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- Global Blood Therapeutics
Global Blood Therapeutics Acquisition, Valuation, Funding & Investors
Global Blood Therapeutics was acquired by Pfizer for $5.4B in August 2022, a 27.7x multiple on $195M of revenue.
Global Blood Therapeutics revenue at acquisition
$195M
Last twelve months · Aug 2022
Global Blood Therapeutics revenue multiple at acquisition
27.7x
EV/Revenue · Aug 2022
Cumulative funding Global Blood Therapeutics raised
$48M
across 1 funding round
About Global Blood Therapeutics
Global Blood Therapeutics is a San Francisco-headquartered biopharmaceutical company founded in 2012. The company developed voxelotor, branded as Oxbryta, an oral once-daily pill approved by the FDA in 2019 to treat sickle cell disease in patients aged 12 and older by increasing hemoglobin levels and reducing blood cell sickling. Pfizer acquired the company in April 2022, integrating its pipeline focused on hemoglobinopathies into broader rare disease efforts. Earlier pipeline assets included inclacumab, a monoclonal antibody for vaso-occlusive crises, evaluated in phase 3 trials.
Founded
2011
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Product sales
Revenue
$195M (Aug 2022)
Valuation
$5.4B (acquired Aug 2022)
Sectors
Global Blood Therapeutics Acquisition
Global Blood Therapeutics was acquired by Pfizer for $5.4B on 8 August 2022.
The acquisition price implies a 27.7x revenue multiple on $195M of revenue.
Before the acquisition Global Blood Therapeutics had raised $48M across 1 funding round.
| Acquirer | Date | Type | Price | EV/Revenue |
|---|---|---|---|---|
| 8 Aug 2022 | Strategic M&A | $5.4B | 27.7x |
Global Blood Therapeutics Funding History
Global Blood Therapeutics has raised a total of $48M across 1 funding round.
Global Blood Therapeutics funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Jan 2015 | Series B | Sabby Capital; Wellington Management; RA Capital Management; Deerfield | $48M | Global Blood Therapeutics (GBT) is a biopharmaceutical company founded in 2011, focused on developing novel small molecule therapeutics for severe blood disorders, particularly sickle cell disease (SCD). Its lead candidate, GBT440 (later known as Oxbryta), was designed as an oral, once-daily HbS modifier to prevent red blood cell sickling, inhibit HbS polymerization, improve RBC deformability, and reduce blood viscosity, based on promising preclinical data presented at the 2014 ASH conference. On January 6, 2015, GBT closed a $48 million Series B financing round with investors including Wellington Management Company LLP, RA Capital, Deerfield Management, Sabby Capital, Perceptive Life Sciences (affiliate of Cowen Group), and one undisclosed public fund. The proceeds were earmarked to advance GBT440 into a Phase I/II clinical trial, marking the start of human testing for this potentially disease-modifying SCD therapy. Investors highlighted GBT's experienced team, innovative science addressing unmet needs, and strong preclinical results positioning it for success. At the time, GBT was in early-stage development with no commercial products, consistent with the absence of reported revenue, ARR, or EBITDA metrics around 2015. The company later achieved U.S. launch of Oxbryta and generated $195 million in net sales in 2021, but these figures post-date the 2015 round by years. GBT went public later in 2015, with shares surging significantly on debut, reaching a $3.5 billion market cap, and was ultimately acquired by Pfizer in 2022 for $5.4 billion enterprise value at $68.50 per share. |
Who has invested in Global Blood Therapeutics?
4 investors have backed Global Blood Therapeutics across its funding rounds, including RA Capital Management, Wellington Management, Deerfield and Sabby Capital.
Global Blood Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 1 | Participant | Jan 2015 | ||
| 1 | Participant | Jan 2015 | ||
This data is available for Pro users. Sign up to see all 4 Global Blood Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialGlobal Blood Therapeutics Competitors
Global Blood Therapeutics competitors include listed companies like Erasca, Anthem Biosciences, CRISPR Therapeutics and Xenon Pharmaceuticals, and private ones like Biocon Biologics and Intas Pharmaceuticals.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | - | ($138M) | $5.4B | - | ||
| Publicly listed | $221M | $92M | $5.4B | 22.1x | ||
| Publicly listed | - | ($558M) | $5.5B | 141.5x | ||
| Publicly listed | $8M | ($369M) | $5.6B | 1495.4x | ||
| Private | $1.1B | - | $4.5B | 4.2x | ||
| Private | $2B | - | $4.3B | 2.1x |
Global Blood Therapeutics Public Comps
Global Blood Therapeutics is no longer listed, but its public comps include Erasca, Anthem Biosciences, CRISPR Therapeutics, Xenon Pharmaceuticals, Apotex Health, Ipca Laboratories, Dianthus Therapeutics, PTC Therapeutics, Ligand Pharmaceuticals and Edgewise Therapeutics.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($138M) | - | - | (37.3x) | (18.4x) | |||
| $221M | $92M | 24.1x | 22.1x | 57.8x | 56.2x | |||
| - | ($558M) | - | 141.5x | (7.1x) | (7.7x) | |||
| $8M | ($369M) | 617.3x | 1495.4x | (12.5x) | (10.1x) | |||
| $2.5B | $649M | 3.0x | 3.0x | 11.6x | 9.1x | |||
| $997M | $212M | 5.3x | 4.9x | 25.1x | 22.7x | |||
| $2M | ($178M) | 2346.4x | 2479.7x | (26.8x) | - | |||
| $1.7B | $888M | 2.4x | 3.0x | 4.7x | 7.8x | |||
This data is available for Pro users. Sign up to see all Global Blood Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Global Blood Therapeutics
| When was Global Blood Therapeutics founded? | Global Blood Therapeutics was founded in 2011. |
| Where is Global Blood Therapeutics headquartered? | Global Blood Therapeutics is headquartered in San Francisco, CA, United States. |
| Is Global Blood Therapeutics publicly listed? | No, Global Blood Therapeutics was acquired by Pfizer in August 2022. |
| Who acquired Global Blood Therapeutics? | Global Blood Therapeutics was acquired by Pfizer in August 2022. |
| How much was Global Blood Therapeutics acquired for? | Global Blood Therapeutics was acquired for $5.4B in August 2022, a 27.7x revenue multiple. |
| How much funding has Global Blood Therapeutics raised? | Global Blood Therapeutics has raised $48M across 1 funding round. |
| What was Global Blood Therapeutics' last funding round? | Global Blood Therapeutics' last funding round was a $48M Series B in January 2015. |
| Who are Global Blood Therapeutics' investors? | Global Blood Therapeutics' investors include Sabby Capital, Wellington Management, RA Capital Management and Deerfield. |
| Which companies are comparable to Global Blood Therapeutics? | Companies comparable to Global Blood Therapeutics include Erasca, Anthem Biosciences, CRISPR Therapeutics, Xenon Pharmaceuticals, Biocon Biologics and Intas Pharmaceuticals. |
See companies similar to Global Blood Therapeutics
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