of Eli Lilly's Indianapolis radioligand therapy site) as CTO and François Gaudet as CSO to strengthen executive leadership. Financial metrics including revenue and EBITDA were not disclosed in the available reports.
Feb 2025Series CAbingworth (lead); Sanofi Ventures (lead); SV Health Investors (lead); SymBiosis (lead); Tenmile; Brandon Capital; Morningside$112M$700MAdvanCell is a Sydney-based clinical-stage radiopharmaceutical company founded in 2019, focused on developing targeted alpha therapies (TATs) for cancer treatment, particularly its lead Pb-212-based candidate ADVC001 for metastatic prostate cancer. The company is advancing a phase 1/2 dose-escalation trial (TheraPb) and has built a 40,000-square-foot manufacturing facility with world-class pre-clinical infrastructure and a growing pipeline of radionuclide therapies. On February 3, 2025, AdvanCell closed an oversubscribed $112 million Series C financing round co-led by SV Health Investors, Sanofi Ventures, Abingworth, and SymBiosis, with participation from Morningside (prior Series B lead), Tenmile, Brandon Capital, and others. This follows a $18 million Series B in 2022 led by Morningside. The funding will support manufacturing scale-up, clinical development acceleration, and progression toward commercialization of its therapies. One source reports the Series C at a $700 million valuation, highlighting strong investor confidence in AdvanCell's first-in-class Pb-212-PSMA program and manufacturing platform amid a competitive radiopharma landscape. The company now employs 60 team members and positions itself as a global leader in radionuclide-based cancer therapeutics, with ongoing patient enrollment in its prostate cancer trial. AdvanCell operates in a burgeoning Australian radiopharma sector, competing with players like Telix Pharmaceuticals, which has pursued acquisitions and an aborted IPO.
Aug 2022Series BMorningside (lead)$12M-AdvanCell is an Australian radiopharmaceutical company founded in 2019, developing targeted alpha therapies (TATs) using lead-212 (Pb-212) isotopes, with its lead candidate ADVC001 in phase 1/2 trials for metastatic prostate cancer. The company focuses on scalable isotope supply to enable multiple cancer treatments, featuring a 40,000-square-foot manufacturing facility and pre-clinical infrastructure. AdvanCell closed an A$18M (approximately US$18M or $12.3M USD equivalent based on query) Series B funding round on August 23, 2022, led by Morningside. This followed earlier funding and preceded a US$112M oversubscribed Series C in February 2025 co-led by SV Health Investors, Sanofi Ventures, Abingworth, and SymBiosis, with Morningside participation and new investors like Tenmile and Brandon Capital. The Series B funded acceleration of growth and advancement of the 212Pb-PSMA clinical program, while Series C supports manufacturing scale-up and therapy commercialization.

Who has invested in AdvanCell?

16 investors have backed AdvanCell across its funding rounds, including Morningside, SV Health Investors, Abingworth, Brandon Capital, SymBiosis and Fidelity.

Lead investors include Ally Bridge Group, Alpha Wave Global, Abingworth, Sanofi Ventures, SV Health Investors and 2 other investors.


AdvanCell Investors

Investors in AdvanCell by funding rounds participated
InvestorHQRoundsRoleFirst check
SV Health InvestorsUnited StatesBoston, MA2LeadFeb 2025
SymBiosisUnited StatesBentonville, AR2LeadFeb 2025
AbingworthUnited KingdomLondon2LeadFeb 2025
Brandon CapitalAustraliaMelbourne2ParticipantFeb 2025
MorningsideUnited StatesBoston, MA2LeadAug 2022
EventideUnited StatesBoston, MA1ParticipantJul 2026
Velosity CapitalUnited StatesJackson, MS1ParticipantJul 2026
FidelityUnited StatesBoston, MA1ParticipantJul 2026
Piper SandlerUnited StatesMinneapolis, MN1ParticipantJul 2026
TenmileAustraliaPerth1ParticipantFeb 2025
T. Rowe PriceUnited StatesBaltimore, MD1ParticipantJul 2026
Eli LillyUnited StatesIndianapolis, IN1ParticipantJul 2026
Bain Capital Life SciencesUnited StatesBoston, MA1ParticipantJul 2026

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AdvanCell Competitors

AdvanCell competitors include listed companies like Ironwood Pharmaceuticals, Nuvectis Pharma, Zevra Therapeutics and CHO Pharma, and private ones like Angiocrine Bioscience and NGM Biopharmaceuticals.

Public and private companies comparable to AdvanCell
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Ironwood PharmaceuticalsUnited StatesUnited StatesPublicly listed$296M$101M$699M2.4x
Nuvectis PharmaUnited StatesUnited StatesPublicly listed-($28M)$698M-
Zevra TherapeuticsUnited StatesUnited StatesPublicly listed$106M$92M$703M3.5x
Angiocrine BioscienceUnited StatesNew York City, NYPrivate--$697M-
CHO PharmaTaiwanTaiwanPublicly listed$45K($9M)$705M-
NGM BiopharmaceuticalsUnited StatesSan Francisco, CAPrivate$4M-$707M176.8x

AdvanCell Public Comps

AdvanCell is still privately-owned, but its public comps include Ironwood Pharmaceuticals, Nuvectis Pharma, Zevra Therapeutics, CHO Pharma, Sagimet Biosciences, SK Chemicals, Genfit, XOMA Royalty, Tempo Scan Pacific and Monopar Therapeutics.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Ironwood Pharmaceuticals$296M$101M3.4x2.4x10.1x3.6x
Nuvectis Pharma-($28M)--(24.5x)(23.3x)
Zevra Therapeutics$106M$92M4.5x3.5x5.3x9.5x
CHO Pharma$45K($9M)14338.3x-(68.6x)-
Sagimet Biosciences-($57M)--(8.0x)-
SK Chemicals$1.7B$168M1.0x0.9x10.5x10.0x
Genfit$75M($98M)9.9x7.9x(7.7x)52.1x
XOMA Royalty$52M$11M14.4x14.4x65.7x65.7x

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Common questions about AdvanCell

When was AdvanCell founded?AdvanCell was founded in 2019.
Where is AdvanCell headquartered?AdvanCell is headquartered in Sydney, Australia.
Is AdvanCell publicly listed?No, AdvanCell is a private, VC-backed company.
What is AdvanCell's valuation?AdvanCell was last valued at $700M in its Series C in February 2025.
How much funding has AdvanCell raised?AdvanCell has raised $439M across 3 funding rounds.
What was AdvanCell's last funding round?AdvanCell's last funding round was a $315M Series D in July 2026, led by Ally Bridge Group and Alpha Wave Global.
Who are AdvanCell's investors?AdvanCell's investors include SV Health Investors, SymBiosis, Abingworth, Brandon Capital, Morningside, Eventide, Velosity Capital, Fidelity, Piper Sandler, Tenmile and 6 others.
Which companies are comparable to AdvanCell?Companies comparable to AdvanCell include Ironwood Pharmaceuticals, Nuvectis Pharma, Zevra Therapeutics, Angiocrine Bioscience, CHO Pharma and NGM Biopharmaceuticals.

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