Marea Therapeutics Acquisition, Valuation, Funding & Investors

Marea Therapeutics was acquired by Lisata Therapeutics for $240M in September 2026.

Marea Therapeutics acquisition price

$240M

Acquired by Lisata Therapeutics · Sep 2026

Cumulative funding Marea Therapeutics raised

$255M

across 2 funding rounds

Key investors in Marea Therapeutics

  • Third Rock Ventures
  • Alpha Wave Global
  • Perceptive Advisors
  • Forbion Capital Partners
  • Sofinnova Investments
  • Omega Funds
  • Surveyor Capital
  • venBio Partners

Marea Therapeutics Overview

About Marea Therapeutics

Marea Therapeutics is a San Francisco-headquartered clinical-stage biotechnology company leveraging human genetics discoveries to develop oral therapies for cardiometabolic diseases including obesity and liver conditions. Its lead program targets genetic variants linked to body weight regulation, advancing Phase 1 trials in 2024. Founded in 2022, Marea collaborates with research institutions on polygenic risk platforms to prioritize drug candidates addressing unmet needs in metabolic disorders.


Founded

2022

HQ

United StatesSan Francisco, CA

Status

Acquired

Customer focus

B2B

Revenue model

Product sales

Valuation

$240M (acquired Sep 2026)

Marea Therapeutics Acquisition

Marea Therapeutics was acquired by Lisata Therapeutics for $240M on 17 September 2026.

Before the acquisition Marea Therapeutics had raised $255M across 2 funding rounds.

Lisata Therapeutics acquired Marea Therapeutics on September 17, 2026 in a stock-for-stock merger structured under an Agreement and Plan of Merger. All of Marea’s outstanding equity interests were exchanged for 1,793,129 shares of Lisata common stock and 211,365.213 shares of Series C non-voting convertible preferred stock, representing 213,158,342 Lisata common shares on an as-converted basis and implying an acquisition value of about $240 million. The transaction gave Lisata control of Marea’s cardioendocrine pipeline and repositioned the combined company around first-in-class medicines for cardioendocrine diseases. The deal was paired with a concurrent private placement expected to generate about $225 million of gross proceeds for Lisata through the sale of Series C non-voting convertible preferred stock, supporting development of the combined pipeline and broader clinical plans. Market commentary described the structure as having reverse-merger characteristics, with Marea’s shareholders becoming the majority owners of the combined company. Marea Therapeutics was a clinical-stage biotechnology company focused on human genetics and next-generation medicines for cardioendocrine diseases. Its lead assets included MAR001/005 for severe hypertriglyceridemia and MAR002 for acromegaly, with clinical development programs advancing in 2026. Lisata Therapeutics is a clinical-stage pharmaceutical company listed on Nasdaq, and after the transaction it combined its public listing with Marea’s operating platform and pipeline.

Marea Therapeutics acquisition details
AcquirerDateTypePrice
17 Sep 2026Strategic M&A$240M

Marea Therapeutics Funding History

Marea Therapeutics has raised a total of $255M across 2 funding rounds.

Marea Therapeutics' first fundraising round was a $190M Series B in June 2024. The most recent completed round was a $65M Series A in June 2024.

Marea Therapeutics funding rounds

Marea Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
Jun 2024Series AThird Rock Ventures (lead)$65MMarea Therapeutics, a clinical-stage biotechnology company incubated by Third Rock Ventures, launched on June 18, 2024, with $190 million in combined Series A and Series B financings to develop next-generation medicines for cardiometabolic diseases, including heart attack, diabetes, stroke, and metabolic dysfunction-associated steatohepatitis (MASH). The Series A was led by Third Rock Ventures, while the Series B was led by Sofinnova Investments and co-led by Forbion, Perceptive Xontogeny Venture Fund, and venBio, with participation from Alpha Wave Global, Omega Funds, Surveyor Capital, and Third Rock. The funding will support Phase 2 development of lead program MAR001, a monoclonal antibody inhibiting ANGPTL4 to reduce triglycerides, remnant cholesterol, and ectopic fat while improving insulin sensitivity via subcutaneous injection; the program is in mid-stage clinical trials with a fully enrolled study, planning a Phase IIb in early 2025. Marea also advances undisclosed pipeline candidates targeting other cardiometabolic drivers, leveraging human genetics for first-in-class therapies. Leadership includes CEO Josh Lehrer, M.D., formerly of Graphite Bio and Global Blood Therapeutics; Chief Scientific Officer Robert Weiss from UCSF; Chief Strategy Officer Christine Garrett; and Chief Development Operations Officer Mark Joing. Co-founders are Charles Homcy, M.D. (Third Rock partner emeritus), Sir Stephen O’Rahilly, M.D. (University of Cambridge), and Joshua Rabinowitz, M.D., Ph.D. (Princeton). The board features experienced biotech figures like Ted Love. Marea originated from a 2022 deal with Novartis, which took an equity stake and appointed Shaun Coughlin as board observer; the company operates from San Francisco's MBC BioLabs with about 10 employees at launch.
Jun 2024Series BForbion Capital Partners (lead); Perceptive Advisors (lead); Sofinnova Investments (lead); venBio Partners (lead); Third Rock Ventures; Omega Funds; Alpha Wave Global; Surveyor Capital$190MMarea Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class medicines for cardiometabolic diseases using advances in human genetics. Its lead program, MAR001, is a monoclonal antibody targeting ANGPTL4 to lower remnant cholesterol in adults with metabolic dysfunction and high cardiovascular risk. MAR001 is advancing through Phase 2 clinical development, with an ongoing phase 1b/2a trial nearly fully enrolled showing significant cholesterol reduction and improved biomarkers from single doses. The company also has additional undisclosed pipeline programs targeting other cardiometabolic conditions like heart attack, stroke, diabetes, and MASH. The company launched in June 2024 with $190 million in combined Series A and Series B financings. Third Rock Ventures led the Series A as the founding investor and incubator. The Series B was led by Sofinnova Investments and co-led by Forbion Capital Partners, Perceptive Advisors (Perceptive Xontogeny Venture Fund), and venBio Partners, with participation from Alpha Wave Global, Omega Funds, Surveyor Capital (Citadel), and Third Rock. Funds will support MAR001's Phase 2b study in early 2025 and further pipeline progression. Marea originated from Novartis-licensed technology, co-founded by Third Rock's Charles Homcy, UCSF researcher Ethan Weiss (CSO), Cambridge's Stephen O'Rahilly, and Princeton's Joshua Rabinowitz. CEO Brian Lehrer previously led Graphite Bio. The leadership includes Christine Garrett (Chief Strategy Officer) and Mark Joing (Chief Development Operations). The 10-person team operates from San Francisco's MBC BioLabs, with a board featuring biotech veterans like Ted Love. The funding positions Marea among notable recent cardiovascular biotechs like Verve Therapeutics, amid high interest in novel targets like ANGPTL4 despite past challenges with side effects in preclinical models.

Who has invested in Marea Therapeutics?

8 investors have backed Marea Therapeutics across its funding rounds, including Third Rock Ventures, Alpha Wave Global, Perceptive Advisors, Forbion Capital Partners, Sofinnova Investments and Omega Funds.

Lead investors include Third Rock Ventures, Forbion Capital Partners, Perceptive Advisors, Sofinnova Investments and venBio Partners.


Marea Therapeutics Investors

Investors in Marea Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Third Rock VenturesUnited StatesBoston, MA2LeadJun 2024
Omega FundsUnited StatesBoston, MA1ParticipantJun 2024
venBio PartnersUnited StatesSan Francisco, CA1LeadJun 2024
Sofinnova InvestmentsUnited StatesSan Francisco, CA1LeadJun 2024
Forbion Capital PartnersNetherlandsNaarden1LeadJun 2024
Alpha Wave GlobalUnited StatesMiami, FL1ParticipantJun 2024

This data is available for Pro users. Sign up to see all 8 Marea Therapeutics investors.

Start Free Trial

Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples

Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.

Start Free Trial

Marea Therapeutics Competitors

Marea Therapeutics competitors include listed companies like Dong-A ST, Abclon, Evommune and Abeona Therapeutics, and private ones like Palleon Pharmaceuticals and Watchmaker Genomics.

Public and private companies comparable to Marea Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Dong-A STSouth KoreaSouth KoreaPublicly listed$598M$6M$241M0.8x
AbclonSouth KoreaSouth KoreaPublicly listed$3M($12M)$241M-
Palleon PharmaceuticalsUnited StatesBoston, MAPrivate--$239M-
EvommuneUnited StatesUnited StatesPublicly listed$13M($71M)$241M25.8x
Abeona TherapeuticsUnited StatesUnited StatesPublicly listed$6M($75M)$238M2.4x
Watchmaker GenomicsUnited StatesBoulder, COPrivate--$242M-

Marea Therapeutics Public Comps

Marea Therapeutics is no longer listed, but its public comps include Dong-A ST, Abclon, Evommune, Abeona Therapeutics, Immuneering, ProKidney, Lexeo Therapeutics, Boan Biotech, Amarin Corp and AIM Vaccine.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Dong-A ST$598M$6M0.8x0.8x81.5x9.0x
Abclon$3M($12M)63.0x-(17.7x)-
Evommune$13M($71M)3.7x25.8x(0.7x)(0.4x)
Abeona Therapeutics$6M($75M)19.2x2.4x(1.5x)-
Immuneering-($59M)--(1.6x)-
ProKidney$893K($158M)1306.3x2004.9x(7.4x)(6.4x)
Lexeo Therapeutics-($104M)--(0.3x)(0.3x)
Boan Biotech$118M$19M1.7x1.7x10.2x29.8x

This data is available for Pro users. Sign up to see all Marea Therapeutics competitors and their valuation data.

Start Free Trial

Common questions about Marea Therapeutics

When was Marea Therapeutics founded?Marea Therapeutics was founded in 2022.
Where is Marea Therapeutics headquartered?Marea Therapeutics is headquartered in San Francisco, CA, United States.
Is Marea Therapeutics publicly listed?No, Marea Therapeutics was acquired by Lisata Therapeutics in September 2026.
Who acquired Marea Therapeutics?Marea Therapeutics was acquired by Lisata Therapeutics in September 2026.
How much was Marea Therapeutics acquired for?Marea Therapeutics was acquired for $240M in September 2026.
How much funding has Marea Therapeutics raised?Marea Therapeutics has raised $255M across 2 funding rounds.
What was Marea Therapeutics' last funding round?Marea Therapeutics' last funding round was a $65M Series A in June 2024, led by Third Rock Ventures.
Who are Marea Therapeutics' investors?Marea Therapeutics' investors include Third Rock Ventures, Omega Funds, venBio Partners, Sofinnova Investments, Forbion Capital Partners, Alpha Wave Global, Surveyor Capital and Perceptive Advisors.
Which companies are comparable to Marea Therapeutics?Companies comparable to Marea Therapeutics include Dong-A ST, Abclon, Palleon Pharmaceuticals, Evommune, Abeona Therapeutics and Watchmaker Genomics.

See companies similar to Marea Therapeutics

Start Your
Free Trial Today

Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.

Start Trial