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- Amicus Therapeutics
Amicus Therapeutics Acquisition, Valuation & Financials
Amicus Therapeutics was acquired by BioMarin Pharmaceutical for $4.8B in December 2025, a 7.6x multiple on $634M of revenue.
Amicus Therapeutics revenue at acquisition
$634M
Last twelve months · Dec 2025
Amicus Therapeutics revenue multiple at acquisition
7.6x
EV/Revenue · Dec 2025
Amicus Therapeutics EBITDA multiple before the deal
38.8x
EV/EBITDA · last month listed · Mar 2026
About Amicus Therapeutics
Amicus Therapeutics Inc is a biotechnology company focused to develop and deliver transformative medicines for people living with rare diseases. It has a portfolio of product opportunities, including oral precision medicine for people living with Fabry disease who have amenable genetic variants; a clinical-stage, treatment paradigm for Pompe disease, and a rare disease gene therapy portfolio. The company has one segment focused on the discovery, development, and commercialization of therapies to treat a range of devastating rare and orphan diseases.
Founded
2002
HQ
Website
Status
Acquired
Customer focus
B2B
Revenue model
Product sales
Revenue
$634M (Dec 2025)
Valuation
$4.8B (acquired Dec 2025)
Sectors
Amicus Therapeutics Acquisition
Amicus Therapeutics was acquired by BioMarin Pharmaceutical for $4.8B on 19 December 2025.
The acquisition price implies a 7.6x revenue multiple on $634M of revenue.
BioMarin Pharmaceutical, a leader in rare disease therapies, has entered a definitive agreement to acquire Amicus Therapeutics, a biotechnology company specializing in treatments for lysosomal storage disorders, for $4.8 billion in an all-cash transaction at $14.50 per Amicus share. This price represents a 33% premium to Amicus' closing price on December 18, 2025, a 46% premium to the 30-day volume-weighted average, and a 58% premium to the 60-day average. The deal, announced on December 19, 2025, adds two marketed products to BioMarin's portfolio: Galafold (migalastat), the first oral therapy for Fabry disease, and Pombiliti (cipaglucosidase alfa-atga) + Opfolda (miglustat), a two-component enzyme replacement therapy for Pompe disease, which generated combined net product revenues of $599 million over the past four quarters. Amicus also brings DMX-200, a phase 3 investigational small molecule for focal segmental glomerulosclerosis (FSGS), a rare kidney disease. The acquisition strategically expands BioMarin's rare disease franchise, particularly in lysosomal storage disorders, by leveraging its global commercial footprint, manufacturing capabilities, and resources to accelerate market access, label expansions, and revenue growth, with expected increases in long-term CAGR through 2030 and accretive non-GAAP diluted EPS within 12 months of closing. Recent settlements of Galafold patent litigation with Aurobindo Pharma and Lupin secure U.S. exclusivity until early 2037, mitigating generic competition risks. The transaction, unanimously approved by both boards, will be financed via cash on hand and $3.7 billion in non-convertible debt, targeting gross leverage below 2.5x within two years post-close, and is slated to complete in Q2 2026 pending regulatory approvals, Amicus stockholder vote, and customary conditions.
| Acquirer | Date | Type | Price | EV/Revenue |
|---|---|---|---|---|
| 19 Dec 2025 | Strategic M&A | $4.8B | 7.6x |
Amicus Therapeutics as a Public Company
Amicus Therapeutics traded as NAS: FOLD before it was taken private. Its acquisition was announced in December 2025. March 2026 is its last month on record as a listed company, with a market cap of $4.5B and an enterprise value of $4.7B.
Last-twelve-month revenue was $653M, with EBITDA of $121M (19% margin), and the shares traded at 7.2x EV/Revenue and 38.8x EV/EBITDA.
Over the 4 years before that, its market cap grew from $2.7B in March 2022 to $4.5B, while revenue grew from $320M to $653M.
Amicus Therapeutics market cap while listed
Amicus Therapeutics EV/Revenue (LTM) while listed
| As of | Market cap | Revenue (LTM) | EBITDA (LTM) | EBITDA margin | EV/Revenue | EV/EBITDA |
|---|---|---|---|---|---|---|
| Mar 2026 | $4.5B | $653M | $121M | 19% | 7.2x | 38.8x |
| Mar 2025 | $2.5B | $554M | $56M | 10% | 4.9x | 48.8x |
| Mar 2024 | $3.5B | $432M | ($14M) | -3% | 8.4x | (257.2x) |
| Mar 2023 | $3.1B | $346M | ($174M) | -50% | 9.5x | (19.0x) |
| Mar 2022 | $2.7B | $320M | ($189M) | -59% | 8.2x | (13.8x) |
Market cap, enterprise value and last-twelve-month figures are month-end values, up to the last month Amicus Therapeutics traded.
Acquisitions by Amicus Therapeutics
Amicus Therapeutics has acquired 2 companies to date.
Last acquisition by Amicus Therapeutics was on September 20th 2018. Amicus Therapeutics acquired Celenex for $100M.
Latest Acquisitions by Amicus Therapeutics
| Description | Celenex is a biopharmaceutical company developing gene therapies for rare genetic diseases including Friedreich's ataxia and amyotrophic lateral sclerosis. Based in New York, Celenex leverages AAV vectors and CRISPR editing in preclinical pipelines targeting neurological disorders. The firm collaborates with academic institutions for IND-enabling studies. | Scioderm is a clinical-stage biopharma company headquartered in Durham, North Carolina, developing topical therapies for chronic skin diseases like epidermolysis bullosa. Its lead product, Zorblisa, received FDA approval in 2017 as a diaminopyrimidine ointment for wound healing. Scioderm focuses on orphan indications, with trials conducted in the United States and Europe before its acquisition by Citius Pharmaceuticals. |
| HQ Country | ||
| HQ City | Columbus, OH | Durham, NC |
| Deal Date | 20 Sep 2018 | 31 Aug 2015 |
| Valuation | $100M | $847M |
| EV/Revenue | ||
| EV/EBITDA | ||
This data is available for Pro users. Sign up to see all Amicus Therapeutics acquisitions and their M&A valuation multiples. Start Free Trial | ||
Amicus Therapeutics Competitors
Amicus Therapeutics competitors include listed companies like Shanghai RAAS, Hanmi Pharm, Beijing Tongrentang and ACADIA Pharmaceuticals, and private ones like Biocon Biologics and Intas Pharmaceuticals.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $1.1B | $315M | $4.8B | - | ||
| Publicly listed | $1.1B | $234M | $4.8B | 4.0x | ||
| Publicly listed | $2.6B | $447M | $4.7B | 1.9x | ||
| Publicly listed | $1.1B | $119M | $4.7B | 3.2x | ||
| Private | $1.1B | - | $4.5B | 4.2x | ||
| Private | $2B | - | $4.3B | 2.1x |
Amicus Therapeutics Public Comps
Amicus Therapeutics is no longer listed, but its public comps include Shanghai RAAS, Hanmi Pharm, Beijing Tongrentang, ACADIA Pharmaceuticals, Wantai BioPharm, GSK India, Sumitomo Pharma, Gland Pharma, Salubris Pharmaceuticals and Ajanta Pharma.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $1.1B | $315M | 4.7x | - | 16.2x | - | |||
| $1.1B | $234M | 4.3x | 4.0x | 20.9x | 15.5x | |||
| $2.6B | $447M | 1.8x | 1.9x | 10.6x | 12.7x | |||
| $1.1B | $119M | 3.6x | 3.2x | 32.3x | 33.6x | |||
| $271M | ($24M) | 15.5x | - | (174.0x) | - | |||
| $397M | $148M | 11.7x | 11.1x | 31.5x | 32.0x | |||
| $2.9B | $690M | 1.8x | 1.6x | 7.4x | 6.2x | |||
| $668M | $179M | 7.0x | 6.5x | 26.2x | 24.9x | |||
This data is available for Pro users. Sign up to see all Amicus Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Amicus Therapeutics
| When was Amicus Therapeutics founded? | Amicus Therapeutics was founded in 2002. |
| Where is Amicus Therapeutics headquartered? | Amicus Therapeutics is headquartered in Cranbury, NJ, United States. |
| Is Amicus Therapeutics publicly listed? | No, Amicus Therapeutics was acquired by BioMarin Pharmaceutical in December 2025. |
| Who acquired Amicus Therapeutics? | Amicus Therapeutics was acquired by BioMarin Pharmaceutical in December 2025. |
| How much was Amicus Therapeutics acquired for? | Amicus Therapeutics was acquired for $4.8B in December 2025, a 7.6x revenue multiple. |
| Which companies are comparable to Amicus Therapeutics? | Companies comparable to Amicus Therapeutics include Shanghai RAAS, Hanmi Pharm, Beijing Tongrentang, ACADIA Pharmaceuticals, Biocon Biologics and Intas Pharmaceuticals. |
| What was Amicus Therapeutics' market cap before the acquisition? | Amicus Therapeutics had a market cap of $4.5B in March 2026, its last month on record as a listed company, trading at 7.2x EV/Revenue. |
| What was Amicus Therapeutics' revenue as a public company? | Amicus Therapeutics' last reported twelve-month revenue was $653M (March 2026), with EBITDA of $121M. |
| How many companies has Amicus Therapeutics acquired? | Amicus Therapeutics has acquired 2 companies, including Celenex and Scioderm. |
| What was the largest acquisition by Amicus Therapeutics? | The $847M acquisition of Scioderm in August 2015 is the largest acquisition Amicus Therapeutics has made to date. |
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