Tourmaline Bio Acquisition, Valuation, Funding & Investors

Tourmaline Bio was acquired by Novartis for $1.4B in September 2025.

Tourmaline Bio acquisition price

$1.4B

Acquired by Novartis · Sep 2025

Cumulative funding Tourmaline Bio raised

$112M

across 1 funding round

Key investors in Tourmaline Bio

  • Cowen Healthcare Investments
  • Deep Track Capital
  • TCG Crossover

Tourmaline Bio Overview

About Tourmaline Bio

Tourmaline Bio is a clinical-stage biopharmaceutical company developing antibody therapeutics for inflammatory diseases. Its lead candidate targets Th2-mediated conditions like atopic dermatitis, with phase 2 trials underway. Headquartered in New York, it advances programs against immune disorders using proprietary protein engineering platforms.


Founded

2021

HQ

United StatesNew York City, NY

Status

Acquired

Customer focus

B2B

Revenue model

Licensing

Valuation

$1.4B (acquired Sep 2025)

Tourmaline Bio Acquisition

Tourmaline Bio was acquired by Novartis for $1.4B on 9 September 2025.

Before the acquisition Tourmaline Bio had raised $112M across 1 funding round.

Tourmaline Bio, a New York-based clinical-stage biopharmaceutical company (NASDAQ: TRML), develops pacibekitug, an anti-IL-6 monoclonal antibody targeting systemic inflammation in atherosclerotic cardiovascular disease (ASCVD), with Phase 2 data showing significant reductions in C-reactive protein levels, a key cardiovascular risk biomarker. The company licensed pacibekitug from Pfizer and advanced it toward Phase 3 readiness, also exploring applications in thyroid eye disease; it originated from a 2023 reverse merger with Talaris Therapeutics. Novartis, a Swiss multinational pharmaceutical giant, agreed on September 8, 2025, to acquire Tourmaline for $48 per share in cash, equating to $1.4 billion on a fully diluted basis—a 59% premium over the prior closing price—and commenced a tender offer on September 29, 2025, securing 92.94% of shares (24 million shares) for $1.2 billion. The acquisition complements Novartis's cardiovascular pipeline by adding pacibekitug's differentiated IL-6 inhibition mechanism to address residual inflammatory risk in ASCVD, where no widely adopted anti-inflammatory therapies exist, aligning with Novartis's strategy to lead in cardiovascular innovation as stated by President of Development Shreeram Aradhye. Structured as a tender offer followed by a merger under Delaware Section 251(h), the deal closed on October 28, 2025, after regulatory approvals and majority tender, delisting Tourmaline from Nasdaq and making it an indirect wholly owned Novartis subsidiary; customary closing conditions were met ahead of the initial Q4 2025 target, with both companies operating independently until completion amid favorable Phase 2 results from May 2025 that analysts deemed promising despite initial stock reaction.

Tourmaline Bio acquisition details
AcquirerDateTypePrice
9 Sep 2025Strategic M&A$1.4B

Tourmaline Bio Funding History

Tourmaline Bio has raised a total of $112M across 1 funding round.

Tourmaline Bio funding rounds

Tourmaline Bio funding rounds
DateStageInvestorsRaisedDeal Summary
Jan 2023Series ACowen Healthcare Investments (lead); Deep Track Capital (lead); TCG Crossover (lead)$112MTourmaline Bio, founded in September 2021, is a clinical-stage biotechnology company focused on developing TOUR006, an anti-IL-6 antibody candidate for thyroid eye disease (TED) and atherosclerotic cardiovascular disease (ASCVD). The company completed a $112 million Series A financing in 2023 co-led by Deep Track Capital, Cowen Healthcare Investments, and TCGX, with participation from additional investors including Acuta Capital Partners, Affinity Asset Advisors, and others. Initial financing in May 2022 was provided by Hydra, KVP Capital, Petrichor, and QVT Family Office. In June 2023, Tourmaline announced a merger agreement with Talaris Therapeutics, a Nasdaq-listed late-stage clinical biotechnology company, which was expected to create a combined entity with approximately $210 million in cash at close, including a concurrent $75 million private placement from institutional life sciences investors. The merger represented a significant value-creation opportunity for Tourmaline's shareholders through exposure to TOUR006's near-term clinical milestones in both TED and ASCVD indications.

Who has invested in Tourmaline Bio?

3 investors have backed Tourmaline Bio across its funding rounds, including Cowen Healthcare Investments, Deep Track Capital and TCG Crossover.

Lead investors include Cowen Healthcare Investments, Deep Track Capital and TCG Crossover.


Tourmaline Bio Investors

Investors in Tourmaline Bio by funding rounds participated
InvestorHQRoundsRoleFirst check
TCG CrossoverUnited StatesSan Francisco, CA1LeadJan 2023

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Acquisitions by Tourmaline Bio

Tourmaline Bio has acquired 1 company to date.

Last acquisition by Tourmaline Bio was on June 22nd 2023. Tourmaline Bio acquired Talaris Therapeutics for undisclosed valuation.


Latest Acquisitions by Tourmaline Bio

Talaris Therapeutics
Description
Talaris Therapeutics is a Boston-headquartered clinical-stage biotech developing allogeneic cell therapies for organ transplant tolerance. Its lead candidate STAR-101 induces immune tolerance in kidney recipients, allowing discontinuation of immunosuppression after one year post-transplant from HLA-mismatched donors. The company advances trials in liver transplantation.
HQ CountryUnited States
HQ City
Louisville, KY
Deal Date22 Jun 2023
Valuationundisclosed
EV/Revenue
EV/EBITDA

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Tourmaline Bio Competitors

Tourmaline Bio competitors include listed companies like First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health and Pacific Shuanglin, and private ones like Moonlight Therapeutics and Grupo Cimed.

Public and private companies comparable to Tourmaline Bio
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Moonlight TherapeuticsUnited StatesAtlanta, GAPrivate--$1.4B-
First Tracks BiotherapeuticsUnited StatesUnited StatesPublicly listed-($179M)$1.4B-
ArriVent BioPharmaUnited StatesUnited StatesPublicly listed-($178M)$1.4B-
Phibro Animal HealthUnited StatesUnited StatesPublicly listed$1.5B$231M$1.4B1.4x
Pacific ShuanglinChinaChinaPublicly listed$393M$90M$1.4B-
Grupo CimedBrazilSão PauloPrivate--$1.4B-
Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
First Tracks Biotherapeutics-($179M)--(6.9x)(7.6x)
ArriVent BioPharma-($178M)--(5.8x)(5.2x)
Phibro Animal Health$1.5B$231M1.4x1.4x9.1x8.2x
Pacific Shuanglin$393M$90M3.6x-15.8x-
Damora Therapeutics-($211M)--(4.7x)(6.1x)
SOTHEMA$340M$75M4.3x4.2x19.6x-
Zhejiang Jolly$453M$126M3.1x2.7x11.2x10.4x
Cullinan Therapeutics-($242M)-115.6x(4.3x)(5.0x)

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Common questions about Tourmaline Bio

When was Tourmaline Bio founded?Tourmaline Bio was founded in 2021.
Where is Tourmaline Bio headquartered?Tourmaline Bio is headquartered in New York City, NY, United States.
Is Tourmaline Bio publicly listed?No, Tourmaline Bio was acquired by Novartis in September 2025.
Who acquired Tourmaline Bio?Tourmaline Bio was acquired by Novartis in September 2025.
How much was Tourmaline Bio acquired for?Tourmaline Bio was acquired for $1.4B in September 2025.
How much funding has Tourmaline Bio raised?Tourmaline Bio has raised $112M across 1 funding round.
What was Tourmaline Bio's last funding round?Tourmaline Bio's last funding round was a $112M Series A in January 2023, led by Cowen Healthcare Investments, Deep Track Capital and TCG Crossover.
Who are Tourmaline Bio's investors?Tourmaline Bio's investors include TCG Crossover, Cowen Healthcare Investments and Deep Track Capital.
Which companies are comparable to Tourmaline Bio?Companies comparable to Tourmaline Bio include Moonlight Therapeutics, First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health, Pacific Shuanglin and Grupo Cimed.
How many companies has Tourmaline Bio acquired?Tourmaline Bio has acquired 1 company, including Talaris Therapeutics.

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