Aiolos Bio Acquisition, Valuation, Funding & Investors

Aiolos Bio was acquired by GSK for $1.4B in January 2024.

Aiolos Bio acquisition price

$1.4B

Acquired by GSK · Jan 2024

Cumulative funding Aiolos Bio raised

$245M

across 1 funding round

Key investors in Aiolos Bio

  • RA Capital Management
  • Bain Capital
  • Atlas Venture
  • Forbion Capital Partners
  • Sofinnova Investments

Aiolos Bio Overview

About Aiolos Bio

Aiolos Bio is a San Diego-based biotechnology company developing monoclonal antibody therapies for respiratory diseases including moderate-to-severe asthma and immune-mediated conditions. Its lead candidate AIO-001 requires dosing every six months and targets TSLP signaling pathways. The firm advances clinical programs through partnerships with contract research organizations in the United States and Europe.


Founded

2023

HQ

United StatesSan Francisco, CA

Status

Acquired

Customer focus

B2B

Revenue model

Licensing

Valuation

$1.4B (acquired Jan 2024)

Aiolos Bio Acquisition

Aiolos Bio was acquired by GSK for $1.4B on 9 January 2024.

Before the acquisition Aiolos Bio had raised $245M across 1 funding round.

Aiolos Bio, a UK-based clinical-stage biopharmaceutical company founded in 2023, develops therapies for patients with inflammatory and respiratory conditions, centered on AIO-001, a Phase II-ready long-acting monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), a key driver of asthma inflammation. The antibody binds the TSLP ligand to block its signaling pathway, offering potential dosing every six months due to extended half-life and high potency, addressing needs in severe asthma patients with low Type 2 inflammation, comprising about 40% of cases, and possible expansion to nasal polyps and chronic rhinosinusitis. Aiolos launched in October 2023 with $245 million Series A financing led by Forbion, Atlas Venture, Bain Capital Life Sciences, Sofinnova Investments, and RA Capital Management; AIO-001 was exclusively licensed from Jiangsu Hengrui Pharmaceuticals for development and commercialization outside Greater China. GlaxoSmithKline (GSK), a global leader in respiratory therapies with a portfolio targeting high eosinophil levels or high T2 inflammation diseases, acquired Aiolos Bio to expand its respiratory biologics pipeline by adding AIO-001, which reaches low T2 inflammation patients underserved by current options. The deal, announced January 9, 2024, and completed February 16, 2024, subject to antitrust clearance including Hart-Scott-Rodino Act, includes $1 billion upfront payment plus up to $400 million in success-based regulatory milestones, with GSK assuming further milestone payments and tiered royalties to Hengrui. Strategic rationale centers on AIO-001's potential to redefine asthma care standards through infrequent dosing and broader patient reach, building on GSK's RSV vaccine success amid industry trends of pipeline fortification via acquisitions to compete with Amgen and AstraZeneca in respiratory markets.

Aiolos Bio acquisition details
AcquirerDateTypePrice
9 Jan 2024Strategic M&A$1.4B

Aiolos Bio Funding History

Aiolos Bio has raised a total of $245M across 1 funding round.

Aiolos Bio funding rounds

Aiolos Bio funding rounds
DateStageInvestorsRaisedDeal Summary
Oct 2023Series AAtlas Venture (lead); Bain Capital (lead); Forbion Capital Partners (lead); Sofinnova Investments (lead); RA Capital Management$245MAiolos Bio launched on October 24, 2023, as a clinical-stage biopharmaceutical company focused on respiratory and inflammatory conditions, raising an oversubscribed $245 million Series A financing co-led by Atlas Venture, Bain Capital Life Sciences, Forbion, and Sofinnova Investments, with participation from RA Capital Management. The funds support advancing its lead asset, AIO-001, an anti-TSLP antibody licensed from Jiangsu Hengrui Pharmaceuticals, into a Phase 2 trial for moderate-to-severe asthma patients. AIO-001 demonstrated high potency, long half-life, safety, tolerability, pharmacokinetics, and biological activity in preclinical studies and Phase 1 trials in healthy volunteers and asthma patients, with potential for twice-yearly dosing positioning it as best-in-class against competitors like Tezspire from Amgen and AstraZeneca. The company, based in San Francisco and London, is led by CEO Khurem Farooq, former CEO of Novartis-acquired Gyroscope Therapeutics, with John F. Milligan, ex-Gilead CEO, as Chairman, and co-founder Tony Adamis, M.D., on the board. Investors were attracted by the Phase 2-ready asset, strong management, and expansion potential into COPD and chronic spontaneous urticaria, though only preclinical data exists for those indications. The round was among the largest biotech Series A financings of 2023, highlighting investor appetite for advanced respiratory assets amid a competitive field including Upstream Bio. Subsequently, in early 2024, GSK acquired Aiolos for $1 billion upfront plus up to $400 million in milestones, providing a quick exit for backers just months after launch.

Who has invested in Aiolos Bio?

5 investors have backed Aiolos Bio across its funding rounds, including RA Capital Management, Bain Capital, Atlas Venture, Forbion Capital Partners and Sofinnova Investments.

Lead investors include Atlas Venture, Bain Capital, Forbion Capital Partners and Sofinnova Investments.


Aiolos Bio Investors

Investors in Aiolos Bio by funding rounds participated
InvestorHQRoundsRoleFirst check
Atlas VentureUnited StatesUnited States1LeadOct 2023
RA Capital ManagementUnited StatesBoston, MA1ParticipantOct 2023
Sofinnova InvestmentsUnited StatesSan Francisco, CA1LeadOct 2023

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Aiolos Bio Competitors

Aiolos Bio competitors include listed companies like First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health and Pacific Shuanglin, and private ones like Moonlight Therapeutics and Grupo Cimed.

Public and private companies comparable to Aiolos Bio
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Moonlight TherapeuticsUnited StatesAtlanta, GAPrivate--$1.4B-
First Tracks BiotherapeuticsUnited StatesUnited StatesPublicly listed-($179M)$1.4B-
ArriVent BioPharmaUnited StatesUnited StatesPublicly listed-($178M)$1.4B-
Phibro Animal HealthUnited StatesUnited StatesPublicly listed$1.5B$231M$1.4B1.4x
Pacific ShuanglinChinaChinaPublicly listed$393M$90M$1.4B-
Grupo CimedBrazilSão PauloPrivate--$1.4B-
Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
First Tracks Biotherapeutics-($179M)--(6.9x)(7.6x)
ArriVent BioPharma-($178M)--(5.8x)(5.2x)
Phibro Animal Health$1.5B$231M1.4x1.4x9.1x8.2x
Pacific Shuanglin$393M$90M3.6x-15.8x-
Damora Therapeutics-($211M)--(4.7x)(6.1x)
SOTHEMA$340M$75M4.3x4.2x19.6x-
Zhejiang Jolly$453M$126M3.1x2.7x11.2x10.4x
Cullinan Therapeutics-($242M)-115.6x(4.3x)(5.0x)

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Common questions about Aiolos Bio

When was Aiolos Bio founded?Aiolos Bio was founded in 2023.
Where is Aiolos Bio headquartered?Aiolos Bio is headquartered in San Francisco, CA, United States.
Is Aiolos Bio publicly listed?No, Aiolos Bio was acquired by GSK in January 2024.
Who acquired Aiolos Bio?Aiolos Bio was acquired by GSK in January 2024.
How much was Aiolos Bio acquired for?Aiolos Bio was acquired for $1.4B in January 2024.
How much funding has Aiolos Bio raised?Aiolos Bio has raised $245M across 1 funding round.
What was Aiolos Bio's last funding round?Aiolos Bio's last funding round was a $245M Series A in October 2023, led by Atlas Venture, Bain Capital, Forbion Capital Partners and Sofinnova Investments.
Who are Aiolos Bio's investors?Aiolos Bio's investors include Atlas Venture, RA Capital Management, Sofinnova Investments, Bain Capital and Forbion Capital Partners.
Which companies are comparable to Aiolos Bio?Companies comparable to Aiolos Bio include Moonlight Therapeutics, First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health, Pacific Shuanglin and Grupo Cimed.

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