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- Shape Therapeutics
Shape Therapeutics Valuation, Funding & Investors
Shape Therapeutics is valued at $143M as of November 2019.
Last Shape Therapeutics valuation
$143M
Series A · Nov 2019
Last Shape Therapeutics funding round
$112M
Series B · Jul 2021
Cumulative funding Shape Therapeutics raised
$148M
across 2 funding rounds
Key investors in Shape Therapeutics
New Enterprise Associates
Mission BioCapital
Ling Wong
Cherubic Ventures
Decheng Capital
Tectonic Capital
About Shape Therapeutics
Shape Therapeutics is a Seattle-headquartered biotechnology company pioneering RNA editing and gene therapy platforms. Its technologies address neurodegenerative disorders, metabolic conditions, and rare genetic diseases through advanced payloads, delivery systems, and manufacturing processes.
Founded
2018
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Licensing
Valuation
$143M (Nov 2019)
Shape Therapeutics Valuation
Shape Therapeutics is currently valued at $143M, based on its Series A in November 2019.
The $36M round was led by New Enterprise Associates, with participation from Tectonic Capital, CureDuchenne Ventures, Ling Wong and Mission BioCapital.
Shape Therapeutics valuation by funding round
| Date | Stage | Valuation |
|---|---|---|
| Nov 2019 | Series A | $143M |
Shape Therapeutics Funding History
Shape Therapeutics has raised a total of $148M across 2 funding rounds.
Shape Therapeutics' first fundraising round was a $36M Series A in November 2019. The most recent completed round was a $112M Series B in July 2021.
Shape Therapeutics funding rounds
| Date | Stage | Investors | Raised | Valuation | Deal Summary |
|---|---|---|---|---|---|
| Jul 2021 | Series B | Breton Capital Management (lead); Decheng Capital (lead); Willett Advisors LLC; New Enterprise Associates; Ling Wong; Cherubic Ventures; Mission BioCapital | $112M | - | Shape Therapeutics is a Seattle-based biotechnology company developing RNA technologies, including RNA targeting, editing, and replacement platforms, to address genetic disorders such as Parkinson’s disease, Alzheimer’s disease, alpha-1 antitrypsin deficiency, and Rett syndrome. The company announced a $112 million Series B financing round on July 15, 2021, co-led by Decheng Capital and Breton Capital, with participation from other investors including Cherubic Ventures, Ling Wong, Mission BioCapital, New Enterprise Associates, and Willett Advisors LLC. This round brought total funding to $148 million, following a $35.5 million Series A in 2019. The proceeds from the Series B are intended to expand Shape Therapeutics' portfolio of RNA technologies across industry verticals, accelerate development of gene therapies, and pursue key partnerships to shorten timelines for life-changing medicines. Key platforms include the Shape AAVid capsid discovery platform, which screens billions of engineered AAV variants in non-human primates using AI-driven bioinformatics for tissue-specific targeting, and a human-stable cell line technology for scalable AAV production outperforming standard methods. Additionally, the RNAfix-HTS platform generates and scans large libraries of guide RNAs to promote endogenous ADAR editing. Shape Therapeutics presented advancements at the 24th annual American Society of Gene and Cell Therapy meeting in May 2021, highlighting RNA editing potential for Parkinson’s and next-generation CNS- or muscle-specific AAVs. The company aims to democratize gene therapy by facilitating industry adoption of these technologies for broader patient access. |
| Nov 2019 | Series A | New Enterprise Associates (lead); Tectonic Capital; CureDuchenne Ventures; Ling Wong; Mission BioCapital | $36M | $143M | Shape Therapeutics, Inc. (ShapeTx), a Seattle-based development-stage biotechnology company founded in 2018, specializes in RNA-editing gene therapy platforms, including RNAfix technology that uses natural human cellular machinery to modify RNA, avoiding risks like immunogenicity and off-target damage associated with CRISPR/Cas9. The company announced a $35.5 million Series A financing on November 5, 2019, led by New Enterprise Associates (NEA), with participation from CureDuchenne Ventures, Mission BioCapital, Tectonic Capital, and others including Ling Wong. This funding supported expansion of intellectual property, hiring top scientific talent, and advancing RNA and protein-targeting platforms for curing genetic diseases, coinciding with the formation of a Scientific Advisory Board featuring experts like George Church Ph.D., James Collins Ph.D., and Don Cleveland Ph.D. NEA partner Ed Mathers highlighted the platform's transformative potential, demonstrated in multiple in vivo models, and one of the strongest IP estates in the field. The company has since raised additional rounds, including a $112M Series B in July 2021 with returning investors like NEA and Mission BioCapital, and later Series C funding totaling over $249MM raised to date, with valuations reaching $333.34MM by January 2025. |
Who has invested in Shape Therapeutics?
9 investors have backed Shape Therapeutics across its funding rounds, including New Enterprise Associates, Mission BioCapital, Ling Wong, Cherubic Ventures, Decheng Capital and Tectonic Capital.
Lead investors include Breton Capital Management, Decheng Capital and New Enterprise Associates.
Shape Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 2 | Lead | Nov 2019 | ||
| 2 | Participant | Nov 2019 | ||
| 2 | Participant | Nov 2019 | ||
| 1 | Lead | Jul 2021 | ||
| 1 | Participant | Jul 2021 | ||
| 1 | Participant | Nov 2019 | ||
| 1 | Participant | Nov 2019 | ||
This data is available for Pro users. Sign up to see all 9 Shape Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
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Start Free TrialShape Therapeutics Competitors
Shape Therapeutics competitors include listed companies like Jagsonpal Pharma and Saniona, and private ones like 54gene, Atomic AI, Tahoe Therapeutics and QureBio.
| Company | HQ | Status | Revenue | EBITDA | Valuation |
|---|---|---|---|---|---|
| Publicly listed | $30M | $6M | $157M | ||
| Private | - | - | $162M | ||
| Private | - | - | $125M | ||
| Private | - | - | $120M | ||
| Private | - | - | $174M | ||
| Publicly listed | $44M | $32M | $144M |
Shape Therapeutics Public Comps
Shape Therapeutics is still privately-owned, but its public comps include Saniona, Immunic, Binex, Caribou Biosciences, Corbus Pharmaceuticals, Neumora Therapeutics, Kotra Industries, Panion & Bf Biotech, Mycenax Biotech and NRX Pharmaceuticals.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $44M | $32M | 2.1x | - | 3.0x | (67.1x) | |||
| - | ($98M) | - | - | - | - | |||
| $123M | $9M | 1.7x | 1.6x | 23.9x | 61.8x | |||
| $11M | ($145M) | 4.9x | 2.6x | (0.4x) | (0.4x) | |||
| - | ($84M) | - | 22.4x | (0.3x) | - | |||
| - | ($242M) | - | - | (0.3x) | (0.4x) | |||
| $57M | $16M | 2.4x | 2.4x | 8.6x | 8.3x | |||
| $65M | $14M | 2.3x | - | 10.8x | - | |||
This data is available for Pro users. Sign up to see all Shape Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Shape Therapeutics
| When was Shape Therapeutics founded? | Shape Therapeutics was founded in 2018. |
| Where is Shape Therapeutics headquartered? | Shape Therapeutics is headquartered in Seattle, WA, United States. |
| Is Shape Therapeutics publicly listed? | No, Shape Therapeutics is a private, VC-backed company. |
| What is Shape Therapeutics' valuation? | Shape Therapeutics was last valued at $143M in its Series A in November 2019. |
| How much funding has Shape Therapeutics raised? | Shape Therapeutics has raised $148M across 2 funding rounds. |
| What was Shape Therapeutics' last funding round? | Shape Therapeutics' last funding round was a $112M Series B in July 2021, led by Breton Capital Management and Decheng Capital. |
| Who are Shape Therapeutics' investors? | Shape Therapeutics' investors include New Enterprise Associates, Ling Wong, Mission BioCapital, Breton Capital Management, Willett Advisors LLC, Tectonic Capital, CureDuchenne Ventures, Decheng Capital and Cherubic Ventures. |
| Which companies are comparable to Shape Therapeutics? | Companies comparable to Shape Therapeutics include Jagsonpal Pharma, 54gene, Atomic AI, Tahoe Therapeutics, QureBio and Saniona. |
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