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- Flywheel.io
Flywheel.io Funding, Investors & Competitors
Flywheel.io has raised $152M across 6 funding rounds, most recently a $28M undisclosed-stage round in December 2025.
Last Flywheel.io funding round
$28M
Undisclosed stage · Dec 2025
Cumulative funding Flywheel.io raised
$152M
across 6 funding rounds
Key investors in Flywheel.io
8VC
Novalis LifeSciences
Beringea
NVentures
Argonautic Ventures
Hewlett Packard Enterprise
Great North Ventures
dRx Capital
About Flywheel.io
Flywheel.io is a cloud platform for biomedical imaging research, managing petabyte-scale datasets for scientists. Built for workflows in neuroscience and oncology, it integrates DICOM storage, AI annotation tools, and containerized compute from partners like NVIDIA. The Seattle-based service accelerates discoveries at institutions including Stanford and Mayo Clinic through collaborative analysis environments.
Founded
2012
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Subscription, Usage-based
Flywheel.io Funding History
Flywheel.io has raised a total of $152M across 6 funding rounds.
Flywheel.io's first fundraising round was a $9M Series A in June 2019. The most recent completed round was a $28M undisclosed-stage round in December 2025.
Flywheel.io funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Dec 2025 | Undisclosed stage | 8VC (lead); Novalis LifeSciences (lead) | $28M | Flywheel.io is a Minneapolis-based medical imaging data management and analysis platform that enables pharmaceutical companies, academic medical centers, and AI developers to aggregate, curate, and analyze large-scale imaging datasets in a cloud-native environment. The platform supports biomedical research, AI model development, and 21 CFR Part 11-compliant clinical trial workflows through tools like Flywheel Validated and video annotation capabilities. It serves 10 of the top 20 global pharmaceutical companies and 10 of the top 20 academic medical centers, positioning it as a key player in HealthTech for clinical trials, medical devices, and AI innovation. In December 2025, Flywheel closed an oversubscribed equity financing round of $27.5 million led by Novalis LifeSciences and 8VC, bringing total funding to $152.8 million. Sources inconsistently report the amount as $25 million or $27.5 million, but the higher figure aligns with the company's PR and multiple outlets. The capital is earmarked to accelerate product innovation, particularly in image management for clinical trials and AI model development, while supporting growth in public sector healthcare, pharma, providers, payers, and system integrators. During 2025, Flywheel reported record growth and launched products including video viewing/annotation tools and Flywheel Validated to streamline compliant workflows, enabling earlier imaging data access, cost reduction, and improved quality for faster decision-making. The company has evolved from core lab research support to an enterprise platform for clinical trials and medical devices. Previous funding includes a $54 million Series D in June 2023 co-led by Novalis LifeSciences and NVentures (NVIDIA), with backers like Microsoft, Novartis, and Intuitive Surgical. Flywheel's infrastructure unlocks imaging data as a strategic asset by integrating management, curation, AI capabilities, and healthcare ecosystem access at scale, accelerating drug development and AI in biopharma. |
| Jan 2025 | Undisclosed stage | - | $20M | Flywheel.io is a Minneapolis-based provider of a cloud-native medical imaging data management and analysis platform that enables pharmaceutical companies, academic medical centers, and innovators to aggregate, curate, and analyze large-scale imaging datasets for biomedical research, clinical trials, AI model development, and medical device markets. The platform includes tools for imaging and video annotation, as well as Flywheel Validated for 21 CFR Part 11-compliant clinical trial workflows. It serves 10 of the top 20 global pharmaceutical companies and 10 of the top 20 academic medical centers. In December 2025, Flywheel closed an oversubscribed equity financing round of $25 million (reported as $27.5 million in the company's press release), led by Novalis LifeSciences and 8VC, with backing from investors including NVIDIA, Microsoft, Novartis, and Intuitive Surgical. The funds are intended to accelerate product development, enhance AI and machine learning integration, scale infrastructure, and expand market reach amid growing demand for imaging management in clinical trials and AI applications. For 2025, Flywheel reported strong traction with 43% year-over-year growth in new business, leading to a 40% increase in committed revenue and 106% growth in ARR from pharmaceutical and medical device customers compared to the prior year; overall net revenue retention exceeded 110%. The company launched new products including video viewing/annotation tools and Flywheel Validated to support clinical trial imaging data analysis. Previous funding includes a $54 million round in 2023 and other rounds totaling around $94 million. No post-money valuation, specific ARR/revenue numbers, EBITDA, or valuation multiples are disclosed for the 2025 round. |
| Jun 2023 | Series D | Novalis LifeSciences (lead); NVentures (lead) | $54M | Flywheel.io is a Minneapolis-based medical imaging data management and AI platform that enables organizations to ingest, curate, analyze, and share complex imaging datasets for accelerated biomedical research, clinical trials, and AI model development. It serves pharmaceutical companies, academic medical centers, providers, payers, and AI developers, with tools like advanced annotation, video support, and 21 CFR Part 11-compliant workflows via Flywheel Validated. The platform integrates with technologies from NVIDIA and Microsoft, including Azure Marketplace and MONAI for scalable clinical AI collaboration. Flywheel serves 10 of the top 20 global pharma companies and top 20 academic centers. On June 27, 2023, Flywheel announced a $54 million Series D funding round co-led by Novalis LifeSciences and NVentures (NVIDIA's venture arm), with participation from 8VC, Beringea, Great North Ventures, Gundersen Health System, Hewlett Packard Enterprise, Intuitive Ventures, Invenshure, Microsoft, Seraph Group, and iSelect, and more to come. The oversubscribed round aims to fuel growth in public sector healthcare and pharma, expand into providers, payers, system integrators, and software firms, and extend global reach, especially in Europe. Marijn Dekkers, Novalis founder and former Bayer/Thermo Fisher CEO, joined the board. Later developments include a $25 million equity round in January 2026 led by Novalis and 8VC, and a $20 million Series D-II in January 2025, contributing to total funding over $130 million across 11 rounds. In 2025, Flywheel reported 43% YoY new business growth, 40% increase in committed revenue, 106% ARR growth from pharma/medical device customers, and >110% net revenue retention, plus a separate $27.5 million equity raise in December 2025. |
| Sep 2021 | Series C | 8VC (lead); Intuitive Ventures (lead) | $27M | Flywheel.io is a cloud-based biomedical research data management platform that enables organizations to ingest, curate, annotate, and share medical imaging data for research, AI development, collaboration, and machine learning workflows in life sciences, pharma, clinical, and academic settings. The company announced its Series C funding on September 15, 2021, initially raising $22 million led by 8VC, with participation from iSelect, Argonautic Ventures, Beringea, DrX/Novartis, HPE Pathfinder, Spike Ventures, Key Investments, Seraph, Great North Labs, and others. Funds were allocated to acquire competitor Radiologics (using about half the initial amount) and expand infrastructure for AI, data exchange, and federated learning. In November 2021, Flywheel closed the Series C at a total of $27.5 million with an additional investment from Intuitive Ventures, the VC arm of Intuitive Surgical, to further develop tools like a discoverable network for data and algorithms to enhance research collaboration and access to real-world data. This Series C followed a $15 million Series B in February 2021 co-led by Beringea and 8VC, with overlapping investors including Novartis dRx Capital, HPE, Great North Labs, iSelect, and Argonautic Ventures, aimed at deepening presence in life sciences and AI markets and accelerating product development for digital transformation in pharma and academia. Flywheel's platform streamlines workflows for clinical trials, imaging research, and bioscience R&D by automating data processes from collection to usability. Later, Flywheel raised a $54 million Series D in June 2023 co-led by Novalis LifeSciences and NVentures (NVIDIA), with participation from Microsoft and prior investors including 8VC, Beringea, Intuitive Ventures, and others, to fuel growth in public sector healthcare, pharma, providers, payers, and global expansion into Europe. CEO Jim Olson emphasized the platform's role in transforming healthcare innovation through efficient data management for AI. |
| Feb 2021 | Series B | 8VC (lead); Beringea (lead); Great North Ventures; dRx Capital; iSelect; Hewlett Packard Enterprise; Argonautic Ventures | $15M | Flywheel.io secured $15 million in Series B funding on February 3, 2021, co-led by Beringea and 8VC, with participation from Novartis dRx Capital, Hewlett Packard Enterprise, Great North Labs, iSelect, and Argonautic Ventures. The company provides a cloud-based data management platform for medical research and collaboration, enabling organizations to streamline research and machine learning workflows in life sciences, clinical, and academic institutions. |
| Jun 2019 | Series A | - | $9M | - |
Who has invested in Flywheel.io?
10 investors have backed Flywheel.io across its funding rounds, including 8VC, Novalis LifeSciences, Beringea, NVentures, Argonautic Ventures and Hewlett Packard Enterprise.
Lead investors include 8VC, Novalis LifeSciences, NVentures, Intuitive Ventures and Beringea.
Flywheel.io Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Feb 2021 | ||
| 2 | Lead | Jun 2023 | ||
| 1 | Participant | Feb 2021 | ||
| 1 | Lead | Jun 2023 | ||
| 1 | Participant | Feb 2021 | ||
| 1 | Participant | Feb 2021 | ||
| 1 | Participant | Feb 2021 | ||
| 1 | Lead | Sep 2021 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialAcquisitions by Flywheel.io
Flywheel.io has acquired 1 company to date.
Last acquisition by Flywheel.io was on September 15th 2021. Flywheel.io acquired Radiologics for undisclosed valuation.
Latest Acquisitions by Flywheel.io
| Description | Radiologics is a Boston-headquartered provider of imaging core lab services for clinical trials in oncology and neurology. The company manages medical image collection, analysis, and archiving using proprietary software platforms compliant with FDA regulations. It supports phase II-IV studies with expertise in MRI, CT, PET, and ultrasound modalities, partnering with sponsors like Pfizer and AstraZeneca. Founded in 2009, Radiologics operates facilities in the US and Europe, processing thousands of images annually for global pharmaceutical trials. |
| HQ Country | |
| HQ City | Saint Louis, MO |
| Deal Date | 15 Sep 2021 |
| Valuation | undisclosed |
| EV/Revenue | |
| EV/EBITDA | |
This data is available for Pro users. Sign up to see all Flywheel.io acquisitions and their M&A valuation multiples. Start Free Trial | |
Flywheel.io Competitors
Flywheel.io competitors include listed companies like GE HealthCare, United Imaging, Glaukos and IQVIA, and private ones like Benchling and Hippocratic AI.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Private | $210M | - | $6.1B | 29.0x | ||
| Publicly listed | $21B | $3.7B | $29B | 1.8x | ||
| Publicly listed | $2.1B | $367M | $12B | 4.8x | ||
| Publicly listed | $507M | ($157M) | $9.5B | 14.6x | ||
| Publicly listed | $16B | $3.4B | $44B | 3.4x | ||
| Private | - | - | $3.5B | - |
Flywheel.io Public Comps
Flywheel.io is still privately-owned, but its public comps include Merck KGaA, IQVIA, Veeva, IDEXX Laboratories, Roper Technologies, Illumina, GE HealthCare, Sartorius, ICON plc and Pro Medicus.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $24B | $5.3B | 3.1x | 3.1x | 14.3x | 10.7x | |||
| $16B | $3.4B | 3.6x | 3.4x | 17.2x | 14.8x | |||
| $3.2B | $965M | 11.1x | 10.2x | 36.9x | 22.4x | |||
| $4.3B | $1.5B | 9.5x | 8.9x | 27.1x | 24.9x | |||
| $7.9B | $3.2B | 6.1x | 5.7x | 15.2x | 14.6x | |||
| $4.3B | $1.4B | 8.8x | 8.4x | 27.1x | 30.0x | |||
| $21B | $3.7B | 1.8x | 1.8x | 10.1x | 10.0x | |||
| $4.1B | $1.1B | 5.7x | 5.4x | 21.8x | 18.2x | |||
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Common questions about Flywheel.io
| When was Flywheel.io founded? | Flywheel.io was founded in 2012. |
| Where is Flywheel.io headquartered? | Flywheel.io is headquartered in Minneapolis, MN, United States. |
| Is Flywheel.io publicly listed? | No, Flywheel.io is a private, VC-backed company. |
| How much funding has Flywheel.io raised? | Flywheel.io has raised $152M across 6 funding rounds. |
| What was Flywheel.io's last funding round? | Flywheel.io's last funding round was a $28M undisclosed-stage round in December 2025, led by 8VC and Novalis LifeSciences. |
| Who are Flywheel.io's investors? | Flywheel.io's investors include 8VC, Novalis LifeSciences, Great North Ventures, NVentures, dRx Capital, iSelect, Hewlett Packard Enterprise, Intuitive Ventures, Argonautic Ventures and Beringea. |
| Which companies are comparable to Flywheel.io? | Companies comparable to Flywheel.io include Benchling, GE HealthCare, United Imaging, Glaukos, IQVIA and Hippocratic AI. |
| How many companies has Flywheel.io acquired? | Flywheel.io has acquired 1 company, including Radiologics. |
See companies similar to Flywheel.io
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