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- BlossomHill Therapeutics
BlossomHill Therapeutics Valuation, Funding & Investors
BlossomHill Therapeutics is valued at $150M as of March 2021.
Last BlossomHill Therapeutics valuation
$150M
Series A · Mar 2021
Last BlossomHill Therapeutics funding round
$84M
Series B · Dec 2025
Cumulative funding BlossomHill Therapeutics raised
$257M
across 4 funding rounds
Key investors in BlossomHill Therapeutics
OrbiMed
Cormorant Asset Management
Vivo Capital
Plaisance Capital Management
Janus Henderson
BioTrack Capital
About BlossomHill Therapeutics
BlossomHill Therapeutics is a clinical-stage biopharmaceutical company based in San Diego, California, focused on designing next-generation small-molecule medicines for cancer and autoimmune diseases. Its lead programs include BH-30643, a macrocyclic OMNI-EGFR inhibitor targeting EGFR-mutant lung cancer and other malignancies, and BH-30236, a CLK inhibitor. The company was co-founded by J. Jean Cui, former CEO of Turning Point Therapeutics, which was acquired by Bristol Myers Squibb for $4.1 billion.
Founded
2020
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Valuation
$150M (Mar 2021)
Sectors
BlossomHill Therapeutics Valuation
BlossomHill Therapeutics is currently valued at $150M, based on its Series A in March 2021.
The $71M round was led by Cormorant Asset Management, OrbiMed and Vivo Capital, with participation from Hercules Bioventure Partners.
BlossomHill Therapeutics valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Mar 2021 | Series A | $150M |
BlossomHill Therapeutics Funding History
BlossomHill Therapeutics has raised a total of $257M across 4 funding rounds.
BlossomHill Therapeutics' first fundraising round was a $2M pre-seed round in December 2020. The most recent completed round was a $84M Series B in December 2025.
BlossomHill Therapeutics funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Dec 2025 | Series B | BioTrack Capital (lead); Brahma Capital (lead); Janus Henderson (lead); Vivo Capital; Plaisance Capital Management; OrbiMed; Cormorant Asset Management | $84M | - | BlossomHill Therapeutics is a privately-held, clinical-stage biopharmaceutical company headquartered in San Diego, California, focused on designing and developing next-generation intelligently designed cancer medicines to address treatment resistance. The company announced the closing of an $84 million Series B extension financing on December 10, 2025 (or around December 19, 2025 per some reports), led by new investors Janus Henderson Investors, Brahma Capital, and BioTrack Capital, with participation from existing investors including Cormorant Asset Management, OrbiMed, Plaisance Capital Management LLC, and Vivo Capital. This round brings the company's total capital raised to $257 million across multiple rounds. Proceeds from the financing are designated to accelerate the two lead clinical programs: BH-30643, a first-in-class macrocyclic OMNI-EGFR inhibitor targeting EGFR mutant lung cancer and other malignancies, and BH-30236, a CLK inhibitor. The funding supports further advancement of BlossomHill's wholly-owned pipeline of oncology therapeutics, leveraging its expertise in novel macrocyclic molecules to elevate standards of care in high-unmet-need cancers. Recent progress includes clinical data emerging for both lead programs, positioning the company at a critical juncture for development. BlossomHill has previously raised capital in earlier rounds, including a $100M Series B on January 2, 2024, from investors such as Colt Ventures, Amkey Ventures, Cormorant, Hercules BioVentures, OrbiMed, Plaisance, and Vivo, contributing to its total funding trajectory. The company emphasizes its track record in oncology drug design to deliver meaningful patient benefits. |
| Jan 2024 | Series B | Colt Ventures (lead); Hercules Partners; H&D Asset Management Company; Vivo Capital; Plaisance Capital Management; OrbiMed; Cormorant Asset Management | $100M | - | BlossomHill Therapeutics is a clinical-stage biopharmaceutical company based in San Diego, California, focused on designing and developing next-generation small molecule medicines for cancer and autoimmune diseases, including a first-in-class macrocyclic OMNI-EGFR inhibitor (BH-30643) and a CLK inhibitor (BH-30236). The company was co-founded by J. Jean Cui, former CEO of Turning Point Therapeutics, which was acquired by Bristol Myers Squibb for $4.1 billion. The specified round matches a $100 million Series B financing closed around early 2024, led by Colt Ventures with participation from Cormorant Asset Management, H&D Asset Management Company (possibly referenced as H& in snippets), Hercules Partners (Hercules BioVentures Partners LLC), OrbiMed, Plaisance Capital Management, and Vivo Capital, bringing total funding to $173 million at that time. An earlier $71 million Series A was closed in May 2024. A later $84 million Series B extension in December 2025, led by Janus Henderson Investors, Brahma Capital, and BioTrack Capital with some overlapping investors, raised total capital to $257 million to advance clinical programs. The company plans to advance oncology programs into clinical trials, including competitors to AstraZeneca's Tagrisso for NSCLC and assets for acute myeloid leukemia, with undisclosed autoimmune projects. Proceeds from financings support pipeline acceleration and IND-enabling studies. |
| Mar 2021 | Series A | Cormorant Asset Management (lead); OrbiMed (lead); Vivo Capital (lead); Hercules Bioventure Partners | $71M | $150M | BlossomHill Therapeutics is a biotechnology company headquartered in San Diego, California, focused on designing and developing small molecule medicines for cancer and autoimmune diseases, leveraging expertise from founders J. Jean Cui and Peter Li, previously of Turning Point Therapeutics. The company raised $71 million in a Series A round on March 1, 2021, with participation from Cormorant Asset Management, Hercules BioVentures Partners, OrbiMed, and Vivo Capital, achieving a post-money valuation of $150.27 million at a price per share of $2.67 with 26,613,546 shares outstanding. This followed an earlier angel round of $2 million at the end of 2020 valued at $4.44 million. The Series A funding supported the company's in-house discovery and development programs targeting high-need cancers and autoimmune diseases. BlossomHill has since advanced its pipeline, preparing to enter Phase 1 clinical trials with lead candidates like BH-30643 (OMNI-EGFR inhibitor) and BH-30236 (CLK inhibitor). In 2024, it closed a $100 million Series B led by Colt Ventures, with the same core investors plus others, bringing total capital raised to $173 million at that point, and later an $84 million Series B extension led by Janus Henderson Investors, Brahma Capital, and BioTrack Capital, pushing cumulative funding to $257 million. The company's progress is backed by a strong investor syndicate including Cormorant Asset Management, OrbiMed, and Vivo Capital, with board additions from later rounds enhancing governance. |
| Dec 2020 | Pre-seed | - | $2M | - | - |
Who has invested in BlossomHill Therapeutics?
11 investors have backed BlossomHill Therapeutics across its funding rounds, including OrbiMed, Cormorant Asset Management, Vivo Capital, Plaisance Capital Management, Janus Henderson and BioTrack Capital.
Lead investors include BioTrack Capital, Brahma Capital, Janus Henderson, Colt Ventures, Cormorant Asset Management and 2 other investors.
BlossomHill Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Mar 2021 | ||
| 3 | Lead | Mar 2021 | ||
| 3 | Lead | Mar 2021 | ||
| 2 | Participant | Jan 2024 | ||
| 1 | Participant | Jan 2024 | ||
| 1 | Lead | Jan 2024 | ||
| 1 | Participant | Jan 2024 | ||
| 1 | Lead | Dec 2025 | ||
| 1 | Lead | Dec 2025 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialBlossomHill Therapeutics Competitors
BlossomHill Therapeutics competitors include listed companies like Tenaya Therapeutics, PhotoCure, BioInvent International and Conexeu Sciences, and private ones like Immunomic Therapeutics and Gameto.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Private | - | - | $150M | - | ||
| Publicly listed | - | ($85M) | $150M | 26.6x | ||
| Publicly listed | $57M | $3M | $149M | 2.0x | ||
| Private | - | - | $149M | - | ||
| Publicly listed | $23M | ($34M) | $151M | 11.1x | ||
| Publicly listed | - | ($4M) | $151M | - |
BlossomHill Therapeutics Public Comps
BlossomHill Therapeutics is still privately-owned, but its public comps include Tenaya Therapeutics, PhotoCure, BioInvent International, Conexeu Sciences, Molecular Partners, Cereno Scientific, Armata Pharmaceuticals, Vytrus Biotech, NRX Pharmaceuticals and Mycenax Biotech.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($85M) | - | 26.6x | (0.9x) | (0.8x) | |||
| $57M | $3M | 2.3x | 2.0x | 49.1x | 18.7x | |||
| $23M | ($34M) | 5.1x | 11.1x | (3.5x) | (3.0x) | |||
| - | ($4M) | - | - | (38.3x) | - | |||
| - | ($74M) | - | - | (1.0x) | (1.1x) | |||
| - | ($8M) | - | - | (21.6x) | (14.3x) | |||
| - | ($156M) | - | 99.7x | (2.8x) | (10.7x) | |||
| $10M | $5M | 15.1x | - | 30.8x | - | |||
This data is available for Pro users. Sign up to see all BlossomHill Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about BlossomHill Therapeutics
| When was BlossomHill Therapeutics founded? | BlossomHill Therapeutics was founded in 2020. |
| Where is BlossomHill Therapeutics headquartered? | BlossomHill Therapeutics is headquartered in United States. |
| Is BlossomHill Therapeutics publicly listed? | No, BlossomHill Therapeutics is a private, VC-backed company. |
| What is BlossomHill Therapeutics' valuation? | BlossomHill Therapeutics was last valued at $150M in its Series A in March 2021. |
| How much funding has BlossomHill Therapeutics raised? | BlossomHill Therapeutics has raised $257M across 4 funding rounds. |
| What was BlossomHill Therapeutics' last funding round? | BlossomHill Therapeutics' last funding round was a $84M Series B in December 2025, led by BioTrack Capital, Brahma Capital and Janus Henderson. |
| Who are BlossomHill Therapeutics' investors? | BlossomHill Therapeutics' investors include Vivo Capital, OrbiMed, Cormorant Asset Management, Plaisance Capital Management, Hercules Partners, Colt Ventures, H&D Asset Management Company, Janus Henderson, Brahma Capital, BioTrack Capital and 1 other. |
| Which companies are comparable to BlossomHill Therapeutics? | Companies comparable to BlossomHill Therapeutics include Immunomic Therapeutics, Tenaya Therapeutics, PhotoCure, Gameto, BioInvent International and Conexeu Sciences. |
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