Global Blood Therapeutics Acquisition, Valuation, Funding & Investors

Global Blood Therapeutics was acquired by Pfizer for $5.4B in August 2022, a 27.7x multiple on $195M of revenue.

Global Blood Therapeutics acquisition price

$5.4B

Acquired by Pfizer · Aug 2022

Global Blood Therapeutics revenue at acquisition

$195M

Last twelve months · Aug 2022

Global Blood Therapeutics revenue multiple at acquisition

27.7x

EV/Revenue · Aug 2022

Cumulative funding Global Blood Therapeutics raised

$48M

across 1 funding round

Global Blood Therapeutics Overview

About Global Blood Therapeutics

Global Blood Therapeutics is a San Francisco-headquartered biopharmaceutical company founded in 2012. The company developed voxelotor, branded as Oxbryta, an oral once-daily pill approved by the FDA in 2019 to treat sickle cell disease in patients aged 12 and older by increasing hemoglobin levels and reducing blood cell sickling. Pfizer acquired the company in April 2022, integrating its pipeline focused on hemoglobinopathies into broader rare disease efforts. Earlier pipeline assets included inclacumab, a monoclonal antibody for vaso-occlusive crises, evaluated in phase 3 trials.


Founded

2011

HQ

United StatesSan Francisco, CA

Website

gbt.com

Status

Acquired

Customer focus

B2B

Revenue model

Product sales

Revenue

$195M (Aug 2022)

Valuation

$5.4B (acquired Aug 2022)

Global Blood Therapeutics Acquisition

Global Blood Therapeutics was acquired by Pfizer for $5.4B on 8 August 2022.

The acquisition price implies a 27.7x revenue multiple on $195M of revenue.

Before the acquisition Global Blood Therapeutics had raised $48M across 1 funding round.

Global Blood Therapeutics acquisition details
AcquirerDateTypePriceEV/Revenue
8 Aug 2022Strategic M&A$5.4B27.7x

Global Blood Therapeutics Funding History

Global Blood Therapeutics has raised a total of $48M across 1 funding round.

Global Blood Therapeutics funding rounds

Global Blood Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
Jan 2015Series BSabby Capital; Wellington Management; RA Capital Management; Deerfield$48MGlobal Blood Therapeutics (GBT) is a biopharmaceutical company founded in 2011, focused on developing novel small molecule therapeutics for severe blood disorders, particularly sickle cell disease (SCD). Its lead candidate, GBT440 (later known as Oxbryta), was designed as an oral, once-daily HbS modifier to prevent red blood cell sickling, inhibit HbS polymerization, improve RBC deformability, and reduce blood viscosity, based on promising preclinical data presented at the 2014 ASH conference. On January 6, 2015, GBT closed a $48 million Series B financing round with investors including Wellington Management Company LLP, RA Capital, Deerfield Management, Sabby Capital, Perceptive Life Sciences (affiliate of Cowen Group), and one undisclosed public fund. The proceeds were earmarked to advance GBT440 into a Phase I/II clinical trial, marking the start of human testing for this potentially disease-modifying SCD therapy. Investors highlighted GBT's experienced team, innovative science addressing unmet needs, and strong preclinical results positioning it for success. At the time, GBT was in early-stage development with no commercial products, consistent with the absence of reported revenue, ARR, or EBITDA metrics around 2015. The company later achieved U.S. launch of Oxbryta and generated $195 million in net sales in 2021, but these figures post-date the 2015 round by years. GBT went public later in 2015, with shares surging significantly on debut, reaching a $3.5 billion market cap, and was ultimately acquired by Pfizer in 2022 for $5.4 billion enterprise value at $68.50 per share.

Who has invested in Global Blood Therapeutics?

4 investors have backed Global Blood Therapeutics across its funding rounds, including RA Capital Management, Wellington Management, Deerfield and Sabby Capital.


Global Blood Therapeutics Investors

Investors in Global Blood Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Sabby CapitalUnited StatesUpper Saddle River, NJ1ParticipantJan 2015
Wellington ManagementUnited StatesBoston, MA1ParticipantJan 2015

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Global Blood Therapeutics Competitors

Global Blood Therapeutics competitors include listed companies like Erasca, Anthem Biosciences, CRISPR Therapeutics and Xenon Pharmaceuticals, and private ones like Biocon Biologics and Intas Pharmaceuticals.

Public and private companies comparable to Global Blood Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
ErascaUnited StatesUnited StatesPublicly listed-($138M)$5.4B-
Anthem BiosciencesIndiaIndiaPublicly listed$221M$92M$5.4B22.1x
CRISPR TherapeuticsSwitzerlandSwitzerlandPublicly listed-($558M)$5.5B141.5x
Xenon PharmaceuticalsCanadaCanadaPublicly listed$8M($369M)$5.6B1495.4x
Biocon BiologicsIndiaBangalorePrivate$1.1B-$4.5B4.2x
Intas PharmaceuticalsIndiaAhmedabadPrivate$2B-$4.3B2.1x

Global Blood Therapeutics Public Comps

Global Blood Therapeutics is no longer listed, but its public comps include Erasca, Anthem Biosciences, CRISPR Therapeutics, Xenon Pharmaceuticals, Apotex Health, Ipca Laboratories, Dianthus Therapeutics, PTC Therapeutics, Ligand Pharmaceuticals and Edgewise Therapeutics.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Erasca-($138M)--(37.3x)(18.4x)
Anthem Biosciences$221M$92M24.1x22.1x57.8x56.2x
CRISPR Therapeutics-($558M)-141.5x(7.1x)(7.7x)
Xenon Pharmaceuticals$8M($369M)617.3x1495.4x(12.5x)(10.1x)
Apotex Health$2.5B$649M3.0x3.0x11.6x9.1x
Ipca Laboratories$997M$212M5.3x4.9x25.1x22.7x
Dianthus Therapeutics$2M($178M)2346.4x2479.7x(26.8x)-
PTC Therapeutics$1.7B$888M2.4x3.0x4.7x7.8x

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Common questions about Global Blood Therapeutics

When was Global Blood Therapeutics founded?Global Blood Therapeutics was founded in 2011.
Where is Global Blood Therapeutics headquartered?Global Blood Therapeutics is headquartered in San Francisco, CA, United States.
Is Global Blood Therapeutics publicly listed?No, Global Blood Therapeutics was acquired by Pfizer in August 2022.
Who acquired Global Blood Therapeutics?Global Blood Therapeutics was acquired by Pfizer in August 2022.
How much was Global Blood Therapeutics acquired for?Global Blood Therapeutics was acquired for $5.4B in August 2022, a 27.7x revenue multiple.
How much funding has Global Blood Therapeutics raised?Global Blood Therapeutics has raised $48M across 1 funding round.
What was Global Blood Therapeutics' last funding round?Global Blood Therapeutics' last funding round was a $48M Series B in January 2015.
Who are Global Blood Therapeutics' investors?Global Blood Therapeutics' investors include Sabby Capital, Wellington Management, RA Capital Management and Deerfield.
Which companies are comparable to Global Blood Therapeutics?Companies comparable to Global Blood Therapeutics include Erasca, Anthem Biosciences, CRISPR Therapeutics, Xenon Pharmaceuticals, Biocon Biologics and Intas Pharmaceuticals.

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