Lyndra Therapeutics Valuation, Funding & Investors

Lyndra Therapeutics is valued at $251M as of December 2023.

Last Lyndra Therapeutics valuation

$251M

Series E · Dec 2023

Last Lyndra Therapeutics funding round

$101M

Series E · Dec 2023

Cumulative funding Lyndra Therapeutics raised

$272M

across 6 funding rounds

Key investors in Lyndra Therapeutics

Lyndra Therapeutics Overview

About Lyndra Therapeutics

Lyndra Therapeutics is a Waltham, Massachusetts-headquartered biotechnology company developing ultra-long-acting oral therapies via its LYNX Coiled Wire technology platform. The firm targets central nervous system disorders with sustained-release formulations applicable to multiple therapeutic areas, enhancing medication adherence for existing drugs while reducing healthcare costs.


Founded

2015

HQ

United StatesBoston, MA

Website

lyndra.com

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Valuation

$251M (Dec 2023)

Lyndra Therapeutics Valuation

Lyndra Therapeutics is currently valued at $251M, based on its Series E in December 2023.

The $101M round was led by Sarissa Capital Management, with participation from Polaris Partners and Sun Pharma.

Lyndra Therapeutics valuation by funding round

Lyndra Therapeutics valuation by funding round
DateStageValuation
Dec 2023Series E$251M

Lyndra Therapeutics Funding History

Lyndra Therapeutics has raised a total of $272M across 6 funding rounds.

Lyndra Therapeutics' first fundraising round was a $6M Series A in July 2016. The most recent completed round was a $101M Series E in December 2023.

Lyndra Therapeutics funding rounds

Lyndra Therapeutics funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Dec 2023Series ESarissa Capital Management (lead); Polaris Partners; Sun Pharma$101M$251MLyndra Therapeutics is a clinical-stage biopharmaceutical company developing long-acting oral therapies using its proprietary LYNX drug delivery platform, which enables once-weekly dosing for medications. The company's lead candidate, LYN-005 (oral weekly risperidone), is nearing completion of a pivotal Phase 3 study for schizophrenia and schizoaffective disorder. Other candidates include LYN-045 (oral weekly dapagliflozin) for type 2 diabetes and LYN-006 (oral weekly aripiprazole). On December 21, 2023, Lyndra closed a $101 million Series E funding round led by Sarissa Capital Management, with participation from Polaris Partners and Sun Pharma. The proceeds will support pipeline advancement, particularly completing the Phase 3 trials for LYN-005 and further development of other LYNX-enabled therapies. This brings total funding raised to approximately $273 million across 9 rounds, with prior funding from sources like the Bill & Melinda Gates Foundation, NIH, AbbVie, and Gilead Sciences. As part of the deal, Sun Pharma received an exclusive license to manufacture and market LYN-005, LYN-045, and LYN-006 in six countries, including India and Brazil, pending further clinical progress. Prior to this round, Lyndra had raised about $214 million through venture financing and underwent a 23% workforce reduction in September 2023 to cut costs. The company is headquartered in Watertown, MA, with a GMP manufacturing facility in Lexington, MA.
Jun 2023Series DPolaris Partners (lead)$20M-Lyndra Therapeutics is a clinical-stage biopharmaceutical company developing long-acting oral therapies using its LYNX drug delivery platform, which enables once-weekly dosing for conditions like schizophrenia and bipolar 1 disorder. Its lead candidate, oral weekly risperidone (LYN-005), was near completion of a pivotal phase 3 study at the time of recent funding. The company focuses on psychiatry, cardiometabolic diseases, and other areas where current treatments fall short. In June 2023, Lyndra Therapeutics completed a $20.3 million or $20.35 million Series D financing round led by Polaris Partners, with participation from Quark Venture and others. This round preceded a larger $101 million Series E in December 2023 led by Sarissa Capital Management, with Sun Pharma and Polaris Partners, where Sun Pharma acquired exclusive licenses to three clinical candidates in six global markets. Proceeds from the Series D and subsequent rounds support pipeline advancement, including phase 3 trials for LYN-005. Lyndra has raised approximately $273.39 million across 9 rounds from 21 investors, including Polaris Partners, Sun Pharma, Sarissa Capital, and Gilead Sciences.
Jun 2021Series CAIG Investments (lead); Gilead Sciences; Quark Venture; Polaris Partners; Invus; HOPU Investment Management Company; Limitless Ventures; THE CATALYTIC IMPACT FOUNDATION (CIF); ApicHope Pharmaceutical; ImpactAssets; Mass General Brigham Ventures$61M-Lyndra Therapeutics is a clinical-stage biotechnology company based in Watertown, Massachusetts, pioneering a novel technology platform that transforms daily pills into once-weekly to monthly oral treatment options. The platform addresses poor medication adherence, which costs up to $300 billion annually in avoidable healthcare expenses and contributes to approximately 125,000 deaths per year in the United States. Lyndra's lead product candidate at the time was a once-weekly pill formulation for schizophrenia, which was planned to enter pivotal trials following the financing. In June 2021, Lyndra completed a $60.5 million Series C financing round led by AIG Investments, an affiliate of American International Group, Inc. The round also included new investors Yipinhong Pharmaceutical (USA) Limited, Limitless Ventures, and the Catalytic Impact Foundation with ImpactAssets, alongside existing investors including Polaris Partners, Invus, Quark Venture, Mass General Brigham Ventures, HOPU Investments, and Gilead Sciences. With this funding, Lyndra had raised approximately $250 million cumulatively across all rounds. The proceeds were intended to advance the lead product candidate into pivotal trials while the company expanded its central nervous system pipeline and evaluated high-value partnerships across various disease states. Additionally, Lyndra's investigational oral, weekly opioid use disorder treatment LYN-014 was granted Fast Track Designation by the FDA during this period.
Feb 2019Series BGilead Sciences; Quark Venture; Polaris Partners; Invus; Bill & Melinda Gates Foundation; Healthlink Capital; HOPU Investment Management Company; GF Securities; Orient Life; Mass General Brigham; Partners Innovation Fund; FUJIFILM$61M--
Apr 2017Series APolaris Partners (lead); Quark Venture; Suffolk Equity Partners; Healthlink Capital; GF Securities; Mass General Brigham; Yonghua Capital$23M-Lyndra Therapeutics, a Watertown, Massachusetts-based company founded in 2015, develops an ultra-long-acting oral drug delivery platform enabling sustained release of small molecules and peptides for seven days or more from a single capsule. The technology originated from Robert Langer's lab at MIT in collaboration with the Bill & Melinda Gates Foundation, initially for mass drug administration in developing regions, and targets neuropsychiatric disorders and other areas with adherence challenges. In April 2017, Lyndra closed a $23 million Series A round led by Polaris Partners, with participation from GF Securities, Quark Venture, Yonghua Capital, Healthlink Capital (now Mass General Brigham/Partners Healthcare), Suffolk Equity Partners, and others. The funding supported development of Lyndra's lead product candidate toward first-in-human trials later that year, expansion of manufacturing facilities, and pipeline advancement including once-weekly formulations for neuropsychology and partnerships with pharma/biotech firms. The company highlighted potential for reduced side effects, improved patient adherence, and broad applicability across indications. Subsequent rounds included a $55 million Series B in 2019 led by Polaris Partners with new investors like Gilead and the Gates Foundation for Phase II trials and manufacturing scale-up, a $60.5 million Series C, $20.3 million Series D in 2023, and $101 million Series E in 2023 led by Sarissa Capital with Sun Pharma, which licensed three candidates.
Jul 2016Series A-$6M--

Who has invested in Lyndra Therapeutics?

22 investors have backed Lyndra Therapeutics across its funding rounds, including Polaris Partners, Quark Venture, Invus, Gilead Sciences, GF Securities and HOPU Investment Management Company.

Lead investors include Sarissa Capital Management, Polaris Partners and AIG Investments.


Lyndra Therapeutics Investors

Investors in Lyndra Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Polaris PartnersUnited StatesBoston, MA5LeadApr 2017
Quark VentureCanadaVancouver3ParticipantApr 2017
Gilead SciencesUnited StatesSan Francisco, CA2ParticipantFeb 2019
InvusUnited StatesNew York City, NY2ParticipantFeb 2019
Healthlink CapitalHong KongHong Kong2ParticipantApr 2017
HOPU Investment Management CompanyChinaBeijing2ParticipantFeb 2019
GF SecuritiesChinaGuangzhou2ParticipantApr 2017
Mass General BrighamUnited StatesBoston, MA2ParticipantApr 2017
Bill & Melinda Gates FoundationUnited StatesSeattle, WA1ParticipantFeb 2019
Suffolk Equity PartnersUnited StatesUnited States1ParticipantApr 2017
Limitless VenturesUnited StatesSalt Lake City, UT1ParticipantJun 2021
Sarissa Capital ManagementUnited StatesGreenwich, CT1LeadDec 2023
THE CATALYTIC IMPACT FOUNDATION (CIF)United StatesNew York City, NY1ParticipantJun 2021

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Lyndra Therapeutics Competitors

Lyndra Therapeutics competitors include listed companies like Akebia Therapeutics, Dong-A ST and Reig Jofré, and private ones like resTORbio, SFA Therapeutics and Goldfinch Biopharma.

Public and private companies comparable to Lyndra Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Akebia TherapeuticsUnited StatesUnited StatesPublicly listed$236M$22M$251M0.7x
Dong-A STSouth KoreaSouth KoreaPublicly listed$589M$6M$251M0.8x
resTORbioUnited StatesBoston, MAPrivate--$250M-
SFA TherapeuticsUnited StatesPhiladelphia, PAPrivate--$250M-
Reig JofréSpainSpainPublicly listed$381M$32M$250M0.9x
Goldfinch BiopharmaUnited StatesUnited StatesPrivate--$252M-

Lyndra Therapeutics Public Comps

Lyndra Therapeutics is still privately-owned, but its public comps include Akebia Therapeutics, Dong-A ST, Reig Jofré, Foghorn Therapeutics, Camp4 Therapeutics, AIM Vaccine, Medipost, Acepodia, Jacobson Pharma and NervGen Pharma.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Akebia Therapeutics$236M$22M0.6x0.7x6.9x-
Dong-A ST$589M$6M0.8x0.8x84.0x10.1x
Reig Jofré$381M$32M1.0x0.9x11.8x9.3x
Foghorn Therapeutics$31M($80M)4.0x3.8x(1.6x)(1.6x)
Camp4 Therapeutics$3M($81M)48.3x27.2x(2.1x)(2.0x)
AIM Vaccine$174M($83M)2.9x3.0x(6.1x)-
Medipost$54M($59M)4.3x4.7x(3.9x)(9.7x)
Acepodia$6K($27M)25072.6x-(5.5x)-

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Common questions about Lyndra Therapeutics

When was Lyndra Therapeutics founded?Lyndra Therapeutics was founded in 2015.
Where is Lyndra Therapeutics headquartered?Lyndra Therapeutics is headquartered in Boston, MA, United States.
Is Lyndra Therapeutics publicly listed?No, Lyndra Therapeutics is a private, VC-backed company.
What is Lyndra Therapeutics' valuation?Lyndra Therapeutics was last valued at $251M in its Series E in December 2023.
How much funding has Lyndra Therapeutics raised?Lyndra Therapeutics has raised $272M across 6 funding rounds.
What was Lyndra Therapeutics' last funding round?Lyndra Therapeutics' last funding round was a $101M Series E in December 2023, led by Sarissa Capital Management.
Who are Lyndra Therapeutics' investors?Lyndra Therapeutics' investors include Polaris Partners, Quark Venture, Gilead Sciences, Invus, Healthlink Capital, HOPU Investment Management Company, GF Securities, Mass General Brigham, Bill & Melinda Gates Foundation, Suffolk Equity Partners and 12 others.
Which companies are comparable to Lyndra Therapeutics?Companies comparable to Lyndra Therapeutics include Akebia Therapeutics, Dong-A ST, resTORbio, SFA Therapeutics, Reig Jofré and Goldfinch Biopharma.

See companies similar to Lyndra Therapeutics

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