Perfuse Therapeutics Acquisition, Valuation, Funding & Investors

Perfuse Therapeutics was acquired by Bayer Perú for $2.5B in May 2026.

Perfuse Therapeutics acquisition price

$2.5B

Acquired by Bayer Perú · May 2026

Cumulative funding Perfuse Therapeutics raised

$9M

across 1 funding round

Key investors in Perfuse Therapeutics

  • OrbiMed
  • Access Biotechnology

Perfuse Therapeutics Overview

About Perfuse Therapeutics

Perfuse Therapeutics is a biotechnology company developing retinal perfusion therapies for glaucoma and other eye diseases. Headquartered in Boston, the firm advances small-molecule drugs to enhance blood flow in the optic nerve. Perfuse Therapeutics raised Series A funding in 2022 and conducts preclinical studies targeting dry AMD and diabetic retinopathy.


Founded

2018

HQ

United StatesSan Francisco, CA

Status

Acquired

Customer focus

B2B

Revenue model

Licensing

Valuation

$2.5B (acquired May 2026)

Perfuse Therapeutics Acquisition

Perfuse Therapeutics was acquired by Bayer Perú for $2.5B on 5 May 2026.

Before the acquisition Perfuse Therapeutics had raised $9M across 1 funding round.

Bayer agreed to acquire Perfuse Therapeutics for up to $2.45 billion, comprising $300 million upfront and up to $2.15 billion in development, regulatory, and commercial milestones. The deal is subject to Perfuse shareholder approval and antitrust clearances. The acquisition advances Bayer's ophthalmology pipeline with Perfuse's PER-001, a Phase II asset for glaucoma and diabetic retinopathy, and two additional clinical programs for eye disorders. It marks Bayer's first pharmaceutical acquisition since 2021 and its largest drug deal in years, timed amid patent expiry and biosimilar competition for its Eylea franchise, which generated combined sales of $8.04 billion last year. Perfuse Therapeutics, headquartered in San Francisco with R&D facilities in Durham, NC, specializes in drugs for eye diseases, focusing on its sole pipeline drug and clinical programs targeting glaucoma and diabetic retinopathy.

Perfuse Therapeutics acquisition details
AcquirerDateTypePrice
  • Bayer Perú
5 May 2026Strategic M&A$2.5B

Perfuse Therapeutics Funding History

Perfuse Therapeutics has raised a total of $9M across 1 funding round.

Perfuse Therapeutics funding rounds

Perfuse Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
Jul 2020Series AAccess Biotechnology (lead); OrbiMed$9MPerfuse Therapeutics raised $9 million in a Series A funding round on July 29, 2020, led by Access Biotechnology with participation from OrbiMed and others including Camden Partners, Hatteras Venture, Lilly Asia Ventures, and We Capital. The company develops therapies to improve blood flow to the retina, targeting conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration with its lead candidate PER-001, a long-acting endothelin antagonist intravitreal implant.

Who has invested in Perfuse Therapeutics?

2 investors have backed Perfuse Therapeutics across its funding rounds, including OrbiMed and Access Biotechnology.

Lead investors include Access Biotechnology.


Perfuse Therapeutics Investors

Investors in Perfuse Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check

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Perfuse Therapeutics Competitors

Perfuse Therapeutics competitors include listed companies like China Res Double-Crane, Vera Therapeutics, Mineralys Therapeutics and Granules India, and private ones like Cambrian Biopharma and Sail Biomedicines.

Public and private companies comparable to Perfuse Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
China Res Double-CraneChinaChinaPublicly listed$1.6B$404M$2.4B1.4x
Vera TherapeuticsUnited StatesUnited StatesPublicly listed-($316M)$2.5B115.4x
Cambrian BiopharmaUnited StatesNew York City, NYPrivate--$2.5B-
Mineralys TherapeuticsUnited StatesUnited StatesPublicly listed-($171M)$2.5B-
Granules IndiaIndiaIndiaPublicly listed$557M$119M$2.5B4.2x
Sail BiomedicinesUnited StatesBoston, MAPrivate--$2.6B-
Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
China Res Double-Crane$1.6B$404M1.4x1.4x5.8x6.0x
Vera Therapeutics-($316M)-115.4x(6.5x)(4.8x)
Mineralys Therapeutics-($171M)--(10.6x)(5.7x)
Granules India$557M$119M4.6x4.2x21.2x18.4x
Viridian Therapeutics$71M($365M)26.0x51.6x(5.1x)(4.5x)
ACROBiosystems$125M$28M18.7x15.6x82.4x59.1x
Harmony Biosciences$868M$233M2.3x2.0x8.5x6.7x
Bavarian Nordic$961M$383M2.1x2.2x5.2x6.7x

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Common questions about Perfuse Therapeutics

When was Perfuse Therapeutics founded?Perfuse Therapeutics was founded in 2018.
Where is Perfuse Therapeutics headquartered?Perfuse Therapeutics is headquartered in San Francisco, CA, United States.
Is Perfuse Therapeutics publicly listed?No, Perfuse Therapeutics was acquired by Bayer Perú in May 2026.
Who acquired Perfuse Therapeutics?Perfuse Therapeutics was acquired by Bayer Perú in May 2026.
How much was Perfuse Therapeutics acquired for?Perfuse Therapeutics was acquired for $2.5B in May 2026.
How much funding has Perfuse Therapeutics raised?Perfuse Therapeutics has raised $9M across 1 funding round.
What was Perfuse Therapeutics' last funding round?Perfuse Therapeutics' last funding round was a $9M Series A in July 2020, led by Access Biotechnology.
Who are Perfuse Therapeutics' investors?Perfuse Therapeutics' investors include OrbiMed and Access Biotechnology.
Which companies are comparable to Perfuse Therapeutics?Companies comparable to Perfuse Therapeutics include China Res Double-Crane, Vera Therapeutics, Cambrian Biopharma, Mineralys Therapeutics, Granules India and Sail Biomedicines.

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