- Companies
- Aiolos Bio
Aiolos Bio Acquisition, Valuation, Funding & Investors
Aiolos Bio was acquired by GSK for $1.4B in January 2024.
Cumulative funding Aiolos Bio raised
$245M
across 1 funding round
Key investors in Aiolos Bio
RA Capital Management
Bain Capital
Atlas Venture
Forbion Capital Partners
Sofinnova Investments
About Aiolos Bio
Aiolos Bio is a San Diego-based biotechnology company developing monoclonal antibody therapies for respiratory diseases including moderate-to-severe asthma and immune-mediated conditions. Its lead candidate AIO-001 requires dosing every six months and targets TSLP signaling pathways. The firm advances clinical programs through partnerships with contract research organizations in the United States and Europe.
Founded
2023
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Licensing
Valuation
$1.4B (acquired Jan 2024)
Sectors
Aiolos Bio Acquisition
Aiolos Bio was acquired by GSK for $1.4B on 9 January 2024.
Before the acquisition Aiolos Bio had raised $245M across 1 funding round.
Aiolos Bio, a UK-based clinical-stage biopharmaceutical company founded in 2023, develops therapies for patients with inflammatory and respiratory conditions, centered on AIO-001, a Phase II-ready long-acting monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), a key driver of asthma inflammation. The antibody binds the TSLP ligand to block its signaling pathway, offering potential dosing every six months due to extended half-life and high potency, addressing needs in severe asthma patients with low Type 2 inflammation, comprising about 40% of cases, and possible expansion to nasal polyps and chronic rhinosinusitis. Aiolos launched in October 2023 with $245 million Series A financing led by Forbion, Atlas Venture, Bain Capital Life Sciences, Sofinnova Investments, and RA Capital Management; AIO-001 was exclusively licensed from Jiangsu Hengrui Pharmaceuticals for development and commercialization outside Greater China. GlaxoSmithKline (GSK), a global leader in respiratory therapies with a portfolio targeting high eosinophil levels or high T2 inflammation diseases, acquired Aiolos Bio to expand its respiratory biologics pipeline by adding AIO-001, which reaches low T2 inflammation patients underserved by current options. The deal, announced January 9, 2024, and completed February 16, 2024, subject to antitrust clearance including Hart-Scott-Rodino Act, includes $1 billion upfront payment plus up to $400 million in success-based regulatory milestones, with GSK assuming further milestone payments and tiered royalties to Hengrui. Strategic rationale centers on AIO-001's potential to redefine asthma care standards through infrequent dosing and broader patient reach, building on GSK's RSV vaccine success amid industry trends of pipeline fortification via acquisitions to compete with Amgen and AstraZeneca in respiratory markets.
| Acquirer | Date | Type | Price |
|---|---|---|---|
| 9 Jan 2024 | Strategic M&A | $1.4B |
Aiolos Bio Funding History
Aiolos Bio has raised a total of $245M across 1 funding round.
Aiolos Bio funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Oct 2023 | Series A | Atlas Venture (lead); Bain Capital (lead); Forbion Capital Partners (lead); Sofinnova Investments (lead); RA Capital Management | $245M | Aiolos Bio launched on October 24, 2023, as a clinical-stage biopharmaceutical company focused on respiratory and inflammatory conditions, raising an oversubscribed $245 million Series A financing co-led by Atlas Venture, Bain Capital Life Sciences, Forbion, and Sofinnova Investments, with participation from RA Capital Management. The funds support advancing its lead asset, AIO-001, an anti-TSLP antibody licensed from Jiangsu Hengrui Pharmaceuticals, into a Phase 2 trial for moderate-to-severe asthma patients. AIO-001 demonstrated high potency, long half-life, safety, tolerability, pharmacokinetics, and biological activity in preclinical studies and Phase 1 trials in healthy volunteers and asthma patients, with potential for twice-yearly dosing positioning it as best-in-class against competitors like Tezspire from Amgen and AstraZeneca. The company, based in San Francisco and London, is led by CEO Khurem Farooq, former CEO of Novartis-acquired Gyroscope Therapeutics, with John F. Milligan, ex-Gilead CEO, as Chairman, and co-founder Tony Adamis, M.D., on the board. Investors were attracted by the Phase 2-ready asset, strong management, and expansion potential into COPD and chronic spontaneous urticaria, though only preclinical data exists for those indications. The round was among the largest biotech Series A financings of 2023, highlighting investor appetite for advanced respiratory assets amid a competitive field including Upstream Bio. Subsequently, in early 2024, GSK acquired Aiolos for $1 billion upfront plus up to $400 million in milestones, providing a quick exit for backers just months after launch. |
Who has invested in Aiolos Bio?
5 investors have backed Aiolos Bio across its funding rounds, including RA Capital Management, Bain Capital, Atlas Venture, Forbion Capital Partners and Sofinnova Investments.
Lead investors include Atlas Venture, Bain Capital, Forbion Capital Partners and Sofinnova Investments.
Aiolos Bio Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 1 | Lead | Oct 2023 | ||
| 1 | Participant | Oct 2023 | ||
| 1 | Lead | Oct 2023 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialAiolos Bio Competitors
Aiolos Bio competitors include listed companies like First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health and Pacific Shuanglin, and private ones like Moonlight Therapeutics and Grupo Cimed.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Private | - | - | $1.4B | - | ||
| Publicly listed | - | ($179M) | $1.4B | - | ||
| Publicly listed | - | ($178M) | $1.4B | - | ||
| Publicly listed | $1.5B | $231M | $1.4B | 1.4x | ||
| Publicly listed | $393M | $90M | $1.4B | - | ||
| Private | - | - | $1.4B | - |
Aiolos Bio Public Comps
Aiolos Bio is no longer listed, but its public comps include First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health, Pacific Shuanglin, Damora Therapeutics, SOTHEMA, Zhejiang Jolly, Cullinan Therapeutics, Ascentage Pharma Group and Ultragenyx.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($179M) | - | - | (6.9x) | (7.6x) | |||
| - | ($178M) | - | - | (5.8x) | (5.2x) | |||
| $1.5B | $231M | 1.4x | 1.4x | 9.1x | 8.2x | |||
| $393M | $90M | 3.6x | - | 15.8x | - | |||
| - | ($211M) | - | - | (4.7x) | (6.1x) | |||
| $340M | $75M | 4.3x | 4.2x | 19.6x | - | |||
| $453M | $126M | 3.1x | 2.7x | 11.2x | 10.4x | |||
| - | ($242M) | - | 115.6x | (4.3x) | (5.0x) | |||
This data is available for Pro users. Sign up to see all Aiolos Bio competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Aiolos Bio
| When was Aiolos Bio founded? | Aiolos Bio was founded in 2023. |
| Where is Aiolos Bio headquartered? | Aiolos Bio is headquartered in San Francisco, CA, United States. |
| Is Aiolos Bio publicly listed? | No, Aiolos Bio was acquired by GSK in January 2024. |
| Who acquired Aiolos Bio? | Aiolos Bio was acquired by GSK in January 2024. |
| How much was Aiolos Bio acquired for? | Aiolos Bio was acquired for $1.4B in January 2024. |
| How much funding has Aiolos Bio raised? | Aiolos Bio has raised $245M across 1 funding round. |
| What was Aiolos Bio's last funding round? | Aiolos Bio's last funding round was a $245M Series A in October 2023, led by Atlas Venture, Bain Capital, Forbion Capital Partners and Sofinnova Investments. |
| Who are Aiolos Bio's investors? | Aiolos Bio's investors include Atlas Venture, RA Capital Management, Sofinnova Investments, Bain Capital and Forbion Capital Partners. |
| Which companies are comparable to Aiolos Bio? | Companies comparable to Aiolos Bio include Moonlight Therapeutics, First Tracks Biotherapeutics, ArriVent BioPharma, Phibro Animal Health, Pacific Shuanglin and Grupo Cimed. |
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