BlossomHill Therapeutics Valuation, Funding & Investors

BlossomHill Therapeutics is valued at $150M as of March 2021.

Last BlossomHill Therapeutics valuation

$150M

Series A · Mar 2021

Last BlossomHill Therapeutics funding round

$84M

Series B · Dec 2025

Cumulative funding BlossomHill Therapeutics raised

$257M

across 4 funding rounds

Key investors in BlossomHill Therapeutics

  • OrbiMed
  • Cormorant Asset Management
  • Vivo Capital
  • Plaisance Capital Management
  • Janus Henderson
  • BioTrack Capital

BlossomHill Therapeutics Overview

About BlossomHill Therapeutics

BlossomHill Therapeutics is a clinical-stage biopharmaceutical company based in San Diego, California, focused on designing next-generation small-molecule medicines for cancer and autoimmune diseases. Its lead programs include BH-30643, a macrocyclic OMNI-EGFR inhibitor targeting EGFR-mutant lung cancer and other malignancies, and BH-30236, a CLK inhibitor. The company was co-founded by J. Jean Cui, former CEO of Turning Point Therapeutics, which was acquired by Bristol Myers Squibb for $4.1 billion.


Founded

2020

HQ

United StatesUnited States

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Valuation

$150M (Mar 2021)

BlossomHill Therapeutics Valuation

BlossomHill Therapeutics is currently valued at $150M, based on its Series A in March 2021.

The $71M round was led by Cormorant Asset Management, OrbiMed and Vivo Capital, with participation from Hercules Bioventure Partners.

BlossomHill Therapeutics valuation by funding round

BlossomHill Therapeutics valuation by funding round
DateStageValuation
Mar 2021Series A$150M

BlossomHill Therapeutics Funding History

BlossomHill Therapeutics has raised a total of $257M across 4 funding rounds.

BlossomHill Therapeutics' first fundraising round was a $2M pre-seed round in December 2020. The most recent completed round was a $84M Series B in December 2025.

BlossomHill Therapeutics funding rounds

BlossomHill Therapeutics funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Dec 2025Series BBioTrack Capital (lead); Brahma Capital (lead); Janus Henderson (lead); Vivo Capital; Plaisance Capital Management; OrbiMed; Cormorant Asset Management$84M-BlossomHill Therapeutics is a privately-held, clinical-stage biopharmaceutical company headquartered in San Diego, California, focused on designing and developing next-generation intelligently designed cancer medicines to address treatment resistance. The company announced the closing of an $84 million Series B extension financing on December 10, 2025 (or around December 19, 2025 per some reports), led by new investors Janus Henderson Investors, Brahma Capital, and BioTrack Capital, with participation from existing investors including Cormorant Asset Management, OrbiMed, Plaisance Capital Management LLC, and Vivo Capital. This round brings the company's total capital raised to $257 million across multiple rounds. Proceeds from the financing are designated to accelerate the two lead clinical programs: BH-30643, a first-in-class macrocyclic OMNI-EGFR inhibitor targeting EGFR mutant lung cancer and other malignancies, and BH-30236, a CLK inhibitor. The funding supports further advancement of BlossomHill's wholly-owned pipeline of oncology therapeutics, leveraging its expertise in novel macrocyclic molecules to elevate standards of care in high-unmet-need cancers. Recent progress includes clinical data emerging for both lead programs, positioning the company at a critical juncture for development. BlossomHill has previously raised capital in earlier rounds, including a $100M Series B on January 2, 2024, from investors such as Colt Ventures, Amkey Ventures, Cormorant, Hercules BioVentures, OrbiMed, Plaisance, and Vivo, contributing to its total funding trajectory. The company emphasizes its track record in oncology drug design to deliver meaningful patient benefits.
Jan 2024Series BColt Ventures (lead); Hercules Partners; H&D Asset Management Company; Vivo Capital; Plaisance Capital Management; OrbiMed; Cormorant Asset Management$100M-BlossomHill Therapeutics is a clinical-stage biopharmaceutical company based in San Diego, California, focused on designing and developing next-generation small molecule medicines for cancer and autoimmune diseases, including a first-in-class macrocyclic OMNI-EGFR inhibitor (BH-30643) and a CLK inhibitor (BH-30236). The company was co-founded by J. Jean Cui, former CEO of Turning Point Therapeutics, which was acquired by Bristol Myers Squibb for $4.1 billion. The specified round matches a $100 million Series B financing closed around early 2024, led by Colt Ventures with participation from Cormorant Asset Management, H&D Asset Management Company (possibly referenced as H& in snippets), Hercules Partners (Hercules BioVentures Partners LLC), OrbiMed, Plaisance Capital Management, and Vivo Capital, bringing total funding to $173 million at that time. An earlier $71 million Series A was closed in May 2024. A later $84 million Series B extension in December 2025, led by Janus Henderson Investors, Brahma Capital, and BioTrack Capital with some overlapping investors, raised total capital to $257 million to advance clinical programs. The company plans to advance oncology programs into clinical trials, including competitors to AstraZeneca's Tagrisso for NSCLC and assets for acute myeloid leukemia, with undisclosed autoimmune projects. Proceeds from financings support pipeline acceleration and IND-enabling studies.
Mar 2021Series ACormorant Asset Management (lead); OrbiMed (lead); Vivo Capital (lead); Hercules Bioventure Partners$71M$150MBlossomHill Therapeutics is a biotechnology company headquartered in San Diego, California, focused on designing and developing small molecule medicines for cancer and autoimmune diseases, leveraging expertise from founders J. Jean Cui and Peter Li, previously of Turning Point Therapeutics. The company raised $71 million in a Series A round on March 1, 2021, with participation from Cormorant Asset Management, Hercules BioVentures Partners, OrbiMed, and Vivo Capital, achieving a post-money valuation of $150.27 million at a price per share of $2.67 with 26,613,546 shares outstanding. This followed an earlier angel round of $2 million at the end of 2020 valued at $4.44 million. The Series A funding supported the company's in-house discovery and development programs targeting high-need cancers and autoimmune diseases. BlossomHill has since advanced its pipeline, preparing to enter Phase 1 clinical trials with lead candidates like BH-30643 (OMNI-EGFR inhibitor) and BH-30236 (CLK inhibitor). In 2024, it closed a $100 million Series B led by Colt Ventures, with the same core investors plus others, bringing total capital raised to $173 million at that point, and later an $84 million Series B extension led by Janus Henderson Investors, Brahma Capital, and BioTrack Capital, pushing cumulative funding to $257 million. The company's progress is backed by a strong investor syndicate including Cormorant Asset Management, OrbiMed, and Vivo Capital, with board additions from later rounds enhancing governance.
Dec 2020Pre-seed-$2M--

Who has invested in BlossomHill Therapeutics?

11 investors have backed BlossomHill Therapeutics across its funding rounds, including OrbiMed, Cormorant Asset Management, Vivo Capital, Plaisance Capital Management, Janus Henderson and BioTrack Capital.

Lead investors include BioTrack Capital, Brahma Capital, Janus Henderson, Colt Ventures, Cormorant Asset Management and 2 other investors.


BlossomHill Therapeutics Investors

Investors in BlossomHill Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Vivo CapitalUnited StatesUnited States3LeadMar 2021
OrbiMedUnited StatesNew York City, NY3LeadMar 2021
Cormorant Asset ManagementUnited StatesBoston, MA3LeadMar 2021
Plaisance Capital ManagementUnited StatesBoston, MA2ParticipantJan 2024
Hercules PartnersUnited StatesLos Angeles, CA1ParticipantJan 2024
Colt VenturesUnited StatesDallas, TX1LeadJan 2024
H&D Asset Management CompanyTaiwanTaipei1ParticipantJan 2024
Janus HendersonUnited StatesLondon1LeadDec 2025
Brahma CapitalUnited StatesUnited States1LeadDec 2025

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BlossomHill Therapeutics Competitors

BlossomHill Therapeutics competitors include listed companies like Tenaya Therapeutics, PhotoCure, BioInvent International and Conexeu Sciences, and private ones like Immunomic Therapeutics and Gameto.

Public and private companies comparable to BlossomHill Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Immunomic TherapeuticsUnited StatesLancaster, PAPrivate--$150M-
Tenaya TherapeuticsUnited StatesUnited StatesPublicly listed-($85M)$150M26.6x
PhotoCureNorwayNorwayPublicly listed$57M$3M$149M2.0x
GametoUnited StatesNew York City, NYPrivate--$149M-
BioInvent InternationalSwedenSwedenPublicly listed$23M($34M)$151M11.1x
Conexeu SciencesUnited StatesUnited StatesPublicly listed-($4M)$151M-

BlossomHill Therapeutics Public Comps

BlossomHill Therapeutics is still privately-owned, but its public comps include Tenaya Therapeutics, PhotoCure, BioInvent International, Conexeu Sciences, Molecular Partners, Cereno Scientific, Armata Pharmaceuticals, Vytrus Biotech, NRX Pharmaceuticals and Mycenax Biotech.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Tenaya Therapeutics-($85M)-26.6x(0.9x)(0.8x)
PhotoCure$57M$3M2.3x2.0x49.1x18.7x
BioInvent International$23M($34M)5.1x11.1x(3.5x)(3.0x)
Conexeu Sciences-($4M)--(38.3x)-
Molecular Partners-($74M)--(1.0x)(1.1x)
Cereno Scientific-($8M)--(21.6x)(14.3x)
Armata Pharmaceuticals-($156M)-99.7x(2.8x)(10.7x)
Vytrus Biotech$10M$5M15.1x-30.8x-

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Common questions about BlossomHill Therapeutics

When was BlossomHill Therapeutics founded?BlossomHill Therapeutics was founded in 2020.
Where is BlossomHill Therapeutics headquartered?BlossomHill Therapeutics is headquartered in United States.
Is BlossomHill Therapeutics publicly listed?No, BlossomHill Therapeutics is a private, VC-backed company.
What is BlossomHill Therapeutics' valuation?BlossomHill Therapeutics was last valued at $150M in its Series A in March 2021.
How much funding has BlossomHill Therapeutics raised?BlossomHill Therapeutics has raised $257M across 4 funding rounds.
What was BlossomHill Therapeutics' last funding round?BlossomHill Therapeutics' last funding round was a $84M Series B in December 2025, led by BioTrack Capital, Brahma Capital and Janus Henderson.
Who are BlossomHill Therapeutics' investors?BlossomHill Therapeutics' investors include Vivo Capital, OrbiMed, Cormorant Asset Management, Plaisance Capital Management, Hercules Partners, Colt Ventures, H&D Asset Management Company, Janus Henderson, Brahma Capital, BioTrack Capital and 1 other.
Which companies are comparable to BlossomHill Therapeutics?Companies comparable to BlossomHill Therapeutics include Immunomic Therapeutics, Tenaya Therapeutics, PhotoCure, Gameto, BioInvent International and Conexeu Sciences.

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