Arvelle Therapeutics Acquisition, Valuation, Funding & Investors

Arvelle Therapeutics was acquired by Angelini Pharma for $960M in January 2021.

Arvelle Therapeutics acquisition price

$960M

Acquired by Angelini Pharma · Jan 2021

Cumulative funding Arvelle Therapeutics raised

$222M

across 2 funding rounds

Key investors in Arvelle Therapeutics

  • EQT
  • Andera Partners
  • Novaquest Capital Management
  • H.I.G. BioHealth Partners
  • BPV Capital Management
  • F-Prime
  • KB Investment

Arvelle Therapeutics Overview

About Arvelle Therapeutics

Arvelle Therapeutics is a biopharmaceutical firm dedicated to treatments for central nervous system disorders. The company advances therapies targeting unmet needs in neurology from its base in Switzerland. Acquired by Pfizer in 2021, Arvelle previously developed cenobamate for epilepsy, approved in Europe and the U.S. under the brand Xcopri.


Founded

2019

HQ

SwitzerlandBasel

Status

Acquired

Customer focus

B2C

Revenue model

Product sales

Valuation

$960M (acquired Jan 2021)

Arvelle Therapeutics Acquisition

Arvelle Therapeutics was acquired by Angelini Pharma for $960M on 4 January 2021.

Before the acquisition Arvelle Therapeutics had raised $222M across 2 funding rounds.

Arvelle Therapeutics acquisition details
AcquirerDateTypePrice
  • Angelini Pharma
4 Jan 2021Strategic M&A$960M

Arvelle Therapeutics Funding History

Arvelle Therapeutics has raised a total of $222M across 2 funding rounds.

Arvelle Therapeutics' first fundraising round was a $180M Series A in February 2019. The most recent completed round was a $43M Series A in May 2020.

Arvelle Therapeutics funding rounds

Arvelle Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
May 2020Series AKB Investment; EQT; BPV Capital Management; F-Prime; Novaquest Capital Management; Andera Partners; H.I.G. BioHealth Partners$43MArvelle Therapeutics is a Swiss-based emerging biopharmaceutical company focused on developing and commercializing cenobamate, an investigational antiepileptic drug for the European market. The company was founded in early 2019 and entered an exclusive licensing agreement with SK Biopharmaceuticals to develop and commercialize cenobamate in Europe, with SK receiving a $100 million upfront payment and eligibility for up to $430 million in regulatory and commercial milestone payments. In February 2019, Arvelle closed a Series A financing round of $180 million led by LSP, with participation from NovaQuest Capital Management, BRV Capital Management, Andera Partners, and H.I.G. BioHealth Partners. The final tranche of the Series A closed on May 26, 2020, adding $42.7 million to bring total capital raised to $207.8 million. This $207.8 million represented one of the largest initial financing commitments for a European-focused biopharmaceutical company at the time. Arvelle's lead asset, cenobamate, received FDA approval in November 2019 for treatment of partial onset seizures in adult patients, and the company successfully triggered the final Series A tranche upon filing and validation of its Marketing Authorization Application (MAA) with European regulatory authorities. On January 4, 2021, Italian pharmaceutical company Angelini Pharma acquired Arvelle Therapeutics for a total aggregate valuation of up to $960 million, consisting of $610 million due upon EMA approval and an additional $350 million contingent on achieving specified revenue targets.
Feb 2019Series AEQT (lead); BPV Capital Management; Novaquest Capital Management; Andera Partners; H.I.G. BioHealth Partners$180MArvelle Therapeutics, founded in 2019 and based in Zug, Switzerland, was a biopharmaceutical company focused on developing and commercializing innovative therapies for central nervous system (CNS) disorders, particularly cenobamate, an investigational anti-epileptic drug licensed from SK Biopharmaceuticals for the European market. The company was spun off from Axovant and targeted patients with epilepsy, specifically partial-onset seizures. In February 2019, Arvelle raised approximately $180 million in a Series A round led by LSP (part of EQT Life Sciences), with participation from Andera Partners, BRV Capital Management (likely BPV Capital Management), NovaQuest Capital Management, and H.I.G. BioHealth Partners, among others including F-Prime Capital and KB Investments. Sources report the total initial financing as $207.8 million, one of the largest for a European-focused biopharma startup. This funding supported the development and commercialization of cenobamate, which had advanced to NDA acceptance by US regulators by SK Biopharma; Arvelle paid SK $100 million upfront, with potential milestones up to $430 million total. Axovant retained a 5% stake. The company progressed with cenobamate, planning European launch post-EMA approval expected in 2021. Arvelle was acquired by Angelini Pharma in January 2021 in an all-cash deal valued at up to $960 million ($610 million upfront plus $350 million contingent on revenue milestones), with SK Biopharma selling its 12% stake but retaining license payments and revenue shares assumed by Angelini. Post-acquisition, Angelini Pharma gained exclusive rights to commercialize cenobamate in the EU, EEA, UK, and Switzerland, expanding its CNS portfolio and opening new affiliates.

Who has invested in Arvelle Therapeutics?

7 investors have backed Arvelle Therapeutics across its funding rounds, including EQT, Andera Partners, Novaquest Capital Management, H.I.G. BioHealth Partners, BPV Capital Management and F-Prime.

Lead investors include EQT.


Arvelle Therapeutics Investors

Investors in Arvelle Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
EQTSwedenStockholm2LeadFeb 2019
BPV Capital ManagementUnited StatesKnoxville, TN2ParticipantFeb 2019
Novaquest Capital ManagementUnited StatesRaleigh, NC2ParticipantFeb 2019
Andera PartnersFranceParis2ParticipantFeb 2019
H.I.G. BioHealth PartnersUnited StatesMiami, FL2ParticipantFeb 2019

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Arvelle Therapeutics Competitors

Arvelle Therapeutics competitors include listed companies like Solid Biosciences, Chengdu Kanghua, Kaken Pharmaceutical and Pacira BioSciences, and private ones like InduPro and Bionyra.

Public and private companies comparable to Arvelle Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Solid BiosciencesUnited StatesUnited StatesPublicly listed-($183M)$951M-
InduProUnited StatesSeattle, WAPrivate--$950M-
Chengdu KanghuaChinaChinaPublicly listed$174M$50M$974M4.4x
Kaken PharmaceuticalJapanJapanPublicly listed$494M$35M$975M1.3x
Pacira BioSciencesUnited StatesUnited StatesPublicly listed$726M$100M$977M1.5x
BionyraFranceParisPrivate--$985M-

Arvelle Therapeutics Public Comps

Arvelle Therapeutics is no longer listed, but its public comps include Solid Biosciences, Chengdu Kanghua, Kaken Pharmaceutical, Pacira BioSciences, Changchun BCHT, Zhejiang Ausun, SpyGlass Pharma, Adlai Nortye, Mega Lifesciences and Daewoong Pharmaceutical.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Solid Biosciences-($183M)--(3.2x)(2.7x)
Chengdu Kanghua$174M$50M4.7x4.4x16.6x16.3x
Kaken Pharmaceutical$494M$35M1.4x1.3x19.4x15.4x
Pacira BioSciences$726M$100M1.6x1.5x11.4x6.2x
Changchun BCHT$90M($30M)10.7x10.9x(32.5x)(36.5x)
Zhejiang Ausun$118M$29M7.1x6.5x28.9x15.3x
SpyGlass Pharma-($42M)--(17.7x)(11.4x)
Adlai Nortye$5M($33M)155.6x54.3x(23.8x)(23.9x)

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Common questions about Arvelle Therapeutics

When was Arvelle Therapeutics founded?Arvelle Therapeutics was founded in 2019.
Where is Arvelle Therapeutics headquartered?Arvelle Therapeutics is headquartered in Basel, Switzerland.
Is Arvelle Therapeutics publicly listed?No, Arvelle Therapeutics was acquired by Angelini Pharma in January 2021.
Who acquired Arvelle Therapeutics?Arvelle Therapeutics was acquired by Angelini Pharma in January 2021.
How much was Arvelle Therapeutics acquired for?Arvelle Therapeutics was acquired for $960M in January 2021.
How much funding has Arvelle Therapeutics raised?Arvelle Therapeutics has raised $222M across 2 funding rounds.
What was Arvelle Therapeutics' last funding round?Arvelle Therapeutics' last funding round was a $43M Series A in May 2020.
Who are Arvelle Therapeutics' investors?Arvelle Therapeutics' investors include EQT, BPV Capital Management, Novaquest Capital Management, Andera Partners, H.I.G. BioHealth Partners, KB Investment and F-Prime.
Which companies are comparable to Arvelle Therapeutics?Companies comparable to Arvelle Therapeutics include Solid Biosciences, InduPro, Chengdu Kanghua, Kaken Pharmaceutical, Pacira BioSciences and Bionyra.

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