Fore Biotherapeutics Valuation, Funding & Investors

Fore Biotherapeutics is valued at $75M as of September 2020.

Last Fore Biotherapeutics valuation

$75M

Series C · Sep 2020

Last Fore Biotherapeutics funding round

$67M

Series D · Jul 2026

Cumulative funding Fore Biotherapeutics raised

$274M

across 9 funding rounds

Key investors in Fore Biotherapeutics

  • OrbiMed
  • Wellington Management
  • Novartis Venture Fund
  • SR One
  • 3B Future Health Fund
  • Cormorant Asset Management

Fore Biotherapeutics Overview

About Fore Biotherapeutics

Fore Biotherapeutics is a precision oncology biotech headquartered in Cambridge, Massachusetts. The company develops small-molecule therapies targeting undruggable mutations in RAS, PI3K, and MTAP pathways using functional genomics screening. Its lead program advances toward clinical trials for pancreatic and lung cancers. Fore Bio collaborates with academic labs and raised Series A funding in 2023.


Founded

2011

HQ

United StatesPhiladelphia, PA

Website

fore.bio

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

Valuation

$75M (Sep 2020)

Fore Biotherapeutics Valuation

Fore Biotherapeutics is currently valued at $75M, based on its Series C in September 2020. Read the announcement ↗

The $57M round was led by Pontifax, with participation from Novartis Venture Fund, Wellington Management, HBM Healthcare Investments, SR One, OrbiMed and 1 other investor.

Fore Biotherapeutics valuation by funding round

Fore Biotherapeutics valuation by funding round
DateStageValuation
Sep 2020Series C$75M

Fore Biotherapeutics Funding History

Fore Biotherapeutics has raised a total of $274M across 9 funding rounds.

Fore Biotherapeutics' first fundraising round was a $8M seed round in July 2013. The most recent completed round was a $67M Series D in July 2026.

Fore Biotherapeutics funding rounds

Fore Biotherapeutics funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Jul 2026Series DSR One (lead); Novartis Venture Fund; Wellington Management; Axil Capital; LG Technology Ventures; HBM Healthcare Investments; Cormorant Asset Management; SymBiosis; 3B Future Health Fund; Primer Ventures; OrbiMed; Samsung Securities$67M-FORE Biotherapeutics closed an upsized $67.4 million Series D-2 extension financing on July 7, 2026, bringing the total Series D-2 amount raised to $110 million. The round was co-led by SR One, Medicxi, and SymBiosis, with Wellington Management participating as an existing investor alongside OrbiMed Advisors, HBM Healthcare Investments, Novartis Venture Fund, Cormorant Capital, Windham Life Science Partners, Samsung, and 3B Capital. The $72 million second and final tranche completed the transaction, which supports the company's development of plixorafenib, a targeted therapy for cancer patients. FORE Biotherapeutics, a Philadelphia-based registration-stage precision oncology company founded in 2011, has raised more than $255 million since inception. The financing advances plixorafenib's clinical program and strengthens the company's operational capacity as it progresses toward regulatory milestones.
May 2025Series DNovartis Venture Fund; Wellington Management; HBM Healthcare Investments; 3B Future Health Fund; SR One; OrbiMed; Medicxi; Cormorant Asset Management$40M--
Aug 2023Series DMedicxi (lead); SR One (lead); Novartis Venture Fund; Wellington Management; 3B Future Health Fund; HBM Partners; OrbiMed; Cormorant Asset Management; Samsung Securities$75M-FORE Biotherapeutics, an Israeli-American precision oncology company formerly known as NovellusDX, develops cancer therapies using a proprietary functional genomics platform, focusing on plixorafenib, an investigational oral selective inhibitor targeting BRAF alterations in advanced solid and central nervous system tumors. The company closed a $75 million Series D funding round on approximately August 23, 2023, led by SR One and co-led by Medicxi, with participation from existing investors including OrbiMed, HBM Healthcare Investments, Novartis Venture Fund, 3B Future Health Fund, Cormorant Asset Management, Wellington Management, and Samsung Securities. An SEC filing indicated intentions to raise up to $162 million for the round, bringing total funding to $148 million at that point. Proceeds from the Series D are allocated to accelerating clinical development of plixorafenib, following promising Phase 1/2a trial data presented at the ASCO meeting, which showed antitumor activity and favorable tolerability in BRAF-altered tumors. The funding supports progression of the ongoing Phase 2 FORTE global registrational trial. In connection with the financing, Giovanni Mariggi, Partner at Medicxi, joined the board of directors. The round coincided with a CEO transition: Matthew E. Ros stepped down as CEO and board member effective September 1, 2023, with Shawn M. Leland, PharmD, RPh—an advisor to SR One and former Founder, President, and CEO of Elevation Oncology—appointed as interim CEO and board member to oversee operations until a permanent replacement is found. FORE Biotherapeutics is headquartered in Philadelphia with around 40 employees and continues to advance its pipeline in BRAF-altered cancers, including melanomas and primary CNS tumors.
Sep 2020Series CPontifax (lead); Novartis Venture Fund; Wellington Management; HBM Healthcare Investments; SR One; OrbiMed; Cormorant Asset Management$57M$75MFore Biotherapeutics is an Israeli biotechnology company founded in 2011 focused on precision oncology, developing innovative treatments for hard-to-treat cancers. The company's lead asset is plixorafenib (FORE8394), a next-generation, orally available selective inhibitor of BRAF alterations designed to address treatment gaps in BRAF V600 and non-V600 mutations. In a Series D financing completed approximately seven months before planned April 2021 IPO, Fore raised $57 million at a post-money valuation of $75 million, led by Israeli biotech fund Pontifax and co-led by OrbiMed, with each investor acquiring a 12.5% stake. The company planned to go public on Nasdaq aiming for a $500 million valuation and seeking to raise $100 million. Fore had raised $71 million cumulatively since its founding in 2011, with the estimated market size for its flagship drug target estimated at $300-$500 million annually. Following this Series D, the company continued clinical development through subsequent Series D-1 and D-2 financings, raising additional capital to advance the FORTE Master Protocol, a global Phase 2 registrational trial evaluating plixorafenib across multiple patient populations with BRAF alterations.
Apr 2018Series ASICAR (lead); 3B Future Health Fund; Windham Venture Partners; Bio Capital Impact Fund$6M--
Jun 2016SeedOrbiMed (lead)$3M--
Dec 2015Series AIntercure (lead)$10M--
Jul 2014Seed-$8M--
Jul 2013Seed-$8M--

Who has invested in Fore Biotherapeutics?

20 investors have backed Fore Biotherapeutics across its funding rounds, including OrbiMed, Wellington Management, Novartis Venture Fund, SR One, 3B Future Health Fund and Cormorant Asset Management.

Lead investors include SR One, Medicxi, Pontifax, SICAR, OrbiMed and 1 other investor.


Fore Biotherapeutics Investors

Investors in Fore Biotherapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
OrbiMedUnited StatesNew York City, NY5LeadJun 2016
Novartis Venture FundSwitzerlandBeijing4ParticipantSep 2020
Wellington ManagementUnited StatesBoston, MA4ParticipantSep 2020
3B Future Health FundGermanyGermany4ParticipantApr 2018
SR OneUnited StatesUnited States4LeadSep 2020
HBM Healthcare InvestmentsSwitzerlandZug3ParticipantSep 2020
Cormorant Asset ManagementUnited StatesBoston, MA3ParticipantSep 2020
MedicxiUnited KingdomLondon2LeadAug 2023
Samsung SecuritiesSouth KoreaSeoul2ParticipantAug 2023
Axil CapitalJapanTokyo1ParticipantJul 2026
LG Technology VenturesUnited StatesSan Jose, CA1ParticipantJul 2026
Cormorant Asset ManagementUnited StatesBoston, MA1ParticipantJul 2026
SymBiosisUnited StatesBentonville, AR1ParticipantJul 2026

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Fore Biotherapeutics Competitors

Fore Biotherapeutics competitors include listed companies like OKYO Pharma, Eco Animal Health Group, Dicot Pharma and Bioton, and private ones like Cerebral Therapeutics and Sunshine Healthcare Lanka.

Public and private companies comparable to Fore Biotherapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
Cerebral TherapeuticsUnited StatesChicago, ILPrivate--$75M-
OKYO PharmaUnited KingdomUnited KingdomPublicly listed-($8M)$75M-
Eco Animal Health GroupUnited KingdomUnited KingdomPublicly listed$118M$11M$75M0.5x
Dicot PharmaSwedenSwedenPublicly listed-($8M)$75M-
BiotonPolandPolandPublicly listed$72M$13M$76M-
Sunshine Healthcare LankaSri LankaColomboPrivate--$76M-

Fore Biotherapeutics Public Comps

Fore Biotherapeutics is still privately-owned, but its public comps include OKYO Pharma, Eco Animal Health Group, Dicot Pharma, Bioton, Abionyx Pharma, Medivir, Pentixapharm Holding, Oncopeptides, Pyridam Farma and Naturland Holding.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
OKYO Pharma-($8M)--(6.4x)-
Eco Animal Health Group$118M$11M0.5x0.5x5.2x5.2x
Dicot Pharma-($8M)--(6.2x)-
Bioton$72M$13M1.3x-7.1x-
Abionyx Pharma$5M($5M)10.5x10.3x(9.1x)(4.6x)
Medivir$866K($6M)58.9x102.0x(8.4x)(7.3x)
Pentixapharm Holding$104K($18M)667.8x-(3.9x)-
Oncopeptides$7M($23M)10.3x6.0x(3.2x)(4.2x)

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Common questions about Fore Biotherapeutics

When was Fore Biotherapeutics founded?Fore Biotherapeutics was founded in 2011.
Where is Fore Biotherapeutics headquartered?Fore Biotherapeutics is headquartered in Philadelphia, PA, United States.
Is Fore Biotherapeutics publicly listed?No, Fore Biotherapeutics is a private, VC-backed company.
What is Fore Biotherapeutics' valuation?Fore Biotherapeutics was last valued at $75M in its Series C in September 2020.
How much funding has Fore Biotherapeutics raised?Fore Biotherapeutics has raised $274M across 9 funding rounds.
What was Fore Biotherapeutics' last funding round?Fore Biotherapeutics' last funding round was a $67M Series D in July 2026, led by SR One.
Who are Fore Biotherapeutics' investors?Fore Biotherapeutics' investors include OrbiMed, Novartis Venture Fund, Wellington Management, 3B Future Health Fund, SR One, HBM Healthcare Investments, Cormorant Asset Management, Medicxi, Samsung Securities, Axil Capital and 10 others.
Which companies are comparable to Fore Biotherapeutics?Companies comparable to Fore Biotherapeutics include Cerebral Therapeutics, OKYO Pharma, Eco Animal Health Group, Dicot Pharma, Bioton and Sunshine Healthcare Lanka.

See companies similar to Fore Biotherapeutics

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