Bluepha Valuation, Funding & Investors

Spiber is a Tokyo-headquartered biotechnology firm founded in September 2007 producing Brewed Protein synthetic fibers via microbial fermentation of plant-based feedstocks. The proteins replace silk, wool, and petroleum plastics in apparel like The North Face Moon Parka and automotive interiors for Nissan. Spiber operates a mass production plant in Rayong, Thailand since 2021 and builds a second facility with ADM in Iowa set for 2023 operations. Partnerships with Itochu and Teijin enable commercialization of Brewed Protein polymers targeting 10,000 tons annual output by mid-decade.

Cathay Biotech Inc is engaged in research, development, production, and sales of new bio-based materials. The company owns the TERRYL brand, which focuses on bio-based polyamide fibers for textiles, and ECOPENT, which serves the engineering materials market.

Colossal Biosciences is a genetic engineering firm headquartered in Austin, Texas. Founded in 2021, it develops CRISPR-based technologies to de-extinct species including the woolly mammoth by 2028, dodo bird, and Tasmanian thylacine. The company also engineers traits into endangered animals like the Asian elephant to bolster populations against climate threats. Colossal maintains research labs across the United States and collaborates with institutions such as Harvard Medical School's George Church Lab. Its work spans genomic sequencing, stem cell reprogramming, and artificial womb development to restore ecosystems worldwide.

Sangon Biotech is a Shanghai-based biotechnology firm specializing in nucleic acid synthesis and molecular biology products. Founded in 2003 as a Sino-foreign joint venture, it manufactures DNA/RNA oligonucleotides, gene synthesis services, peptides, enzymes, reagents, lab consumables, and benchtop instruments. The company operates a production base in Songjiang Industrial Park, serving research institutions and pharmaceutical companies worldwide.

Genus PLC is an animal genetics company focused on improving cattle and pig populations to support sustainable food production. The company operates through two main business units: one providing bovine genetics mainly for dairy and beef cattle, and the other offering porcine genetics for pork production. Genus develops genetically superior breeding animals using scientific techniques. It generates revenue by selling genetics, including semen and embryos, as well as through related services under multi-year royalty agreements. The principal activities of each segment are: (a) Genus PIC porcine sales business, (b) Genus ABS: bovine sales business, and (c) Genus Research and Development: spending on research and development.

Berkeley-based UPSIDE Foods cultivates meat directly from animal cells, offering sustainable alternatives to traditional production methods without animal farming.

Believer Meats is a Jerusalem-headquartered cellular agriculture company that produces cultivated beef, chicken, lamb, and seafood through scalable bioreactor technology. The firm operates manufacturing facilities in Rehovot, Israel, and Wilson, North Carolina, focusing on distributive biomanufacturing to lower production costs. In 2023, Believer Meats rebranded from Future Meat Technologies and achieved the first ton-scale cultivated meat run globally. It collaborates with partners like Sodexo and Tyson Foods for market entry in Europe and the US. Founded in 2018, the company serves the food industry with animal-free proteins to address sustainability challenges.

FMC is a pure-play global crop protection company with a fairly balanced product portfolio across geographies and crop exposure. Through acquisitions, FMC is now one of the five largest patented crop protection companies and focuses on the development of new products, including biologicals, through its research and development pipeline.

CVR Partners LP is a manufacturer and supplier of nitrogen fertilizer products. Its principal products include Urea Ammonium Nitrate (UAN) and ammonia. The company market ammonia products to industrial and agricultural customers and UAN products to agricultural customers. The primary geographic markets for its fertilizer products are Kansas, Missouri, Nebraska, Iowa, Illinois, Colorado, and Texas. The company's product sales are heavily weighted toward UAN.

Corbion NV is a Netherlands-based company that produces food ingredients and biobased chemicals. The company distinguishes between the segments Functional Ingredients & Solutions and Health & Nutrition. The Company is a leader in sustainable bio-based ingredients and lactic acid derivatives. The company provides solutions for food preservation, health, and bioplastics through fermentation technology. Its products serve industries including food, pharmaceuticals, personal care, and packaging. Corbion focuses on innovation and sustainability to preserve food, health, and the planet. Geographically, it derives a majority of its revenue from the U.S.

Biobest is a Belgium-headquartered supplier of biological crop protection and pollination systems. Based in Westerlo, it offers bumblebees for pollination, beneficial insects and mites like Phytoseiulus persimilis, nematodes, biopesticides, sticky traps, and pheromone lures to growers internationally.

Borregaard ASA makes and sells biochemicals and biomaterials designed to replace oil-based products, It has three operating segments; BioSolutions segment develops, produces and sells biopolymers and bio vanillin from lignin used in Industries such as agrochemicals, batteries, industrial binders and construction. Bio vanillin is supplied to flavour and fragrance companies, as well as to the food and beverage industry, Biomaterials segment develops, produces and sells speciality cellulose mainly for use as a raw material in the production of cellulose ethers, cellulose acetate and other speciality products. It also includes cellulose fibrils for industrial applications, and the Fine Chemicals segment consists of fine chemical intermediates for contrast agents and bioethanol.

Meati is a Boulder, Colorado-headquartered producer of mushroom mycelium-based meat alternatives. Products like Steak, Cutlet, and Crumble replicate chicken and beef textures using whole-food fungi grown in vertical farms. Available in U.S. retailers including Kroger and Whole Foods, Meati scaled production at a Pueblo facility opened in 2022. Founded in 2016 as Emergy Foods.

Tidal Vision is a Bellingham-headquartered producer of industrial chitosan derived from Pacific Northwest crab shells. Its zero-waste enzymatic process yields high-purity biopolymer for water treatment, agriculture seed coatings, and wound dressings. The company supplies formulas to DuPont and BASF, processing over 10 million pounds of shellfish waste annually from Alaska fisheries.

Chengzhi Co Ltd, formerly Chengzhi Shareholding Co Ltd is a China-based company engaged in the businesses of clean energy, functional materials and medical care and health.

Gujarat State Fertilizers & Chemicals Ltd is a manufacturer of fertilizers and chemicals. It is structured into two operating business segments: Fertilizer Products and Industrial Products. The company operates mainly in the Indian market and there are no reportable geographical segments. It derives the majority of its revenue from the Fertilizer products segment. The products and services covered under its Fertilizer segment include Urea, Ammonium Sulphate, Di-ammonium Phosphate, Ammonium Phosphate Sulphate, and traded fertilizer products. The Industrial Products consist of Caprolactam, Nylon-6, Nylon Filament Yarn, Nylon Chips, Melamine, Methanol, and Polymer products.

Anhui Huaheng Biotechnology Co Ltd is engaged in the research and development, production and sales of bio-based products such as amino acids and other alanine products.