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- Lyndra Therapeutics
Lyndra Therapeutics Valuation, Funding & Investors
Lyndra Therapeutics is valued at $251M as of December 2023.
Last Lyndra Therapeutics valuation
$251M
Series E · Dec 2023
Last Lyndra Therapeutics funding round
$101M
Series E · Dec 2023
Cumulative funding Lyndra Therapeutics raised
$272M
across 6 funding rounds
Key investors in Lyndra Therapeutics
Polaris Partners
Quark Venture
Invus
Gilead Sciences
GF Securities
HOPU Investment Management Company
About Lyndra Therapeutics
Lyndra Therapeutics is a Waltham, Massachusetts-headquartered biotechnology company developing ultra-long-acting oral therapies via its LYNX Coiled Wire technology platform. The firm targets central nervous system disorders with sustained-release formulations applicable to multiple therapeutic areas, enhancing medication adherence for existing drugs while reducing healthcare costs.
Founded
2015
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Valuation
$251M (Dec 2023)
Sectors
Lyndra Therapeutics Valuation
Lyndra Therapeutics is currently valued at $251M, based on its Series E in December 2023.
The $101M round was led by Sarissa Capital Management, with participation from Polaris Partners and Sun Pharma.
Lyndra Therapeutics valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Dec 2023 | Series E | $251M |
Lyndra Therapeutics Funding History
Lyndra Therapeutics has raised a total of $272M across 6 funding rounds.
Lyndra Therapeutics' first fundraising round was a $6M Series A in July 2016. The most recent completed round was a $101M Series E in December 2023.
Lyndra Therapeutics funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Dec 2023 | Series E | Sarissa Capital Management (lead); Polaris Partners; Sun Pharma | $101M | $251M | Lyndra Therapeutics is a clinical-stage biopharmaceutical company developing long-acting oral therapies using its proprietary LYNX drug delivery platform, which enables once-weekly dosing for medications. The company's lead candidate, LYN-005 (oral weekly risperidone), is nearing completion of a pivotal Phase 3 study for schizophrenia and schizoaffective disorder. Other candidates include LYN-045 (oral weekly dapagliflozin) for type 2 diabetes and LYN-006 (oral weekly aripiprazole). On December 21, 2023, Lyndra closed a $101 million Series E funding round led by Sarissa Capital Management, with participation from Polaris Partners and Sun Pharma. The proceeds will support pipeline advancement, particularly completing the Phase 3 trials for LYN-005 and further development of other LYNX-enabled therapies. This brings total funding raised to approximately $273 million across 9 rounds, with prior funding from sources like the Bill & Melinda Gates Foundation, NIH, AbbVie, and Gilead Sciences. As part of the deal, Sun Pharma received an exclusive license to manufacture and market LYN-005, LYN-045, and LYN-006 in six countries, including India and Brazil, pending further clinical progress. Prior to this round, Lyndra had raised about $214 million through venture financing and underwent a 23% workforce reduction in September 2023 to cut costs. The company is headquartered in Watertown, MA, with a GMP manufacturing facility in Lexington, MA. |
| Jun 2023 | Series D | Polaris Partners (lead) | $20M | - | Lyndra Therapeutics is a clinical-stage biopharmaceutical company developing long-acting oral therapies using its LYNX drug delivery platform, which enables once-weekly dosing for conditions like schizophrenia and bipolar 1 disorder. Its lead candidate, oral weekly risperidone (LYN-005), was near completion of a pivotal phase 3 study at the time of recent funding. The company focuses on psychiatry, cardiometabolic diseases, and other areas where current treatments fall short. In June 2023, Lyndra Therapeutics completed a $20.3 million or $20.35 million Series D financing round led by Polaris Partners, with participation from Quark Venture and others. This round preceded a larger $101 million Series E in December 2023 led by Sarissa Capital Management, with Sun Pharma and Polaris Partners, where Sun Pharma acquired exclusive licenses to three clinical candidates in six global markets. Proceeds from the Series D and subsequent rounds support pipeline advancement, including phase 3 trials for LYN-005. Lyndra has raised approximately $273.39 million across 9 rounds from 21 investors, including Polaris Partners, Sun Pharma, Sarissa Capital, and Gilead Sciences. |
| Jun 2021 | Series C | AIG Investments (lead); Gilead Sciences; Quark Venture; Polaris Partners; Invus; HOPU Investment Management Company; Limitless Ventures; THE CATALYTIC IMPACT FOUNDATION (CIF); ApicHope Pharmaceutical; ImpactAssets; Mass General Brigham Ventures | $61M | - | Lyndra Therapeutics is a clinical-stage biotechnology company based in Watertown, Massachusetts, pioneering a novel technology platform that transforms daily pills into once-weekly to monthly oral treatment options. The platform addresses poor medication adherence, which costs up to $300 billion annually in avoidable healthcare expenses and contributes to approximately 125,000 deaths per year in the United States. Lyndra's lead product candidate at the time was a once-weekly pill formulation for schizophrenia, which was planned to enter pivotal trials following the financing. In June 2021, Lyndra completed a $60.5 million Series C financing round led by AIG Investments, an affiliate of American International Group, Inc. The round also included new investors Yipinhong Pharmaceutical (USA) Limited, Limitless Ventures, and the Catalytic Impact Foundation with ImpactAssets, alongside existing investors including Polaris Partners, Invus, Quark Venture, Mass General Brigham Ventures, HOPU Investments, and Gilead Sciences. With this funding, Lyndra had raised approximately $250 million cumulatively across all rounds. The proceeds were intended to advance the lead product candidate into pivotal trials while the company expanded its central nervous system pipeline and evaluated high-value partnerships across various disease states. Additionally, Lyndra's investigational oral, weekly opioid use disorder treatment LYN-014 was granted Fast Track Designation by the FDA during this period. |
| Feb 2019 | Series B | Gilead Sciences; Quark Venture; Polaris Partners; Invus; Bill & Melinda Gates Foundation; Healthlink Capital; HOPU Investment Management Company; GF Securities; Orient Life; Mass General Brigham; Partners Innovation Fund; FUJIFILM | $61M | - | - |
| Apr 2017 | Series A | Polaris Partners (lead); Quark Venture; Suffolk Equity Partners; Healthlink Capital; GF Securities; Mass General Brigham; Yonghua Capital | $23M | - | Lyndra Therapeutics, a Watertown, Massachusetts-based company founded in 2015, develops an ultra-long-acting oral drug delivery platform enabling sustained release of small molecules and peptides for seven days or more from a single capsule. The technology originated from Robert Langer's lab at MIT in collaboration with the Bill & Melinda Gates Foundation, initially for mass drug administration in developing regions, and targets neuropsychiatric disorders and other areas with adherence challenges. In April 2017, Lyndra closed a $23 million Series A round led by Polaris Partners, with participation from GF Securities, Quark Venture, Yonghua Capital, Healthlink Capital (now Mass General Brigham/Partners Healthcare), Suffolk Equity Partners, and others. The funding supported development of Lyndra's lead product candidate toward first-in-human trials later that year, expansion of manufacturing facilities, and pipeline advancement including once-weekly formulations for neuropsychology and partnerships with pharma/biotech firms. The company highlighted potential for reduced side effects, improved patient adherence, and broad applicability across indications. Subsequent rounds included a $55 million Series B in 2019 led by Polaris Partners with new investors like Gilead and the Gates Foundation for Phase II trials and manufacturing scale-up, a $60.5 million Series C, $20.3 million Series D in 2023, and $101 million Series E in 2023 led by Sarissa Capital with Sun Pharma, which licensed three candidates. |
| Jul 2016 | Series A | - | $6M | - | - |
Who has invested in Lyndra Therapeutics?
22 investors have backed Lyndra Therapeutics across its funding rounds, including Polaris Partners, Quark Venture, Invus, Gilead Sciences, GF Securities and HOPU Investment Management Company.
Lead investors include Sarissa Capital Management, Polaris Partners and AIG Investments.
Lyndra Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 5 | Lead | Apr 2017 | ||
| 3 | Participant | Apr 2017 | ||
| 2 | Participant | Feb 2019 | ||
| 2 | Participant | Feb 2019 | ||
| 2 | Participant | Apr 2017 | ||
| 2 | Participant | Feb 2019 | ||
| 2 | Participant | Apr 2017 | ||
| 2 | Participant | Apr 2017 | ||
| 1 | Participant | Feb 2019 | ||
| 1 | Participant | Apr 2017 | ||
| 1 | Participant | Jun 2021 | ||
| 1 | Lead | Dec 2023 | ||
| 1 | Participant | Jun 2021 | ||
This data is available for Pro users. Sign up to see all 22 Lyndra Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialLyndra Therapeutics Competitors
Lyndra Therapeutics competitors include listed companies like Akebia Therapeutics, Dong-A ST and Reig Jofré, and private ones like resTORbio, SFA Therapeutics and Goldfinch Biopharma.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $236M | $22M | $251M | 0.7x | ||
| Publicly listed | $589M | $6M | $251M | 0.8x | ||
| Private | - | - | $250M | - | ||
| Private | - | - | $250M | - | ||
| Publicly listed | $381M | $32M | $250M | 0.9x | ||
| Private | - | - | $252M | - |
Lyndra Therapeutics Public Comps
Lyndra Therapeutics is still privately-owned, but its public comps include Akebia Therapeutics, Dong-A ST, Reig Jofré, Foghorn Therapeutics, Camp4 Therapeutics, AIM Vaccine, Medipost, Acepodia, Jacobson Pharma and NervGen Pharma.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $236M | $22M | 0.6x | 0.7x | 6.9x | - | |||
| $589M | $6M | 0.8x | 0.8x | 84.0x | 10.1x | |||
| $381M | $32M | 1.0x | 0.9x | 11.8x | 9.3x | |||
| $31M | ($80M) | 4.0x | 3.8x | (1.6x) | (1.6x) | |||
| $3M | ($81M) | 48.3x | 27.2x | (2.1x) | (2.0x) | |||
| $174M | ($83M) | 2.9x | 3.0x | (6.1x) | - | |||
| $54M | ($59M) | 4.3x | 4.7x | (3.9x) | (9.7x) | |||
| $6K | ($27M) | 25072.6x | - | (5.5x) | - | |||
This data is available for Pro users. Sign up to see all Lyndra Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Lyndra Therapeutics
| When was Lyndra Therapeutics founded? | Lyndra Therapeutics was founded in 2015. |
| Where is Lyndra Therapeutics headquartered? | Lyndra Therapeutics is headquartered in Boston, MA, United States. |
| Is Lyndra Therapeutics publicly listed? | No, Lyndra Therapeutics is a private, VC-backed company. |
| What is Lyndra Therapeutics' valuation? | Lyndra Therapeutics was last valued at $251M in its Series E in December 2023. |
| How much funding has Lyndra Therapeutics raised? | Lyndra Therapeutics has raised $272M across 6 funding rounds. |
| What was Lyndra Therapeutics' last funding round? | Lyndra Therapeutics' last funding round was a $101M Series E in December 2023, led by Sarissa Capital Management. |
| Who are Lyndra Therapeutics' investors? | Lyndra Therapeutics' investors include Polaris Partners, Quark Venture, Gilead Sciences, Invus, Healthlink Capital, HOPU Investment Management Company, GF Securities, Mass General Brigham, Bill & Melinda Gates Foundation, Suffolk Equity Partners and 12 others. |
| Which companies are comparable to Lyndra Therapeutics? | Companies comparable to Lyndra Therapeutics include Akebia Therapeutics, Dong-A ST, resTORbio, SFA Therapeutics, Reig Jofré and Goldfinch Biopharma. |
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