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- Perfuse Therapeutics
Perfuse Therapeutics Acquisition, Valuation, Funding & Investors
Perfuse Therapeutics was acquired by Bayer Perú for $2.5B in May 2026.
Perfuse Therapeutics acquisition price
$2.5B
Acquired by Bayer Perú · May 2026
Cumulative funding Perfuse Therapeutics raised
$9M
across 1 funding round
Key investors in Perfuse Therapeutics
OrbiMed
Access Biotechnology
About Perfuse Therapeutics
Perfuse Therapeutics is a biotechnology company developing retinal perfusion therapies for glaucoma and other eye diseases. Headquartered in Boston, the firm advances small-molecule drugs to enhance blood flow in the optic nerve. Perfuse Therapeutics raised Series A funding in 2022 and conducts preclinical studies targeting dry AMD and diabetic retinopathy.
Founded
2018
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Licensing
Valuation
$2.5B (acquired May 2026)
Sectors
Perfuse Therapeutics Acquisition
Perfuse Therapeutics was acquired by Bayer Perú for $2.5B on 5 May 2026.
Before the acquisition Perfuse Therapeutics had raised $9M across 1 funding round.
Bayer agreed to acquire Perfuse Therapeutics for up to $2.45 billion, comprising $300 million upfront and up to $2.15 billion in development, regulatory, and commercial milestones. The deal is subject to Perfuse shareholder approval and antitrust clearances. The acquisition advances Bayer's ophthalmology pipeline with Perfuse's PER-001, a Phase II asset for glaucoma and diabetic retinopathy, and two additional clinical programs for eye disorders. It marks Bayer's first pharmaceutical acquisition since 2021 and its largest drug deal in years, timed amid patent expiry and biosimilar competition for its Eylea franchise, which generated combined sales of $8.04 billion last year. Perfuse Therapeutics, headquartered in San Francisco with R&D facilities in Durham, NC, specializes in drugs for eye diseases, focusing on its sole pipeline drug and clinical programs targeting glaucoma and diabetic retinopathy.
| Acquirer | Date | Type | Price |
|---|---|---|---|
| 5 May 2026 | Strategic M&A | $2.5B |
Perfuse Therapeutics Funding History
Perfuse Therapeutics has raised a total of $9M across 1 funding round.
Perfuse Therapeutics funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Jul 2020 | Series A | Access Biotechnology (lead); OrbiMed | $9M | Perfuse Therapeutics raised $9 million in a Series A funding round on July 29, 2020, led by Access Biotechnology with participation from OrbiMed and others including Camden Partners, Hatteras Venture, Lilly Asia Ventures, and We Capital. The company develops therapies to improve blood flow to the retina, targeting conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration with its lead candidate PER-001, a long-acting endothelin antagonist intravitreal implant. |
Who has invested in Perfuse Therapeutics?
2 investors have backed Perfuse Therapeutics across its funding rounds, including OrbiMed and Access Biotechnology.
Lead investors include Access Biotechnology.
Perfuse Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialPerfuse Therapeutics Competitors
Perfuse Therapeutics competitors include listed companies like China Res Double-Crane, Vera Therapeutics, Mineralys Therapeutics and Granules India, and private ones like Cambrian Biopharma and Sail Biomedicines.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $1.6B | $404M | $2.4B | 1.4x | ||
| Publicly listed | - | ($316M) | $2.5B | 115.4x | ||
| Private | - | - | $2.5B | - | ||
| Publicly listed | - | ($171M) | $2.5B | - | ||
| Publicly listed | $557M | $119M | $2.5B | 4.2x | ||
| Private | - | - | $2.6B | - |
Perfuse Therapeutics Public Comps
Perfuse Therapeutics is no longer listed, but its public comps include China Res Double-Crane, Vera Therapeutics, Mineralys Therapeutics, Granules India, Viridian Therapeutics, ACROBiosystems, Harmony Biosciences, Bavarian Nordic, Joincare Pharmaceutical and Supernus Pharmaceuticals.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $1.6B | $404M | 1.4x | 1.4x | 5.8x | 6.0x | |||
| - | ($316M) | - | 115.4x | (6.5x) | (4.8x) | |||
| - | ($171M) | - | - | (10.6x) | (5.7x) | |||
| $557M | $119M | 4.6x | 4.2x | 21.2x | 18.4x | |||
| $71M | ($365M) | 26.0x | 51.6x | (5.1x) | (4.5x) | |||
| $125M | $28M | 18.7x | 15.6x | 82.4x | 59.1x | |||
| $868M | $233M | 2.3x | 2.0x | 8.5x | 6.7x | |||
| $961M | $383M | 2.1x | 2.2x | 5.2x | 6.7x | |||
This data is available for Pro users. Sign up to see all Perfuse Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Perfuse Therapeutics
| When was Perfuse Therapeutics founded? | Perfuse Therapeutics was founded in 2018. |
| Where is Perfuse Therapeutics headquartered? | Perfuse Therapeutics is headquartered in San Francisco, CA, United States. |
| Is Perfuse Therapeutics publicly listed? | No, Perfuse Therapeutics was acquired by Bayer Perú in May 2026. |
| Who acquired Perfuse Therapeutics? | Perfuse Therapeutics was acquired by Bayer Perú in May 2026. |
| How much was Perfuse Therapeutics acquired for? | Perfuse Therapeutics was acquired for $2.5B in May 2026. |
| How much funding has Perfuse Therapeutics raised? | Perfuse Therapeutics has raised $9M across 1 funding round. |
| What was Perfuse Therapeutics' last funding round? | Perfuse Therapeutics' last funding round was a $9M Series A in July 2020, led by Access Biotechnology. |
| Who are Perfuse Therapeutics' investors? | Perfuse Therapeutics' investors include OrbiMed and Access Biotechnology. |
| Which companies are comparable to Perfuse Therapeutics? | Companies comparable to Perfuse Therapeutics include China Res Double-Crane, Vera Therapeutics, Cambrian Biopharma, Mineralys Therapeutics, Granules India and Sail Biomedicines. |
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