Asceneuron Valuation, Funding & Investors

Asceneuron is valued at $116M as of September 2015.

Last Asceneuron valuation

$116M

Series A · Sep 2015

Last Asceneuron funding round

$100M

Series C · Jul 2024

Cumulative funding Asceneuron raised

$131M

across 2 funding rounds

Key investors in Asceneuron

  • Sofinnova Partners
  • M Ventures
  • Johnson & Johnson Innovation
  • SR One
  • OrbiMed
  • EQT

Asceneuron Overview

About Asceneuron

Asceneuron is a Lausanne-based biopharmaceutical company developing small-molecule therapies for tauopathies and Alzheimer’s disease. Its lead candidate ASN120290 targets OGA enzyme to reduce tau hyperphosphorylation in progressive supranuclear palsy and frontotemporal dementia. The firm advances programs addressing neurofibrillary tangles in FTDP-17 and related disorders. Founded in 2010, Asceneuron raised Series B funding in 2020 and partners with Ferrer for European commercialization of its pipeline.


Founded

2012

HQ

SwitzerlandLausanne

Status

Privately held

Customer focus

B2C

Revenue model

Product sales

Valuation

$116M (Sep 2015)

Asceneuron Valuation

Asceneuron is currently valued at $116M, based on its Series A in September 2015.

The $31M round was led by Sofinnova Partners, with participation from M Ventures, SR One, Kurma Partners and Johnson & Johnson Innovation.

Asceneuron valuation by funding round

Asceneuron valuation by funding round
DateStageValuation
Sep 2015Series A$116M

Asceneuron Funding History

Asceneuron has raised a total of $131M across 2 funding rounds.

Asceneuron's first fundraising round was a $31M Series A in September 2015. The most recent completed round was a $100M Series C in July 2024.

Asceneuron funding rounds

Asceneuron funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Jul 2024Series CNovo Holdings (lead); GSK; M Ventures; EQT; Sofinnova Partners; SR One; OrbiMed; Johnson & Johnson Innovation$100M-Asceneuron is a clinical-stage biotech company based in Switzerland, developing small molecule OGA inhibitors that target tau protein aggregation, a key driver of neurodegenerative diseases including Alzheimer's disease, progressive supranuclear palsy (PSP), Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Its lead asset, ASN51, is an oral small molecule advancing into Phase 2 clinical development for Alzheimer's, while ASN90 (licensed to Ferrer Pharmaceuticals) targets PSP. The company positions itself as a leader in tauopathies with a pipeline addressing high unmet needs in neurodegeneration. On July 16, 2024, Asceneuron secured an oversubscribed $100 million Series C financing led by Novo Holdings, with participation from new investors EQT Life Sciences Dementia Fund, OrbiMed, and SR One, alongside existing backers such as M Ventures, Sofinnova Partners, GSK Equities Investments Limited, and Johnson & Johnson Innovation – JJDC, Inc. The funds will primarily support progression of ASN51 into Phase 2 for Alzheimer's and advancement of its preclinical pipeline in other indications. Novo Holdings' Naveed Siddiqi joined the board, along with representatives from EQT and OrbiMed. The round comes amid a transformative period for Alzheimer's treatments, following FDA approvals of anti-amyloid antibodies like Eli Lilly's Kisunla (donanemab) and Biogen/Eisai's Leqembi, which are injectable therapies. Asceneuron's oral small molecule targeting intracellular tau is highlighted for its potential paradigm shift in treatment. Prior investors also include Alzheimer's Drug Discovery Foundation (ADDF) and Kurma Partners.
Sep 2015Series ASofinnova Partners (lead); M Ventures; SR One; Kurma Partners; Johnson & Johnson Innovation$31M$116MAsceneuron is a clinical-stage biotech company founded in 2012 as a spin-out from Merck Serono through MS Ventures' Entrepreneurship Partnership Program, focusing on small molecule inhibitors targeting O-GlcNAcase (OGA) to address tau protein aggregation in neurodegenerative diseases such as Alzheimer's, Progressive Supranuclear Palsy (PSP), Parkinson's, and ALS. The company's lead asset at the time, ASN-561, was an orally bioavailable OGA inhibitor advancing toward IND-enabling studies and a Phase I trial, with potential as the first oral treatment for tauopathies including orphan conditions like PSP. On September 29, 2015, Asceneuron closed a CHF 30 million (approximately USD 30.6 million) Series A financing round led by Sofinnova Partners, with participation from new investors SR One (GlaxoSmithKline's venture arm), Kurma Partners, Johnson & Johnson Innovation – JJDC, Inc., and existing investor M Ventures (Merck Serono's venture arm). This syndicate joined the board with representatives including Henrijette Richter (Sofinnova), Deborah Harland (SR One), Vanessa Malier (Kurma), and Hakan Goker (M Ventures). The proceeds were designated to advance ASN-561 through completion of a proof-of-concept trial in PSP, expand the pipeline, and support preclinical-to-clinical transition. The round highlighted investor confidence in Asceneuron's science and team, positioning it to build a leading neurodegeneration player. Subsequently, Asceneuron progressed, raising a $100 million oversubscribed Series C in July 2024 led by Novo Holdings, with EQT Life Sciences – LSP Dementia Fund, OrbiMed, SR One, and existing investors including M Ventures, Sofinnova Partners, GSK, and Johnson & Johnson Innovation, to advance lead asset ASN51 into Phase 2 for Alzheimer's and expand preclinical pipelines.

Who has invested in Asceneuron?

9 investors have backed Asceneuron across its funding rounds, including Sofinnova Partners, M Ventures, Johnson & Johnson Innovation, SR One, OrbiMed and EQT.

Lead investors include Novo Holdings and Sofinnova Partners.


Asceneuron Investors

Investors in Asceneuron by funding rounds participated
InvestorHQRoundsRoleFirst check
M VenturesNetherlandsAmsterdam2ParticipantSep 2015
Sofinnova PartnersFranceParis2LeadSep 2015
SR OneUnited StatesUnited States2ParticipantSep 2015
Johnson & Johnson InnovationUnited StatesUnited States2ParticipantSep 2015
GSKUnited KingdomLondon1ParticipantJul 2024
EQTSwedenStockholm1ParticipantJul 2024
Novo HoldingsDenmarkCopenhagen1LeadJul 2024

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Asceneuron Competitors

Asceneuron competitors include listed companies like Sensorion and Kanaph Therapeutics, and private ones like Bioxodes, Cerevance, Longyao Biotech and SciFluor Life Sciences.

Public and private companies comparable to Asceneuron
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
BioxodesBelgiumMarche-en-FamennePrivate--$116M-
CerevanceUnited StatesBoston, MAPrivate--$116M-
Longyao BiotechChinaShanghaiPrivate--$116M-
SciFluor Life SciencesUnited StatesBoston, MAPrivate--$116M-
SensorionFranceFrancePublicly listed-($34M)$115M11.1x
Kanaph TherapeuticsSouth KoreaSouth KoreaPublicly listed$4M($23M)$117M23.2x

Asceneuron Public Comps

Asceneuron is still privately-owned, but its public comps include Sensorion, Kanaph Therapeutics, Genelux, Nanexa, Milestone Pharmaceuticals, Captor Therapeutics, Equillium, Coya Therapeutics, Aardvark Therapeutics and Easywell Biomedicals.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Sensorion-($34M)-11.1x(1.8x)(1.2x)
Kanaph Therapeutics$4M($23M)20.8x23.2x(3.7x)-
Genelux$8K($33M)12305.9x43188.9x(3.0x)(3.7x)
Nanexa$4M$385K29.5x-282.6x-
Milestone Pharmaceuticals$2M($62M)2.2x1.1x(0.1x)-
Captor Therapeutics$1M($10M)82.1x11.3x(10.2x)(23.3x)
Equillium-($23M)--(2.8x)-
Coya Therapeutics$8M($21M)8.6x22.9x(3.2x)-

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Common questions about Asceneuron

When was Asceneuron founded?Asceneuron was founded in 2012.
Where is Asceneuron headquartered?Asceneuron is headquartered in Lausanne, Switzerland.
Is Asceneuron publicly listed?No, Asceneuron is a private, VC-backed company.
What is Asceneuron's valuation?Asceneuron was last valued at $116M in its Series A in September 2015.
How much funding has Asceneuron raised?Asceneuron has raised $131M across 2 funding rounds.
What was Asceneuron's last funding round?Asceneuron's last funding round was a $100M Series C in July 2024, led by Novo Holdings.
Who are Asceneuron's investors?Asceneuron's investors include M Ventures, Sofinnova Partners, SR One, Johnson & Johnson Innovation, GSK, EQT, Novo Holdings, Kurma Partners and OrbiMed.
Which companies are comparable to Asceneuron?Companies comparable to Asceneuron include Bioxodes, Cerevance, Longyao Biotech, SciFluor Life Sciences, Sensorion and Kanaph Therapeutics.

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